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21c Museum Hotel, Louisville

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Art Museum · Hidden Gem · Art Gallery
Nestled in downtown Louisville on historic West Main Street, along Museum Row, 21c Museum Hotel is a multi-venue contemporary art museum, an award-winning 91-room boutique hotel, and home to acclaimed Proof on Main restaurant, led by executive chef Mike Wajda. Stay with us and the iconic Red Penguin.
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21c Museum Hotel reviews

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TripAdvisor traveler rating 4.5
334 reviews
  • Stopped in for a drink and a stamp on my Urban Bourbon Trail passport. Great service and friendly conversation.  more »
  • We had a lot of issues with this hotel - the rooms, the communication with the front desk, etc. A big thank you to David Hall for helping us out and resolving our problems. The rest of the staff...  more »
  • Such a great place to pop in when walking around. The art was beautiful and very well displayed. Numerous rooms holding various treasures and a refreshment bar with soft drinks, coffee, tea and sparkling water offered to guests free of charge! Free museum and free refreshments! Wow. I particularly loved the boats crafted by the heart doctor. Very similar to the precise moves you make doing heart surgery, making large scale boats fine tunes those skills. It’s a must do when in the area! Staff are kind and courteous. Everyone wears a smile and gleaming eyes.
  • I love this hotel/gallery concept. This is the first 21C Hotel and it is situated in downtown Louisville. Proof On Main is one of the restaurant concepts within the building and it is excellent food, service, and atmosphere. The upstairs and lower floor galleries included great exhibitions and the art installations on the main floor in common areas were all interesting and engaging. Overall, I couldn't ask for more, and had an overall great experience. I would recommend this for any traveler!
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