60 days in South America, Mexico & United States Itinerary

60 days in South America, Mexico & United States Itinerary

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Route & dates

Start: New York City, United States
Fly:  6 h 30 min
1
Cartagena, Colombia
— 4 nights
Fly:  3 h 15 min
2
San Andres Island, Colombia
— 6 nights
Fly:  7 h 45 min
3
La Paz, Bolivia
— 3 nights
Fly:  2 h 45 min
4
Sucre, Bolivia
— 2 nights
Fly:  5 h 15 min
5
Uyuni, Bolivia
— 1 night
Fly:  11 h 30 min
6
Bogota, Colombia
— 5 nights
Fly:  1 h 15 min
7
Medellin, Colombia
— 6 nights
Fly:  7 h 15 min
8
Playa del Carmen, Mexico
— 5 nights
Taxi:  2 h
9
Cozumel, Mexico
— 6 nights
Fly:  4 h 15 min
10
Mexico City, Mexico
— 6 nights
Fly:  3 h 15 min
11
Puerto Vallarta, Mexico
— 6 nights
Fly:  7 h 30 min
12
Seattle, United States
— 6 nights
Fly:  8 h 45 min
End: New York City, United States

4
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Shop till you drop at NH Galeria and Centro Comercial Viva Barranquilla. Next up on the itinerary: steep yourself in history at Walled City of Cartagena, gain insight at Plaza Santo Domingo, admire the landmark architecture of Claustro de la Merced Mausoleo de Garcia Marquez, and get a new perspective on things with Boat Tours & Water Sports.

To find more things to do, traveler tips, maps, and other tourist information, use the Cartagena attractions website.

New York City, USA to Cartagena is an approximately 9-hour flight. Prepare for warmer weather when traveling from New York City in March: high temperatures in Cartagena hover around 89°F and lows are around 77°F. Cap off your sightseeing on the 5th (Thu) early enough to travel to San Andres Island.

Things to do in Cartagena

Historic Sites Shopping Tours

Side Trip

Centro Comercial Viva Barranquilla
Highlights from your plan
Walled City of Cartagena ©
Walled City of Cartagena
El Centro Artesano ©
El Centro Artesano
Centro Comercial Viva Barranquilla ©
Centro Comercial Viva Barranquilla

6
nights
San Andres Island, Colombia

San Andres Island ©
The coral San Andres Island boasts a rich colonial history, exotic beaches, and a laidback, tropical lifestyle.
Shop till you drop at Banco de la Republica and Esmeraldas Colombianas. There's still lots to do: head off the coast to Johnny Cay, stroll through Cocoplum Bay, explore the gorgeous colors at West View, and take in the dramatic natural features at Hoyo Soplador.

To find more things to do, ratings, other places to visit, and tourist information, go to the San Andres Island itinerary planner.

You can fly from Cartagena to San Andres Island in 3.5 hours. Expect a daytime high around 85°F in March, and nighttime lows around 77°F. Cap off your sightseeing on the 11th (Wed) early enough to travel to La Paz.

Things to do in San Andres Island

Parks Outdoors Beaches
Highlights from your plan
Johnny Cay ©
Johnny Cay
Banco de la Republica ©
Banco de la Republica
Esmeraldas Colombianas ©
Esmeraldas Colombianas

3
nights
La Paz, Bolivia

La Paz ©
Take a moment to catch your breath as you commence your holiday in La Paz.
Go for a jaunt from La Paz to Tiahuanaco to see Puma Punku about 1h 10 min away. Spend the 14th (Sat) exploring the striking scenery along WMDR Yungas Road. Next up on the itinerary: delve into the distant past at Tiwanaku, don't miss a visit to Mercado de Las Brujas, look for gifts at Mistura - Manifestacion Creativa, and get outside with Outdoor Activities.

For where to stay, maps, ratings, and tourist information, read our La Paz vacation maker.

Getting from San Andres Island to La Paz by flight takes about 10.5 hours. Due to the time zone difference, you'll lose 1 hour traveling from San Andres Island to La Paz. Traveling from San Andres Island in March, things will get colder in La Paz: highs are around 59°F and lows about 38°F. Cap off your sightseeing on the 15th (Sun) early enough to travel to Sucre.

Things to do in La Paz

Outdoors Scenic Drive Historic Sites

Side Trip

Puma Punku
Highlights from your plan
WMDR Yungas Road ©
WMDR Yungas Road
Mistura - Manifestacion Creativa ©
Mistura - Manifestacion Creativa
Tiwanaku ©
Tiwanaku

2
nights
Sucre, Bolivia

Sucre ©
The constitutional capital of Bolivia, Sucre has a well-preserved historic center, with many buildings dating back to the city's founding in the 16th century.
On the 16th (Mon), stop by Mercado de Tarabuco, thenget engrossed in the history at House of Liberty Museum - Casa de la Libertad, and then examine the collection at Museum of Indigenous Art ASUR. Get ready for a full day of sightseeing on the 17th (Tue): shop like a local with Arte y Cultura Sucre Galeria, take in breathtaking views at Icla Canyon, and then don't miss a visit to Cal Orck'o.

To find photos, more things to do, other places to visit, and other tourist information, go to the Sucre online trip itinerary maker.

You can fly from La Paz to Sucre in 3 hours. Other options are to drive; or take a bus. Traveling from La Paz in March, expect Sucre to be somewhat warmer, temps between 69°F and 50°F. Wrap up your sightseeing on the 17th (Tue) to allow time to travel to Uyuni.

Things to do in Sucre

Museums Shopping Nature
Highlights from your plan
Museum of Indigenous Art ASUR ©
Museum of Indigenous Art ASUR
Mercado de Tarabuco ©
Mercado de Tarabuco
Arte y Cultura Sucre Galeria ©
Arte y Cultura Sucre Galeria

1
night
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
On the 18th (Wed), step off the mainland to explore Isla Incahuasi and then take in the dramatic natural features at Salar de Uyuni.

For more things to do, maps, traveler tips, and other tourist information, go to the Uyuni sightseeing planning app.

Traveling by flight from Sucre to Uyuni takes 6.5 hours. Alternatively, you can drive; or do a combination of bus and taxi. When traveling from Sucre in March, plan for slightly colder days and about the same nights in Uyuni: temperatures range from 50°F by day to 46°F at night. Finish your sightseeing early on the 18th (Wed) so you can travel to Bogota.

Things to do in Uyuni

Nature Parks
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi

5
nights
Bogota, Colombia

Bogota ©
Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Do your shopping at Multiplaza Bogota and Vinos Express. Step out of Bogota to go to Zipaquira and see Catedral de Sal de Zipaquira, which is approximately 54 minutes away. There's still lots to do: see the interesting displays at Gold Museum (Museo del Oro), hunt for treasures at Mercado de las Pulgas de Usaquen, get into the urban bustle at Centro Internacional de Negocios y Exposiciones, and experience the excitement of Whee Institute - Learn Spanish in Bogota.

For ratings, photos, where to stay, and more tourist information, refer to the Bogota trip itinerary planning tool.

Getting from Uyuni to Bogota by flight takes about 11.5 hours. Other options: drive; or do a combination of taxi and bus. Traveling from Uyuni to Bogota, you'll gain 1 hour due to the time zone difference. Traveling from Uyuni in March, expect nights in Bogota to be about the same, around 48°F, while days are somewhat warmer, around 68°F. Finish your sightseeing early on the 24th (Tue) to allow enough time to travel to Medellin.

Things to do in Bogota

Shopping Museums Classes

Side Trips

Catedral de Sal de Zipaquira, Centro de Memoria El Cuartico, Vinos Express
Highlights from your plan
Vinos Express ©
Vinos Express
Mercado de las Pulgas de Usaquen ©
Mercado de las Pulgas de Usaquen
Galeria La Cometa ©
Galeria La Cometa

6
nights
Medellin, Colombia

Medellin ©
Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Head to Duna Store and Mayorca Mega Plazafor some retail therapy. There's still lots to do: get the lay of the land with Walking tours, contemplate the waterfront views at Laguna de Guatape, admire the striking features of Centro Cultural Moravia, and glide through the air with a parasailing or paragliding tour.

To see other places to visit, photos, maps, and other tourist information, go to the Medellin tour itinerary planner.

Traveling by flight from Bogota to Medellin takes 3.5 hours. Alternatively, you can drive; or take a bus. In March, Medellin is a bit warmer than Bogota - with highs of 82°F and lows of 65°F. Cap off your sightseeing on the 30th (Mon) early enough to travel to Playa del Carmen.

Things to do in Medellin

Tours Outdoors Parks

Side Trip

Mayorca Mega Plaza
Highlights from your plan
medellin 2000m DESCENT ©
medellin 2000m DESCENT
Mayorca Mega Plaza ©
Mayorca Mega Plaza
Duna Store ©
Duna Store

5
nights
Playa del Carmen, Mexico

Playa del Carmen ©
The tourist hub of the popular Mayan Riviera, upscale Playa del Carmen remains the jewel of Mexico's Caribbean coastline.
Head to La Isla Shopping Village and Mercado 28for some retail therapy. Explore the numerous day-trip ideas around Playa del Carmen: Tulum (Cenotes Sac Actun, Balam Art On Feathers, &more). And it doesn't end there: find something for the whole family at Xcaret, kick your exploration up a notch at some of the top local zipline courses and adventure parks, tee off at Playacar Golf Club, and explore the world behind art at Gaston Charo Art Gallery Playa del Carmen.

To see ratings, where to stay, and tourist information, refer to the Playa del Carmen online trip builder.

Traveling by flight from Medellin to Playa del Carmen takes 8 hours. In March, daily temperatures in Playa del Carmen can reach 81°F, while at night they dip to 66°F. Cap off your sightseeing on the 5th (Sun) early enough to travel to Cozumel.

Things to do in Playa del Carmen

Outdoors Tours Adventure

Side Trips

Tulum, Cancun
Highlights from your plan
Tulum Archaeological Site ©
Tulum Archaeological Site
La Isla Shopping Village ©
La Isla Shopping Village
Mercado 28 ©
Mercado 28

6
nights
Cozumel, Mexico

Thanks to the island's outstanding scuba diving and snorkeling options, Cozumel tourism sector remains a major employer and the main source of income for this Caribbean getaway.
Cozumel is known for wildlife, outdoors, and theme parks. Your plan includes some of its best attractions: head outdoors with Outdoor Activities, partake in some friendly competition at The Amazing Cozumel Race, stroll through Palancar Reef, and explore the ancient world of San Gervasio Mayan Archaeological Site.

To see reviews, more things to do, and more tourist information, read our Cozumel trip planner.

You can drive from Playa del Carmen to Cozumel in 2 hours. April in Cozumel sees daily highs of 83°F and lows of 70°F at night. Wrap up your sightseeing on the 11th (Sat) early enough to travel to Mexico City.

Things to do in Cozumel

Wildlife Parks Outdoors
Highlights from your plan
Scuba & Snorkeling
Black Coral Shop ©
Black Coral Shop
San Gervasio Mayan Archaeological Site ©
San Gervasio Mayan Archaeological Site

6
nights
Mexico City, Mexico

Mexico City ©
Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Head to Casa Fusion and Arto Otrafor some retail therapy. Change things up with these side-trips from Mexico City: Cuernavaca (Spanish Language Institute - Day Course & Robert Brady Museum) and San Juan Teotihuacan (Piramide de la Serpiente Emplumada & Zona Arqueológica de Teotihuacan Estacionamiento Puerta 5). The adventure continues: take an in-depth tour of Museo Nacional de Antropologia, explore the ancient world of Museo del Templo Mayor, steep yourself in history at Basilica de Santa Maria de Guadalupe, and step into the grandiose world of Chapultepec Castle.

To find ratings, more things to do, maps, and more tourist information, refer to the Mexico City trip planner.

Getting from Cozumel to Mexico City by flight takes about 4.5 hours. Other options: do a combination of taxi and bus. You'll gain 1 hour traveling from Cozumel to Mexico City due to the time zone difference. Traveling from Cozumel in April, expect little chillier with lows of 56°F in Mexico City. Wrap up your sightseeing on the 17th (Fri) to allow time to travel to Puerto Vallarta.

Things to do in Mexico City

Historic Sites Museums Breweries & Distilleries

Side Trips

Cuernavaca, San Juan Teotihuacan
Highlights from your plan
Casa Fusion ©
Casa Fusion
Arto Otra ©
Arto Otra

6
nights
Puerto Vallarta, Mexico

Boasting a coastline made for perfectly framed photographs of romantic sunsets, Puerto Vallarta continuously ranks among the world's top tourist resorts.
Shop till you drop at Galleria Dante and A Broken Art. Explore Puerto Vallarta's surroundings by going to Bucerias (Bucerias Art Gallery, Spas & Wellness, &more) and Vallarta Botanical Gardens (in Cabo Corrientes). The adventure continues: take a leisurely stroll along Malecon Boardwalk, appreciate the extensive heritage of Zona Romantica, view the masterpieces at Ro'Wo Galeria, and step off the mainland to explore Marietas Islands.

To find where to stay and other tourist information, refer to the Puerto Vallarta itinerary maker tool.

Fly from Mexico City to Puerto Vallarta in 3.5 hours. Alternatively, you can drive; or take a bus. Expect a bit warmer evenings in Puerto Vallarta when traveling from Mexico City in April, with lows around 67°F. Finish your sightseeing early on the 23rd (Thu) to allow enough time to travel to Seattle.

Things to do in Puerto Vallarta

Tours Shopping Museums

Side Trips

Bucerias, Marietas Islands, Vallarta Botanical Gardens
Highlights from your plan
Zipline
Art in Amber ©
Art in Amber
Galleria Dante ©
Galleria Dante

6
nights
Seattle, United States

Seattle ©
Nicknamed the "Emerald City" because of its abundant evergreen trees, Seattle is the cultural and business center of the Pacific Northwest, as well as a popular holiday destination.
Head to Chihuly Garden and Glass and Elliott Bay Book Companyfor some retail therapy. There's much more to do: shop like a local with Pike Place Market, get up close and personal with brilliant marine life at Seattle Aquarium, take a stroll through Bellevue Square, and see the interesting displays at The Museum of Flight.

To find more things to do, other places to visit, where to stay, and other tourist information, read our Seattle planning app.

You can fly from Puerto Vallarta to Seattle in 8 hours. Alternatively, you can drive; or take a bus. Traveling from Puerto Vallarta to Seattle, you'll gain 2 hours due to the time zone difference. Expect cooler temperatures when traveling from Puerto Vallarta in April; daily highs in Seattle reach 61°F and lows reach 46°F. On the 29th (Wed), you'll have the morning to explore before heading back home.

Things to do in Seattle

Shopping Neighborhoods Museums

Side Trip

Bellevue Square
Highlights from your plan
Chihuly Garden and Glass ©
Chihuly Garden and Glass
Pike Place Market ©
Pike Place Market
Elliott Bay Book Company ©
Elliott Bay Book Company

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