60 days in South America Itinerary

60 days in South America Itinerary

Created using Inspirock South America sightseeing planner

Travel Warning: Security Concerns   More Info
Make it your trip
Drive
1
Pereira, Colombia
— 1 night
Drive
2
Medellin, Colombia
— 2 nights
Drive
3
Cartagena, Colombia
— 1 night
Drive
4
Santa Marta, Colombia
— 2 nights
Drive
5
Maracaibo, Venezuela
— 2 nights
Drive
6
Caracas, Venezuela
— 3 nights
Drive
7
Ciudad Guayana, Venezuela
— 1 night
Drive
8
Boa Vista, Brazil
— 1 night
Drive
9
Manaus, Brazil
— 3 nights
Drive
10
Ariquemes, Brazil
— 1 night
Drive
11
Vilhena, Brazil
— 1 night
Drive
12
Sinop, Brazil
— 1 night
Drive
13
Canarana, Brazil
— 1 night
Drive
14
Araguacema, Brazil
— 1 night
Drive
15
Maraba, Brazil
— 1 night
Drive
16
Sao Luis, Brazil
— 2 nights
Drive
17
Fortaleza, Brazil
— 3 nights
Drive
18
Natal, Brazil
— 2 nights
Drive
19
Porto de Galinhas, Brazil
— 2 nights
Drive
20
Salvador, Brazil
— 1 night
Drive
21
Guanambi, Brazil
— 1 night
Drive
22
Brasilia, Brazil
— 2 nights
Drive
23
Belo Horizonte, Brazil
— 1 night
Drive
24
Rio de Janeiro, Brazil
— 3 nights
Drive
25
Sao Paulo, Brazil
— 3 nights
Drive
26
Curitiba, Brazil
— 2 nights
Drive
27
Puerto Iguazu, Argentina
— 2 nights
Drive
28
Asuncion, Paraguay
— 3 nights
Drive
29
Encarnacion, Paraguay
— 2 nights
Drive
30
Salto, Uruguay
— 2 nights
Drive
31
Montevideo, Uruguay
— 3 nights
Drive
32
Colonia del Sacramento, Uruguay
— 2 nights
Drive
33
Gualeguaychu, Argentina
— 1 night
Drive

S M T W T F S
25
26
27
28
29
30
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
1
2
3

Pereira, Colombia

— 1 night
A center of commerce and trade, the thriving city of Pereira was founded in 1863.
Start off your visit on the 30th (Fri): examine the collection at Museo de Arte de Pereira.

For where to stay, reviews, maps, and tourist information, read Pereira trip planning app.

Bogota to Pereira is an approximately 3-hour flight. You can also do a combination of flight and bus; or drive. In April, Pereira is somewhat warmer than Bogota - with highs of 32°C and lows of 20°C. Finish up your sightseeing early on the 1st (Sat) so you can catch the flight to Medellin.

Things to do in Pereira

Museums
Highlights from your trip

Medellin, Colombia

— 2 nights

City of the Eternal Spring

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Start off your visit on the 1st (Sat): identify plant and animal life at Parque Arvi, then stroll around Parques del Rio, and then contemplate the long history of Pueblito Paisa. On the 2nd (Sun), you'll have a packed day of sightseeing: get engrossed in the history at Museo de Antioquia, then pause for some serene contemplation at Templo Parroquial Jesus Nazareno, then glide through the air with a parasailing or paragliding tour, and finally indulge in some personalized pampering at some of the best spas.

To find out how to plan a trip to Medellin, use our trip itinerary maker.

Getting from Pereira to Medellin by flight takes about 3 hours. Other options: drive; or take a bus. May in Medellin sees daily highs of 32°C and lows of 20°C at night. Finish up your sightseeing early on the 3rd (Mon) so you can catch the flight to Cartagena.

Things to do in Medellin

Parks · Wildlife · Historic Sites · Museums

Cartagena, Colombia

— 1 night

City of Heroes

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Kick off your visit on the 3rd (Mon): pause for some serene contemplation at Catedral Santa Catalina de Alejandria and then contemplate the long history of Walled City of Cartagena.

For maps, where to stay, other places to visit, and more tourist information, you can read our Cartagena online tour planner.

Traveling by flight from Medellin to Cartagena takes 3 hours. Alternatively, you can drive; or take a bus. Traveling from Medellin in May, things will get a bit warmer in Cartagena: highs are around 38°C and lows about 30°C. Finish your sightseeing early on the 4th (Tue) to allow enough time to drive to Santa Marta.

Things to do in Cartagena

Historic Sites

Santa Marta, Colombia

— 2 nights

America's Pearl

Many visitors begin their Santa Marta holiday, surrounded by urban clutter and heavy traffic, expecting little from the city in terms of historical importance.
On the 4th (Tue), discover the deep blue sea with a scuba or snorkeling tour. On your second day here, admire the masterpieces at Quinta de San Pedro Alejandrino, then tour the pleasant surroundings at Playa Blanca, and then take in the architecture and atmosphere at Catedral de Santa Marta.

For where to stay, more things to do, and other tourist information, use the Santa Marta road trip planning website.

Getting from Cartagena to Santa Marta by car takes about 3.5 hours. Other options: take a bus. In May, daily temperatures in Santa Marta can reach 39°C, while at night they dip to 30°C. Finish your sightseeing early on the 6th (Thu) so you can travel to Maracaibo.

Things to do in Santa Marta

Outdoors · Wildlife · Tours · Museums

Maracaibo, Venezuela

— 2 nights

Beloved Land of the Sun

Home to more than 2 million residents, Maracaibo boasts giant shopping malls and attractive parks, as well as a modern skyline that hugs the shore of an eponymous lake.
On the 6th (Thu), Head underground at Cuevas de Saman and then pause for some serene contemplation at Basílica de Nuestra Señora del Rosario de Chiquinquirá. Get ready for a full day of sightseeing on the 7th (Fri): see the interesting displays at Museo Historico Rafael Urdaneta, indulge in some personalized pampering at Calantha Spa, and then walk around La vereda del lago Maracaibo.

To see ratings, where to stay, traveler tips, and other tourist information, you can read our Maracaibo route builder website.

You can drive from Santa Marta to Maracaibo in 7 hours. Due to the time zone difference, you'll lose 1 hour traveling from Santa Marta to Maracaibo. In May, daily temperatures in Maracaibo can reach 39°C, while at night they dip to 30°C. Finish your sightseeing early on the 8th (Sat) so you can fly to Caracas.

Things to do in Maracaibo

Parks · Museums · Historic Sites · Nature

Caracas, Venezuela

— 3 nights

Heaven's Branch on Earth

Tropical weather, great food, and memorable jungle surroundings seem like all the ingredients Caracas needs to become a must-see destination.
Visit Casa Natal & Museo Bolivar and Basilica Menor Santa Capilla for their historical value. Visiting Parque Nacional el Avila and Hacienda La Trinidad Parque Cultural will get you outdoors. There's still lots to do: admire the masterpieces at Museo de Bellas Artes, take in the architecture and atmosphere at Iglesia Sagrado Corazon de Jesus, don't miss a visit to Mercado Municipal de Chacao, and get a taste of the local shopping with Plaza Francia.

For reviews, more things to do, where to stay, and more tourist information, read Caracas road trip website.

You can fly from Maracaibo to Caracas in 2.5 hours. Alternatively, you can drive; or take a bus. Finish your sightseeing early on the 11th (Tue) to allow enough time to fly to Ciudad Guayana.

Things to do in Caracas

Museums · Outdoors · Shopping · Historic Sites

Ciudad Guayana, Venezuela

— 1 night
Located on the Orinoco River, Ciudad Guayana represents one of Venezuela's fastest-growing cities, with plenty of natural and man-made highlights on offer.
On the 11th (Tue), browse the different shops at Orinokia mall and then pause for some serene contemplation at Iglesia Virgen del Valle.

To see more things to do, ratings, photos, and tourist information, refer to the Ciudad Guayana trip builder app.

Traveling by flight from Caracas to Ciudad Guayana takes 2.5 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Caracas to Ciudad Guayana is minus 1 hour. Finish up your sightseeing early on the 12th (Wed) so you can travel to Boa Vista.

Things to do in Ciudad Guayana

Shopping · Historic Sites

Boa Vista, Brazil

— 1 night
The capital of the state of Roraima, and home to roughly half its population, the planned city of Boa Vista was established in 1890 and designed according to an innovative radial shape.
For photos, traveler tips, other places to visit, and tourist information, read Boa Vista trip planner.

Traveling by car from Ciudad Guayana to Boa Vista takes 13.5 hours. Traveling from Ciudad Guayana to Boa Vista, you'll lose 1 hour due to the time zone difference. In May, daytime highs in Boa Vista are 36°C, while nighttime lows are 27°C. You will leave for Manaus on the 13th (Thu).

Things to do in Boa Vista

Parks · Nature · Outdoors · Nightlife

Manaus, Brazil

— 3 nights

Paris of the Tropics

It's hard not to get excited when planning a trip to Manaus, capital of the state of Amazonas, and the largest city on the mighty Amazon River.
On the 14th (Fri), get a new perspective on nature at Museu da Amazonia (MUSA), then stroll through Ponta Negra Beach, then browse the different shops at Manauara Shopping, and finally pause for some serene contemplation at Paroquia Nossa Senhora de Fatima. Here are some ideas for day two: look for all kinds of wild species at Arquipelago de Anavilhanas, add some adventure to your tour with a kayaking and canoeing tour, and then make a trip to Espaco Cultural Largo de Sao Sebastiao.

To find other places to visit, maps, where to stay, and more tourist information, go to the Manaus trip app.

Traveling by car from Boa Vista to Manaus takes 12 hours. Expect a daytime high around 35°C in May, and nighttime lows around 28°C. Finish your sightseeing early on the 16th (Sun) to allow enough time to travel to Ariquemes.

Things to do in Manaus

Wildlife · Outdoors · Parks · Tours

Ariquemes, Brazil

— 1 night
Ariquemes is a municipality located in the Brazilian state of Rondônia. To see where to stay, more things to do, photos, and other tourist information, you can read our Ariquemes trip planner.

The Route module can help you plan travel from Manaus to Ariquemes. May in Ariquemes sees daily highs of 36°C and lows of 27°C at night. You will leave for Vilhena on the 17th (Mon).

Things to do in Ariquemes

Museums · Parks

Vilhena, Brazil

— 1 night
Vilhena is the easternmost municipality in the Brazilian state of Rondônia. Kick off your visit on the 17th (Mon): browse the different shops at Park Shopping Vilhena, examine the collection at House of Rondon, and then pause for some serene contemplation at Igreja De Nossa Senhora Aparecida.

To see reviews, other places to visit, where to stay, and other tourist information, use the Vilhena tour itinerary maker.

Drive from Ariquemes to Vilhena in 7.5 hours. Alternatively, you can fly. Plan for a bit cooler nights when traveling from Ariquemes in May since evenings lows in Vilhena dip to 23°C. Finish up your sightseeing early on the 18th (Tue) so you can travel to Sinop.

Things to do in Vilhena

Museums · Historic Sites · Shopping

Sinop, Brazil

— 1 night
Kick off your visit on the 18th (Tue): pause for some serene contemplation at Catedral Sagrado Coracao de Jesus.

For ratings, other places to visit, more things to do, and other tourist information, read our Sinop day trip website.

Traveling by car from Vilhena to Sinop takes 11 hours. Alternatively, you can fly. Finish up your sightseeing early on the 19th (Wed) so you can travel to Canarana.

Things to do in Sinop

Historic Sites
Highlights from your trip

Canarana, Brazil

— 1 night
Kick off your visit on the 19th (Wed): make a trip to Igreja Matriz Nossa Senhora Auxiliadora.

To find ratings, traveler tips, maps, and other tourist information, read Canarana trip maker site.

Use the Route module to find suitable travel options from Sinop to Canarana. Finish your sightseeing early on the 20th (Thu) so you can travel to Araguacema.
Highlights from your trip

Araguacema, Brazil

— 1 night
Araguacema is a municipality located in the Brazilian state of Tocantins. For traveler tips, ratings, maps, and more tourist information, use the Araguacema trip planner.

You can drive from Canarana to Araguacema in 12.5 hours. Alternatively, you can fly. The time zone difference when traveling from Canarana to Araguacema is 1 hour. In May, daily temperatures in Araguacema can reach 39°C, while at night they dip to 27°C. You will leave for Maraba on the 21st (Fri).

Things to do in Araguacema

Outdoors

Maraba, Brazil

— 1 night
Marabá is a municipality in the state of Pará, Brazil. Kick off your visit on the 21st (Fri): head outdoors with Praia do Tucunare and then examine the collection at Maraba Municipal Museum.

For reviews, other places to visit, where to stay, and tourist information, read our Maraba trip planner.

Traveling by car from Araguacema to Maraba takes 9 hours. Alternatively, you can fly. May in Maraba sees daily highs of 38°C and lows of 27°C at night. Cap off your sightseeing on the 22nd (Sat) early enough to travel to Sao Luis.

Things to do in Maraba

Museums · Outdoors
Highlights from your trip

Sao Luis, Brazil

— 2 nights

City of Tiles

Located on the island of Ilha Upaon-Acu, state capital Sao Luis represents the largest city in Maranhao.
Kick off your visit on the 22nd (Sat): don't miss a visit to Praca do Pescador.

To see reviews, ratings, and tourist information, you can read our Sao Luis vacation planner.

Explore your travel options from Maraba to Sao Luis with the Route module. Expect a daytime high around 36°C in May, and nighttime lows around 28°C. Wrap up your sightseeing on the 24th (Mon) early enough to fly to Fortaleza.

Things to do in Sao Luis

Historic Sites · Parks · Beaches · Outdoors

Fortaleza, Brazil

— 3 nights

Brazilian Miami

They don't call Fortaleza "Brazilian Miami" for nothing.
Start off your visit on the 24th (Mon): take in the architecture and atmosphere at Capela Sao Pedro. Get ready for a full day of sightseeing on the 25th (Tue): contemplate the long history of Igreja do Rosario, then enjoy the sand and surf at Praia de Cumbuco, and then enjoy the sand and surf at Praia do Futuro.

For more things to do, ratings, maps, and tourist information, you can read our Fortaleza online trip planner.

Traveling by flight from Sao Luis to Fortaleza takes 3 hours. Alternatively, you can drive; or take a bus. Expect a daytime high around 35°C in May, and nighttime lows around 28°C. Wrap up your sightseeing on the 27th (Thu) early enough to fly to Natal.

Things to do in Fortaleza

Parks · Beaches · Outdoors · Historic Sites

Side Trip

Natal, Brazil

— 2 nights

City of the Sun

The promise of sun, sand, and surf generates plenty of tourism in Natal.
On the 27th (Thu), kick back and relax at Morro do Careca and then stroll through Ponta Negra Beach. Get ready for a full day of sightseeing on the 28th (Fri): get great views at Reis Magos Fortress, see the interesting displays at Museu Camara Cascudo, stroll around Parque das Dunas, then pause for some serene contemplation at Igreja de Nossa Senhora dos Navegantes, and finally kick back and relax at Genipabu Beach.

To find photos, where to stay, reviews, and more tourist information, use the Natal day trip tool.

You can fly from Fortaleza to Natal in 2.5 hours. Alternatively, you can drive; or take a bus. In May in Natal, expect temperatures between 33°C during the day and 26°C at night. Finish your sightseeing early on the 29th (Sat) to allow enough time to fly to Porto de Galinhas.

Things to do in Natal

Parks · Beaches · Outdoors · Historic Sites

Porto de Galinhas, Brazil

— 2 nights

Hawaii of the Atlantic

You're in for a treat on your beach holiday to Porto de Galinha.
Start off your visit on the 29th (Sat): take in the exciting artwork at Casa Jerimum, tour the pleasant surroundings at Vila de Porto de Galinhas Beach, kick back and relax at Cupe beach, then tour the pleasant surroundings at Muro Alto Beach, then brush up on your knowledge of spirits at Cachacaria e Pimentaria Tio Gilson, and finally take in the exciting artwork at So Arte. On the 30th (Sun), you'll have a packed day of sightseeing: explore the galleries of Atelie Gilberto Carcara, stroll through Praia De Maracaipe, see the interesting displays at Museu das Tartarugas - ONG Ecoassociados, then take in the architecture and atmosphere at Capela Nossa Senhora do Desterro, and finally admire the striking features of Massangana Sugar Cane Mill.

To see ratings, maps, photos, and more tourist information, read Porto de Galinhas trip itinerary maker website.

Traveling by flight from Natal to Porto de Galinhas takes 2.5 hours. Alternatively, you can drive; or do a combination of bus and taxi. In May in Porto de Galinhas, expect temperatures between 34°C during the day and 27°C at night. Cap off your sightseeing on the 31st (Mon) early enough to catch the flight to Salvador.

Things to do in Porto de Galinhas

Parks · Beaches · Outdoors · Museums

Side Trips

Salvador, Brazil

— 1 night

Black Rome

Nowhere are the traditions of Brazil's African-background community as strong as in Salvador, the colorful, historical capital of Bahia state.
On the 31st (Mon), take an in-depth tour of Misericordia Museum and then tour the pleasant surroundings at Praia Farol da Barra.

To find traveler tips, where to stay, reviews, and more tourist information, read our Salvador trip app.

Fly from Porto de Galinhas to Salvador in 3.5 hours. Alternatively, you can drive; or take a bus. May in Salvador sees daily highs of 33°C and lows of 27°C at night. Finish up your sightseeing early on the 1st (Tue) so you can travel to Guanambi.

Things to do in Salvador

Parks · Beaches · Outdoors · Museums

Guanambi, Brazil

— 1 night
Start off your visit on the 1st (Tue): take an in-depth tour of Memorial Casa de Dona Dede.

For other places to visit, maps, and more tourist information, read our Guanambi day trip planning website.

Traveling by car from Salvador to Guanambi takes 9.5 hours. Alternatively, you can fly. You'll gain 1 hour traveling from Salvador to Guanambi due to the time zone difference. Wrap up your sightseeing on the 2nd (Wed) early enough to travel to Brasilia.

Things to do in Guanambi

Museums
Highlights from your trip

Brasilia, Brazil

— 2 nights

Capital of Hope

Although it lacks the cultural flair of Rio de Janeiro and the massive urban sprawl of Sao Paulo, Brasilia holds a fascinating place in the tapestry of Brazil.
Kick off your visit on the 2nd (Wed): pause for some photo ops at Mastro e Pavilhao Nacional.

To see reviews, ratings, traveler tips, and more tourist information, use the Brasilia trip planning website.

Use the Route module to find suitable travel options from Guanambi to Brasilia. The time zone difference when traveling from Guanambi to Brasilia is 1 hour. In June, daily temperatures in Brasilia can reach 30°C, while at night they dip to 16°C. Wrap up your sightseeing on the 4th (Fri) early enough to fly to Belo Horizonte.

Things to do in Brasilia

Historic Sites · Museums · Shopping

Belo Horizonte, Brazil

— 1 night

Garden City

Named for its spectacular mountain views, and known locally as the "Garden City," Belo Horizonte has historically fostered a connection with nature since its inauguration in 1897.
On the 4th (Fri), contemplate in the serene atmosphere at Igreja Sao Jose and then view the masterpieces at Palacio das Artes.

For reviews, more things to do, ratings, and tourist information, read Belo Horizonte road trip planning website.

Traveling by flight from Brasilia to Belo Horizonte takes 3 hours. Alternatively, you can drive; or take a bus. Expect a daytime high around 29°C in June, and nighttime lows around 19°C. On the 5th (Sat), you'll travel to Rio de Janeiro.

Things to do in Belo Horizonte

Museums · Shopping · Historic Sites

Rio de Janeiro, Brazil

— 3 nights

Marvelous City

Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
On the 5th (Sat), admire the masterpieces at Centro Cultural Banco do Brasil - CCBB Rio de Janeiro. Get ready for a full day of sightseeing on the 6th (Sun): make a trip to Escadaria Selaron, learn about all things military at Museu Historico do Exercito e Forte de Copacabana, then kick back and relax at Pedra do Arpoador, then tour the pleasant surroundings at Praia de Ipanema, and finally kick back and relax at Copacabana Beach.

To see traveler tips, photos, maps, and more tourist information, read our Rio de Janeiro trip itinerary maker app.

Getting from Belo Horizonte to Rio de Janeiro by flight takes about 3 hours. Other options: drive; or take a bus. June in Rio de Janeiro sees daily highs of 30°C and lows of 22°C at night. Finish your sightseeing early on the 8th (Tue) to allow enough time to fly to Sao Paulo.

Things to do in Rio de Janeiro

Parks · Beaches · Outdoors · Museums

Sao Paulo, Brazil

— 3 nights

Land of Drizzle

Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.
You'll explore and learn at Pinacoteca do Estado de Sao Paulo and Temple of Solomon. Popular historic sites such as Mosteiro De Sao Bento and São Paulo Cathedral are in your itinerary. Go for a jaunt from Sao Paulo to Guaruja to see Enseada Beach about 1h 35 min away. There's still lots to do: explore the world behind art at Museu de Arte de Sao Paulo Assis Chateaubriand - MASP, walk around Parque Ibirapuera, take a stroll through Liberdade, and get a taste of the local shopping with Paulista Avenue.

To find where to stay, more things to do, maps, and tourist information, go to the Sao Paulo day trip planner.

Traveling by flight from Rio de Janeiro to Sao Paulo takes 3 hours. Alternatively, you can drive; or take a bus. In June, Sao Paulo is slightly colder than Rio de Janeiro - with highs of 26°C and lows of 15°C. Cap off your sightseeing on the 11th (Fri) early enough to catch the flight to Curitiba.

Things to do in Sao Paulo

Parks · Museums · Historic Sites · Neighborhoods

Side Trip

Curitiba, Brazil

— 2 nights

Ecological Capital of Brazil

The word "Brazil" isn't often mentioned in the same breath as "excellent urban planning"--except in Curitiba.
Kick off your visit on the 11th (Fri): contemplate the long history of Ukranian Memorial, then explore the world behind art at Museu Oscar Niemeyer, and then wander the streets of Bairro de Santa Felicidade. Keep things going the next day: do a tasting at Familia Fardo Vinicola, then cruise along Estrada Da Graciosa, then pause for some serene contemplation at Paroquia Imaculado Coracao de Maria, and finally take in the spiritual surroundings of Santuario Tabor Magnificat.

To see reviews, photos, where to stay, and tourist information, read Curitiba trip planner.

Fly from Sao Paulo to Curitiba in 2.5 hours. Alternatively, you can drive; or take a bus. In June, Curitiba is slightly colder than Sao Paulo - with highs of 22°C and lows of 12°C. Finish your sightseeing early on the 13th (Sun) so you can travel to Puerto Iguazu.

Things to do in Curitiba

Historic Sites · Museums · Neighborhoods · Scenic Drive

Side Trip

Puerto Iguazu, Argentina

— 2 nights
The gateway to a national park inscribed on the World Heritage List, growing Puerto Iguazu sits on the confluence of two major rivers near the border with Paraguay and Brazil.
Start off your visit on the 13th (Sun): make a trip to Plaza San Martin and then stop by Puerto Iguazu. Get ready for a full day of sightseeing on the 14th (Mon): explore the striking landscape of Parque Nacional Iguazu, then look for gifts at Capriccio Alfajores & Gourmet, and then take in the architecture and atmosphere at Catedral Virgen del Carmen.

To find reviews, more things to do, and other tourist information, read our Puerto Iguazu trip planner.

Do a combination of flight and bus from Curitiba to Puerto Iguazu in 3.5 hours. Alternatively, you can drive; or do a combination of bus and car. In June in Puerto Iguazu, expect temperatures between 25°C during the day and 15°C at night. Wrap up your sightseeing on the 15th (Tue) early enough to drive to Asuncion.

Things to do in Puerto Iguazu

Nature · Parks · Neighborhoods · Shopping

Side Trip

Asuncion, Paraguay

— 3 nights

Mother of Cities

Paraguay's capital and economic center, Asuncion ranks among the youngest cities on the continent, with more than half of its residents under 30 years of age.
On the 16th (Wed), get outside with Aventura Xtrema, then head outdoors with Lago Ypacarai, then take in the exciting artwork at El Cantaro, Almacen de Arte, and finally head outdoors with Parque de la Salud. On your second day here, relax and rejuvenate at some of the top local wellness centers, admire the striking features of The National Pantheon of Heroes and Oratory of the Virgin Our Lady Saint Mary of the Asuncion, then contemplate the long history of Casa de la Independencia, and finally get a sense of history and politics at Palacio de López.

To find more things to do, other places to visit, where to stay, and more tourist information, you can read our Asuncion trip itinerary planning tool.

Traveling by car from Puerto Iguazu to Asuncion takes 5 hours. Alternatively, you can do a combination of ferry, bus, and taxi; or do a combination of ferry and bus. You'll gain 1 hour traveling from Puerto Iguazu to Asuncion due to the time zone difference. In June, daily temperatures in Asuncion can reach 26°C, while at night they dip to 15°C. Finish your sightseeing early on the 18th (Fri) so you can drive to Encarnacion.

Things to do in Asuncion

Outdoors · Museums · Historic Sites · Spas

Side Trip

Encarnacion, Paraguay

— 2 nights

Pearl of the South

Encarnacion offers a good selection of cultural and natural attractions.
Kick off your visit on the 18th (Fri): steep yourself in history at La Santisima Trinidad De Parana and then explore the ancient world of Ruinas de Jesús. On your second day here, enjoy the sand and surf at San Jose Beach and then get to know the fascinating history of Costanera de la Ciudad de Encarnacion Paraguay.

For traveler tips, maps, and other tourist information, refer to the Encarnacion tour planner.

Drive from Asuncion to Encarnacion in 6 hours. Alternatively, you can take a bus. In June, plan for daily highs up to 24°C, and evening lows to 13°C. Wrap up your sightseeing on the 20th (Sun) to allow time to travel to Salto.

Things to do in Encarnacion

Historic Sites · Parks · Beaches · Outdoors

Side Trip

Salto, Uruguay

— 2 nights
In a thriving citrus-growing region, Salto allows visitors to explore attractive riverfront areas and admire neatly preserved 19th-century architecture.
On the 20th (Sun), take an in-depth tour of Museo del Hombre y la Tecnologia and then relax and rejuvenate at Termas del Dayman. Here are some ideas for day two: do a tasting at Bodega Bertolini & Broglio, then contemplate in the serene atmosphere at Gruta del Padre Pio, then head outdoors with Hot Springs of Arapey, and finally explore the world behind art at Museo de Bellas Artes.

To see more things to do, maps, where to stay, and other tourist information, go to the Salto online route maker.

Drive from Encarnacion to Salto in 8 hours. Alternatively, you can do a combination of car and flight. The time zone difference moving from Paraguay Standard Time (PYT) to Uruguay Standard Time (UYT) is 1 hour. Traveling from Encarnacion in June, things will get slightly colder in Salto: highs are around 21°C and lows about 8°C. Wrap up your sightseeing on the 22nd (Tue) to allow time to take a bus to Montevideo.

Things to do in Salto

Museums · Historic Sites · Spas · Outdoors

Side Trip

Montevideo, Uruguay

— 3 nights
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
Museo Municipal de Bellas Artes Juan Manuel Blanes and 1972 Museum will appeal to museum buffs. Pocitos and Galeria de Arte Porton de San Pedro are good opportunities to explore the local culture. There's much more to do: make a trip to Plaza Independencia, admire the majestic nature at El Rosedal, kick back and relax at Playa Pocitos, and take in the architecture and atmosphere at Iglesia San Juan Bautista.

To see maps, more things to do, reviews, and more tourist information, read Montevideo sightseeing planner.

Traveling by bus from Salto to Montevideo takes 6.5 hours. Alternatively, you can drive. In June, daily temperatures in Montevideo can reach 19°C, while at night they dip to 7°C. Finish up your sightseeing early on the 25th (Fri) so you can go by car to Colonia del Sacramento.

Things to do in Montevideo

Neighborhoods · Outdoors · Museums · Parks

Colonia del Sacramento, Uruguay

— 2 nights
Sleepy cobbled streets lined with pastel-colored houses lead down to the water in Colonia del Sacramento.
Kick off your visit on the 25th (Fri): get engrossed in the history at Museo Portugues, steep yourself in history at Plaza de toros Real de San Carlos, make a trip to La Calle de los Suspiros, then visit a coastal fixture at Colonia del Sacramento Lighthouse, and finally wander the streets of Barrio Historico. Get ready for a full day of sightseeing on the next day: see the interesting displays at Museo Cars, browse for treasures at Antik Objetos con Alma, examine the collection at Granja Colonia, then wander the streets of Plaza Mayor, and finally view the masterpieces at Casa Carbajal Arte y Objetos.

To find traveler tips, photos, other places to visit, and tourist information, refer to the Colonia del Sacramento online vacation planner.

Drive from Montevideo to Colonia del Sacramento in 3 hours. Alternatively, you can take a bus. June in Colonia del Sacramento sees daily highs of 19°C and lows of 9°C at night. Cap off your sightseeing on the 27th (Sun) early enough to travel to Gualeguaychu.

Things to do in Colonia del Sacramento

Museums · Historic Sites · Neighborhoods · Shopping

Side Trips

Gualeguaychu, Argentina

— 1 night
Sitting on the left bank a Uruguay River tributary, Gualeguaychu was founded in 1783 and serves as a home to over 100,000 people.
Start off your visit on the 27th (Sun): stroll through Balneario Nandubaysal, test the waters at Termas del Gualeguaychu, and then take an in-depth tour of Casa de Haedo Museo.

For more things to do, reviews, where to stay, and tourist information, use the Gualeguaychu travel route planner.

You can drive from Colonia del Sacramento to Gualeguaychu in 3.5 hours. In June in Gualeguaychu, expect temperatures between 20°C during the day and 7°C at night. Finish your sightseeing early on the 28th (Mon) to allow enough time to drive back home.

Things to do in Gualeguaychu

Spas · Parks · Historic Sites · Beaches