60 days in South America & Mexico Itinerary

60 days in South America & Mexico Itinerary

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Route & dates

60 days in South America & Mexico Itinerary

Start: Tandil, Argentina
Drive:  4​h
1
Buenos Aires, Argentina
— 4 nights
Fly + Drive:  3​h
2
Ciudad Del Este, Paraguay
— 1 night
+2
bus + taxi + Fly:  11​h 30​min
3
Sucre, Bolivia
— 3 nights
Fly + taxi:  5​h 15​min
4
Uyuni, Bolivia
— 2 nights
taxi + Fly:  3​h 45​min
5
La Paz, Bolivia
— 5 nights
bus + Fly:  1​h 45​min
6
Cusco, Peru
— 6 nights
+2
bus + foot + train:  3​h 15​min
7
Machu Picchu, Peru
— 5 nights
Drive + Fly:  12​h
8
Lima, Peru
— 2 nights
Fly:  7​h
9
Mexico City, Mexico
— 3 nights
Fly:  3​h 15​min
10
Puerto Vallarta, Mexico
— 6 nights
Fly:  7​h
11
Playa del Carmen, Mexico
— 6 nights
+2
bus + foot + Fly:  19​h 45​min
12
San Carlos de Bariloche, Argentina
— 5 nights
Fly:  6​h 45​min
13
Mendoza, Argentina
— 4 nights
+2
Fly + taxi + bus:  6​h
End: Tandil, Argentina

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
You'll explore the less-touristy side of things at Catedral Metropolitana and Puente de la Mujer. There's much more to do: don't miss a visit to Recoleta Cemetery, explore the engaging exhibits at Museo de los Ninos, admire the natural beauty at Parque 3 de Febrero, and get a sense of history and politics at Casa Rosada.

For where to stay, other places to visit, more things to do, and tourist information, refer to the Buenos Aires journey planning tool .

Tandil to Buenos Aires is an approximately 4-hour car ride. You can also take a bus; or do a combination of bus and flight. Expect a bit warmer evenings in Buenos Aires when traveling from Tandil in July, with lows around 10°C. Finish your sightseeing early on the 18th (Thu) to allow enough time to travel to Ciudad Del Este.

Things to do in Buenos Aires

Neighborhoods Historic Sites Shopping
Highlights from your plan
Puerto Madero ©
Puerto Madero
Parque 3 de Febrero ©
Parque 3 de Febrero
Cemiterio de Recoleta ©
Cemiterio de Recoleta

1
night
Ciudad Del Este, Paraguay

Ciudad Del Este ©
The commercial center of eastern Paraguay, busy Ciudad Del Este serves primarily as a shopping destination for Argentines and Brazilians.
Start off your visit on the 19th (Fri): admire the sheer force of Saltos del Monday and then look for all kinds of wild species at Parque Aventura Monday.

To find reviews, photos, other places to visit, and tourist information, you can read our Ciudad Del Este trip itinerary planner.

You can do a combination of flight and car from Buenos Aires to Ciudad Del Este in 3 hours. Alternatively, you can do a combination of bus and car; or drive. Expect a bit warmer weather when traveling from Buenos Aires in July: highs in Ciudad Del Este hover around 26°C, while lows dip to 13°C. Cap off your sightseeing on the 19th (Fri) early enough to travel to Sucre.

Things to do in Ciudad Del Este

Parks Wildlife Nature

Side Trip

Presidente Franco
Highlights from your plan
Parque Aventura Monday ©
Parque Aventura Monday
Saltos del Monday ©
Saltos del Monday

3
nights
Sucre, Bolivia

Sucre ©
The constitutional capital of Bolivia, Sucre has a well-preserved historic center, with many buildings dating back to the city's founding in the 16th century.
You'll discover tucked-away gems like La Maja and Climbing Tours. And it doesn't end there: make a trip to Plaza 25 de Mayo, see the interesting displays at Museo del Tesoro, stop by Inca Pallay Shop, and get engrossed in the history at House of Liberty Museum - Casa de la Libertad.

To find other places to visit, reviews, traveler tips, and more tourist information, read Sucre trip itinerary maker site .

You can do a combination of bus and flight from Ciudad Del Este to Sucre in 11.5 hours. Alternatively, you can do a combination of car and flight; or drive. The time zone difference moving from Brasilia Time to Bolivia Time is minus 1 hour. Traveling from Ciudad Del Este in July, expect little chillier with lows of 4°C in Sucre. Finish your sightseeing early on the 23rd (Tue) to allow enough time to travel to Uyuni.

Things to do in Sucre

Historic Sites Museums Outdoors
Highlights from your plan
General Cemetery ©
General Cemetery
Parque Simon Bolivar ©
Parque Simon Bolivar
Centro Cultural Masis ©
Centro Cultural Masis

2
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
You'll discover tucked-away gems like Isla Incahuasi and Necropolis & Museum Kawsay Wasy. There's still lots to do: explore the striking landscape at Salar de Uyuni and contemplate the geological forces at Tunupa Volcano.

For other places to visit, traveler tips, more things to do, and tourist information, use the Uyuni trip builder tool .

You can do a combination of flight and taxi from Sucre to Uyuni in 5.5 hours. Alternatively, you can drive; or do a combination of bus and taxi. Traveling from Sucre in July, expect nights in Uyuni to be about the same, around 3°C, while days are cooler, around 4°C. Cap off your sightseeing on the 26th (Fri) early enough to travel to La Paz.

Things to do in Uyuni

Parks Nature Museums
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi
Tunupa Volcano ©
Tunupa Volcano

5
nights
La Paz, Bolivia

Take a moment to catch your breath as you commence your holiday in La Paz.
Explore hidden gems such as Mi Teleferico and Walking tours. Spend the 28th (Sun) exploring the striking scenery along WMDR Yungas Road. Spend the 29th (Mon) exploring nature at Cotapata National Park. Next up on the itinerary: get outside with Outdoor Activities, hike along Thaki Voyage, tee off at Golf Tours Bolivia-Day Tours, and take in breathtaking views at Palca Canyon.

For other places to visit, maps, ratings, and tourist information, read La Paz trip builder site .

Traveling by combination of taxi and flight from Uyuni to La Paz takes 4 hours. Alternatively, you can drive; or do a combination of taxi and bus. Traveling from Uyuni in July, expect nights in La Paz to be slightly colder, around -4°C, while days are somewhat warmer, around 17°C. Finish your sightseeing early on the 31st (Wed) so you can travel to Cusco.

Things to do in La Paz

Outdoors Parks Nature
Highlights from your plan
Adrenaline & Extreme Tours
Mi Teleferico ©
Mi Teleferico
WMDR Yungas Road ©
WMDR Yungas Road

6
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
You'll explore the less-touristy side of things at Sacred Valley of the Incas and Tipon. Take a break from Cusco with a short trip to Pisac in Pisac, about 52 minutes away. On the 3rd (Sat), spend a fun day on foot with Walking tours. Treat yourself to a day of pampering on the 6th (Tue) at some of the best spas. There's much more to do: delve into the distant past at Sacsayhuaman, look for all kinds of wild species at Santuario Animal de Cochahuasi, let the river carry you with a rafting and tubing tour, and wander the streets of San Blas.

For other places to visit, traveler tips, maps, and tourist information, read our Cusco vacation app .

Traveling by combination of bus and flight from La Paz to Cusco takes 2 hours. Alternatively, you can drive; or take a bus. Traveling from La Paz to Cusco, you'll gain 1 hour due to the time zone difference. In July, Cusco is a bit warmer than La Paz - with highs of 24°C and lows of 1°C. Finish your sightseeing early on the 6th (Tue) so you can travel to Machu Picchu.

Things to do in Cusco

Historic Sites Tours Spas

Side Trips

Pisac, Sacred Valley of the Incas
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Pisac ©
Pisac
Sacred Valley of the Incas ©
Sacred Valley of the Incas

5
nights
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Step off the beaten path and head to Intipuncu and Catarata Perolniyoc. Get out of town with these interesting Machu Picchu side-trips: Ollantaytambo (Qosqo Ayllu, Perolniyoq Waterfall, & more) and Banos Termales de Cocalmayo (in Santa Teresa). There's still lots to do: steep yourself in history at Santuario Historico de Machu Picchu, stop by Mapi Art, delve into the distant past at Winay Wayna, and take in nature's colorful creations at Los Jardines de Mandor.

To find more things to do, reviews, and more tourist information, read our Machu Picchu trip maker website .

You can do a combination of bus and train from Cusco to Machu Picchu in 3.5 hours. Other options are to take a train; or drive. Cap off your sightseeing on the 11th (Sun) early enough to travel to Lima.

Things to do in Machu Picchu

Parks Nature Historic Sites

Side Trips

Ollantaytambo, Banos Termales de Cocalmayo, Catarata Perolniyoc
Highlights from your plan
Santuario Historico de Machu Picchu ©
Intipuncu ©
Intipuncu
Winay Wayna ©
Winay Wayna

2
nights
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Discover out-of-the-way places like Huaca Pucllana and Barranco. There's lots more to do: take in the architecture and atmosphere at Iglesia y Convento de San Francisco, take a stroll through Miraflores, take an in-depth tour of Museo Larco, and admire the local landmark of Plaza de Armas (Plaza Mayor).

For photos, ratings, reviews, and other tourist information, you can read our Lima trip itinerary website .

Getting from Machu Picchu to Lima by combination of car and flight takes about 12 hours. Other options: drive; or do a combination of taxi and bus. August in Lima sees daily highs of 22°C and lows of 18°C at night. Finish up your sightseeing early on the 14th (Wed) so you can travel to Mexico City.

Things to do in Lima

Historic Sites Neighborhoods Shopping
Highlights from your plan
Huaca Pucllana ©
Huaca Pucllana
Miraflores Boardwalk ©
Miraflores Boardwalk
Barranco ©
Barranco

3
nights
Mexico City, Mexico

Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Discover out-of-the-way places like Paseo de la Reforma and Coyoacan. There's much more to do: examine the collection at National Museum of Anthropology, explore the historical opulence of Chapultepec Castle, delve into the distant past at Museo del Templo Mayor, and delve into the lush surroundings at Chapultepec Park.

To see more things to do, where to stay, and more tourist information, you can read our Mexico City online vacation maker .

You can fly from Lima to Mexico City in 7 hours. The time zone difference moving from Peru Time (PET) to Central Standard Time (CST) is minus 1 hour. Traveling from Lima in August, you will find days in Mexico City are a bit warmer (28°C), and nights are about the same (16°C). Wrap up your sightseeing on the 18th (Sun) to allow time to travel to Puerto Vallarta.

Things to do in Mexico City

Historic Sites Museums Tours

Side Trip

Zona Arqueológica de Teotihuacan Estacionamiento Puerta 5
Highlights from your plan
Food Tours
Chapultepec Castle ©
Chapultepec Castle
Paseo de la Reforma ©
Paseo de la Reforma

6
nights
Puerto Vallarta, Mexico

Boasting a coastline made for perfectly framed photographs of romantic sunsets, Puerto Vallarta continuously ranks among the world's top tourist resorts.
Explore hidden gems such as Marietas Islands and Dolphin & Whale Watching. Change things up with these side-trips from Puerto Vallarta: Nuevo Vallarta Beach (in Nuevo Vallarta), Vallarta Botanical Gardens (in Cabo Corrientes) and A Broken Art (in Bucerias). There's much more to do: appreciate the extensive heritage of Zona Romantica, get close to the beloved marine mammals with a swim-with-the-dolphins experience, see some colorful creatures with a scuba or snorkeling tour, and relax and rejuvenate at some of the top local wellness centers.

To find reviews, other places to visit, ratings, and more tourist information, go to the Puerto Vallarta road trip app .

Traveling by flight from Mexico City to Puerto Vallarta takes 3.5 hours. Alternatively, you can do a combination of bus and flight; or drive. Traveling from Mexico City in August, things will get a bit warmer in Puerto Vallarta: highs are around 37°C and lows about 28°C. Finish up your sightseeing early on the 24th (Sat) so you can travel to Playa del Carmen.

Things to do in Puerto Vallarta

Tours Outdoors Parks

Side Trips

Nuevo Vallarta, A Broken Art, Marietas Islands, Vallarta Botanical Gardens
Highlights from your plan
Food Tours
Nuevo Vallarta Beach ©
Nuevo Vallarta Beach
El Centro ©
El Centro

6
nights
Playa del Carmen, Mexico

The tourist hub of the popular Mayan Riviera, upscale Playa del Carmen remains the jewel of Mexico's Caribbean coastline.
Step off the beaten path and head to Grand Cenote and Cenote Chaak Tun. Explore the numerous day-trip ideas around Playa del Carmen: Tulum (Scuba & Snorkeling, Plastic Flamingo, & more) and Palancar Reef (in Cozumel). There's much more to do: soothe aching muscles at some of the top local wellness centers, take in the architecture and atmosphere at Nuestra Senora del Carmen Catholic Church, explore the world behind art at 3D Museum of Wonders, and find something for the whole family at Xcaret Park.

For reviews, photos, and tourist information, refer to the Playa del Carmen trip planner .

Fly from Puerto Vallarta to Playa del Carmen in 7 hours. Alternatively, you can drive; or take a bus. The time zone difference moving from Central Standard Time (CST) to Eastern Standard Time (EST) is 1 hour. In August in Playa del Carmen, expect temperatures between 35°C during the day and 26°C at night. On the 31st (Sat), wrap the sightseeing up by early afternoon so you can travel to San Carlos de Bariloche.

Things to do in Playa del Carmen

Outdoors Parks Tours

Side Trips

Tulum, Palancar Reef
Highlights from your plan
Climbing Tours
Scuba & Snorkeling
Palancar Reef ©
Palancar Reef

5
nights
San Carlos de Bariloche, Argentina

San Carlos de Bariloche ©
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
Explore hidden gems such as Piedras Blancas and Parque Nacional Nahuel Huapi. On the 5th (Thu), spend an exhilarating day on the slopes at Catedral Alta Patagonis. And it doesn't end there: head outdoors with Outdoor Activities, test your team's savvy at popular escape rooms, stop by Chocolaterie VanWynsberghe, and walk around Parque Nahuelito.

To see more things to do and more tourist information, refer to the San Carlos de Bariloche day trip planning site .

You can do a combination of bus and flight from Playa del Carmen to San Carlos de Bariloche in 20 hours. Another option is to do a combination of ferry and flight. You'll lose 2 hours traveling from Playa del Carmen to San Carlos de Bariloche due to the time zone difference. Prepare for colder weather when traveling from Playa del Carmen in September: high temperatures in San Carlos de Bariloche hover around 13°C and lows are around 0°C. Wrap up your sightseeing on the 6th (Fri) early enough to travel to Mendoza.

Things to do in San Carlos de Bariloche

Parks Outdoors Winter Sports
Highlights from your plan
Ventisquero Negro ©
Ventisquero Negro
Catedral Alta Patagonis
Catedral Alta Patagonis
Parque Nacional Nahuel Huapi ©
Parque Nacional Nahuel Huapi

4
nights
Mendoza, Argentina

Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Discover out-of-the-way places like Canon del Atuel and Potrerillos Dam. When in Mendoza, make a side trip to see Casa El Enemigo in Maipu, approximately 38 minutes away. Dedicate the 7th (Sat) to wine at some of the top wineries in the area. On the 10th (Tue), give your taste buds a day to remember with a local gastronomic tour. Next up on the itinerary: take some stellar pictures from Cerro de la Gloria, learn about winemaking at Bodega Catena Zapata, and stroll around Parque General San Martin.

To find more things to do, other places to visit, where to stay, and more tourist information, use the Mendoza online day trip planner .

Fly from San Carlos de Bariloche to Mendoza in 7 hours. Alternatively, you can drive; or take a bus. Plan for a bit warmer temperatures traveling from San Carlos de Bariloche in September, with highs in Mendoza at 25°C and lows at 9°C. Finish your sightseeing early on the 11th (Wed) so you can travel back home.

Things to do in Mendoza

Tours Wineries Parks

Side Trips

Canon del Atuel, Casa El Enemigo
Highlights from your plan
Food Tours
Canon del Atuel ©
Canon del Atuel
Wine Tours & Tastings

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