60 days in South America & Central America Itinerary

60 days in South America & Central America Itinerary

Created using Inspirock vacation planner

Make it your trip
1
Arequipa, Peru
— 6 nights
Fly
2
Lima, Peru
— 6 nights
Fly
3
Iquitos, Peru
— 4 nights
Fly
4
Guayaquil, Ecuador
— 5 nights
Fly
5
Quito, Ecuador
— 7 nights
Fly
6
Cali, Colombia
— 5 nights
Fly
7
Bogota, Colombia
— 6 nights
Fly
8
Medellin, Colombia
— 6 nights
Fly
9
Panama City, Panama
— 6 nights
Fly
10
Cartagena, Colombia
— 7 nights

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Arequipa, Peru

— 6 nights

White City

In an area dominated three imposing volcanoes, Arequipa vacations allow visitors to admire well-preserved colonial architecture in a dramatic setting.
Arequipa is known for museums, historic sites, and nature. Your plan includes some of its best attractions: examine the collection at Santa Catalina Monastery, admire the landmark architecture of Casa del Moral, make a trip to Plaza de Armas, and take an in-depth tour of Museo Santuarios Andinos.

To see ratings, where to stay, more things to do, and more tourist information, go to the Arequipa trip planner.

If you are flying in from Brazil, the closest major aiport is Rodríguez Ballón International Airport. In August, plan for daily highs up to 24°C, and evening lows to 9°C. Finish your sightseeing early on the 5th (Sun) so you can fly to Lima.

Things to do in Arequipa

Tours · Museums · Historic Sites · Parks

Lima, Peru

— 6 nights

City of the Kings

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Lima is known for museums, parks, and historic sites. Your plan includes some of its best attractions: get engrossed in the history at Museo Larco, visit Barranco, explore the ancient world of Huaca Pucllana, and wander the streets of Miraflores.

To see where to stay, other places to visit, more things to do, and more tourist information, use the Lima travel planner.

You can fly from Arequipa to Lima in 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from Arequipa in September, Lima is somewhat warmer at night with lows of 18°C. Cap off your sightseeing on the 11th (Sat) early enough to catch the flight to Iquitos.

Things to do in Lima

Historic Sites · Tours · Museums · Parks

Iquitos, Peru

— 4 nights

Capital of the Peruvian Amazon

The largest city in the Peruvian Amazon and the world's largest metropolis unreachable by road, Iquitos represents a major starting point for river and rainforest adventures.
Step out of Iquitos to go to Rio Momon and see Momon River, which is approximately 52 minutes away. Next up on the itinerary: explore the activities along Amazon River, examine the collection at Museum of Indigenous Amazonian Cultures, soothe aching muscles at El Purguero, and don't miss a visit to Plaza de Armas de Iquitos.

For where to stay, reviews, maps, and more tourist information, you can read our Iquitos trip site.

Getting from Lima to Iquitos by flight takes about 4 hours. Other options: do a combination of bus, car, and ferry. Traveling from Lima in September, expect nights in Iquitos to be a bit warmer, around 26°C, while days are much hotter, around 38°C. Wrap up your sightseeing on the 15th (Wed) to allow time to fly to Guayaquil.

Things to do in Iquitos

Parks · Nature · Outdoors · Tours

Side Trip

Guayaquil, Ecuador

— 5 nights

Pearl of the Pacific

Hills dotted with colorful houses and waterfront promenades typify Guayaquil, Ecuador's largest city and commercial center.
Guayaquil is known for historic sites, parks, and shopping. Your plan includes some of its best attractions: stop by Las Penas, admire the masterpieces at Museum of Anthropology and Contemporary Art, take in the architecture and atmosphere at Iglesia de La Merced, and get a taste of life in the country at Hacienda La Danesa.

To see traveler tips, maps, reviews, and other tourist information, read our Guayaquil road trip planning website.

Traveling by flight from Iquitos to Guayaquil takes 9 hours. Alternatively, you can do a combination of car, ferry, and bus; or do a combination of ferry and bus. Expect a daytime high around 36°C in September, and nighttime lows around 25°C. Finish up your sightseeing early on the 21st (Tue) so you can catch the flight to Quito.

Things to do in Guayaquil

Historic Sites · Parks · Neighborhoods · Wildlife

Quito, Ecuador

— 7 nights

Light of America

High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
You'll find plenty of places to visit near Quito: Pichincha (in Puerto Quito), Cuicocha (in Cotacachi) and Pululahua Geobotanical Reserve (in Calacali). Next up on the itinerary: take an in-depth tour of Museo Templo del Sol Pintor Ortega Maila, let your taste buds guide you at a local gastronomic tour, deepen your understanding at La Ronda, and contemplate in the serene atmosphere at Basilica del Voto Nacional.

To find traveler tips, more things to do, and other tourist information, use the Quito travel planning app.

Traveling by flight from Guayaquil to Quito takes 2.5 hours. Alternatively, you can drive; or take a bus. Traveling from Guayaquil in September, expect Quito to be slightly colder, temps between 26°C and 15°C. Finish your sightseeing early on the 28th (Tue) so you can fly to Cali.

Things to do in Quito

Museums · Parks · Historic Sites · Nature

Side Trips

Cali, Colombia

— 5 nights

Salsa Capital of the World

Learning how to salsa may be the most popular thing to do in Cali, but this giant city in southwestern Colombia represents more than just the "Salsa Capital of the World." Home to over 2 million people, thriving Cali serves as a major commercial and industrial center in South America, boasting the fastest-growing economy in Colombia.
Cali is known for zoos & aquariums, historic sites, and museums. Your plan includes some of its best attractions: see the interesting displays at Museo Aereo Fenix, learn about wildlife with up-close encounters at Zoologico de Cali, relax and rejuvenate at some of the top local wellness centers, and admire the striking features of El Gato Del Rio( Gato De Tejada).

For ratings, where to stay, traveler tips, and other tourist information, you can read our Cali road trip planner.

Traveling by flight from Quito to Cali takes 6 hours. Alternatively, you can take a bus; or drive. Prepare for a bit warmer weather when traveling from Quito in September: high temperatures in Cali hover around 37°C and lows are around 22°C. Finish up your sightseeing early on the 3rd (Sun) so you can catch the flight to Bogota.

Things to do in Cali

Tours · Wildlife · Outdoors · Historic Sites

Bogota, Colombia

— 6 nights

Athens of South America

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Change things up with these side-trips from Bogota: Centro de Memoria El Cuartico (in Valledupar) and Zipaquira (Casa Museo Quevedo Zornoza, Catedral de Sal de Zipaquira, &more). The adventure continues: examine the collection at Gold Museum (Museo del Oro), savor the flavors at Food & Drink, explore the world behind art at Museo Botero del Banco de la Republica, and take in the local highlights with Walking tours.

To see reviews, more things to do, photos, and other tourist information, refer to the Bogota road trip planning website.

Getting from Cali to Bogota by flight takes about 3 hours. Other options: drive; or do a combination of bus and taxi. Plan for slightly colder temperatures traveling from Cali in October, with highs in Bogota at 22°C and lows at 9°C. Wrap up your sightseeing on the 9th (Sat) to allow time to fly to Medellin.

Things to do in Bogota

Museums · Tours · Historic Sites · Nature

Side Trips

Medellin, Colombia

— 6 nights

City of the Eternal Spring

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Go for a jaunt from Medellin to Caldas to see Catedral Nuestra Señora de las Mercedes about 34 minutes away. And it doesn't end there: take in the local highlights with Walking tours, observe the fascinating underwater world at Parque Explora, get engrossed in the history at Museo de Antioquia, and glide through the air with a parasailing or paragliding tour.

To see more things to do, reviews, ratings, and more tourist information, read our Medellin trip app.

Traveling by flight from Bogota to Medellin takes 2.5 hours. Alternatively, you can drive; or take a bus. Traveling from Bogota in October, things will get a bit warmer in Medellin: highs are around 32°C and lows about 20°C. Finish your sightseeing early on the 15th (Fri) to allow enough time to fly to Panama City.

Things to do in Medellin

Parks · Tours · Wildlife · Outdoors

Side Trips

Panama City, Panama

— 6 nights

Dubai of Latin America

Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Panama City is known for historic sites, shopping, and museums. Your plan includes some of its best attractions: make a trip to Panama Canal, see the interesting displays at Biomuseo, explore the wealth of natural beauty at Metropolitan National Park, and stop by Cinta Costera.

For traveler tips, reviews, more things to do, and more tourist information, read our Panama City online trip itinerary planner.

You can fly from Medellin to Panama City in 4.5 hours. Other options are to do a combination of bus, ferry, and taxi; or do a combination of bus and ferry. In October, Panama City is somewhat warmer than Medellin - with highs of 36°C and lows of 28°C. Finish your sightseeing early on the 21st (Thu) so you can fly to Cartagena.

Things to do in Panama City

Historic Sites · Parks · Neighborhoods · Nature

Cartagena, Colombia

— 7 nights

City of Heroes

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Change things up with these side-trips from Cartagena: Playa Blanca (in Isla Baru) and Oceanario (in Islas de Rosario). Next up on the itinerary: explore the historical opulence of Castillo de San Felipe de Barajas, get impressive views of Volcan de Lodo El Totumo (Mud Volcano), make a trip to Plaza Santo Domingo, and contemplate in the serene atmosphere at Convent of Santa Cruz de la Popa.

Find out how to plan Cartagena trip without stress by asking Inspirock to help create an itinerary.

Traveling by flight from Panama City to Cartagena takes 4.5 hours. In October in Cartagena, expect temperatures between 38°C during the day and 30°C at night.

Things to do in Cartagena

Historic Sites · Parks · Tours · Outdoors

Side Trips