60 days in Colombia, Argentina & Panama Itinerary

60 days in Colombia, Argentina & Panama Itinerary

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Route & dates

60 days in Colombia, Argentina & Panama Itinerary

Start: Orlando, United States
Fly:  7​h
1
Cartagena, Colombia
— 4 nights
Fly:  4​h
2
Medellin, Colombia
— 5 nights
Fly:  9​h 30​min
3
Salta, Argentina
— 3 nights
Fly:  2​h 15​min
4
Iguazu National Park, Argentina
— 2 nights
Fly:  3​h 30​min
5
Buenos Aires, Argentina
— 6 nights
Fly:  5​h 15​min
6
Ushuaia, Argentina
— 4 nights
Fly:  2​h
7
El Calafate, Argentina
— 3 nights
bus:  2​h
8
Los Glaciares National Park, Argentina
— 2 nights
Fly:  5​h
9
San Carlos de Bariloche, Argentina
— 5 nights
Fly:  4​h 15​min
10
Cordoba, Argentina
— 3 nights
Fly:  2​h
11
Mendoza, Argentina
— 5 nights
Fly:  8​h
12
Bogota, Colombia
— 5 nights
Fly:  2​h 15​min
13
Panama City, Panama
— 5 nights
Fly:  2​h 30​min
14
San Andres Island, Colombia
— 6 nights
Fly:  8​h 15​min
End: Orlando, United States

4
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Get a sense of the local culture at Bairro Getsemani and Templo de Santo Domingo. You'll explore the less-touristy side of things at Aviario Nacional de Colombia and Centro de Convenciones Cartagena de Indias. There's still lots to do: don't miss a visit to Plaza de La Trinidad, see the interesting displays at Casa Museo Rafael Nunez, ponder the world of politics at Alcaldia Mayor, and step into the grandiose world of Castillo de San Felipe de Barajas.

To find more things to do, traveler tips, other places to visit, and tourist information, read Cartagena route planner.

Orlando, USA to Cartagena is an approximately 7-hour flight. You can also do a combination of flight and bus; or do a combination of bus and flight. Expect somewhat warmer evenings in Cartagena when traveling from Orlando in June, with lows around 79°F. Wrap up your sightseeing on the 5th (Fri) to allow time to travel to Medellin.

Things to do in Cartagena

Historic Sites Neighborhoods Wildlife

Side Trip

Aviario Nacional de Colombia
Highlights from your plan
Castillo de San Felipe de Barajas ©
Bairro Getsemani ©
Bairro Getsemani
Templo de Santo Domingo ©
Templo de Santo Domingo

5
nights
Medellin, Colombia

Medellin ©
Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Satisfy your inner culture vulture at Museo de Arte Moderno de Medellin and H by HDC. Step off the beaten path and head to Parque Arvi and 2000m Descent and more. And it doesn't end there: buy something for everyone on your list at El Tesoro Parque Comercial, examine the collection at Museo Casa de la Memoria, indulge in some personalized pampering at some of the best spas, and take in the architecture and atmosphere at Iglesia San José del Poblado.

To find photos, where to stay, more things to do, and tourist information, read our Medellin trip itinerary planner .

Traveling by flight from Cartagena to Medellin takes 4 hours. Alternatively, you can do a combination of bus and flight; or drive. In June, Medellin is a bit cooler than Cartagena - with highs of 83°F and lows of 64°F. Wrap up your sightseeing on the 10th (Wed) early enough to travel to Salta.

Things to do in Medellin

Shopping Wildlife Parks

Side Trip

Mayorca Mega Plaza
Highlights from your plan
Mayorca Mega Plaza ©
Mayorca Mega Plaza
Museo de Arte Moderno de Medellin ©
Museo de Arte Moderno de Medellin
Parque Arvi ©
Parque Arvi

3
nights
Salta, Argentina

Salta ©
Salta boasts a vibrant social life and array of informative museums appealing to visitors looking for a memorable cultural experience.
For shopping fun, head to Vincul Arte or Mercado Artesanal Tradicional. Museum-lovers will get to explore Museo Guemes and MAAM - Museo de Arqueologia de Alta Montana de Salta. Get out of town with these interesting Salta side-trips: San Salvador de Jujuy (Catedral de San Salvador de Jujuy, Iglesia de San Francisco y Museo de Arte Sacro, & more). There's much more to do: admire the masterpieces at Museo Pajcha Arte Etnico, take in the architecture and atmosphere at Iglesia Nuestra Senora de La Candelaria de La Vina, wander the streets of La Caldera, and take in the dramatic natural features at Alemania.

To find traveler tips, reviews, ratings, and other tourist information, refer to the Salta road trip app .

Traveling by flight from Medellin to Salta takes 9.5 hours. Alternatively, you can do a combination of bus and car; or drive. Traveling from Medellin to Salta, you'll lose 2 hours due to the time zone difference. Traveling from Medellin in June, expect nights in Salta to be much colder, around 41°F, while days are little chillier, around 66°F. Cap off your sightseeing on the 14th (Sun) early enough to travel to Iguazu National Park.

Things to do in Salta

Museums Neighborhoods Historic Sites

Side Trip

San Salvador de Jujuy
Highlights from your plan
Museo Guemes ©
Museo Guemes
Museo Pajcha Arte Etnico ©
Museo Pajcha Arte Etnico
Catedral de San Salvador de Jujuy ©
Catedral de San Salvador de Jujuy

2
nights
Iguazu National Park, Argentina

Iguazu National Park ©
Iguazu National Park contains 672 sq km (259 sq mi) of fertile subtropical forests, but its main attraction is the majestic Iguazu Falls.
Start off your visit on the 15th (Mon): go deep underground at Wanda Mines and then explore the wealth of natural beauty at Provincial Urugua-i Park. On the next day, admire the sheer force of Salto Bernabe Mendez.

Ask Inspirock to suggest an itinerary and make planning a trip to Iguazu National Park fast, fun, and easy.

Traveling by flight from Salta to Iguazu National Park takes 2.5 hours. Alternatively, you can drive; or take a bus. Traveling from Salta in June, expect somewhat warmer with lows of 53°F in Iguazu National Park. Finish your sightseeing early on the 16th (Tue) so you can travel to Buenos Aires.

Things to do in Iguazu National Park

Wildlife Parks Nature

Side Trips

Provincial Urugua-i Park, Wanda Mines
Highlights from your plan
Provincial Urugua-i Park ©
Provincial Urugua-i Park
Salto Bernabe Mendez ©
Salto Bernabe Mendez
Wanda Mines ©
Wanda Mines

6
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Head to Puerto Madero and El Ateneo Grand Splendidfor plenty of shopping. Museo de La Plata and Estancia Santa Susana are good opportunities to explore the local culture. Get out of town with these interesting Buenos Aires side-trips: Reserva Natural Urbana (in Castelar), Basilica de Lujan (in Lujan) and Planetario Ciudad de La Plata (in La Plata). There's much more to do: see the interesting displays at Museo Del Bicentenario, look for all kinds of wild species at Complejo Ecologico Naturaleza Viva, explore the galleries of Basilica de Nuestra Senora Del Pilar, and pause for some serene contemplation at Basilica del Santisimo Sacramento.

For reviews, other places to visit, where to stay, and tourist information, read our Buenos Aires trip itinerary app .

Traveling by flight from Iguazu National Park to Buenos Aires takes 3.5 hours. Alternatively, you can drive; or take a bus. When traveling from Iguazu National Park in June, plan for little chillier days and about the same nights in Buenos Aires: temperatures range from 60°F by day to 49°F at night. Cap off your sightseeing on the 22nd (Mon) early enough to travel to Ushuaia.

Things to do in Buenos Aires

Wildlife Parks Museums

Side Trips

La Plata, Florencio Varela, Basilica de Lujan, Reserva Natural Urbana, Estancia Santa Susana
Highlights from your plan
Puerto Madero ©
Puerto Madero
Estancia Santa Susana ©
Estancia Santa Susana
Museo de La Plata ©
Museo de La Plata

4
nights
Ushuaia, Argentina

Often called the "End of the World" because of its position on the southernmost tip of South America, the expanding city of Ushuaia serves as both a busy commercial port and attractive tourist hub.
Museum-lovers will appreciate Museo Maritimo y del Presidio de Ushuaia and Feria artesanal Ushuaia. Discover out-of-the-way places like Helicopter Tours and Playa Larga. And it doesn't end there: stroll through Glaciar Martial, examine the collection at Antigua Casa de Gobierno, push the limits with an extreme tour, and learn more about the world around you at Acatushun Museum.

To see where to stay, ratings, reviews, and tourist information, you can read our Ushuaia planner .

Fly from Buenos Aires to Ushuaia in 5.5 hours. Alternatively, you can do a combination of car and ferry; or take a bus. While traveling from Buenos Aires, expect cooler days and a bit cooler nights in Ushuaia, ranging from highs of 40°F to lows of 33°F. Wrap up your sightseeing on the 26th (Fri) to allow time to travel to El Calafate.

Things to do in Ushuaia

Outdoors Tours Parks

Side Trip

Glaciar Martial
Highlights from your plan
Adrenaline & Extreme Tours
Playa Larga ©
Playa Larga

3
nights
El Calafate, Argentina

El Calafate ©
El Calafate tourism thrives mostly thanks to the city's proximity to a World Heritage-listed national park, famed for containing over 40 large glaciers.
Let the collections at El Calafate Historical Interpretation Center and Museo Regional Municipal de El Calafate capture your imagination. Satisfy your inner culture vulture at Santa Teresita del Nino Jesus and Avenida Libertador. Next up on the itinerary: make a trip to Parque Nacional Los Glaciares, look for all kinds of wild species at Patagonia Profunda - Safari Experience, and stop by La Aldea de los Gnomos.

To find more things to do, traveler tips, where to stay, and more tourist information, read El Calafate attractions planner .

You can fly from Ushuaia to El Calafate in 2 hours. Alternatively, you can do a combination of car and ferry; or take a bus. In June in El Calafate, expect temperatures between 37°F during the day and 35°F at night. Cap off your sightseeing on the 29th (Mon) early enough to catcht the bus to Los Glaciares National Park.

Things to do in El Calafate

Parks Wildlife Nature
Highlights from your plan
Parque Nacional Los Glaciares ©
Parque Nacional Los Glaciares
Patagonia Profunda - Safari Experience ©

2
nights
Los Glaciares National Park, Argentina

Los Glaciares National Park ©
A World Heritage Site, Los Glaciares National Park contains a giant ice cap that feeds 47 vast glaciers.
On the next day, explore the striking landscape at Glaciar Seco and then explore the striking landscape at Glaciar Spegazzini.

For maps, reviews, traveler tips, and more tourist information, use the Los Glaciares National Park road trip site .

Take a bus from El Calafate to Los Glaciares National Park in 2 hours. In June, daytime highs in Los Glaciares National Park are 37°F, while nighttime lows are 35°F. Wrap up your sightseeing on the 1st (Wed) to allow time to travel to San Carlos de Bariloche.

Things to do in Los Glaciares National Park

Parks Nature
Highlights from your plan
Glaciar Seco ©
Glaciar Seco
Glaciar Spegazzini ©
Glaciar Spegazzini

5
nights
San Carlos de Bariloche, Argentina

San Carlos de Bariloche
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
Head to Chocolates Rapanui and Feria Artesanal Municipalfor plenty of shopping. You'll explore the less-touristy side of things at Fishing Charters & Tours and Fenoglio Museo del Chocolate. Next up on the itinerary: take in the spiritual surroundings of Parroquia San Eduardo, get a new perspective on nature at Museo de la Patagonia, enjoy breathtaking views from Parque Nacional Nahuel Huapi, and have fun and explore at Museo Paleontologico Bariloche.

To see reviews, photos, ratings, and other tourist information, use the San Carlos de Bariloche travel planning site .

Getting from Los Glaciares National Park to San Carlos de Bariloche by flight takes about 5 hours. Other options: take a bus. While traveling from Los Glaciares National Park, expect a bit warmer days and slightly colder nights in San Carlos de Bariloche, ranging from highs of 44°F to lows of 28°F. Finish your sightseeing early on the 6th (Mon) so you can travel to Cordoba.

Things to do in San Carlos de Bariloche

Outdoors Parks Wildlife
Highlights from your plan
Catedral Alta Patagonis
Catedral Alta Patagonis
Fishing Charters & Tours
Chocolates Rapanui ©
Chocolates Rapanui

3
nights
Cordoba, Argentina

Cordoba ©
History lives on in the streets of Cordoba, Argentina's second-largest city.
Discover out-of-the-way places like Museo Historico UNC Manzana Jesuitica and Museo Emilio Caraffa. Let the collections at Colegio Nacional de Monserrat and Paseo de las Artes capture your imagination. Take a break from Cordoba with a short trip to Estancia Jesuitica Jesus Maria in Jesus Maria, about 1h 05 min away. Next up on the itinerary: see the interesting displays at Museo de Ninos Barrilete, admire the masterpieces at Museo Iberoamericano de Artesanias, take in the spiritual surroundings of Society of Jesus Church, and take an in-depth tour of Museo de Arte Religioso Juan de Tejeda.

To see more things to do, photos, where to stay, and tourist information, read our Cordoba tour itinerary website .

Traveling by flight from San Carlos de Bariloche to Cordoba takes 4.5 hours. Alternatively, you can drive; or take a bus. When traveling from San Carlos de Bariloche in July, plan for somewhat warmer days in Cordoba, with highs around 55°F, while nights are warmer with lows around 55°F. Wrap up your sightseeing on the 9th (Thu) early enough to travel to Mendoza.

Things to do in Cordoba

Museums Historic Sites Shopping

Side Trip

Estancia Jesuitica Jesus Maria
Highlights from your plan
Museo Historico UNC  Manzana Jesuitica ©
Colegio Nacional de Monserrat ©
Colegio Nacional de Monserrat
Estancia Jesuitica Jesus Maria ©
Estancia Jesuitica Jesus Maria

5
nights
Mendoza, Argentina

Mendoza ©
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Explore hidden gems such as Bodega Tierras Altas and Bodega Chandon. Museum-lovers will appreciate Finca Agostino and Museo Nacional Del Vino y la Vendimia. Venture out of the city with trips to Maipu (Familia Zuccardi & Carinae Vinedos & Bodega). There's more to do: learn about winemaking at Bodega Renacer and experience rural life at Olivicola Maguay.

To see photos, maps, ratings, and more tourist information, read our Mendoza trip maker site .

You can fly from Cordoba to Mendoza in 2 hours. Other options are to drive; or take a bus. Traveling from Cordoba in July, you can expect nighttime temperatures to be little chillier in Mendoza, with lows of 36°F. Finish your sightseeing early on the 14th (Tue) so you can travel to Bogota.

Things to do in Mendoza

Wineries Museums Shopping

Side Trip

Maipu
Highlights from your plan
Bodega Budeguer ©
Bodega Budeguer
Bodega Renacer ©
Bodega Renacer
Bodega Chandon ©
Bodega Chandon

5
nights
Bogota, Colombia

Bogota ©
Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Head to Mercado de las Pulgas de Usaquen and Parque 93for plenty of shopping. Museum-lovers will get to explore National Museum of Colombia and Museo Botero del Banco de la Republica. Take a break from Bogota with a short trip to Laguna de Guatavita in Tierra Negra, about 1h 10 min away. There's much more to do: see the interesting displays at Gold Museum (Museo del Oro), stroll around Parque de Usaquen, get engrossed in the history at Casa Museo Quinta de Bolivar, and explore the world behind art at Museo Santa Clara.

To see traveler tips, reviews, ratings, and other tourist information, go to the Bogota itinerary planner.

Getting from Mendoza to Bogota by flight takes about 8 hours. Other options: take a bus; or drive. Due to the time zone difference, you'll gain 2 hours traveling from Mendoza to Bogota. In July, Bogota is somewhat warmer than Mendoza - with highs of 65°F and lows of 48°F. Wrap up your sightseeing on the 19th (Sun) early enough to travel to Panama City.

Things to do in Bogota

Museums Parks Neighborhoods

Side Trip

Laguna de Guatavita
Highlights from your plan
Museo Nacional de Colombia ©
Museo Nacional de Colombia
Gold Museum (Museo del Oro) ©
Gold Museum (Museo del Oro)
Casa Museo Quinta de Bolivar ©
Casa Museo Quinta de Bolivar

5
nights
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Museo del Canal Interoceanico de Panama and Casco Viejo are good opportunities to explore the local culture. Do your shopping at Weil Art Gallery and AltaPlaza Mall. Take a break from Panama City with a short trip to Scuba & Snorkeling in Portobelo, about 1h 40 min away. The adventure continues: see what you can catch with a fishing tour, take in the spiritual surroundings of Bahai Temple, take in the architecture and atmosphere at Iglesia de San Francisco de Asis, and relax and rejuvenate at some of the best spas.

To find other places to visit, more things to do, traveler tips, and more tourist information, read our Panama City trip itinerary maker tool .

Traveling by combination of flight and taxi from Bogota to Panama City takes 2.5 hours. Alternatively, you can do a combination of flight and shuttle; or do a combination of bus, car, and ferry. Traveling from Bogota in July, things will get much hotter in Panama City: highs are around 88°F and lows about 77°F. Finish your sightseeing early on the 24th (Fri) to allow enough time to travel to San Andres Island.

Things to do in Panama City

Historic Sites Wildlife Tours

Side Trip

Scuba & Snorkeling
Highlights from your plan
Bahai Temple ©
Bahai Temple
Museo del Canal Interoceanico de Panama ©
Casco Viejo ©
Casco Viejo

6
nights
San Andres Island, Colombia

San Andres Island ©
The coral San Andres Island boasts a rich colonial history, exotic beaches, and a laidback, tropical lifestyle.
Island House Museum and Plaza Canon de Morgan are good opportunities to explore the local culture. You'll explore the less-touristy side of things at West View and Playa Charquitos. There's lots more to do: see some colorful creatures with a scuba or snorkeling tour, look for gifts at Esmeraldas Colombianas, enjoy the sand and surf at Playa de San Luis, and look for all kinds of wild species at Cayo El Acuario.

For other places to visit, ratings, reviews, and tourist information, use the San Andres Island tour planner .

Traveling by combination of shuttle and flight from Panama City to San Andres Island takes 2.5 hours. Alternatively, you can do a combination of taxi and flight. In July, plan for daily highs up to 86°F, and evening lows to 77°F. On the 30th (Thu), you'll travel back home.

Things to do in San Andres Island

Wildlife Parks Outdoors

Side Trip

Mare
Highlights from your plan
La Piscinita ©
La Piscinita
Scuba & Snorkeling
Cayo El Acuario ©
Cayo El Acuario

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