54 days in Cuba Itinerary

54 days in Cuba Itinerary

Created using Inspirock Cuba trip itinerary planner

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Route & dates

54 days in Cuba Itinerary

Start: Brussels
Fly:  14​h
1
Varadero
— 14 nights
Fly:  2​h 45​min
2
Cayo Largo
— 3 nights
+4
Fly + Foot + Bus + Foot + Bus:  3​h 15​min
3
Trinidad
— 6 nights
Drive:  4​h
4
Cayo Guillermo
— 2 nights
Fly:  5​h 30​min
5
Holguin
— 5 nights
Drive:  2​h 30​min
6
Santiago de Cuba
— 6 nights
Fly:  2​h 45​min
7
Havana
— 14 nights
Drive:  2​h 45​min
8
Vinales
— 2 nights
+5
Bus + Foot + Bus + Foot + Fly + Train:  17​h 15​min
End: Brussels

14
nights
Varadero

Varadero ©
One of the largest resort towns in the Caribbean, Varadero boasts a 20 km (12 mi) long stretch of sand, lined with hotels and all-inclusive resorts.
Explore Varadero's surroundings by going to Cardenas Cathedral (in Cardenas) and Matanzas (Aldea Taina, Pharmaceutical Museum, & more). There's still lots to do: kick back and relax at Varadero Beach, stroll through Cayos Blancos, stroll around Josone Park, and examine the collection at House of Rum.

For reviews, traveler tips, maps, and more tourist information, you can read our Varadero online attractions planner .

Brussels, Belgium to Varadero is an approximately 14-hour flight. You can also do a combination of train and flight; or do a combination of flight and bus. Traveling from Brussels to Varadero, you'll gain 6 hours due to the time zone difference. Plan for warmer temperatures traveling from Brussels in January, with highs in Varadero at 30°C and lows at 19°C. Finish up your sightseeing early on the 5th (Wed) so you can travel to Cayo Largo.

Things to do in Varadero

Outdoors Parks Museums

Side Trips

Matanzas, Cardenas
Highlights from your plan
Varadero Beach ©
Varadero Beach
Josone Park ©
Josone Park
Cuevas de Bellamar ©
Cuevas de Bellamar

3
nights
Cayo Largo

Cayo Largo ©
The stress of modern life feels a million miles away when you holiday on Cayo Largo, a small and unspoiled resort island off the coast of Cuba.
Cayo Largo is known for beaches, wildlife, adventure, and nature. Your plan includes some of its best attractions: stroll through Playa Paraiso, identify plant and animal life at Sea Turtle Hatchery, step off the mainland to explore Cayo Rico, and enjoy the sand and surf at Playa Mal Tiempo.

To see traveler tips, where to stay, and tourist information, read our Cayo Largo journey planner.

You can fly from Varadero to Cayo Largo in 3 hours. Traveling from Varadero in February, expect a bit warmer with lows of 23°C in Cayo Largo. Finish your sightseeing early on the 8th (Sat) so you can travel to Trinidad.

Things to do in Cayo Largo

Parks Outdoors Beaches
Highlights from your plan
Playa Paraiso ©
Playa Paraiso
Sirena Beach ©
Sirena Beach
Sea Turtle Hatchery ©
Sea Turtle Hatchery

6
nights
Trinidad

Trinidad ©
Built on sugar and seemingly preserved in molasses, the town of Trinidad attracts visitors with its well-aged 19th century architecture and rustic charm, showcasing the sounds, scents, and sights of days gone by.
Get out of town with these interesting Trinidad side-trips: Cienfuegos (Jagua Castle, Punta Gorda, & more) and Santa Clara (Statue of Che Guevara Holding a Child, Che Guevara Mausoleum, & more). Next up on the itinerary: enjoy the sand and surf at Ancon Beach, take your sightseeing to a higher altitude at Topes de Collantes, don't miss a visit to Trinidad de Cuba, and appreciate the views at San Luis Valley.

For more things to do, photos, and other tourist information, go to the Trinidad trip maker app .

The Route module can help you plan travel from Cayo Largo to Trinidad. In February in Trinidad, expect temperatures between 34°C during the day and 21°C at night. Finish your sightseeing early on the 14th (Fri) so you can drive to Cayo Guillermo.

Things to do in Trinidad

Parks Historic Sites Museums

Side Trips

Cienfuegos, Santa Clara, Cuba, Topes de Collantes, Trinidad de Cuba
Highlights from your plan
Ancon Beach ©
Ancon Beach
Che Guevara Mausoleum ©
Che Guevara Mausoleum
Topes de Collantes ©
Topes de Collantes

2
nights
Cayo Guillermo

Cayo Guillermo
A kay of the Jardines del Rey archipelago, Cayo Guillermo has become a popular international tourist destination, buoyed by the construction of luxury all inclusive resorts that dot the paradisal island.
On the 15th (Sat), step off the mainland to explore Cayo Media Luna, kick back and relax at Cayo Guillermo, and then enjoy the sand and surf at Playa Pilar. Get ready for a full day of sightseeing on the 16th (Sun): have some family-friendly fun at Rocarena Climbing Center and then identify plant and animal life at Birdwatching with Paulino Lopez Delgado.

For photos, where to stay, and more tourist information, refer to the Cayo Guillermo route site .

Drive from Trinidad to Cayo Guillermo in 4 hours. Alternatively, you can do a combination of bus, train, and taxi; or do a combination of bus and car. In February in Cayo Guillermo, expect temperatures between 32°C during the day and 23°C at night. Finish your sightseeing early on the 16th (Sun) to allow enough time to travel to Holguin.

Things to do in Cayo Guillermo

Parks Wildlife Outdoors

Side Trip

Cayo Coco
Highlights from your plan
Playa Pilar
Playa Pilar
Cayo Guillermo ©
Cayo Guillermo
Birdwatching with Paulino Lopez Delgado ©

5
nights
Holguin

Holguin ©
Not overly touristy, Holguin offers a different perspective on Cuban life, standing as a major city that doesn't seek to commercialize its past or cover itself in all inclusive resorts.
Venture out of the city with trips to Bayamo (Casa Natal De Carlos Manuel De Cespedes & Jardin Botanico de Cupaynicu), Bateria de Fernando VII (in Gibara) and Guardalavaca (Guardalavaca Flea Market & Las Guanas Eco-Archaeologic Trail). There's much more to do: kick back and relax at Guardalavaca Beach, explore the striking landscape of Parque Monumento Nacional Bariay, get great views at Hill of the Cross (Loma de la Cruz), and head off the coast to Cayo Saetia Island.

To see ratings, traveler tips, and more tourist information, read our Holguin trip planning site .

You can fly from Cayo Guillermo to Holguin in 5.5 hours. Alternatively, you can drive; or do a combination of taxi and bus. Expect a daytime high around 34°C in February, and nighttime lows around 22°C. Wrap up your sightseeing on the 21st (Fri) to allow time to drive to Santiago de Cuba.

Things to do in Holguin

Parks Outdoors Nature

Side Trips

Guardalavaca, Bayamo, Parque Monumento Nacional Bariay, Bateria de Fernando VII
Highlights from your plan
Guardalavaca Beach ©
Guardalavaca Beach
Playa Esmeralda ©
Playa Esmeralda
Cayo Saetia Island ©
Cayo Saetia Island

6
nights
Santiago de Cuba

Santiago de Cuba ©
Santiago de Cuba has taken almost as much influence from Haiti and the Dominican Republic as it has from Havana, distilling a concoction of cultures to create a city with a distinct identity.
Venture out of the city with trips to Basilica de la Virgen de la Caridad del Cobre (in El Cobre) and Zoologico de Piedra (in Guantanamo). There's much more to do: explore the different monuments and memorials at Cementerio Santa Ifigenia, get a taste of life in the country at Rancho El Dajao, make a trip to Casa Museo Granjita de Siboney, and stroll around Cespedes Park.

To see other places to visit, ratings, where to stay, and other tourist information, refer to the Santiago de Cuba vacation planner.

You can drive from Holguin to Santiago de Cuba in 2.5 hours. Other options are to take a train; or take a bus. In February, plan for daily highs up to 34°C, and evening lows to 24°C. Finish your sightseeing early on the 27th (Thu) to allow enough time to travel to Havana.

Things to do in Santiago de Cuba

Parks Historic Sites Nature

Side Trips

Cobre, Rancho El Dajao, Zoologico de Piedra, Basilica de la Virgen de la Caridad del Cobre, Sierra Maestra
Highlights from your plan
Cespedes Park ©
Cespedes Park
Cementerio Santa Ifigenia ©
Cementerio Santa Ifigenia
Castillo de San Pedro de la Roca ©
Castillo de San Pedro de la Roca

14
nights
Havana

Havana ©
Cuba's capital and major commercial center, Havana manages to be very old and very modern at the same time.
Take a break from Havana with a short trip to Las Terrazas Complex in Las Terrazas, about 1h 05 min away. There's still lots to do: get to know the fascinating history of Malecón of Havana, steep yourself in history at El Morro, make a trip to Plaza de la Catedral, and admire the masterpieces at Museu Nacional de Belas Artes de Cuba.

For more things to do, ratings, maps, and more tourist information, read our Havana trip itinerary builder website .

Fly from Santiago de Cuba to Havana in 3 hours. Alternatively, you can do a combination of train and flight; or drive. Plan for slightly colder nights when traveling from Santiago de Cuba in February since evenings lows in Havana dip to 19°C. Finish up your sightseeing early on the 12th (Thu) so you can go by car to Vinales.

Things to do in Havana

Historic Sites Museums Tours

Side Trips

Espiritu Santo Church (Iglesia Del Espiritu Santo), Las Terrazas Complex
Highlights from your plan
Plaza de la Catedral ©
Plaza de la Catedral
Malecón of Havana ©
Malecón of Havana
Old Havana ©
Old Havana

2
nights
Vinales

Vinales ©
Offering a taste of authentic rural life, Vinales remains a small agricultural town, dominated by surrounding low mountain ranges.
Kick off your visit on the 13th (Fri): Head underground at Cuevas de Santo Tomas, make a trip to Mural de la Prehistoria, then admire the verdant scenery at Valle de Vinales, and finally pause for some serene contemplation at Iglesia del Sagrado Corazon de Jesus.

Make your Vinales itinerary with Inspirock to find out what to see and where to go.

You can drive from Havana to Vinales in 3 hours. Alternatively, you can take a shuttle; or take a bus. In March, daily temperatures in Vinales can reach 33°C, while at night they dip to 21°C. Finish your sightseeing early on the 14th (Sat) so you can travel back home.

Things to do in Vinales

Parks Nature Historic Sites
Highlights from your plan
Valle de Vinales ©
Valle de Vinales
Cuevas de Santo Tomas ©
Cuevas de Santo Tomas
Mural de la Prehistoria ©
Mural de la Prehistoria

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