52 days in South America & Mexico Itinerary

52 days in South America & Mexico Itinerary

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Route & dates

52 days in South America & Mexico Itinerary

Start: Bristol, United Kingdom
Fly:  16​h 30​min
1
Cartagena, Colombia
— 5 nights
Fly:  3​h 30​min
2
Bogota, Colombia
— 3 nights
Fly:  3​h 45​min
3
Cusco, Peru
— 6 nights
Fly:  1​h 45​min
4
Lima, Peru
— 4 nights
Fly:  9​h 30​min
5
Punta Arenas, Chile
— 2 nights
bus:  3​h
6
Puerto Natales (Torres del Paine), Chile
— 1 night
+2
shuttle + taxi + Fly:  7​h 30​min
7
Ushuaia, Argentina
— 6 nights
Fly:  2​h
8
El Calafate, Argentina
— 5 nights
Fly:  3​h 45​min
9
San Carlos de Bariloche, Argentina
— 6 nights
Fly:  16​h 15​min
10
Mexico City, Mexico
— 4 nights
Fly:  5​h 15​min
11
Playa del Carmen, Mexico
— 5 nights
+2
bus + foot + Fly:  12​h 30​min
End: Bristol, United Kingdom

5
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Plaza Santo Domingo and Sanctuary of Saint Peter Claver are good opportunities to explore the local culture. Get outdoors at Playa Blanca and Scuba & Snorkeling. There's lots more to do: take in the spiritual surroundings of Convent of Santa Cruz de la Popa, don't miss a visit to Plaza de San Diego, get the lay of the land with Walking tours, and contemplate the long history of Walled City of Cartagena.

To see traveler tips, ratings, reviews, and more tourist information, go to the Cartagena road trip planner .

Bristol, UK to Cartagena is an approximately 16.5-hour flight. You can also do a combination of train and flight; or do a combination of train and flight. You'll gain 5 hours traveling from Bristol to Cartagena due to the time zone difference. In February, daytime highs in Cartagena are 36°C, while nighttime lows are 28°C. Wrap up your sightseeing on the 21st (Fri) to allow time to travel to Bogota.

Things to do in Cartagena

Historic Sites Outdoors Tours

Side Trip

Playa Blanca
Highlights from your plan
Torre del Reloj ©
Torre del Reloj
Plaza Santo Domingo ©
Plaza Santo Domingo
Scuba & Snorkeling

3
nights
Bogota, Colombia

Bogota ©
Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Deepen your sense of the past at sights like Catedral de Sal de Zipaquira and Bolivar plaza. Get a sense of the local culture at Gold Museum (Museo del Oro) and Museo Botero del Banco de la Republica. Get out of town with these interesting Bogota side-trips: Laguna de Guatavita (in Tierra Negra) and Catedral Diocesana (in Zipaquira). There's more to do: take in the awesome beauty at Monserrate.

For traveler tips, reviews, photos, and other tourist information, you can read our Bogota day trip planning website .

You can fly from Cartagena to Bogota in 3.5 hours. Alternatively, you can do a combination of bus and flight; or drive. Traveling from Cartagena in February, expect nights in Bogota to be cooler, around 9°C, while days are little chillier, around 24°C. Finish your sightseeing early on the 24th (Mon) to allow enough time to travel to Cusco.

Things to do in Bogota

Nature Parks Historic Sites

Side Trips

Zipaquira, Laguna de Guatavita
Highlights from your plan
Catedral de Sal de Zipaquira ©
Catedral de Sal de Zipaquira
Laguna de Guatavita ©
Laguna de Guatavita
Gold Museum (Museo del Oro) ©
Gold Museum (Museo del Oro)

6
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Get in touch with nature at River Rafting & Tubing and Santuario Animal de Cochahuasi. Your cultural itinerary includes sights like Sacsayhuaman and San Blas. Venture out of the city with trips to Pisac (in Pisac) and Maras (Moray & Salinas de Maras). Next up on the itinerary: delve into the distant past at Sacred Valley of the Incas, contemplate the long history of Tipon, indulge in some personalized pampering at some of the best spas, and admire the masterpieces at Museo de Arte Precolombino.

To find other places to visit, photos, traveler tips, and tourist information, read Cusco trip planner .

Traveling by flight from Bogota to Cusco takes 4 hours. Alternatively, you can drive; or take a bus. February in Cusco sees daily highs of 23°C and lows of 9°C at night. Finish your sightseeing early on the 1st (Sun) so you can travel to Lima.

Things to do in Cusco

Historic Sites Spas Tours

Side Trips

Maras, Pisac, Sacred Valley of the Incas
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Moray ©
Moray
San Blas ©
San Blas

4
nights
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Centro Historico de Lima and Huaca Pucllana are good opportunities to explore the local culture. Discover out-of-the-way places like Barranco and Balneario Embajadores. Go for a jaunt from Lima to Santa Maria Del Mar to see Playa Santa Maria del Mar about 1h 30 min away. And it doesn't end there: pause for some serene contemplation at Iglesia y Convento de San Francisco, ponder the design of Plaza de Armas (Plaza Mayor), get engrossed in the history at Museo Larco, and stroll through Playa Penascal.

For traveler tips, maps, photos, and tourist information, you can read our Lima trip itinerary website .

Getting from Cusco to Lima by flight takes about 2 hours. Other options: drive; or take a bus. When traveling from Cusco in March, plan for a bit warmer days in Lima, with highs around 32°C, while nights are much warmer with lows around 24°C. Finish up your sightseeing early on the 5th (Thu) so you can travel to Punta Arenas.

Things to do in Lima

Outdoors Beaches Parks

Side Trip

Playa Santa Maria del Mar
Highlights from your plan
Playa Santa Maria del Mar ©
Playa Santa Maria del Mar
Centro Historico de Lima ©
Centro Historico de Lima
Barranco ©
Barranco

2
nights
Punta Arenas, Chile

Punta Arenas ©
An erstwhile hub of the sheep wool industry, Punta Arenas has evolved into a gateway of sorts for hikers, cruise ship passengers, and adventure travelers heading out on the windswept lands of Chile's extreme southern reaches.
Discover out-of-the-way places like Cementerio Municipal and Monumento Al Ovejero. Get some cultural insight at Nao Victoria Museo and Museo Regional De Magallanes. There's still lots to do: see the interesting displays at Palacio Sara Braun, brush up on your military savvy at Museo Naval y Maritimo, head outdoors with Outdoor Activities, and don't miss a visit to Plaza Munoz Gamero.

To find ratings, other places to visit, where to stay, and other tourist information, refer to the Punta Arenas trip planner .

Fly from Lima to Punta Arenas in 9.5 hours. Alternatively, you can do a combination of flight and bus; or drive. The time zone difference moving from Peru Time (PET) to Chile Time (CLT) is 1 hour. Traveling from Lima in March, expect Punta Arenas to be cooler, temps between 15°C and 5°C. Finish up your sightseeing early on the 8th (Sun) so you can catcht the bus to Puerto Natales (Torres del Paine).

Things to do in Punta Arenas

Outdoors Tours Wildlife
Highlights from your plan
Cementerio Municipal ©
Cementerio Municipal
Nao Victoria Museo ©
Nao Victoria Museo
Dolphin & Whale Watching

1
night
Puerto Natales (Torres del Paine), Chile

Surrounded by towering mountains, shimmering lakes, and the region's rugged hills, Puerto Natales serves as a bustling jumping-off point for exploring the Torres del Paine National Park.
On the 9th (Mon), explore the fascinating underground world of Mylodon Cave Natural Monument, cast your line with a fishing tour, and then make a trip to Muelle Historico.

To see where to stay, photos, other places to visit, and tourist information, read our Puerto Natales (Torres del Paine) trip itinerary builder app .

Traveling by bus from Punta Arenas to Puerto Natales (Torres del Paine) takes 3 hours. Alternatively, you can drive. In March, daytime highs in Puerto Natales (Torres del Paine) are 16°C, while nighttime lows are 9°C. Finish your sightseeing early on the 9th (Mon) so you can travel to Ushuaia.

Things to do in Puerto Natales (Torres del Paine)

Tours Wildlife Outdoors
Highlights from your plan
Fishing Charters & Tours
Mylodon Cave Natural Monument ©
Mylodon Cave Natural Monument
Muelle Historico ©
Muelle Historico

6
nights
Ushuaia, Argentina

Ushuaia ©
Often called the "End of the World" because of its position on the southernmost tip of South America, the expanding city of Ushuaia serves as both a busy commercial port and attractive tourist hub.
You'll discover tucked-away gems like Bahia Lapataia and Glacier Martial. Get in touch with nature at Laguna Esmeralda and Nature & Wildlife Tours. Go for a jaunt from Ushuaia to Tolhuin to see Cerro Jeujepen about 1h 55 min away. There's still lots to do: step off the mainland to explore Isla Martillo, pause for some photo ops at Plaza Malvinas, contemplate the waterfront views at Lago Roca, and take your sightseeing to a higher altitude at Glaciar Martial.

To find photos, other places to visit, more things to do, and tourist information, read our Ushuaia trip itinerary website .

Do a combination of bus and flight from Puerto Natales (Torres del Paine) to Ushuaia in 7.5 hours. Alternatively, you can take a bus; or take a bus. Due to the time zone difference, you'll lose 1 hour traveling from Puerto Natales (Torres del Paine) to Ushuaia. Traveling from Puerto Natales (Torres del Paine) in March, plan for a bit cooler nights in Ushuaia, with lows around 5°C. Cap off your sightseeing on the 16th (Mon) early enough to travel to El Calafate.

Things to do in Ushuaia

Parks Nature Outdoors

Side Trips

Glaciar Martial, Lago Roca, Cerro Jeujepen
Highlights from your plan
Laguna Esmeralda ©
Laguna Esmeralda
Cerro Castor (Castor Mount) ©
Cerro Castor (Castor Mount)
Glacier Martial ©
Glacier Martial

5
nights
El Calafate, Argentina

El Calafate ©
El Calafate tourism thrives mostly thanks to the city's proximity to a World Heritage-listed national park, famed for containing over 40 large glaciers.
You'll discover tucked-away gems like Lago Argentino and Estacionamiento Pasarelas Glaciar Perito Moreno. Get outdoors at Parque Nacional Los Glaciares and Kayaking & Canoeing. There's lots more to do: explore the striking landscape at Upsala Glacier, see the interesting displays at Glaciarium Museo del Hielo Patagónico, head outdoors with Outdoor Activities, and identify plant and animal life at Laguna Nimez Reserva Natural Municipal.

For ratings, where to stay, photos, and tourist information, you can read our El Calafate road trip planning site .

Getting from Ushuaia to El Calafate by flight takes about 2 hours. Other options: do a combination of car and ferry; or take a bus. Expect a bit warmer evenings in El Calafate when traveling from Ushuaia in March, with lows around 13°C. Wrap up your sightseeing on the 21st (Sat) early enough to travel to San Carlos de Bariloche.

Things to do in El Calafate

Parks Nature Tours
Highlights from your plan
Parque Nacional Los Glaciares ©
Parque Nacional Los Glaciares
Upsala Glacier ©
Upsala Glacier

6
nights
San Carlos de Bariloche, Argentina

San Carlos de Bariloche ©
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
You'll discover tucked-away gems like Cerro Tronador and Parque Nacional Nahuel Huapi. Get outdoors at Nature & Wildlife Tours and Puerto Blest y Cascada de los Cantaro. Venture out of the city with trips to Rio Correntoso (in Villa La Angostura) and Mirador Lago Traful (in Villa Traful). Next up on the itinerary: get a new perspective on things with Boat Tours & Water Sports, walk around Parque Nahuelito, take in the waterfront at Isla Victoria, and cast your line with a fishing tour.

For where to stay, reviews, photos, and tourist information, you can read our San Carlos de Bariloche road trip app .

Fly from El Calafate to San Carlos de Bariloche in 4 hours. Alternatively, you can take a bus; or drive. When traveling from El Calafate in March, plan for somewhat warmer days and slightly colder nights in San Carlos de Bariloche: temperatures range from 23°C by day to 5°C at night. Finish up your sightseeing early on the 27th (Fri) so you can travel to Mexico City.

Things to do in San Carlos de Bariloche

Outdoors Parks Nature

Side Trips

Mirador Lago Traful, Rio Correntoso
Highlights from your plan
Ventisquero Negro ©
Ventisquero Negro
Parque Nacional Nahuel Huapi ©
Parque Nacional Nahuel Huapi
Nature & Wildlife Tours

4
nights
Mexico City, Mexico

Mexico City ©
Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Popular historic sites such as Zona Arqueológica de Teotihuacan Estacionamiento Puerta 5 and Historic Center (Centro Historico) are in your itinerary. Discover out-of-the-way places like Basilica de Santa Maria de Guadalupe and Zocalo. Next up on the itinerary: examine the collection at Museo Nacional de Antropologia, admire the masterpieces at Palacio de Bellas Artes, explore the ancient world of Metropolitan Cathedral (Catedral Metropolitana), and take in the architecture and atmosphere at Iglesia de Nuestra Senora de Guadalupe.

Make your Mexico City itinerary with Inspirock to find out what to see and where to go.

Fly from San Carlos de Bariloche to Mexico City in 16.5 hours. The time zone difference moving from Argentine Time (ART) to Central Standard Time (CST) is minus 3 hours. Expect a bit warmer temperatures when traveling from San Carlos de Bariloche in March; daily highs in Mexico City reach 28°C and lows reach 12°C. Finish your sightseeing early on the 1st (Wed) so you can travel to Playa del Carmen.

Things to do in Mexico City

Historic Sites Museums Neighborhoods

Side Trip

Zona Arqueológica de Teotihuacan Estacionamiento Puerta 5
Highlights from your plan

5
nights
Playa del Carmen, Mexico

The tourist hub of the popular Mayan Riviera, upscale Playa del Carmen remains the jewel of Mexico's Caribbean coastline.
Get some historical perspective at Tulum Archaeological Site and Cobá Zona Arqueológica Cobá. Nuestra Senora del Carmen Catholic Church and Balam Art On Feathers are good opportunities to explore the local culture. Get out of town with these interesting Playa del Carmen side-trips: Tulum (Climbing Tours & Gran Cenote) and Cozumel (Scuba & Snorkeling, Paradise Beach Cozumel, & more).

To find other places to visit, reviews, more things to do, and other tourist information, go to the Playa del Carmen road trip planning tool .

You can fly from Mexico City to Playa del Carmen in 5.5 hours. Alternatively, you can do a combination of bus and flight; or drive. Due to the time zone difference, you'll lose 1 hour traveling from Mexico City to Playa del Carmen. Plan for somewhat warmer nights when traveling from Mexico City in April since evenings lows in Playa del Carmen dip to 24°C. Finish your sightseeing early on the 6th (Mon) so you can travel back home.

Things to do in Playa del Carmen

Outdoors Tours Wildlife

Side Trips

Cozumel, Tulum, Cobá Zona Arqueológica Cobá
Highlights from your plan
Climbing Tours
Palancar Reef ©
Palancar Reef
Tulum Archaeological Site ©
Tulum Archaeological Site

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