52 days in South America & Mexico Itinerary

52 days in South America & Mexico Itinerary

Created using Inspirock trip planner

Make it your trip
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Santiago, Chile
— 30 nights
Fly
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Montevideo, Uruguay
— 5 nights
Fly
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Lima, Peru
— 3 nights
Fly
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Cusco, Peru
— 4 nights
Bus to Ollantaytambo, Train to Machu Picchu
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Machu Picchu, Peru
— 3 nights
+2
Drive to Alejandro Velasco Astete International Airport, Fly to General Francisco J. Mujica International Airport, Drive to Acambaro
6
Acambaro, Mexico
— 5 nights

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Santiago, Chile

— 30 nights

City of the Island Hills

Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Venture out of the city with trips to Valle Nevado - Ski Resort Chile (in Valle Nevado), Algarrobo (Cinco Oceanos Dive Center & Canopy El Canelo) and Casa de Isla Negra (in Isla Negra). On the 6th (Sun), give your taste buds a day to remember with a local gastronomic tour. Saddle up on the 10th (Thu) and explore with a tour on horseback. There's still lots to do: take your sightseeing to a higher altitude at San Cristóbal Hill, take an in-depth tour of Museo Chileno de Arte Precolombino, admire the landmark architecture of Metropolitan Cathedral (Catedral Metropolitana), and examine the collection at La Sebastiana.

To see photos, other places to visit, more things to do, and more tourist information, refer to the Santiago trip itinerary website.

If you are flying in from United States, the closest major aiport is Comodoro Arturo Merino Benítez International Airport. Finish your sightseeing early on the 27th (Sun) to allow enough time to travel to Montevideo.

Things to do in Santiago

Tours · Museums · Parks · Wineries

Side Trips

Montevideo, Uruguay

— 5 nights
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
When in Montevideo, make a side trip to see Pizzorno Family Estates in Canelones, approximately Canelones away. Next up on the itinerary: take in the pleasant sights at Rambla de Montevideo, make a trip to Plaza Independencia, explore the world behind art at Museo Municipal de Bellas Artes Juan Manuel Blanes, and ponder the world of politics at Palacio Legislativo.

For photos, other places to visit, ratings, and tourist information, go to the Montevideo trip maker website.

You can fly from Santiago to Montevideo in 6 hours. Other options are to drive; or take a bus. You'll lose 1 hour traveling from Santiago to Montevideo due to the time zone difference. In June, daily temperatures in Montevideo can reach 61°F, while at night they dip to 44°F. Wrap up your sightseeing on the 2nd (Fri) early enough to travel to Lima.

Things to do in Montevideo

Wineries · Museums · Neighborhoods · Tours

Side Trip

Lima, Peru

— 3 nights

City of the Kings

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Lima is known for museums, parks, and historic sites. Your plan includes some of its best attractions: take an in-depth tour of Museo Larco, stroll around Circuito Magico Del Agua, take in the architecture and atmosphere at Museo Convento San Francisco y Catacumbas, and get the lay of the land with Walking tours.

For reviews, traveler tips, and other tourist information, refer to the Lima trip itinerary maker site.

You can fly from Montevideo to Lima in 8 hours. Alternatively, you can drive; or take a bus. The time zone difference moving from Uruguay Standard Time (UYT) to Peru Standard Time (PET) is minus 2 hours. In July, Lima is somewhat warmer than Montevideo - with highs of 66°F and lows of 61°F. Wrap up your sightseeing on the 5th (Mon) early enough to travel to Cusco.

Things to do in Lima

Historic Sites · Tours · Neighborhoods · Museums

Cusco, Peru

— 4 nights

Imperial City

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
On the 9th (Fri), spend a fun day on foot with Walking tours. There's much more to do: steep yourself in history at Sacsayhuaman, wander the streets of San Blas, explore the world behind art at Museo de Arte Precolombino, and delve into the distant past at Centro Historico De Cusco.

To find maps, where to stay, ratings, and other tourist information, you can read our Cusco online travel route planner.

Traveling by flight from Lima to Cusco takes 3.5 hours. Alternatively, you can drive; or take a bus. Plan for much colder nights when traveling from Lima in July since evenings lows in Cusco dip to 34°F. Finish your sightseeing early on the 9th (Fri) to allow enough time to travel to Machu Picchu.

Things to do in Cusco

Historic Sites · Tours · Museums · Neighborhoods

Machu Picchu, Peru

— 3 nights
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Change things up with a short trip to Zipline in Santa Teresa (about 32 minutes away). There's lots more to do: contemplate the long history of Santuario Historico de Machu Picchu, indulge in some personalized pampering at SPA Rocas Sagradas, get great views at Intipuncu, and don't miss a visit to Plaza Manco Capac.

To find ratings, other places to visit, reviews, and more tourist information, go to the Machu Picchu holiday planner.

Traveling by combination of bus and train from Cusco to Machu Picchu takes 4 hours. Alternatively, you can take a train; or drive. Finish up your sightseeing early on the 12th (Mon) so you can travel to Acambaro.

Things to do in Machu Picchu

Historic Sites · Parks · Tours · Adventure

Side Trip

Acambaro, Mexico

— 5 nights
Acámbaro is a city and municipality in the southeastern corner of the Mexican state of Guanajuato, on the banks of the Lerma River, and the oldest of the 46 municipalities of Guanajuato. Venture out of the city with trips to Museo Ex Convento de San Agustin de San Pablo (in Yuriria), El Oro (Socavon de San Juan, EL Oro de Hidalgo Pueblo Magico, &more) and Tlalpujahua (Santuario del Carmen & Museo Mina Dos Estrellas). There's lots more to do: head outdoors with Crater Rincon de Parangueo, get to know the resident critters at Mundo Granjero & Zoo, stroll through La Reserva de la Biosfera Mariposa Monarca, and take in the architecture and atmosphere at Parroquia de San Francisco.

For ratings, maps, photos, and more tourist information, use the Acambaro trip maker site.

The Route module can help you plan travel from Machu Picchu to Acambaro. Due to the time zone difference, you'll gain 1 hour traveling from Machu Picchu to Acambaro. In July, daytime highs in Acambaro are 80°F, while nighttime lows are 56°F.

Things to do in Acambaro

Parks · Museums · Zoos & Aquariums · Wildlife

Side Trips

Mexico travel guide

4.5
Ruins · Beaches · Landmarks
Tailor-made for anyone seeking that traditional sun-and-sand experience, Mexico vacations allow visitors to explore nearly 10,000 km (6,200 mi) of picturesque coastlines. Idyllic beaches and favorable year-round weather aside, this diverse country with a rich pre-Colombian history allows tourists a chance to discover a fascinating cuisine, numerous archaeological sites, state-of-the-art museums, colonial-era haciendas, and outstanding examples of 21st-century architecture. Most visitors get to know the country by its cities, but if you want a well-rounded Mexico tour, spend some time exploring its jungles, cloud forests, Caribbean reefs, snowcapped volcanoes, vast deserts, and tranquil lagoons. Life is lived outdoors in Mexico, so wherever you go, don't forget to dine alfresco and stroll the country's colonial streets.