42 days in Peru, Bolivia & Argentina Itinerary

42 days in Peru, Bolivia & Argentina Itinerary

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42 days in Peru, Bolivia & Argentina Itinerary

Start: Dublin, Ireland
Fly:  22​h 30​min
1
Puno, Peru
— 3 nights
Drive:  12​h 45​min
2
Ica, Peru
— 1 night
+2
bus + taxi + Fly:  4​h
3
Cusco, Peru
— 3 nights
+2
bus + foot + train:  3​h 15​min
4
Machu Picchu, Peru
— 2 nights
Drive:  11​h
5
Rurrenabaque, Bolivia
— 1 day
Fly:  2​h 45​min
6
La Paz, Bolivia
— 2 nights
Fly + taxi:  3​h 45​min
7
Uyuni, Bolivia
— 1 night
taxi + Fly:  9​h 15​min
8
Salta, Argentina
— 2 nights
Fly:  2​h 15​min
9
Mendoza, Argentina
— 3 nights
Fly:  6​h 45​min
10
Ushuaia, Argentina
— 4 nights
Fly:  3​h 15​min
11
Los Glaciares National Park, Argentina
— 3 nights
Drive:  6​h 45​min
12
Perito Moreno, Argentina
— 3 nights
Drive:  10​h 15​min
13
Puerto Madryn, Argentina
— 3 nights
Fly:  3​h 30​min
14
Buenos Aires, Argentina
— 3 nights
Fly:  3​h 30​min
15
Iguazu National Park, Argentina
— 2 nights
Fly:  18​h 30​min
End: Dublin, Ireland

3
nights
Puno, Peru

Puno ©
Hugging the western tip of Lake Titicaca, Puno serves as a melting pot of indigenous and imported cultures, and makes a great base for explorations around the region.
Your day-by-day itinerary now includes Lake Titicaca. Visit Sillustani and Iglesia Apostol Santiago for their historical value. Your cultural itinerary includes sights like Catedral de Chucuito and Museo Carlos Dreyer. There's still lots to do: step off the mainland to explore Taquile Island, contemplate in the serene atmosphere at Iglesia San Antonio, contemplate the long history of La Casa del Corregidor, and take a stroll through Luquina Chico.

To see ratings, more things to do, reviews, and other tourist information, read our Puno trip planner .

Dublin, Ireland to Puno is an approximately 22.5-hour flight. You can also do a combination of flight and bus. Traveling from Dublin to Puno, you'll gain 5 hours due to the time zone difference. Expect slightly colder evenings in Puno when traveling from Dublin in September, with lows around 0°C. You will have some time to spend on the 10th (Thu) before leaving for Ica.

Things to do in Puno

Nature Parks Historic Sites

Side Trip

Iglesia Apostol Santiago
Highlights from your plan
Lake Titicaca ©
Lake Titicaca
Sillustani ©
Sillustani
Iglesia Apostol Santiago ©
Iglesia Apostol Santiago

1
night
Ica, Peru

Ica ©
Located on the Ica River in the desert areas of Peru's southern coast, the city of Ica stands as something of an oasis in the dry, barren landscape.
Your day-by-day itinerary now includes Laguna De Huacachina. Start off your visit on the 11th (Fri): learn about winemaking at Tacama, then take in the spiritual surroundings of Catedral de Ica, then take in the architecture and atmosphere at Santuario del Senor de Luren, and finally contemplate the waterfront views at Laguna De Huacachina. Get ready for a full day of sightseeing on the 12th (Sat): see the interesting displays at Regional Museum of Ica, then walk around Parque De Las Brujas De Cachiche, and then take in breathtaking views at Canon de los Perdidos.

To find more things to do, other places to visit, reviews, and tourist information, refer to the Ica route tool .

You can drive from Puno to Ica in 13 hours. Other options are to take a bus; or do a combination of bus and flight. Traveling from Puno in September, Ica is much warmer at night with lows of 16°C. Wrap up your sightseeing on the 12th (Sat) early enough to travel to Cusco.

Things to do in Ica

Parks Nature Wineries
Highlights from your plan
Parque De Las Brujas De Cachiche ©
Parque De Las Brujas De Cachiche
Santuario del Senor de Luren ©
Santuario del Senor de Luren
Regional Museum of Ica
Regional Museum of Ica

3
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Start off your visit on the 13th (Sun): delve into the distant past at Tambomachay, explore the ancient world of Q'enqo, then delve into the distant past at Sacsayhuaman, and finally contemplate the long history of Plaza de Armas. Keep things going the next day: look for all kinds of wild species at Santuario Animal de Cochahuasi, explore the ancient world of Tipon, then don't miss a visit to San Pedro Apostol de Andahuaylillas, and finally delve into the distant past at Piquillacta.

To find other places to visit, reviews, more things to do, and tourist information, read Cusco trip itinerary planner.

You can do a combination of bus and flight from Ica to Cusco in 4 hours. Alternatively, you can drive; or take a bus. Traveling from Ica in September, plan for a bit cooler nights in Cusco, with lows around 5°C. Wrap up your sightseeing on the 15th (Tue) early enough to travel to Machu Picchu.

Things to do in Cusco

Historic Sites Wildlife Parks

Side Trips

San Pedro Apostol de Andahuaylillas, Piquillacta
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Tipon ©
Tipon
Q'enqo ©
Q'enqo

2
nights
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Step out of the city life by going to Santuario Historico de Machu Picchu and Los Jardines de Mandor. Visit Winay Wayna and Iglesia Virgen Del Carmen for their historical value. There's still lots to do: look for all kinds of wild species at Jardin Botanico en Machu Pichu, see the interesting displays at Museo de Sitio Manuel Chavez Ballon, catch some excitement at Samay Spa, and stop by Artesanias.

For photos, other places to visit, more things to do, and more tourist information, you can read our Machu Picchu vacation app .

You can do a combination of bus and train from Cusco to Machu Picchu in 3.5 hours. Alternatively, you can take a train; or drive. On the 17th (Thu), wrap the sightseeing up by early afternoon so you can travel to Rurrenabaque.

Things to do in Machu Picchu

Historic Sites Wildlife Parks
Highlights from your plan
Santuario Historico de Machu Picchu ©
Winay Wayna ©
Winay Wayna
Los Jardines de Mandor ©
Los Jardines de Mandor

1
day
Rurrenabaque, Bolivia

Rurrenabaque
A holiday in Rurrenabaque is a great option for those interested in exploring the region's amazing natural biodiversity, breathtaking landscapes, and native cultures of the area.
On the 18th (Fri), tee off at El Chocolatal Golf Eco Resort and then get outside with Canopy Villa Alcira.

To find where to stay, traveler tips, reviews, and more tourist information, read Rurrenabaque day trip planner .

Use the Route module to find suitable travel options from Machu Picchu to Rurrenabaque. The time zone changes from Peru Time to Bolivia Time, which is usually a 1 hour difference. In September, daytime highs in Rurrenabaque are 38°C, while nighttime lows are 23°C. Finish up your sightseeing early on the 18th (Fri) so you can travel to La Paz.

Things to do in Rurrenabaque

Outdoors Golf

2
nights
La Paz, Bolivia

La Paz ©
Take a moment to catch your breath as you commence your holiday in La Paz.
Start off your visit on the 19th (Sat): explore the ancient world of Tiwanaku, examine the collection at National Museum of Ethnography and Folklore, and then examine the collection at Museum of Musical Instruments - Museo Instrumentos Musicales de Bolivia. Get ready for a full day of sightseeing on the next day: fly down the slopes at Scree Rush, then take in the architecture and atmosphere at Catedral Basilica Menor de Nuestra Senora de la Paz, and then sample the fine beverages at Andean Culture Distillery.

To see where to stay, traveler tips, photos, and tourist information, go to the La Paz trip itinerary maker website .

Traveling by flight from Rurrenabaque to La Paz takes 3 hours. Alternatively, you can drive; or take a bus. Plan for much colder temperatures traveling from Rurrenabaque in September, with highs in La Paz at 18°C and lows at 0°C. Cap off your sightseeing on the 20th (Sun) early enough to travel to Uyuni.

Things to do in La Paz

Winter Sports Outdoors Wildlife
Highlights from your plan
Tiwanaku ©
Tiwanaku

1
night
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Start off your visit on the 21st (Mon): contemplate the geological forces at Tunupa Volcano.

For traveler tips, other places to visit, maps, and tourist information, use the Uyuni trip itinerary maker .

Getting from La Paz to Uyuni by combination of flight and taxi takes about 4 hours. Other options: drive; or do a combination of bus and taxi. Expect much colder weather when traveling from La Paz in September: highs in Uyuni hover around 1°C, while lows dip to 0°C. Cap off your sightseeing on the 21st (Mon) early enough to travel to Salta.

Things to do in Uyuni

Nature Parks
Highlights from your plan
Tunupa Volcano ©
Tunupa Volcano

2
nights
Salta, Argentina

Salta ©
Salta boasts a vibrant social life and array of informative museums appealing to visitors looking for a memorable cultural experience.
Visit Iglesia San Francisco and Immaculada Madre del Divino Corazon Eucaristico de Jesus for their historical value. Get a sense of the local culture at Iglesia Nuestra Senora de La Candelaria de La Vina and La Caldera. There's lots more to do: see the interesting displays at Salta Cabildo, take in the dramatic natural features at Alemania, explore the activities along Ojo de Mar, and take in the architecture and atmosphere at Nuestra Senora de la Merced.

To see where to stay, more things to do, traveler tips, and other tourist information, read Salta trip planning app .

You can do a combination of taxi and flight from Uyuni to Salta in 9.5 hours. Other options are to drive; or do a combination of taxi, train, car, and bus. You'll lose 1 hour traveling from Uyuni to Salta due to the time zone difference. When traveling from Uyuni in September, plan for warmer days in Salta, with highs around 28°C, while nights are a bit warmer with lows around 9°C. Wrap up your sightseeing on the 24th (Thu) early enough to travel to Mendoza.

Things to do in Salta

Parks Wildlife Outdoors

Side Trips

Reserva del Huaico, Ojo de Mar
Highlights from your plan
Iglesia San Francisco ©
Iglesia San Francisco
Salta Cabildo ©
Salta Cabildo

3
nights
Mendoza, Argentina

Mendoza ©
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Step off the beaten path and head to Bodega Tierras Altas and Los Pingos Horse Riding. Satisfy your inner culture vulture at Bodega Renacer and Bodega Chandon. Step out of Mendoza to go to Maipu and see Familia Zuccardi, which is approximately 48 minutes away. There's more to do: learn about winemaking at Bodega Cruzat. Bubbles Experience and take in the architecture and atmosphere at Santuario de la Virgen de Lourdes.

To see more things to do, reviews, where to stay, and other tourist information, refer to the Mendoza day trip planning website .

Traveling by flight from Salta to Mendoza takes 2.5 hours. Alternatively, you can drive; or take a bus. September in Mendoza sees daily highs of 25°C and lows of 9°C at night. Wrap up your sightseeing on the 27th (Sun) early enough to travel to Ushuaia.

Things to do in Mendoza

Wineries Trails Outdoors

Side Trip

Familia Zuccardi
Highlights from your plan
Bodega Renacer ©
Bodega Renacer
Bodega Chandon ©
Bodega Chandon
Familia Zuccardi ©
Familia Zuccardi

4
nights
Ushuaia, Argentina

Ushuaia ©
Often called the "End of the World" because of its position on the southernmost tip of South America, the expanding city of Ushuaia serves as both a busy commercial port and attractive tourist hub.
Get in touch with nature at Lago Roca and Glaciar Martial. Satisfy your inner culture vulture at Estancia Harberton and Acatushun Museum. And it doesn't end there: surround yourself with nature on a nature and wildlife tour, explore the landscape on two wheels at Ushuaia Bay, don't miss a visit to Eva Peron, and enjoy the sand and surf at Playa Larga.

For reviews, more things to do, other places to visit, and other tourist information, refer to the Ushuaia trip planner .

Traveling by flight from Mendoza to Ushuaia takes 7 hours. Alternatively, you can do a combination of car and ferry; or take a bus. Traveling from Mendoza in September, expect nights in Ushuaia to be slightly colder, around 1°C, while days are much colder, around 8°C. Wrap up your sightseeing on the 1st (Thu) early enough to travel to Los Glaciares National Park.

Things to do in Ushuaia

Outdoors Parks Trails

Side Trips

Glaciar Martial, Lago Roca
Highlights from your plan
Lago Roca ©
Lago Roca
Nature & Wildlife Tours
Ushuaia Bay ©
Ushuaia Bay

3
nights
Los Glaciares National Park, Argentina

Los Glaciares National Park ©
A World Heritage Site, Los Glaciares National Park contains a giant ice cap that feeds 47 vast glaciers.
Kick off your visit on the 2nd (Fri): take in the dramatic natural features at Perito Moreno Glacier. On the 3rd (Sat), you'll have a packed day of sightseeing: explore the striking landscape at Glaciar Seco and then take in the dramatic natural features at Glaciar Spegazzini.

For other places to visit, photos, and tourist information, use the Los Glaciares National Park holiday planning tool .

Fly from Ushuaia to Los Glaciares National Park in 3.5 hours. Alternatively, you can do a combination of car and ferry; or take a bus. Traveling from Ushuaia in October, expect somewhat warmer with lows of 8°C in Los Glaciares National Park. Wrap up your sightseeing on the 4th (Sun) to allow time to travel to Perito Moreno.

Things to do in Los Glaciares National Park

Nature Parks
Highlights from your plan
Perito Moreno Glacier ©
Perito Moreno Glacier
Glaciar Spegazzini ©
Glaciar Spegazzini
Glaciar Seco ©
Glaciar Seco

3
nights
Perito Moreno, Argentina

Perito Moreno ©
Perito Moreno is a town in the northwest of Santa Cruz Province, Argentina, 25 km east of Lake Buenos Aires. Explore hidden gems such as Parque Nacional Patagonia and Chacra Don Neno. Escape the urban bustle at Portal La Ascension and Monte Zeballos.

To plan Perito Moreno vacation without wasting time, ask Inspirock to design an itinerary.

The Route module can help you plan travel from Los Glaciares National Park to Perito Moreno. While traveling from Los Glaciares National Park, expect somewhat warmer days and slightly colder nights in Perito Moreno, ranging from highs of 17°C to lows of 3°C. On the 7th (Wed), you're off toPuerto Madryn.

Things to do in Perito Moreno

Parks Outdoors Nature

Side Trip

Los Antiguos
Highlights from your plan
Monte Zeballos ©
Monte Zeballos
Chacra Don Neno ©
Chacra Don Neno

3
nights
Puerto Madryn, Argentina

Puerto Madryn ©
Whales and penguins frolic in the waters of Puerto Madryn, one of Argentine Patagonia's most important port cities.
On the 8th (Thu), tour the pleasant surroundings at Playa El Doradillo, contemplate the long history of The Town of Gaiman, and then kick back and relax at Playa Parana. On the 9th (Fri), you'll have a packed day of sightseeing: examine the collection at Museo Pueblo de Luis, then get a new perspective on nature at Museo Paleontologico Egidio Feruglio, and then tour the pleasant surroundings at Costas de Patagonia.

To find more things to do, photos, where to stay, and more tourist information, read Puerto Madryn trip builder app .

You can drive from Perito Moreno to Puerto Madryn in 10.5 hours. On the 10th (Sat), wrap the sightseeing up by early afternoon so you can travel to Buenos Aires.

Things to do in Puerto Madryn

Outdoors Beaches Parks

Side Trip

Trelew
Highlights from your plan
Playa El Doradillo ©
Playa El Doradillo
Scuba & Snorkeling
Museo Paleontologico Egidio Feruglio ©

3
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Your inner history buff will appreciate Basilica del Santisimo Sacramento and Basilica de Lujan. Do some cultural sightseeing at Catedral de San Isidro and Basilica de Nuestra Senora Del Pilar. Explore Buenos Aires' surroundings by going to Peru Beach (in Acassuso), Museos & Cripta Basilica Nuestra Senora De Lujan (in Lujan) and Reserva Natural Urbana (in Castelar). The adventure continues: get outside with Delta El Tigre, take in nature's colorful creations at Parque 3 de Febrero, see the interesting displays at Museo River Plate, and shop like a local with Puerto Madero.

To see where to stay, ratings, photos, and tourist information, refer to the Buenos Aires online tour itinerary planner .

Getting from Puerto Madryn to Buenos Aires by flight takes about 3.5 hours. Other options: do a combination of bus and flight; or drive. In October, plan for daily highs up to 24°C, and evening lows to 17°C. Finish up your sightseeing early on the 13th (Tue) so you can travel to Iguazu National Park.

Things to do in Buenos Aires

Parks Outdoors Historic Sites

Side Trips

Lujan, Delta El Tigre, Reserva Natural Urbana, Peru Beach, Catedral de San Isidro
Highlights from your plan
Catedral de San Isidro ©
Catedral de San Isidro
Basilica del Santisimo Sacramento ©
Basilica del Santisimo Sacramento
Puerto Madero ©
Puerto Madero

2
nights
Iguazu National Park, Argentina

Iguazu National Park ©
Iguazu National Park contains 672 sq km (259 sq mi) of fertile subtropical forests, but its main attraction is the majestic Iguazu Falls.
Start off your visit on the 14th (Wed): admire the sheer force of Salto San Martin and then admire the sheer force of Iguazu Falls. Get ready for a full day of sightseeing on the next day: step off the mainland to explore Isla San Martin, admire the sheer force of Salto Bernabe Mendez, and then discover the riches below the earth's surface at Wanda Mines.

To see more things to do, traveler tips, where to stay, and tourist information, read Iguazu National Park itinerary planner.

You can fly from Buenos Aires to Iguazu National Park in 3.5 hours. Alternatively, you can drive; or take a bus. When traveling from Buenos Aires in October, plan for a bit warmer days and about the same nights in Iguazu National Park: temperatures range from 34°C by day to 19°C at night. Cap off your sightseeing on the 16th (Fri) early enough to travel back home.

Things to do in Iguazu National Park

Nature Parks Wildlife

Side Trip

Wanda Mines
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Salto Bernabe Mendez ©
Salto Bernabe Mendez
Salto San Martin ©
Salto San Martin

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