49 days in South America Itinerary

49 days in South America Itinerary

Created using Inspirock South America itinerary planner

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Route & dates

49 days in South America Itinerary

Start: Seattle, United States
Fly:  17​h 45​min
1
Cusco, Peru
— 4 nights
Fly + shuttle:  13​h
2
San Pedro de Atacama, Chile
— 2 nights
shuttle + Fly:  5​h
3
Santiago, Chile
— 4 nights
+2
Fly + taxi + shuttle:  8​h 30​min
4
Los Glaciares National Park, Argentina
— 1 night
bus:  6​h
5
El Chalten, Argentina
— 2 nights
+4
bus + taxi + Fly + taxi + bus:  8​h
6
Puerto Madryn, Argentina
— 1 night
Fly:  3​h 30​min
7
Buenos Aires, Argentina
— 4 nights
Fly:  3​h 30​min
8
Iguazu National Park, Argentina
— 2 nights
Fly:  2​h 15​min
9
Rio de Janeiro, Brazil
— 6 nights
+4
Fly + bus + foot + subway + bus:  7​h 15​min
10
Alto Paraiso de Goias, Brazil
— 4 nights
+3
bus + subway + bus + Fly:  10​h 45​min
11
Fernando de Noronha, Brazil
— 6 nights
Fly + shuttle:  3​h 30​min
12
Porto de Galinhas, Brazil
— 7 nights
shuttle + Fly:  21​h 15​min
End: Seattle, United States

4
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Satisfy your inner culture vulture at Sacsayhuaman and Centro Historico De Cusco. Take a break from the city and head to Salinas de Maras and exploor. There's lots more to do: steep yourself in history at Plaza de Armas, take in the architecture and atmosphere at Cusco Cathedral, take in the local highlights with Walking tours, and take an in-depth tour of Museo Inka.

To find ratings, photos, and more tourist information, use the Cusco holiday builder .

Seattle, USA to Cusco is an approximately 18-hour flight. The time zone difference when traveling from Seattle to Cusco is 3 hours. Expect somewhat warmer weather when traveling from Seattle in March: highs in Cusco hover around 68°F, while lows dip to 46°F. Finish your sightseeing early on the 6th (Fri) so you can travel to San Pedro de Atacama.

Things to do in Cusco

Historic Sites Tours Museums

Side Trips

Sacred Valley of the Incas, Salinas de Maras
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Salinas de Maras ©
Salinas de Maras
Centro Historico De Cusco ©
Centro Historico De Cusco

2
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Get in touch with nature at Atacama Desert and Geyser del Tatio. There's still lots to do: look for all kinds of wild species at Salar de Tara and explore the striking landscape at Valle De La Luna.

To see maps, photos, traveler tips, and tourist information, refer to the San Pedro de Atacama tour planning app .

Getting from Cusco to San Pedro de Atacama by combination of flight and bus takes about 13 hours. Other options: do a combination of flight and bus; or drive. The time zone difference when traveling from Cusco to San Pedro de Atacama is 1 hour. Expect a bit warmer weather when traveling from Cusco in March: highs in San Pedro de Atacama hover around 75°F, while lows dip to 43°F. Wrap up your sightseeing on the 9th (Mon) to allow time to travel to Santiago.

Things to do in San Pedro de Atacama

Parks Nature Wildlife

Side Trip

Atacama Desert
Highlights from your plan
Atacama Desert ©
Atacama Desert
Valle De La Luna ©
Valle De La Luna
Geyser del Tatio ©
Geyser del Tatio

4
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Get some cultural insight at Concha y Toro and La Chascona. Step out of the city life by going to San Cristóbal Hill and Ski Portillo. You'll find plenty of places to visit near Santiago: Emiliana Organic Vineyards (in Casablanca) and Odfjell Vineyards (in Padre Hurtado). And it doesn't end there: don't miss a visit to Santa Lucia Hill, admire the striking features of Metropolitan Cathedral (Catedral Metropolitana), explore the galleries of Centro Cultural Palacio de la Moneda y Plaza de la Ciudadania, and admire the masterpieces at Museo Chileno de Arte Precolombino.

To see traveler tips, ratings, other places to visit, and other tourist information, use the Santiago visit planning tool .

Getting from San Pedro de Atacama to Santiago by combination of shuttle and flight takes about 5 hours. Other options: drive; or take a bus. Cap off your sightseeing on the 13th (Fri) early enough to travel to Los Glaciares National Park.

Things to do in Santiago

Parks Wineries Winter Sports

Side Trips

Odfjell Vineyards, Concha y Toro, Ski Portillo, Emiliana Organic Vineyards
Highlights from your plan
San Cristóbal Hill ©
San Cristóbal Hill
Concha y Toro ©
Concha y Toro
Ski Portillo ©
Ski Portillo

1
night
Los Glaciares National Park, Argentina

Los Glaciares National Park ©
A World Heritage Site, Los Glaciares National Park contains a giant ice cap that feeds 47 vast glaciers.
Kick off your visit on the 14th (Sat): take in the dramatic natural features at Perito Moreno Glacier. On your second day here, stroll through Laguna de los Tres.

To see reviews, maps, more things to do, and other tourist information, read Los Glaciares National Park day trip planning site .

Getting from Santiago to Los Glaciares National Park by flight takes about 8.5 hours. Other options: do a combination of flight and bus; or do a combination of bus and flight. Due to the time zone difference, you'll lose 1 hour traveling from Santiago to Los Glaciares National Park. Expect a daytime high around 55°F in March, and nighttime lows around 53°F. Finish up your sightseeing early on the 15th (Sun) so you can catcht the bus to El Chalten.

Things to do in Los Glaciares National Park

Parks Nature Trails
Highlights from your plan
Perito Moreno Glacier ©
Perito Moreno Glacier

2
nights
El Chalten, Argentina

El Chalten ©
Nestled up against the hills of the Los Glaciares National Park, El Chalten serves as one of the nation's most bustling hubs for hikers and backpackers heading out into the wild landscape of southern Patagonia.
Start off your visit on the 16th (Mon): explore the striking landscape of Fitz Roy. Get ready for a full day of sightseeing on the next day: take your sightseeing to a higher altitude at Sendero Loma del Pliegue Tumbado and then contemplate the waterfront views at Laguna Torre.

For more things to do, where to stay, and more tourist information, you can read our El Chalten trip planner.

Take a bus from Los Glaciares National Park to El Chalten in 6 hours. Finish up your sightseeing early on the 17th (Tue) so you can travel to Puerto Madryn.

Things to do in El Chalten

Parks Nature Trails
Highlights from your plan
Fitz Roy ©
Fitz Roy
Laguna Torre ©
Laguna Torre
Sendero Loma del Pliegue Tumbado ©
Sendero Loma del Pliegue Tumbado

1
night
Puerto Madryn, Argentina

Puerto Madryn ©
Whales and penguins frolic in the waters of Puerto Madryn, one of Argentine Patagonia's most important port cities.
Start off your visit on the 18th (Wed): identify plant and animal life at Punta Tombo. Get ready for a full day of sightseeing on the next day: contemplate the waterfront views at Peninsula Valdes.

To find reviews, ratings, where to stay, and tourist information, use the Puerto Madryn trip itinerary site .

Do a combination of bus and flight from El Chalten to Puerto Madryn in 8 hours. Alternatively, you can drive; or take a bus. Wrap up your sightseeing on the 19th (Thu) to allow time to travel to Buenos Aires.

Things to do in Puerto Madryn

Parks Wildlife Nature

Side Trip

Punta Tombo
Highlights from your plan
Punta Tombo ©
Punta Tombo
Peninsula Valdes ©
Peninsula Valdes

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Do some cultural sightseeing at Puerto Madero and Parque 3 de Febrero. There's lots more to do: don't miss a visit to Cemiterio de Recoleta, get a sense of history and politics at Casa Rosada, explore the world behind art at Museo de Arte Latinoamericano de Buenos Aires, and shop like a local with Palermo.

To find where to stay, ratings, other places to visit, and tourist information, refer to the Buenos Aires trip maker site .

Getting from Puerto Madryn to Buenos Aires by flight takes about 3.5 hours. Other options: do a combination of bus and flight; or drive. March in Buenos Aires sees daily highs of 77°F and lows of 64°F at night. Finish up your sightseeing early on the 23rd (Mon) so you can travel to Iguazu National Park.

Things to do in Buenos Aires

Neighborhoods Historic Sites Shopping
Highlights from your plan
Puerto Madero ©
Puerto Madero
Parque 3 de Febrero ©
Parque 3 de Febrero
San Telmo ©
San Telmo

2
nights
Iguazu National Park, Argentina

Iguazu National Park ©
Iguazu National Park contains 672 sq km (259 sq mi) of fertile subtropical forests, but its main attraction is the majestic Iguazu Falls.
On the 24th (Tue), take in the dramatic scenery at Salto San Martin and then admire the sheer force of Iguazu Falls. On the 25th (Wed), you'll have a packed day of sightseeing: head off the coast to Isla San Martin and then admire the sheer force of Salto Bernabe Mendez.

To find photos, ratings, where to stay, and tourist information, you can read our Iguazu National Park trip planner.

You can fly from Buenos Aires to Iguazu National Park in 3.5 hours. Alternatively, you can drive; or take a bus. When traveling from Buenos Aires in March, plan for somewhat warmer days and about the same nights in Iguazu National Park: temperatures range from 85°F by day to 66°F at night. Finish your sightseeing early on the 25th (Wed) so you can travel to Rio de Janeiro.

Things to do in Iguazu National Park

Parks Nature Wildlife
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Salto Bernabe Mendez ©
Salto Bernabe Mendez
Salto San Martin ©
Salto San Martin

6
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Your cultural itinerary includes sights like Praia de Ipanema and Pao de Acucar. Take a break from the city and head to Copacabana Beach and Parque Nacional Tijuca. There's much more to do: pause for some photo ops at Corcovado Christ the Redeemer, enjoy the sand and surf at Praia de Grumari, stroll through Barra da Tijuca Beach, and take in nature's colorful creations at Theatro Municipal do Rio de Janeiro.

For ratings, more things to do, where to stay, and more tourist information, you can read our Rio de Janeiro online driving holiday planner .

You can fly from Iguazu National Park to Rio de Janeiro in 2.5 hours. Other options are to drive; or take a bus. Traveling from Iguazu National Park in March, you can expect nighttime temperatures to be a bit warmer in Rio de Janeiro, with lows of 74°F. Finish your sightseeing early on the 31st (Tue) to allow enough time to travel to Alto Paraiso de Goias.

Things to do in Rio de Janeiro

Parks Outdoors Nature
Highlights from your plan
Copacabana Beach ©
Copacabana Beach
Praia de Ipanema
Praia de Ipanema
Pao de Acucar ©
Pao de Acucar

4
nights
Alto Paraiso de Goias, Brazil

Alto Paraiso de Goias ©
Developed from a 19th-century cattle ranch, Alto Paraiso de Goias serves as the major gateway to a World Heritage-listed national park known for containing some of the world's oldest natural rock formations.
Escape the urban bustle at Parque Nacional da Chapada dos Veadeiros and Catarata dos Couros. There's much more to do: take in the dramatic scenery at Cachoeira Santa Barbara, witness a stunning natural landmark at Aguas Termais do Morro Vermelho, look for all kinds of wild species at Santuario Ecologico Vale Dourado, and trek along Sertao Zen.

To find traveler tips, other places to visit, ratings, and tourist information, refer to the Alto Paraiso de Goias online trip maker .

Traveling by combination of flight and bus from Rio de Janeiro to Alto Paraiso de Goias takes 7.5 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Rio de Janeiro to Alto Paraiso de Goias is minus 1 hour. Wrap up your sightseeing on the 4th (Sat) early enough to travel to Fernando de Noronha.

Things to do in Alto Paraiso de Goias

Parks Nature Wildlife

Side Trip

Chapada dos Veadeiros National Park
Highlights from your plan
Cachoeira do Segredo ©
Cachoeira do Segredo
Almecegas I Waterfalls ©
Almecegas I Waterfalls

6
nights
Fernando de Noronha, Brazil

Fernando de Noronha ©
With 21 lush islands scattered among pristine waters in the Atlantic Ocean, a Fernando de Noronha holiday is well worth the effort it takes to get there.
Take a break from the city and head to Shark Diving and Praia do Sueste. Get some cultural insight at Capela de Sao Pedro and Shark Museum. There's lots more to do: enjoy the sand and surf at Baia do Sancho, stroll through Praia do Bode, head outdoors with Baia dos Porcos, and see majestic marine mammals with a dolphin and whale watching tour.

For photos, more things to do, reviews, and tourist information, read our Fernando de Noronha trip itinerary planner.

You can do a combination of bus and flight from Alto Paraiso de Goias to Fernando de Noronha in 11 hours. Traveling from Alto Paraiso de Goias to Fernando de Noronha, you'll lose 2 hours due to the time zone difference. In April, daytime highs in Fernando de Noronha are 85°F, while nighttime lows are 77°F. Finish your sightseeing early on the 11th (Sat) to allow enough time to travel to Porto de Galinhas.

Things to do in Fernando de Noronha

Outdoors Parks Beaches
Highlights from your plan
Baia do Sancho ©
Baia do Sancho
Praia do Sueste ©
Praia do Sueste
Baia dos Porcos ©
Baia dos Porcos

7
nights
Porto de Galinhas, Brazil

Porto de Galinhas ©
You're in for a treat on your beach holiday to Porto de Galinha.
Do some cultural sightseeing at Outeiro church and panoramic view and Museu das Tartarugas - Ecoassociados. Take a break from the city and head to Muro Alto Beach and Vila de Porto de Galinhas Beach. Explore the numerous day-trip ideas around Porto de Galinhas: Piscinas Naturais de Barra Grande (in Barra Grande), Praia dos Carneiros (in Tamandare) and Gales de Maragogi (in Maragogi). Next up on the itinerary: explore the gorgeous colors at Piscinas Naturais de Porto de Galinhas, discover the deep blue sea with a scuba or snorkeling tour, look for gifts at Nata Artesanato, and sample the fine beverages at Cachacaria e Pimentaria Tio Gilson.

To see reviews, where to stay, other places to visit, and other tourist information, read Porto de Galinhas trip planning site .

Traveling by combination of flight and shuttle from Fernando de Noronha to Porto de Galinhas takes 3.5 hours. The time zone difference moving from Fernando de Noronha Time to Brasilia Time is minus 1 hour. In April, plan for daily highs up to 85°F, and evening lows to 76°F. Wrap up your sightseeing on the 18th (Sat) to allow time to travel back home.

Things to do in Porto de Galinhas

Parks Outdoors Beaches

Side Trips

Maragogi, Praia dos Carneiros
Highlights from your plan
Muro Alto Beach ©
Muro Alto Beach
Vila de Porto de Galinhas Beach ©
Vila de Porto de Galinhas Beach
Praia dos Carneiros ©
Praia dos Carneiros

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