48 days in South America Itinerary

48 days in South America Itinerary

Created using Inspirock South America trip maker

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Route & dates

48 days in South America Itinerary

Start: Manchester, United Kingdom
Fly:  17​h 45​min
1
Rio de Janeiro, Brazil
— 4 nights
Fly:  2​h
2
Brasilia, Brazil
— 1 night
Fly:  3​h 30​min
3
Sao Paulo, Brazil
— 4 nights
Fly:  6​h 45​min
4
Buenos Aires, Argentina
— 4 nights
Fly:  5​h 15​min
5
San Carlos de Bariloche, Argentina
— 5 nights
bus + Fly:  12​h
6
Punta Arenas, Chile
— 1 night
Fly:  5​h 45​min
7
Santiago, Chile
— 4 nights
Fly + shuttle:  5​h
8
San Pedro de Atacama, Chile
— 5 nights
Drive:  11​h 15​min
9
Uyuni, Bolivia
— 4 nights
taxi + Fly:  8​h 30​min
10
Cusco, Peru
— 5 nights
Fly:  7​h 15​min
11
San Andres Island, Colombia
— 3 nights
Fly:  3​h 15​min
12
Cartagena, Colombia
— 3 nights
Fly:  18​h 45​min
End: Manchester, United Kingdom

4
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
You'll explore the less-touristy side of things at Barra da Tijuca Beach and Morro Dois Irmaos. Head to BarraShopping and Centro Cultural Municipal Parque das Ruinasfor plenty of shopping. The adventure continues: take your sightseeing to a higher altitude at Pao de Acucar, enjoy the sand and surf at Praia de Ipanema, tour the pleasant surroundings at Praia de Grumari, and explore the galleries of Dom Quixote.

To find where to stay, ratings, reviews, and tourist information, use the Rio de Janeiro trip itinerary planner .

Manchester, UK to Rio de Janeiro is an approximately 18-hour flight. You can also do a combination of train and flight. The time zone changes from Greenwich Mean Time to Brasilia Time, which is usually a -3 hour difference. Prepare for warmer weather when traveling from Manchester in March: high temperatures in Rio de Janeiro hover around 36°C and lows are around 27°C. Finish your sightseeing early on the 19th (Thu) to allow enough time to travel to Brasilia.

Things to do in Rio de Janeiro

Parks Outdoors Beaches
Highlights from your plan
Copacabana Beach ©
Copacabana Beach
Praia de Ipanema
Praia de Ipanema
Bondinho  Pao de Acucar ©
Bondinho Pao de Acucar

1
night
Brasilia, Brazil

Brasilia ©
Although it lacks the cultural flair of Rio de Janeiro and the massive urban sprawl of Sao Paulo, Brasilia holds a fascinating place in the tapestry of Brazil.
Start off your visit on the 20th (Fri): pause for some serene contemplation at Igrejinha N.S. De Fatima church and then explore the striking landscape of Parque Nacional de Brasilia. Get ready for a full day of sightseeing on the 21st (Sat): stop by Parkshopping and then explore the striking landscape of Chapada Imperial.

To find other places to visit, photos, where to stay, and tourist information, refer to the Brasilia journey builder site .

Getting from Rio de Janeiro to Brasilia by flight takes about 2 hours. Other options: drive; or take a bus. Expect slightly colder temperatures when traveling from Rio de Janeiro in March; daily highs in Brasilia reach 32°C and lows reach 21°C. Wrap up your sightseeing on the 21st (Sat) early enough to travel to Sao Paulo.

Things to do in Brasilia

Parks Nature Wildlife

Side Trip

Chapada Imperial
Highlights from your plan
Chapada Imperial ©
Chapada Imperial
Parque Nacional de Brasilia ©
Parque Nacional de Brasilia
Igrejinha N.S. De Fatima church ©
Igrejinha N.S. De Fatima church

4
nights
Sao Paulo, Brazil

Sao Paulo ©
Don't let the city's nickname--"Land of Drizzle"--dampen your spirits during a trip to Sao Paulo.
Do your shopping at Paulista Avenue and Livraria Cultura. Deepen your sense of the past at sights like Fo Guang Shan Brazil - Zu Lai Temple and Temple of Solomon. Get out of town with these interesting Sao Paulo side-trips: Praia de Pernambuco (in Guaruja) and Praia Guarau (in Peruibe). There's lots more to do: admire the masterpieces at Museu do Som e Imagem - MIS, pick up some local products at Mercado Municipal de São Paulo, wander the streets of Batman Alley, and buy something for everyone on your list at Shopping JK Iguatemi.

To find reviews, where to stay, photos, and other tourist information, refer to the Sao Paulo trip itinerary planner .

Traveling by flight from Brasilia to Sao Paulo takes 3.5 hours. Alternatively, you can do a combination of flight and bus; or drive. In March, daytime highs in Sao Paulo are 32°C, while nighttime lows are 22°C. Cap off your sightseeing on the 25th (Wed) early enough to travel to Buenos Aires.

Things to do in Sao Paulo

Shopping Parks Beaches

Side Trips

Fo Guang Shan Brazil - Zu Lai Temple, Praia de Pernambuco, Praia Guarau
Highlights from your plan
Praia de Pernambuco ©
Praia de Pernambuco
Fo Guang Shan Brazil - Zu Lai Temple ©
Museu do Som e Imagem - MIS ©
Museu do Som e Imagem - MIS

4
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Satisfy your inner culture vulture at Puerto Madero and Basilica del Santisimo Sacramento. Escape the urban bustle at Horseback Riding Tours and Playa La Balandra. Change things up with these side-trips from Buenos Aires: Basilica de Lujan (in Lujan), San Isidro (Catedral de San Isidro & Villa Ocampo) and Reserva Natural Urbana (in Castelar). There's still lots to do: admire the natural beauty at Parque 3 de Febrero, wander the streets of San Telmo, and take in the architecture and atmosphere at Iglesia Inmaculada Concepcion.

To see traveler tips, more things to do, where to stay, and other tourist information, refer to the Buenos Aires travel route planner.

You can fly from Sao Paulo to Buenos Aires in 7 hours. Alternatively, you can do a combination of bus and flight; or drive. In March, plan for daily highs up to 29°C, and evening lows to 20°C. Cap off your sightseeing on the 29th (Sun) early enough to travel to San Carlos de Bariloche.

Things to do in Buenos Aires

Outdoors Parks Historic Sites

Side Trips

San Isidro, Reserva Natural Urbana, Basilica de Lujan, Playa La Balandra
Highlights from your plan
Puerto Madero ©
Puerto Madero
Catedral de San Isidro ©
Catedral de San Isidro
Basilica del Santisimo Sacramento ©
Basilica del Santisimo Sacramento

5
nights
San Carlos de Bariloche, Argentina

Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
Satisfy your inner culture vulture at Parroquia San Eduardo and Museo de la Patagonia. Take a break from the city and head to Parque Nacional Los Arrayanes and Kayaking & Canoeing. Go for a jaunt from San Carlos de Bariloche to Villa Traful to see Mirador Lago Traful about 1h 30 min away. And it doesn't end there: hike along Refugio Frey, hunt for treasures at Feria Artesanal Municipal, take your sightseeing to a higher altitude at Ventisquero Negro, and get a new perspective on things with Boat Tours & Water Sports.

Plan a trip to San Carlos de Bariloche easily and quickly by telling Inspirock to suggest an itinerary.

You can fly from Buenos Aires to San Carlos de Bariloche in 5.5 hours. Other options are to drive; or take a bus. Expect little chillier weather when traveling from Buenos Aires in March: highs in San Carlos de Bariloche hover around 23°C, while lows dip to 5°C. Wrap up your sightseeing on the 3rd (Fri) to allow time to travel to Punta Arenas.

Things to do in San Carlos de Bariloche

Parks Outdoors Nature

Side Trips

Mirador Lago Traful, Parque Nacional Los Arrayanes
Highlights from your plan
Kayaking & Canoeing
Fishing Charters & Tours
Parque Nacional Los Arrayanes ©
Parque Nacional Los Arrayanes

1
night
Punta Arenas, Chile

Punta Arenas ©
An erstwhile hub of the sheep wool industry, Punta Arenas has evolved into a gateway of sorts for hikers, cruise ship passengers, and adventure travelers heading out on the windswept lands of Chile's extreme southern reaches.
Kick off your visit on the 4th (Sat): explore the different monuments and memorials at Cementerio Municipal, then sample the tasty concoctions at Cerveceria Hernando de Magallanes, and then see majestic marine mammals with a dolphin and whale watching tour. On the 5th (Sun), you'll have a packed day of sightseeing: take in the exciting artwork at Centro Artesanal, browse the exhibits of La Galeria: Tienda de Arte y Diseno, and then look for all kinds of wild species at Reserva nacional Magallanes.

For more things to do, other places to visit, maps, and more tourist information, read Punta Arenas driving holiday planning app .

Do a combination of flight and bus from San Carlos de Bariloche to Punta Arenas in 12 hours. Alternatively, you can do a combination of flight, shuttle, and bus; or drive. Due to the time zone difference, you'll gain 1 hour traveling from San Carlos de Bariloche to Punta Arenas. While traveling from San Carlos de Bariloche, expect little chillier days and about the same nights in Punta Arenas, ranging from highs of 11°C to lows of 3°C. Wrap up your sightseeing on the 5th (Sun) early enough to travel to Santiago.

Things to do in Punta Arenas

Wildlife Tours Outdoors
Highlights from your plan
Cementerio Municipal ©
Cementerio Municipal
Reserva nacional Magallanes ©
Reserva nacional Magallanes
Dolphin & Whale Watching

4
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Get some cultural insight at Vina Santa Rita and San Francisco Church. You'll explore the less-touristy side of things at Vina Undurraga and Santuario de la Inmaculada Concepcion. Explore the numerous day-trip ideas around Santiago: Casablanca (Kingston Family Vineyards & Bodegas RE). There's much more to do: take your sightseeing to a higher altitude at San Cristóbal Hill, take a stroll through Barrio Italia, do a tasting at Santa Carolina, and shop like a local with Isidora Goyenechea.

Inspirock's itinerary builder makes planning a Santiago trip simple and quick.

Traveling by flight from Punta Arenas to Santiago takes 6 hours. Alternatively, you can drive; or take a bus. Finish your sightseeing early on the 9th (Thu) to allow enough time to travel to San Pedro de Atacama.

Things to do in Santiago

Wineries Neighborhoods Historic Sites

Side Trips

Casablanca, Vina Undurraga, Vina Santa Rita
Highlights from your plan
Vina Santa Rita ©
Vina Santa Rita
Vina Undurraga ©
Vina Undurraga

5
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Get some cultural insight at Pukara de Quitor and Cementerio de Toconao. You'll explore the less-touristy side of things at Piedras Rojas and Mirador de Kari, Piedra del Coyote. There's much more to do: look for all kinds of wild species at Valle Arcoiris, take in the local highlights with Walking tours, get curious at Museo del Meteorito, and get outside with Quebrada del Diablo.

For other places to visit, maps, traveler tips, and other tourist information, read San Pedro de Atacama itinerary planner .

Traveling by combination of flight and shuttle from Santiago to San Pedro de Atacama takes 5 hours. Alternatively, you can drive; or take a bus. In April, daily temperatures in San Pedro de Atacama can reach 28°C, while at night they dip to 4°C. Finish your sightseeing early on the 14th (Tue) so you can travel to Uyuni.

Things to do in San Pedro de Atacama

Parks Nature Tours

Side Trip

Cementerio de Toconao
Highlights from your plan
Piedras Rojas ©
Piedras Rojas
Valle Arcoiris ©
Valle Arcoiris
Valle De La Luna ©
Valle De La Luna

4
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Deepen your sense of the past at sights like Avenida Ferroviaria and Iglesia San Cristobal Lipez. Eschew the tourist crowds and head to Isla Incahuasi and Museo de la Llama y la Sal. There's much more to do: explore the striking landscape at Salar de Uyuni, capture your vacation like a pro with an inspiring photography tour, examine the collection at Necropolis & Museum Kawsay Wasy, and make a trip to Plaza Arce.

To find more things to do, traveler tips, and other tourist information, read Uyuni road trip site .

You can do a combination of bus and car from San Pedro de Atacama to Uyuni in 11.5 hours. Alternatively, you can drive; or do a combination of bus, car, and train. When traveling from San Pedro de Atacama in April, plan for cooler days and a bit warmer nights in Uyuni: temperatures range from 10°C by day to 9°C at night. Finish your sightseeing early on the 19th (Sun) to allow enough time to travel to Cusco.

Things to do in Uyuni

Parks Tours Outdoors

Side Trip

Museo de la Llama y la Sal
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi
Train Cemetery ©
Train Cemetery

5
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Step off the beaten path and head to Moray and Kayaking & Canoeing. Shop till you drop at Mercado Central de San Pedro and Centro de Textiles Tradicionales del Cusco. Explore Cusco's surroundings by going to Piquillacta (in Huarcapay) and San Pedro Apostol de Andahuaylillas (in Andahuaylillas). There's much more to do: contemplate the long history of Sacsayhuaman, identify plant and animal life at Santuario Animal de Cochahuasi, get a new perspective on things with Boat Tours & Water Sports, and indulge in some personalized pampering at some of the best spas.

Plan a trip to Cusco easily and quickly by telling Inspirock to suggest an itinerary.

Getting from Uyuni to Cusco by combination of car and flight takes about 8.5 hours. Other options: drive; or do a combination of car and bus. Traveling from Uyuni to Cusco, you'll gain 1 hour due to the time zone difference. When traveling from Uyuni in April, plan for a bit warmer days and about the same nights in Cusco: temperatures range from 23°C by day to 7°C at night. Cap off your sightseeing on the 24th (Fri) early enough to travel to San Andres Island.

Things to do in Cusco

Tours Outdoors Adventure

Side Trips

Piquillacta, Moray, San Pedro Apostol de Andahuaylillas
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Moray ©
Moray
exploor ©
exploor

3
nights
San Andres Island, Colombia

San Andres Island ©
The coral San Andres Island boasts a rich colonial history, exotic beaches, and a laidback, tropical lifestyle.
Eschew the tourist crowds and head to Cayo El Acuario and West View. Get some cultural insight at Primera Iglesia Bautista and Plaza Canon de Morgan. And it doesn't end there: discover the deep blue sea with a scuba or snorkeling tour, explore the striking landscape at Morgan's Head, stroll through Playa Charquitos, and identify plant and animal life at La Piscinita.

For maps, more things to do, ratings, and tourist information, read San Andres Island trip itinerary app .

Fly from Cusco to San Andres Island in 7.5 hours. Traveling from Cusco in April, expect nights in San Andres Island to be warmer, around 30°C, while days are a bit warmer, around 36°C. Finish your sightseeing early on the 27th (Mon) to allow enough time to travel to Cartagena.

Things to do in San Andres Island

Wildlife Parks Outdoors

Side Trip

Morgan's Head
Highlights from your plan
Cayo El Acuario ©
Cayo El Acuario
Scuba & Snorkeling
La Piscinita ©
La Piscinita

3
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Your inner history buff will appreciate Templo de Santo Domingo and Iglesia de Santo Toribio. Eschew the tourist crowds and head to Aviario Nacional de Colombia and Playa Blanca. And it doesn't end there: step into the grandiose world of Castillo de San Felipe de Barajas, look for gifts at Museo Del Cacao, get to know the fascinating history of Bairro Getsemani, and take a stroll through Centro Historico.

For reviews, traveler tips, where to stay, and tourist information, use the Cartagena trip planning tool .

You can fly from San Andres Island to Cartagena in 3.5 hours. April in Cartagena sees daily highs of 38°C and lows of 30°C at night. Wrap up your sightseeing on the 30th (Thu) to allow time to travel back home.

Things to do in Cartagena

Historic Sites Neighborhoods Parks

Side Trip

Isla Baru
Highlights from your plan
Aviario Nacional de Colombia ©
Aviario Nacional de Colombia
Templo de Santo Domingo ©
Templo de Santo Domingo
Castillo de San Felipe de Barajas ©
Castillo de San Felipe de Barajas

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