48 days in Bolivia, Los Andes & Santiago Itinerary

48 days in Bolivia, Los Andes & Santiago Itinerary

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1
Santa Cruz, Bolivia
— 3 nights
2
Sucre, Bolivia
— 5 nights
3
Cochabamba, Bolivia
— 3 nights
4
Trinidad, Bolivia
— 2 nights
5
Copacabana, Bolivia
— 2 nights
6
La Paz, Bolivia
— 6 nights
7
Potosi, Bolivia
— 3 nights
8
Tupiza, Bolivia
— 1 night
9
Uyuni, Bolivia
— 4 nights
10
Los Andes, Chile
— 7 nights
11
Santiago, Chile
— 10 nights

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3
nights
Santa Cruz, Bolivia

Santa Cruz ©
More populous than the capital and La Paz, and one of the fastest-growing cities in the world, Santa Cruz has become a thriving commercial center, yet retained some of the trappings of tradition.
Get some cultural insight at Fuerte de Samaipata and Parroquia La Santa Cruz. You'll discover tucked-away gems like Noel Kempff Mercado National Park and Plaza 24 de Septiembre. And it doesn't end there: contemplate in the serene atmosphere at Catedral de Santa Cruz, browse the different shops at Ventura mall, take a stroll around Casa Cultural Melchor Pinto, and take in nature's colorful creations at Guembe.

To see traveler tips, maps, other places to visit, and other tourist information, refer to the Santa Cruz online vacation planner.

Rio de Janeiro, Brazil to Santa Cruz is an approximately 7.5-hour flight. You can also drive; or take a bus. The time zone difference when traveling from Rio de Janeiro to Santa Cruz is minus 1 hour. In December, plan for daily highs up to 36°C, and evening lows to 26°C. Finish your sightseeing early on the 18th (Fri) to allow enough time to travel to Sucre.

Things to do in Santa Cruz

Parks · Historic Sites · Nature · Shopping

Side Trip

Highlights from your trip
©
World heritage site
Noel Kempff Mercado National Park
3.2
©
World heritage site
Fuerte de Samaipata
4.4
©
Religious Site
Catedral de Santa Cruz
4.4

5
nights
Sucre, Bolivia

Sucre ©

City of the Four Names

The constitutional capital of Bolivia, Sucre has a well-preserved historic center, with many buildings dating back to the city's founding in the 16th century.
Church of San Felipe Neri (Oratorio de San Felipe de Neri) and La Recoleta are good opportunities to explore the local culture. Take a break from the city and head to La Maja and Climbing Tours. There's much more to do: explore the world behind art at Museum of Indigenous Art ASUR, view the masterpieces at Arte y Cultura Sucre Galeria, stop by Inca Pallay Shop, and don't miss a visit to Centro Cultural Masis.

For reviews, photos, and other tourist information, refer to the Sucre trip itinerary planner.

Traveling by flight from Santa Cruz to Sucre takes 2.5 hours. Alternatively, you can drive; or take a bus. When traveling from Santa Cruz in December, plan for a bit cooler days in Sucre, with highs around 26°C, while nights are colder with lows around 11°C. On the 23rd (Wed), wrap the sightseeing up by early afternoon so you can travel to Cochabamba.

Things to do in Sucre

Historic Sites · Museums · Outdoors · Tours
Highlights from your trip
©
Religious Site
La Recoleta
4.3
©
Science Museum
Museo del Tesoro
4.6

3
nights
Cochabamba, Bolivia

Cochabamba ©

City of Eternal Spring

Dynamic and friendly, Cochabamba benefits from a mild climate largely responsible for its Mediterranean lifestyle and nickname the "City of Eternal Spring." An ideal alternative for anyone wishing to escape the chaos of South America's more popular destinations, Cochabamba vacations allow visitors to discover how regular Bolivians live on an everyday basis.
Get in touch with nature at Parque de las Aves Agroflori and Tunari. You'll explore the less-touristy side of things at El Cristo de la Concordia and Convento Museo Santa Teresa. Next up on the itinerary: add some entertainment to your itinerary with Proyecto Martadero, appreciate the views at Valle Alto, head outdoors with andesXtremo, and steep yourself in history at Palacio Portales.

To see maps, reviews, traveler tips, and more tourist information, go to the Cochabamba route app.

You can fly from Sucre to Cochabamba in 2.5 hours. Other options are to drive; or take a bus. Traveling from Sucre in December, expect nights in Cochabamba to be about the same, around 15°C, while days are somewhat warmer, around 32°C. Wrap up your sightseeing on the 26th (Sat) to allow time to fly to Trinidad.

Things to do in Cochabamba

Parks · Nature · Historic Sites · Outdoors
Highlights from your trip
©
Mountain
Tunari
4.7
©
Performance
Proyecto Martadero
4.4

2
nights
Trinidad, Bolivia

Trinidad ©
Trinidad, officially La Santísima Trinidad, is a city in Bolivia, capital of the department of Beni. Kick off your visit on the 27th (Sun): stroll through Barba Azul Reserve. On the 28th (Mon), you'll have a packed day of sightseeing: don't miss a visit to Templo Misional Jesuitico de San Javier and then tour the pleasant surroundings at Bolivian Parrots Conservation.

To find ratings, reviews, maps, and other tourist information, read Trinidad trip maker tool.

You can fly from Cochabamba to Trinidad in 2.5 hours. Alternatively, you can drive; or take a bus. Prepare for a bit warmer weather when traveling from Cochabamba in December: high temperatures in Trinidad hover around 37°C and lows are around 26°C. Finish up your sightseeing early on the 28th (Mon) so you can travel to Copacabana.

Things to do in Trinidad

Wildlife · Parks

Side Trip

Highlights from your trip
©
Nature / Park
Barba Azul Reserve
5.0

2
nights
Copacabana, Bolivia

Copacabana ©
The town of Copacabana represents the largest Bolivian settlement on the shore of Lake Titicaca, the largest lake in the continent.
On the 29th (Tue), take in the spiritual surroundings of Basilica of Our Lady of Copacabana and then contemplate the waterfront views at Lake Titicaca. On the 30th (Wed), you'll have a packed day of sightseeing: take in the spiritual surroundings of Cerro Calvario and then trek along Isla del Sol.

To see other places to visit, where to stay, ratings, and tourist information, read Copacabana online itinerary planner.

Getting from Trinidad to Copacabana by combination of flight and bus takes about 6 hours. Other options: drive; or take a bus. Finish your sightseeing early on the 30th (Wed) so you can drive to La Paz.

Things to do in Copacabana

Historic Sites · Nature · Parks · Trails
Highlights from your trip
©
Hiking Trail
Isla del Sol
4.1
©
Religious Site
Cerro Calvario
4.4

6
nights
La Paz, Bolivia

La Paz ©

City that Touches the Sky

Take a moment to catch your breath as you commence your holiday in La Paz.
Step out of the city life by going to Chacaltaya Ski Resort and Adrenaline & Extreme Tours. Satisfy your inner culture vulture at Tiwanaku and Iglesia de San Francisco. Take a break from La Paz with a short trip to Huayna Potosi in Milluni, about 1h 20 min away. Spend the 31st (Thu) exploring the striking scenery along WMDR Yungas Road. There's still lots to do: take some stellar pictures from Mirador Killi Killi, see the interesting displays at National Museum of Ethnography and Folklore, get the lay of the land with Walking tours, and explore the striking landscape at Valley of the Moon.

For maps, more things to do, other places to visit, and tourist information, you can read our La Paz day trip website.

Drive from Copacabana to La Paz in 3.5 hours. Alternatively, you can take a bus. Expect a daytime high around 18°C in December, and nighttime lows around 3°C. Finish up your sightseeing early on the 5th (Tue) so you can travel to Potosi.

Things to do in La Paz

Outdoors · Tours · Parks · Nature

Side Trips

Highlights from your trip
©
Scenic Drive
WMDR Yungas Road
4.5
©
Mountain
Huayna Potosi
4.8

3
nights
Potosi, Bolivia

Potosi ©

Ville Imperial

One of the highest cities in the world at 4,090 m (13,420 ft), Potosi actually rose to fame for something below the ground.
Cerro Rico and Gruta De Las Galaxias are good opportunities to explore the local culture. You'll discover tucked-away gems like Casa Nacional de la Moneda and San Francisco of Potosi Convent and Temple. The adventure continues: contemplate in the serene atmosphere at San Lorenzo Church and contemplate the long history of Santa Teresa Convent Museum - Convento Museo Santa Teresa.

To find where to stay, maps, ratings, and tourist information, read Potosi online driving holiday planner.

You can do a combination of flight and car from La Paz to Potosi in 5.5 hours. Other options are to take a bus; or drive. In January, daily temperatures in Potosi can reach 17°C, while at night they dip to 3°C. Finish your sightseeing early on the 8th (Fri) to allow enough time to drive to Tupiza.

Things to do in Potosi

Historic Sites · Museums · Outdoors
Highlights from your trip
©
Historic Site
Cerro Rico
4.2
©
Specialty Museum
Casa Nacional de la Moneda
3.8

1
night
Tupiza, Bolivia

The southwestern mining town of Tupiza, near the Argentine border, reminisces of the wild west, and is supposedly the place where Butch Cassidy and the Sundance Kid faced their demise after a long string of bank robberies.
Kick off your visit on the 9th (Sat): see Off-Road Tours.

To find reviews, other places to visit, where to stay, and more tourist information, refer to the Tupiza trip itinerary builder tool.

Traveling by car from Potosi to Tupiza takes 4 hours. Alternatively, you can take a bus. Finish up your sightseeing early on the 9th (Sat) so you can go by car to Uyuni.

Things to do in Tupiza

Outdoors · Tours
Highlights from your trip
©
Off-Road Tour
Off-Road Tours
4.5

4
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Do some cultural sightseeing at Train Cemetery and Museo de la Llama y la Sal. Explore hidden gems such as Nature & Wildlife Tours and Museo Arquecologia y Antropologico de los Andes Meridionales. The adventure continues: step off the mainland to explore Isla Incahuasi, contemplate the geological forces at Tunupa Volcano, and explore the striking landscape at Salar de Uyuni.

To find photos, traveler tips, maps, and more tourist information, use the Uyuni planning tool.

You can drive from Tupiza to Uyuni in 4 hours. Other options are to take a bus; or take a train. In January, plan for daily highs up to 15°C, and evening lows to 13°C. Finish your sightseeing early on the 13th (Wed) to allow enough time to travel to Los Andes.

Things to do in Uyuni

Nature · Parks · Museums · Outdoors

Side Trip

Highlights from your trip
©
Must see
Salar de Uyuni
4.9
©
Island
Isla Incahuasi
4.6
©
Nature / Wildlife Tour
Nature & Wildlife Tours
3.7

7
nights
Los Andes, Chile

Los Andes ©
Los Andes, founded in July 31, 1791 as Santa Rosa de Los Andes, is a Chilean city and commune located in the province of the same name, in Valparaíso Region ("Fifth Region" of Chile). Step out of the city life by going to Playa de Zapallar and La Rambla. You'll get in some beach time at Playa Luna and Playa El Chungungo. Venture out of the city with trips to Portillo (Laguna del Inca & Ski Portillo Just For The Day), Playa Los Molles (in La Ligua) and Parque Escultorico Cementerio de Carretas (in Putaendo). The adventure continues: kick back and relax at Playa El Abanico, learn about winemaking at Vina San Esteban, tour the pleasant surroundings at Playa Chica, and visit Plaza de Armas de San Felipe.

For other places to visit, maps, reviews, and more tourist information, go to the Los Andes online road trip planner.

Use the Route module to find suitable travel options from Uyuni to Los Andes. When traveling from Uyuni in January, plan for much hotter days in Los Andes, with highs around 36°C, while nights are about the same with lows around 17°C. Cap off your sightseeing on the 21st (Thu) early enough to go by car to Santiago.

Things to do in Los Andes

Parks · Outdoors · Beaches · Wineries

Side Trips

Highlights from your trip

10
nights
Santiago, Chile

Santiago ©

City of the Island Hills

Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
You'll explore the less-touristy side of things at Colchagua Museum and Bodegas RE. Get in touch with nature at San Cristóbal Hill and Reserva Nacional Lago Penuelas. You'll find plenty of places to visit near Santiago: Vina del Mar (Moai & Corporacion Museo de Arqueologia e Historia Francisco Fonck), Kingston Family Vineyards (in Casablanca) and Vina Santa Rita (in Buin). Next up on the itinerary: learn about winemaking at Vina Undurraga, examine the collection at Casa de Isla Negra, get great views at Paseo Yugoslavo, and explore the world behind art at Palacio Baburizza.

To see other places to visit, photos, reviews, and more tourist information, use the Santiago trip itinerary planning app.

Traveling by car from Los Andes to Santiago takes 1.5 hours. Wrap up your sightseeing on the 31st (Sun) to allow time to travel back home.

Things to do in Santiago

Parks · Wildlife · Wineries · Museums

Side Trips

Highlights from your trip
©
Must see
Colchagua Museum
4.8
©
Winery / Vineyard
Vina Santa Rita
4.5

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