46 days in South America Itinerary

46 days in South America Itinerary

Created using Inspirock South America itinerary planner

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Route & dates

46 days in South America Itinerary

Start: Lisbon, Portugal
Fly:  26​h
1
Rio de Janeiro, Brazil
— 3 nights
+2
bus + foot + ferry:  4​h
2
Ilha Grande, Brazil
— 2 nights
+2
ferry + foot + bus:  4​h
3
Rio de Janeiro, Brazil
— 2 nights
Fly:  7​h
4
Bonito, Brazil
— 3 nights
shuttle:  31​h
5
Puerto Iguazu, Argentina
— 2 nights
Drive:  3​h 30​min
6
San Ignacio, Argentina
— Few hours
Drive + Fly:  11​h 30​min
7
Buenos Aires, Argentina
— 3 nights
bus:  7​h 30​min
8
Cordoba, Argentina
— 1 night
bus:  5​h 45​min
9
San Miguel de Tucuman, Argentina
— 1 night
bus:  7​h 30​min
10
Cafayate, Argentina
— 1 night
bus:  12​h 45​min
11
Salta, Argentina
— 2 nights
bus:  10​h
12
San Pedro de Atacama, Chile
— 2 nights
bus + Drive:  11​h 15​min
13
Uyuni, Bolivia
— 3 nights
taxi + Fly:  5​h 15​min
14
Sucre, Bolivia
— 1 night
bus:  18​h 15​min
15
Samaipata, Bolivia
— 2 nights
+3
bus + taxi + bus + Fly:  6​h 15​min
16
Cochabamba, Bolivia
— 1 night
bus:  10​h
17
Copacabana, Bolivia
— 2 nights
Drive + Fly:  9​h 15​min
18
Lima, Peru
— 1 night
bus:  4​h
19
Ica, Peru
— 1 night
bus:  5​h 30​min
20
Ayacucho, Peru
— 2 nights
Fly:  3​h 30​min
21
Cusco, Peru
— 1 night
+2
bus + foot + train:  3​h 15​min
22
Machu Picchu, Peru
— 4 nights
+2
train + foot + bus:  3​h 15​min
23
Cusco, Peru
— 1 night
End: Cusco, Peru

3
nights
Rio de Janeiro, Brazil

Rio de Janeiro
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
On the next day, don't miss a visit to Escadaria Selaron, take in the architecture and atmosphere at The Metropolitan Cathedral of Saint Sebastian, then tour the pleasant surroundings at Pedra do Arpoador, then enjoy the sand and surf at Praia de Ipanema, and finally tour the pleasant surroundings at Copacabana Beach.

To see ratings, maps, photos, and more tourist information, you can read our Rio de Janeiro trip itinerary planning site .

Lisbon, Portugal to Rio de Janeiro is an approximately 13.5-hour flight. You can also do a combination of flight and bus. The time zone difference moving from Western European Time (WET) to Brasilia Time (BRT) is minus 3 hours. In October, Rio de Janeiro is somewhat warmer than Lisbon - with highs of 32°C and lows of 24°C. You will have some time to spend on the 12th (Sat) before leaving for Ilha Grande.

Things to do in Rio de Janeiro

Beaches Outdoors Parks
Highlights from your plan
Praia de Ipanema
Praia de Ipanema
Copacabana Beach ©
Copacabana Beach
Barra da Tijuca Beach ©
Barra da Tijuca Beach

2
nights
Ilha Grande, Brazil

Ilha Grande ©
A tumultuous and unsavory history has kept Ilha Grande relatively undeveloped and free of the trappings of the modern world.
Start off your visit on the 12th (Sat): delve into the distant past at Aqueduto, visit a coastal fixture at Castelhanos Lighthouse, and then tour the pleasant surroundings at Dois Rios Beach. Keep things going the next day: enjoy the sand and surf at Aventureiro and then tour the pleasant surroundings at Lagoa Azul.

To find more things to do, reviews, ratings, and other tourist information, go to the Ilha Grande vacation maker site .

Traveling by combination of bus and ferry from Rio de Janeiro to Ilha Grande takes 4 hours. Expect a daytime high around 33°C in October, and nighttime lows around 23°C. You'll have a few hours on the 14th (Mon) to wrap things up before traveling to Rio de Janeiro.

Things to do in Ilha Grande

Beaches Outdoors Parks
Highlights from your plan
Dois Rios Beach ©
Dois Rios Beach
Lagoa Azul ©
Lagoa Azul
Aventureiro ©
Aventureiro

2
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
You've now added Parque Nacional Tijuca to your itinerary. Start off your visit on the 14th (Mon): take a peaceful walk through Parque Nacional Tijuca and then take in the spiritual surroundings of Jerusalem Cultural Center. On your second day here, take in the awesome beauty at Pao de Acucar, contemplate the long history of Parque Lage, then take in nature's colorful creations at Jardim Botânico do Rio de Janeiro, and finally admire the landmark architecture of Carioca Aqueduct.

For where to stay, more things to do, reviews, and other tourist information, refer to the Rio de Janeiro online trip planner .

Traveling by combination of ferry and bus from Ilha Grande to Rio de Janeiro takes 4 hours. You'll have a few hours on the 16th (Wed) to wrap things up before traveling to Bonito.

Things to do in Rio de Janeiro

Parks Nature Historic Sites
Highlights from your plan
Pao de Acucar ©
Pao de Acucar
Parque Lage ©
Parque Lage

3
nights
Bonito, Brazil

Bonito ©
A popular hub of ecotourism, Bonito offers plenty of attractions and activities for visitors in search of an adventurous, nature-filled holiday in Brazil.
Kick off your visit on the 16th (Wed): observe the fascinating underwater world at Aquario de Bonito and then get up close and personal with brilliant marine life at Aquario Natural. On the 17th (Thu), you'll have a packed day of sightseeing: contemplate the waterfront views at Rio Sucuri and then kick back and relax at Figueira Beach.

To see other places to visit, where to stay, ratings, and more tourist information, you can read our Bonito online holiday planner .

Getting from Rio de Janeiro to Bonito by flight takes about 4.5 hours. Other options: drive; or take a bus. The time zone difference when traveling from Rio de Janeiro to Bonito is minus 1 hour. You will have some time to spend on the 19th (Sat) before leaving for Puerto Iguazu.

Things to do in Bonito

Parks Nature Beaches
Highlights from your plan
Aquario Natural ©
Aquario Natural
Gruta Sao Mateus ©
Gruta Sao Mateus
Casa da memoria Raida ©
Casa da memoria Raida

2
nights
Puerto Iguazu, Argentina

Puerto Iguazu ©
The gateway to a national park inscribed on the World Heritage List, growing Puerto Iguazu sits on the confluence of two major rivers near the border with Paraguay and Brazil.
Get ready for a full day of sightseeing on the 21st (Mon): explore the wealth of natural beauty at Parque Nacional Iguazu, pause for some serene contemplation at Catedral Virgen del Carmen, and then take a stroll through Puerto Iguazu.

For ratings, maps, reviews, and more tourist information, you can read our Puerto Iguazu trip planner .

Do a combination of shuttle and flight from Bonito to Puerto Iguazu in 9 hours. Alternatively, you can drive; or take a shuttle. Traveling from Bonito to Puerto Iguazu, you'll lose 1 hour due to the time zone difference. October in Puerto Iguazu sees daily highs of 34°C and lows of 20°C at night. You'll have a few hours on the 22nd (Tue) to wrap things up before traveling to San Ignacio.

Things to do in Puerto Iguazu

Nature Parks Neighborhoods
Highlights from your plan
Puerto Iguazu ©
Puerto Iguazu
Catedral Virgen del Carmen ©
Catedral Virgen del Carmen

few
hours
San Ignacio, Argentina

San Ignacio ©
Tourists flock to the small Misiones town of San Ignacio for its most famous attraction, the restored ruins of a Jesuit settlement designed to house indigenous people.
On the 22nd (Tue), don't miss a visit to Ruina de Santa Ana, then contemplate the long history of Horacio Quiroga Home, and then explore the ancient world of Ruinas de San Ignacio.

Before you visit San Ignacio, use our trip planner to discover what you can do and see there.

Drive from Puerto Iguazu to San Ignacio in 3.5 hours. Traveling from Puerto Iguazu to San Ignacio, you'll gain 1 hour due to the time zone difference. In October, daytime highs in San Ignacio are 33°C, while nighttime lows are 20°C. Cap off your sightseeing on the 22nd (Tue) early enough to travel to Buenos Aires.

Things to do in San Ignacio

Historic Sites

Side Trip

Ruina de Santa Ana
Highlights from your plan
Ruinas de San Ignacio ©
Ruinas de San Ignacio
Horacio Quiroga Home ©
Horacio Quiroga Home
Ruina de Santa Ana ©
Ruina de Santa Ana

3
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires Free Tour has been added to your itinerary. San Telmo and Palacio de Aguas Corrientes will appeal to history buffs. Do some cultural sightseeing at Puerto Madero and Parque 3 de Febrero. And it doesn't end there: explore the world behind art at Museo Nacional de Bellas Artes, admire the natural beauty at Jardin Japones, admire the striking features of El Ateneo Grand Splendid, and wander the streets of La Boca.

To find photos, maps, ratings, and more tourist information, read our Buenos Aires driving holiday planner .

Explore your travel options from San Ignacio to Buenos Aires with the Route module. The time zone difference when traveling from San Ignacio to Buenos Aires is 1 hour. Traveling from San Ignacio in October, expect Buenos Aires to be little chillier, temps between 24°C and 17°C. Wrap up your sightseeing by early afternoon on the 26th (Sat) to allow time for travel to Cordoba.

Things to do in Buenos Aires

Neighborhoods Historic Sites Museums
Highlights from your plan
Puerto Madero ©
Puerto Madero
Parque 3 de Febrero ©
Parque 3 de Febrero
San Telmo ©
San Telmo

1
night
Cordoba, Argentina

Cordoba ©
History lives on in the streets of Cordoba, Argentina's second-largest city.
Planning Cordoba trip won't be overwheling when you use's Insprock itinerary maker.

Getting from Buenos Aires to Cordoba by flight takes about 3.5 hours. Other options: drive; or take a bus. Traveling from Buenos Aires in October, expect nights in Cordoba to be about the same, around 19°C, while days are a bit cooler, around 20°C. Wrap up your sightseeing on the 27th (Sun) early enough to travel to San Miguel de Tucuman.

Things to do in Cordoba

Historic Sites
Highlights from your plan
Paseo del Buen Pastor ©
Paseo del Buen Pastor
Iglesia de Los Capuchinos ©
Iglesia de Los Capuchinos
Iglesia Catedral de Córdoba ©
Iglesia Catedral de Córdoba

1
night
San Miguel de Tucuman, Argentina

San Miguel de Tucuman ©
The commercial hub of an area known for its high production of sugarcane, tobacco, and rice, San Miguel de Tucuman also has a historical claim to fame, having hosted the national congress that declared independence from Spain in 1816.
For traveler tips, other places to visit, reviews, and other tourist information, use the San Miguel de Tucuman trip itinerary builder site .

You can fly from Cordoba to San Miguel de Tucuman in 3 hours. Alternatively, you can take a bus; or drive. Traveling from Cordoba in October, expect nights in San Miguel de Tucuman to be about the same, around 18°C, while days are a bit warmer, around 33°C. Wrap up your sightseeing on the 28th (Mon) to allow time to drive to Cafayate.

Things to do in San Miguel de Tucuman

Historic Sites Museums
Highlights from your plan
Parroquia San Francisco ©
Parroquia San Francisco
Casa Historica de Tucuman ©
Casa Historica de Tucuman

1
night
Cafayate, Argentina

Cafayate
Nestled in one of the country's major wine regions, Cafayate and the surrounding area remain a top vacation destination throughout the year.
For ratings, where to stay, and more tourist information, you can read our Cafayate trip builder site .

Getting from San Miguel de Tucuman to Cafayate by car takes about 3.5 hours. Other options: take a bus. On the 29th (Tue), you'll have the morning to explore before heading off to Salta.

Things to do in Cafayate

Parks Nature Wineries

2
nights
Salta, Argentina

Salta ©
Salta boasts a vibrant social life and array of informative museums appealing to visitors looking for a memorable cultural experience.
You've now added Train to the Clouds to your itinerary.

To find reviews, other places to visit, where to stay, and tourist information, go to the Salta sightseeing planner .

Drive from Cafayate to Salta in 3 hours. Alternatively, you can do a combination of taxi and flight; or take a bus. In October, daily temperatures in Salta can reach 30°C, while at night they dip to 13°C. You will have some time to spend on the 31st (Thu) before leaving for San Pedro de Atacama.

Things to do in Salta

Tours Historic Sites Museums
Highlights from your plan
Train to the Clouds ©
Train to the Clouds
San Bernardo Convent ©
San Bernardo Convent

2
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
For photos, more things to do, and other tourist information, use the San Pedro de Atacama trip planning website .

Drive from Salta to San Pedro de Atacama in 8.5 hours. Alternatively, you can take a bus. The time zone difference moving from Argentine Time (ART) to Chile Time (CLT) is minus 1 hour. Traveling from Salta in October, you can expect nighttime temperatures to be little chillier in San Pedro de Atacama, with lows of 3°C. You will have some time to spend on the 2nd (Sat) before leaving for Uyuni.

Things to do in San Pedro de Atacama

Nature Parks Museums
Highlights from your plan
Geyser del Tatio ©
Geyser del Tatio
Father Le Paige Museum ©
Father Le Paige Museum
Museo del Meteorito ©
Museo del Meteorito

3
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Do some cultural sightseeing at Train Cemetery and Iglesia San Cristobal Lipez. And it doesn't end there: explore the striking landscape at Salar de Uyuni, step off the mainland to explore Isla Incahuasi, contemplate the geological forces at Tunupa Volcano, and don't miss a visit to Plaza Arce.

To see traveler tips, maps, more things to do, and more tourist information, refer to the Uyuni online driving holiday planner .

Traveling by combination of bus and car from San Pedro de Atacama to Uyuni takes 11.5 hours. Alternatively, you can drive; or do a combination of bus, car, and train. While traveling from San Pedro de Atacama, expect cooler days and a bit warmer nights in Uyuni, ranging from highs of 12°C to lows of 11°C. Finish up your sightseeing early on the 5th (Tue) so you can travel to Sucre.

Things to do in Uyuni

Nature Parks Museums
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Train Cemetery ©
Train Cemetery
Iglesia San Cristobal Lipez ©
Iglesia San Cristobal Lipez

1
night
Sucre, Bolivia

Sucre
The constitutional capital of Bolivia, Sucre has a well-preserved historic center, with many buildings dating back to the city's founding in the 16th century.
To find where to stay, photos, reviews, and other tourist information, you can read our Sucre planning site .

Getting from Potosi to Sucre by car takes about 2.5 hours. Other options: take a bus; or take a train. Expect somewhat warmer temperatures when traveling from Potosi in November; daily highs in Sucre reach 26°C and lows reach 11°C. On the 8th (Fri), you're off toSamaipata.

Things to do in Sucre

Tours Outdoors Classes

2
nights
Samaipata, Bolivia

Samaipata ©
Some who come for a holiday in Samaipata fall so head over heels that they never leave.
On the 8th (Fri), you'll have a packed day of sightseeing: learn about winemaking at Bodegas Landsua, then explore the ancient world of Fuerte de Samaipata, and then trek along Che Guevara Trail.

To see photos, ratings, and tourist information, you can read our Samaipata trip itinerary maker tool .

Getting from Sucre to Samaipata by combination of flight and bus takes about 6.5 hours. Other options: drive; or take a bus. Finish your sightseeing early on the 9th (Sat) to allow enough time to travel to Cochabamba.

Things to do in Samaipata

Outdoors Trails Parks
Highlights from your plan
Che Guevara Trail ©
Che Guevara Trail
Fuerte de Samaipata ©
Fuerte de Samaipata
Bodegas Landsua ©
Bodegas Landsua

1
night
Cochabamba, Bolivia

Cochabamba
Dynamic and friendly, Cochabamba benefits from a mild climate largely responsible for its Mediterranean lifestyle and nickname the "City of Eternal Spring." An ideal alternative for anyone wishing to escape the chaos of South America's more popular destinations, Cochabamba vacations allow visitors to discover how regular Bolivians live on an everyday basis.
To find traveler tips, reviews, more things to do, and tourist information, read Cochabamba trip itinerary planning site .

Getting from Samaipata to Cochabamba by combination of bus and flight takes about 6.5 hours. Other options: drive; or do a combination of car and flight. Expect a daytime high around 34°C in November, and nighttime lows around 14°C. You will leave for Copacabana on the 10th (Sun).

Things to do in Cochabamba

Parks Nature Outdoors

2
nights
Copacabana, Bolivia

Copacabana ©
The town of Copacabana represents the largest Bolivian settlement on the shore of Lake Titicaca, the largest lake in the continent.
Start off your visit on the 10th (Sun): step off the mainland to explore Isla del Sol. Keep things going the next day: contemplate the waterfront views at Lake Titicaca.

To find more things to do, other places to visit, photos, and tourist information, go to the Copacabana journey builder website .

Traveling by combination of flight and bus from Cochabamba to Copacabana takes 5 hours. Alternatively, you can drive; or take a bus. On the 12th (Tue), you'll have the morning to explore before heading off to Lima.

Things to do in Copacabana

Nature Parks Historic Sites
Highlights from your plan
Isla del Sol ©
Isla del Sol
Basilica of Our Lady of Copacabana
Basilica of Our Lady of Copacabana
Lake Titicaca ©
Lake Titicaca

1
night
Lima, Peru

Lima
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
To find out how to plan a trip to Lima, use our trip itinerary maker.

The Route module can help you plan travel from Copacabana to Lima. The time zone difference moving from Bolivia Time to Peru Time is minus 1 hour. In November, plan for daily highs up to 26°C, and evening lows to 20°C. On the 13th (Wed), you're off toIca.

Things to do in Lima

Tours Outdoors Nightlife

1
night
Ica, Peru

Ica ©
Located on the Ica River in the desert areas of Peru's southern coast, the city of Ica stands as something of an oasis in the dry, barren landscape.
Oasis of Huacachina has been added to your itinerary. On the 13th (Wed), examine the collection at Regional Museum of Ica, contemplate the waterfront views at Oasis of Huacachina, and then contemplate in the serene atmosphere at Santuario del Senor de Luren.

To see other places to visit, maps, traveler tips, and more tourist information, read our Ica visit planner .

Traveling by bus from Lima to Ica takes 4 hours. Alternatively, you can drive. November in Ica sees daily highs of 26°C and lows of 17°C at night. On the 14th (Thu), you'll have the morning to explore before heading off to Ayacucho.

Things to do in Ica

Nature Parks Historic Sites
Highlights from your plan
Santuario del Senor de Luren ©
Santuario del Senor de Luren
Regional Museum of Ica
Regional Museum of Ica

2
nights
Ayacucho, Peru

Ayacucho ©
Ayacucho remains best known for its 33 churches, with one to represent each year of Jesus' life.
Kick off your visit on the 14th (Thu): make a trip to Mirador turistico de Acuchimay.

For maps, more things to do, other places to visit, and other tourist information, go to the Ayacucho trip site .

Take a bus from Ica to Ayacucho in 5.5 hours. Alternatively, you can drive. While traveling from Ica, expect a bit warmer days and little chillier nights in Ayacucho, ranging from highs of 31°C to lows of 13°C. Wrap up your sightseeing on the 16th (Sat) early enough to travel to Cusco.

Things to do in Ayacucho

Historic Sites
Highlights from your plan
Basilica Catedral de Ayacucho ©
Basilica Catedral de Ayacucho
Plaza Mayor de Ayacucho ©
Plaza Mayor de Ayacucho
Obelisco de la Pampa de la Quinua ©
Obelisco de la Pampa de la Quinua

1
night
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Kick off your visit on the 16th (Sat): contemplate the long history of Sacsayhuaman and then contemplate the long history of Plaza de Armas.

To find maps, other places to visit, ratings, and more tourist information, refer to the Cusco trip planner .

You can fly from Ayacucho to Cusco in 3.5 hours. Alternatively, you can drive; or do a combination of bus and taxi. Plan for little chillier temperatures traveling from Ayacucho in November, with highs in Cusco at 26°C and lows at 8°C. Finish your sightseeing early on the 17th (Sun) so you can travel to Machu Picchu.

Things to do in Cusco

Historic Sites
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Plaza de Armas ©
Plaza de Armas

4
nights
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Visit Santuario Historico de Machu Picchu and Winay Wayna for their historical value. Choquequirao Archeological Park and Sitio arqueológico Pinkuylluna are good opportunities to explore the local culture. Change things up with these side-trips from Machu Picchu: Ollantaytambo (Archaeological Park Ollantaytambo & Lucho Soler). Next up on the itinerary: delve into the distant past at Intipuncu, make a trip to Plaza Manco Capac, take in the architecture and atmosphere at Iglesia Virgen Del Carmen, and take in the natural beauty of Hot Springs (Aguas Calientes).

To see traveler tips, other places to visit, ratings, and more tourist information, read our Machu Picchu trip itinerary planning tool .

Traveling by combination of bus and train from Cusco to Machu Picchu takes 3.5 hours. Alternatively, you can take a train; or drive. Wrap up your sightseeing on the 21st (Thu) early enough to travel to Cusco.

Things to do in Machu Picchu

Historic Sites Parks Nature

Side Trips

Ollantaytambo, Choquequirao Archeological Park
Highlights from your plan
Santuario Historico de Machu Picchu ©
Choquequirao Archeological Park ©
Choquequirao Archeological Park
Winay Wayna ©
Winay Wayna

1
night
Cusco, Peru

Cusco ©
Start off your visit on the 22nd (Fri): delve into the distant past at Q'enqo and then pause for some serene contemplation at Cusco Cathedral.

To see traveler tips, other places to visit, where to stay, and more tourist information, you can read our Cusco trip planning app .

You can do a combination of train and bus from Machu Picchu to Cusco in 3.5 hours. Alternatively, you can take a train; or drive. On the 22nd (Fri), wrap the sightseeing up by early afternoon so you can travel back home.

Things to do in Cusco

Historic Sites
Highlights from your plan
Cusco Cathedral ©
Cusco Cathedral
Q'enqo ©
Q'enqo

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