46 days in Italy Itinerary

46 days in Italy Itinerary

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Route & dates

46 days in Italy Itinerary

Start: Grand Junction
Fly + Drive:  20​h 15​min
1
Positano
— 5 nights
Ferry:  1​h 30​min
2
Salerno
— 6 nights
Train:  1​h 45​min
3
Rome
— 7 nights
Drive:  2​h 15​min
4
Assisi
— 5 nights
Drive:  1​h 45​min
5
Siena
— 5 nights
Bus:  1​h 15​min
6
Florence
— 5 nights
Train:  1​h 45​min
7
Verona
— 5 nights
Bus:  1​h 30​min
8
Venice
— 5 nights
Fly:  22​h 30​min
End: Grand Junction

5
nights
Positano

Positano ©
Often referred to as the gem of the Amalfi Coast, Positano remains one of southern Italy's most sought-after vacation locales, thanks to its hillside location and picturesque, pastel buildings.
Explore the numerous day-trip ideas around Positano: Ravello (Villa Cimbrone Gardens, Cappella Sant'Angelo all'Ospedale, & more) and Amalfi (Wine Tours & Tastings, Cimitero Monumentale, & more). The adventure continues: take some stellar pictures from Il Sentiero Degli Dei, explore the fascinating underground world of Grotte di Suppraiano, get outside with I Suoni degli Dei - Pelagos, and stop by Nana' Positano.

To see more things to do, other places to visit, and more tourist information, go to the Positano trip tool .

Grand Junction, USA to Positano is an approximately 20.5-hour combination of flight and car. Due to the time zone difference, you'll lose 8 hours traveling from Grand Junction to Positano. Traveling from Grand Junction in May, you can expect nighttime temperatures to be somewhat warmer in Positano, with lows of 60°F. Cap off your sightseeing on the 2nd (Tue) early enough to catch the ferry to Salerno.

Things to do in Positano

Outdoors Parks Wildlife

Side Trips

Ravello, Praiano, Amalfi
Highlights from your plan
Fornillo ©
Fornillo
Il Sentiero Degli Dei ©
Il Sentiero Degli Dei
Villa Rufolo ©
Villa Rufolo

6
nights
Salerno

While often overshadowed by the Amalfi Coast's array of quaint villages, Salerno has become one of the region's main areas for culture and entertainment, while remaining relatively unmarked by tourism.
Change things up with these side-trips from Salerno: Paestum Ruins (in Paestum), Chiesa San Pietro Apostolo (in Cetara) and Sorrento (Wine Tours & Tastings & Food Tours). And it doesn't end there: explore the ancient world of Pompeii Archaeological Park, get some thrills on the water with a speed boat tour, get outside with Cilento, and sample the fine beverages at Liquorificio Mansi Carlo.

To find more things to do, other places to visit, reviews, and more tourist information, you can read our Salerno trip itinerary builder tool .

Ride a ferry from Positano to Salerno in 1.5 hours. Alternatively, you can do a combination of taxi and train; or drive. In June, daytime highs in Salerno are 79°F, while nighttime lows are 72°F. Finish up your sightseeing early on the 8th (Mon) so you can catch the train to Rome.

Things to do in Salerno

Tours Historic Sites Outdoors

Side Trips

Sorrento, Tramonti, Vietri sul Mare, Paestum Ruins, Liquorificio Mansi Carlo
Highlights from your plan
Wine Tours & Tastings
Speed Boats Tours
Monte Finestra ©
Monte Finestra

7
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Change things up with these side-trips from Rome: Tivoli (Villa Adriana & Villa d'Este). Next up on the itinerary: delve into the distant past at Colosseum, make a trip to Roman Forum, explore the world behind art at Vatican Museums, and get to know the fascinating history of Piazza Navona.

For traveler tips, photos, more things to do, and tourist information, go to the Rome road trip website .

Traveling by train from Salerno to Rome takes 2 hours. Alternatively, you can drive; or take a bus. Plan for a bit cooler nights when traveling from Salerno in June since evenings lows in Rome dip to 65°F. Cap off your sightseeing on the 15th (Mon) early enough to go by car to Assisi.

Things to do in Rome

Historic Sites Museums Tours

Side Trips

Vatican City, Tivoli
Highlights from your plan
Colosseum ©
Colosseum
Pantheon ©
Pantheon
Trevi Fountain ©
Trevi Fountain

5
nights
Assisi

Assisi ©
Rich in culture and religious tradition, Assisi is known as the birthplace of St.
Change things up with these side-trips from Assisi: Perugia (Museo-Laboratorio di Tessitura a Mano Giuditta Brozzetti & Museo-Laboratorio di Vetrate Artistiche Moretti Caselli), Montioni Frantoio e Cantina (in Montefalco) and Vineria del Carmine (in La Bruna). And it doesn't end there: pause for some serene contemplation at Basilica Papale e Sacro Convento di San Francesco d'Assisi, examine the collection at Museo della Porziuncola, contemplate the long history of San Damiano, and walk around Mount Subasio.

To find ratings, other places to visit, reviews, and tourist information, use the Assisi trip planner .

Traveling by car from Rome to Assisi takes 2.5 hours. Alternatively, you can take a train; or take a bus. Expect slightly colder evenings in Assisi when traveling from Rome in June, with lows around 60°F. Cap off your sightseeing on the 20th (Sat) early enough to go by car to Siena.

Things to do in Assisi

Historic Sites Wineries Museums

Side Trips

Perugia, Azienda Agraria Guerrieri, Montioni Frantoio e Cantina
Highlights from your plan
Tili Vini Societa Agricola ©
Tili Vini Societa Agricola
Azienda Agraria Saio ©
Azienda Agraria Saio

5
nights
Siena

Siena, a medieval Tuscan city, features numerous attractions, including a historic town center, alleyways, towers, and well-preserved buildings.
Explore the numerous day-trip ideas around Siena: Guardastelle Vineyard (in San Gimignano) and Ciacci Piccolomini d'Aragona (in Castelnuovo dell'Abate). Next up on the itinerary: don't miss a visit to Piazza del Campo, deepen your understanding at Scuola di Cucina di Lella, contemplate the long history of Centro Storico di Siena, and relax in the rural setting at Fattoria.

To find ratings, traveler tips, where to stay, and more tourist information, read Siena trip planning website .

Traveling by car from Assisi to Siena takes 2 hours. Alternatively, you can take a bus; or take a train. In June, plan for daily highs up to 84°F, and evening lows to 61°F. Cap off your sightseeing on the 25th (Thu) early enough to catcht the bus to Florence.

Things to do in Siena

Historic Sites Wineries Tours

Side Trips

Ciacci Piccolomini d'Aragona, Guardastelle Vineyard
Highlights from your plan
Wine Tours & Tastings
Piazza del Campo ©
Piazza del Campo
Duomo di Siena ©
Duomo di Siena

5
nights
Florence

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Go for a jaunt from Florence to Pisa to see Leaning Tower of Pisa about 1h 20 min away. There's much more to do: see the interesting displays at Academy Of Florence Art Gallery, take an in-depth tour of Basilica di Santa Croce, take in the spiritual surroundings of Cathedral of Santa Maria del Fiore, and admire the natural beauty at The Boboli Gardens.

To see where to stay, photos, and more tourist information, use the Florence day trip planner .

Traveling by bus from Siena to Florence takes 1.5 hours. Alternatively, you can drive; or take a train. In June in Florence, expect temperatures between 83°F during the day and 65°F at night. Wrap up your sightseeing on the 30th (Tue) early enough to take a train to Verona.

Things to do in Florence

Historic Sites Tours Museums

Side Trip

Leaning Tower of Pisa
Highlights from your plan
Food Tours
Academy Of Florence Art Gallery ©
Academy Of Florence Art Gallery
Piazzale Michelangelo ©
Piazzale Michelangelo

5
nights
Verona

Verona ©
The famous setting for Shakespeare's star-crossed lovers, Romeo and Juliet, Verona is one of northern Italy's main tourist destinations, largely owing to its incredibly rich artistic heritage.
Change things up with these side-trips from Verona: Parma (Caseificio San Pier Damiani & Cattedrale di Parma) and Scuola Italiana di Sci & Snowboard Kristal (in Andalo). Next up on the itinerary: see the grandeur of opera at Arena di Verona, contemplate in the serene atmosphere at Basilica di San Zeno Maggiore, take in panoramic vistas at Torre dei Lamberti, and wander the streets of Quinzano.

To find where to stay, ratings, and tourist information, go to the Verona trip planning app .

Take a train from Florence to Verona in 2 hours. Alternatively, you can drive; or take a bus. In June in Verona, expect temperatures between 84°F during the day and 63°F at night. Wrap up your sightseeing on the 5th (Sun) to allow time to take a bus to Venice.

Things to do in Verona

Historic Sites Outdoors Tours

Side Trips

Parma, Scuola Italiana di Sci & Snowboard Kristal
Highlights from your plan
Arena di Verona ©
Arena di Verona
Piazza delle Erbe ©
Piazza delle Erbe
Museo di Castelvecchio ©
Museo di Castelvecchio

5
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Get out of town with these interesting Venice side-trips: Padua (Basilica di Sant’Antonio & Scrovegni Chapel). There's still lots to do: contemplate the waterfront views at Canal Grande, admire the landmark architecture of Basilica di San Marco, take in panoramic vistas at St Mark's Campanile, and take in the views from Ponte dei Sospiri.

For where to stay, more things to do, other places to visit, and other tourist information, read our Venice trip itinerary planner .

Traveling by bus from Verona to Venice takes 1.5 hours. Alternatively, you can drive; or take a shuttle. Expect a daytime high around 87°F in July, and nighttime lows around 67°F. Wrap up your sightseeing by early afternoon on the 10th (Fri) to allow enough time to travel back home.

Things to do in Venice

Historic Sites Museums Tours

Side Trip

Padua
Highlights from your plan
Canal Grande ©
Canal Grande
Doge's Palace ©
Doge's Palace
Basilica di San Marco
Basilica di San Marco

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