42 days in United States, Argentina & Cuba Itinerary

42 days in United States, Argentina & Cuba Itinerary

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Fly
1
Buenos Aires, Argentina
— 3 nights
Fly
2
Puerto Madryn, Argentina
— 3 nights
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Salta, Argentina
— 3 nights
+2
Drive to Martin Miguel De Guemes International Airport, Fly to El Plumerillo Airport, Drive to Los Sauces
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Los Sauces, Argentina
— 2 nights
Unknown
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Cayo Guillermo, Cuba
— 1 night
Drive
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Trinidad, Cuba
— 3 nights
Bus
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Cayo Largo, Cuba
— 1 night
Fly
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Los Angeles, United States
— 5 nights
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Las Vegas, United States
— 5 nights
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San Francisco, United States
— 5 nights
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Washington DC, United States
— 3 nights
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Buenos Aires, Argentina

— 3 nights

Queen of La Plata

Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Get a sense of the local culture at Puerto Madero and Palermo. Discover out-of-the-way places like Museo de La Plata and Museo Nacional de Bellas Artes. Go for a jaunt from Buenos Aires to Lujan to see Basilica de Lujan about 1h 15 min away. There's still lots to do: explore the world behind art at Museo de Arte Latinoamericano de Buenos Aires, admire the striking features of El Ateneo Grand Splendid, admire the natural beauty at Parque 3 de Febrero, and don't miss a visit to Cemiterio de Recoleta.

To find photos, ratings, reviews, and other tourist information, read Buenos Aires online road trip planner.

Casablanca, Morocco to Buenos Aires is an approximately 16-hour flight. The time zone changes from Western European Standard Time to Argentina Standard Time, which is usually a -3 hour difference. In September, Buenos Aires is little chillier than Casablanca - with highs of 20°C and lows of 13°C. Finish your sightseeing early on the 14th (Fri) so you can fly to Puerto Madryn.

Things to do in Buenos Aires

Neighborhoods · Shopping · Historic Sites · Museums

Side Trips

Puerto Madryn, Argentina

— 3 nights
Whales and penguins frolic in the waters of Puerto Madryn, one of Argentine Patagonia's most important port cities.
Visit Playa La Cantera and Costas de Patagonia for some beach relaxation. Explore hidden gems such as Museo Paleontologico Egidio Feruglio and Museo de Gemas. Venture out of the city with trips to Puerto Piramides (Caleta Valdes & Punta Pardelas). And it doesn't end there: steep yourself in history at The Town of Gaiman, take a leisurely stroll along Muelle Luis Piedra Buena, and pause for some photo ops at Monumento al Indio Tehuelche.

To find where to stay, more things to do, traveler tips, and tourist information, you can read our Puerto Madryn trip itinerary builder app.

You can fly from Buenos Aires to Puerto Madryn in 3.5 hours. Alternatively, you can drive; or take a bus. Wrap up your sightseeing on the 17th (Mon) early enough to fly to Salta.

Things to do in Puerto Madryn

Parks · Beaches · Outdoors · Museums

Side Trips

Salta, Argentina

— 3 nights

Salta the Beautiful

Salta boasts a vibrant social life and array of informative museums appealing to visitors looking for a memorable cultural experience.
Discover out-of-the-way places like MAAM - Museo de Arqueologia de Alta Montana de Salta and Cathedral of Salta. Basilica Menor San Francisco and La Caldera are good opportunities to explore the local culture. Take a break from Salta with a short trip to Horseback Riding Tours in Chicoana, about 46 minutes away. There's much more to do: pause for some serene contemplation at Iglesia Nuestra Senora de La Candelaria de La Vina, contemplate the long history of Convento San Bernardo, take in the spiritual surroundings of Immaculada Madre del Divino Corazon Eucaristico de Jesus, and admire the masterpieces at Museo Pajcha Arte Etnico.

To see photos, more things to do, reviews, and other tourist information, you can read our Salta trip itinerary maker tool.

Fly from Puerto Madryn to Salta in 7 hours. Alternatively, you can drive; or take a bus. In September, daytime highs in Salta are 28°C, while nighttime lows are 9°C. Cap off your sightseeing on the 21st (Fri) early enough to travel to Los Sauces.

Things to do in Salta

Historic Sites · Tours · Outdoors · Neighborhoods

Side Trip

Los Sauces, Argentina

— 2 nights
Kick off your visit on the 21st (Fri): learn about winemaking at Clos de los Siete, learn about winemaking at Bodega Monteviejo, and then learn about winemaking at Gimenez Riili Winery & Vineyards. Here are some ideas for day two: learn about winemaking at Finca Decero, do a tasting at Dolium Winery, and then learn about winemaking at Bodega Benegas.

For traveler tips, maps, photos, and more tourist information, refer to the Los Sauces road trip planner.

Use the Route module to find suitable travel options from Salta to Los Sauces. On the 23rd (Sun), wrap the sightseeing up by early afternoon so you can travel to Cayo Guillermo.

Things to do in Los Sauces

Wineries

Side Trips

Cayo Guillermo, Cuba

— 1 night
A kay of the Jardines del Rey archipelago, Cayo Guillermo has become a popular international tourist destination, buoyed by the construction of luxury all inclusive resorts that dot the paradisal island.
Start off your visit on the 24th (Mon): tour the pleasant surroundings at Cayo Guillermo and then tour the pleasant surroundings at Playa Pilar.

For where to stay, reviews, other places to visit, and tourist information, go to the Cayo Guillermo online visit planner.

Use the Route module to find suitable travel options from Los Sauces to Cayo Guillermo. The time zone difference moving from Argentina Standard Time to Cuba Standard Time is minus 2 hours. In September, plan for daily highs up to 37°C, and evening lows to 28°C. Finish up your sightseeing early on the 25th (Tue) so you can go by car to Trinidad.

Things to do in Cayo Guillermo

Parks · Beaches · Outdoors

Trinidad, Cuba

— 3 nights
Built on sugar and seemingly preserved in molasses, the town of Trinidad attracts visitors with its well-aged 19th century architecture and rustic charm, showcasing the sounds, scents, and sights of days gone by.
Eschew the tourist crowds and head to Ancon Beach and Convento de San Francisco de Asis. Your cultural itinerary includes sights like Plaza Mayor and Colonial Architecture Museum. Step out of Trinidad with an excursion to Delfinario de Cienfuegos in Cienfuegos--about 1h 15 min away. Next up on the itinerary: enjoy the sand and surf at Playa Maria Aguilar, take in the exciting artwork at Galerie D'Art Calleyro, trot along with a tour on horseback, and see the interesting displays at Museo de Historia Municipal.

Plan a trip to Trinidad easily and quickly by telling Inspirock to suggest an itinerary.

You can drive from Cayo Guillermo to Trinidad in 4.5 hours. Alternatively, you can take a bus. In September in Trinidad, expect temperatures between 38°C during the day and 27°C at night. Finish your sightseeing early on the 28th (Fri) so you can take a bus to Cayo Largo.

Things to do in Trinidad

Parks · Outdoors · Wildlife · Beaches

Side Trips

Cayo Largo, Cuba

— 1 night
The stress of modern life feels a million miles away when you holiday on Cayo Largo, a small and unspoiled resort island off the coast of Cuba.
Start off your visit on the 29th (Sat): kick back and relax at Punta Mal Tiempo and then enjoy the sand and surf at Playa Paraiso. On the 30th (Sun), you'll have a packed day of sightseeing: tour the pleasant surroundings at Sea Turtle Hatchery.

To see ratings, traveler tips, other places to visit, and other tourist information, use the Cayo Largo tour website.

Traveling by bus from Trinidad to Cayo Largo takes 4.5 hours. In September, daily temperatures in Cayo Largo can reach 37°C, while at night they dip to 28°C. Wrap up your sightseeing on the 30th (Sun) to allow time to fly to Los Angeles.

Things to do in Cayo Largo

Parks · Beaches · Outdoors · Wildlife

Los Angeles, United States

— 5 nights

City of Angels

Surrounded by mountain ranges, forests, valleys, beaches, and deserts, the metropolitan area of Los Angeles is home to over 17 million people.
Get some cultural insight at The Huntington Library, Art Museum and Botanical Gardens and Santa Monica Pier. Relax by the water at Crystal Cove and Venice Beach and Boardwalk. Explore Los Angeles' surroundings by going to Disneyland Park (in Anaheim) and El Matador State Beach (in Malibu). Next up on the itinerary: examine the collection at The Getty Center, look and learn at Griffith Observatory, admire the striking features of Walt Disney Concert Hall, and get a taste of the local shopping with Abbot Kinney Boulevard.

To see photos, other places to visit, traveler tips, and more tourist information, refer to the Los Angeles trip builder.

Fly from Cayo Largo to Los Angeles in 11.5 hours. Traveling from Cayo Largo to Los Angeles, you'll gain 3 hours due to the time zone difference. In October, Los Angeles is a bit cooler than Cayo Largo - with highs of 32°C and lows of 19°C. Finish your sightseeing early on the 6th (Sat) to allow enough time to fly to Las Vegas.

Things to do in Los Angeles

Parks · Outdoors · Beaches · Theme Parks

Side Trips

Las Vegas, United States

— 5 nights

Sin City

Nicknamed the "Entertainment Capital of the World," Las Vegas sits in the middle of a desert in the southern section of Nevada.
Get some cultural insight at The Strip and The Mob Museum. Discover out-of-the-way places like Valley of Fire State Park and Welcome to Fabulous Las Vegas Sign. Go for a jaunt from Las Vegas to Fort Mohave to see Willow Beach about 1h 10 min away. And it doesn't end there: get engrossed in the history at Titanic, take in breathtaking views at Red Rock Canyon National Conservation Area, examine the collection at The Neon Museum, and have some family-friendly fun at The Roller Coaster.

To see traveler tips and tourist information, refer to the Las Vegas road trip planning app.

Getting from Los Angeles to Las Vegas by flight takes about 3 hours. Other options: drive; or do a combination of train and bus. October in Las Vegas sees daily highs of 32°C and lows of 18°C at night. Finish your sightseeing early on the 11th (Thu) to allow enough time to fly to San Francisco.

Things to do in Las Vegas

Parks · Nature · Museums · Neighborhoods

Side Trips

San Francisco, United States

— 5 nights

City by the Bay

San Francisco is a top holiday destination featuring scenic beauty and great ethnic and cultural diversity.
You'll get in some beach time at Bodega Dunes and China Beach. Eschew the tourist crowds and head to Castello di Amorosa and Twin Peaks. Explore the numerous day-trip ideas around San Francisco: Pescadero (Bean Hollow State Beach, Pebble Beach & Bean Hollow State Beach), Limantour Beach (in Point Reyes National Seashore) and Goat Rock Beach (in Jenner). There's lots more to do: snap pictures at Golden Gate Bridge, take in the waterfront at Fisherman's Wharf, head off the coast to Alcatraz Island, and kick back and relax at Rockaway Beach.

To see photos, maps, ratings, and tourist information, read our San Francisco trip itinerary site.

You can fly from Las Vegas to San Francisco in 3 hours. Other options are to drive; or take a bus. While traveling from Las Vegas, expect slightly colder days and about the same nights in San Francisco, ranging from highs of 26°C to lows of 15°C. Finish up your sightseeing early on the 16th (Tue) so you can catch the flight to Washington DC.

Things to do in San Francisco

Parks · Beaches · Outdoors · Historic Sites

Side Trips

Washington DC, United States

— 3 nights
The capital of the United States, the District of Columbia contains the lion's share of the country's most treasured monuments, memorials, and public museums.
Step off the beaten path and head to National Gallery of Art and Old Town. Satisfy your inner culture vulture at Annapolis Historic District and National Air and Space Museum. Change things up with these side-trips from Washington DC: Skyline Drive (in Shenandoah National Park), U.S. Naval Academy (in Annapolis) and Copper Fox Distillery (in Sperryville).

Plan my Washington DC trip by asking Inspirock to come up with tips and suggestions.

Getting from San Francisco to Washington DC by flight takes about 7 hours. Other options: drive; or do a combination of subway and train. Due to the time zone difference, you'll lose 3 hours traveling from San Francisco to Washington DC. In October, plan for daily highs up to 25°C, and evening lows to 14°C. You'll set off for home on the 20th (Sat).

Things to do in Washington DC

Neighborhoods · Museums · Scenic Drive · Parks

Side Trips

Argentina travel guide

4.4
Landmarks · Bodies of Water · Specialty Museums
Land of Contrasts
Home to the highest and lowest points in South America, diverse Argentina enthralls visitors with its contrasting landscapes and rich cultural heritage. A tour of Argentina reveals a sprawling land of fiercely proud and hardworking gauchos, the legendary cowboys of South America's pampas. A vacation in Argentina also leads you to giant urban centers, filled with modern tourist attractions that include fine restaurants, award-winning museums, and renowned public parks, gardens, and zoos. Away from big cities, Argentina sightseeing combines visits to mighty waterfalls situated inside World Heritage-listed national parks in the north of the country, with excursions to icy glaciers in the south.

Cuba travel guide

4.4
Beaches · Historic Walking Areas · Landmarks
The largest island in the Caribbean, Cuba lies just 140 km (90 mi) south of Florida and captivates a growing number of Western visitors with its tropical landscapes and cultural attractions. Sightseeing in Cuba inevitably begins in Havana, a city of photogenic architecture, lively nightlife, and a passion for baseball. The country's smaller colonial towns usually feature central squares, ideal places to meet the locals under wrought-iron street lamps. Savvy visitors escape the cities during their Cuba holidays, devoting plenty of time to the country's charming countryside, where you can get the feel for this diverse land by conversing with friendly tobacco farmers and small-scale fruit producers.

United States travel guide

4.5
Specialty Museums · Beaches · History Museums
More than the country of car-packed streets seen in TV shows and movies, the United States of America is a complex and diverse home to over 300 million people living in a wide range of landscapes and climates. From its big-city skyscrapers to its sprawling natural parks, the country's ''melting pot'' combines many ethnic groups that share a strong sense of national identity despite their cultural differences. A country of road trips and big blue skies, the United States harbors orderly cities filled with restaurants, parks, museums, and innumerable sightseeing opportunities, as well as pristine natural areas perfect for a holiday in the great outdoors. To see as much as you can of this diverse land quickly, drive over some of the more than 6 million km (4 million mi) of highways leading through deserts, mountain peaks, fertile fields, and giant urban centers.