42 days in South America Itinerary

42 days in South America Itinerary

Created using Inspirock South America trip planner

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Route & dates

42 days in South America Itinerary

Start: Barcelona, Spain
Fly:  22​h 15​min
1
Fernando de Noronha, Brazil
— 5 nights
Fly:  7​h
2
Rio de Janeiro, Brazil
— 5 nights
Fly:  2​h 30​min
3
Foz do Iguacu, Brazil
— 2 nights
Drive:  45​min
4
Iguazu National Park, Argentina
— 2 nights
Fly:  3​h 30​min
5
Buenos Aires, Argentina
— 5 nights
Fly:  6​h 30​min
6
Los Glaciares National Park, Argentina
— 2 nights
+2
Shuttle + Taxi + Fly:  7​h 45​min
7
Santiago, Chile
— 4 nights
+4
Fly + Taxi + Bus + Foot + Train:  19​h 30​min
8
Machu Picchu, Peru
— 1 night
+2
Train + Foot + Bus:  3​h 15​min
9
Cusco, Peru
— 5 nights
+2
Fly + Shuttle + Ferry:  16​h
10
Puerto Ayora, Ecuador
— 5 nights
+3
Bus + Ferry + Shuttle + Fly:  25​h
End: Barcelona, Spain

5
nights
Fernando de Noronha, Brazil

Fernando de Noronha ©
With 21 lush islands scattered among pristine waters in the Atlantic Ocean, a Fernando de Noronha holiday is well worth the effort it takes to get there.
Fernando de Noronha is known for beaches, museums, wildlife, outdoors, and nature. Your plan includes some of its best attractions: kick back and relax at Baia do Sancho, stroll through Praia do Leão, get outside with Morro dois Irmaos, and explore the striking landscape of Fernando de Noronha Marine National Park.

To see more things to do, ratings, reviews, and tourist information, use the Fernando de Noronha tour itinerary builder website .

Barcelona, Spain to Fernando de Noronha is an approximately 22.5-hour flight. The time zone difference when traveling from Barcelona to Fernando de Noronha is minus 3 hours. Plan for warmer temperatures traveling from Barcelona in February, with highs in Fernando de Noronha at 35°C and lows at 29°C. Wrap up your sightseeing on the 22nd (Sat) to allow time to fly to Rio de Janeiro.

Things to do in Fernando de Noronha

Outdoors Parks Beaches
Highlights from your plan
Baia do Sancho ©
Baia do Sancho
Morro dois Irmaos ©
Morro dois Irmaos
Baia dos Porcos ©
Baia dos Porcos

5
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Take a break from Rio de Janeiro with a short trip to Imperial Museum in Petropolis, about 1h 25 min away. There's lots more to do: take your sightseeing to a higher altitude at Pao de Acucar, admire the natural beauty at Jardim Botânico do Rio de Janeiro, enjoy the sand and surf at Barra da Tijuca Beach, and stroll through Pedra do Arpoador.

To see traveler tips, other places to visit, more things to do, and other tourist information, you can read our Rio de Janeiro day trip website .

Traveling by flight from Fernando de Noronha to Rio de Janeiro takes 7 hours. Traveling from Fernando de Noronha to Rio de Janeiro, you'll gain 1 hour due to the time zone difference. In February, plan for daily highs up to 38°C, and evening lows to 28°C. Finish up your sightseeing early on the 27th (Thu) so you can travel to Foz do Iguacu.

Things to do in Rio de Janeiro

Parks Outdoors Beaches

Side Trip

Imperial Museum
Highlights from your plan
Corcovado - Christ the Redeemer ©
Corcovado - Christ the Redeemer
Sugarloaf Mountain ©
Sugarloaf Mountain
Copacabana Beach ©
Copacabana Beach

2
nights
Foz do Iguacu, Brazil

Foz do Iguacu ©
A gateway to the world-renowned Iguacu Falls, which spectacularly divide Brazil and Argentina, the modern, high-rise city of Foz do Iguacu can't help but play second fiddle to the natural wonder in its vicinity.
Start off your visit on the 28th (Fri): see human ingenuity at work at Iguazu Falls, then meet the residents at Parque das Aves Bird Park, and then see the interesting displays at Museu de Cera Dreamland. On the 29th (Sat), you'll have a packed day of sightseeing: take in the spiritual surroundings of Buddhist Temple, then see human ingenuity at work at Itaipu Dam, then contemplate in the serene atmosphere at Mosque of Omar Ibn Al-Khattab, and finally contemplate the long history of Marco Das Tres Fronteiras.

To see maps, ratings, photos, and more tourist information, use the Foz do Iguacu online visit planner .

You can fly from Rio de Janeiro to Foz do Iguacu in 2.5 hours. Other options are to drive; or take a bus. Plan for a bit cooler nights when traveling from Rio de Janeiro in February since evenings lows in Foz do Iguacu dip to 25°C. Finish up your sightseeing early on the 29th (Sat) so you can go by car to Iguazu National Park.

Things to do in Foz do Iguacu

Parks Nature Historic Sites
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Parque das Aves Bird Park ©
Parque das Aves Bird Park
Buddhist Temple ©
Buddhist Temple

2
nights
Iguazu National Park, Argentina

Iguazu National Park ©
Iguazu National Park contains 672 sq km (259 sq mi) of fertile subtropical forests, but its main attraction is the majestic Iguazu Falls.
Kick off your visit on the 1st (Sun): head off the coast to Isla San Martin, admire the sheer force of Salto San Martin, and then admire the sheer force of Iguazu Falls. Keep things going the next day: discover the riches below the earth's surface at Wanda Mines, then explore the activities along Lago Urugua-i, and then take in the dramatic scenery at Salto Bernabe Mendez.

For other places to visit, traveler tips, maps, and tourist information, read our Iguazu National Park tour planning site .

Getting from Foz do Iguacu to Iguazu National Park by car takes about an hour. Other options: take a bus. In February in Iguazu National Park, expect temperatures between 37°C during the day and 24°C at night. Wrap up your sightseeing on the 2nd (Mon) early enough to travel to Buenos Aires.

Things to do in Iguazu National Park

Nature Parks Wildlife

Side Trips

Wanda Mines, Lago Urugua-i
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Salto San Martin ©
Salto San Martin
Isla San Martin ©
Isla San Martin

5
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for nightlife, museums, parks, historic sites, and shopping. Your plan includes some of its best attractions: don't miss a visit to Cemiterio de Recoleta, admire the masterpieces at Museo de Arte Latinoamericano de Buenos Aires, take a stroll through Palermo, and admire the landmark architecture of El Ateneo Grand Splendid.

Plan my day in Buenos Aires using traveler tips and tourist information provided by Inspirock.

Traveling by flight from Iguazu National Park to Buenos Aires takes 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from Iguazu National Park in March, expect nights in Buenos Aires to be about the same, around 20°C, while days are little chillier, around 29°C. Finish your sightseeing early on the 7th (Sat) so you can travel to Los Glaciares National Park.

Things to do in Buenos Aires

Neighborhoods Historic Sites Shopping
Highlights from your plan
Puerto Madero ©
Puerto Madero
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero

2
nights
Los Glaciares National Park, Argentina

Los Glaciares National Park ©
A World Heritage Site, Los Glaciares National Park contains a giant ice cap that feeds 47 vast glaciers.
Kick off your visit on the 8th (Sun): explore the striking landscape at Glaciar Seco. Get ready for a full day of sightseeing on the next day: explore the striking landscape at Glaciar Spegazzini and then explore the striking landscape at Perito Moreno Glacier.

To see reviews, where to stay, maps, and tourist information, read our Los Glaciares National Park online tour itinerary planner .

Fly from Buenos Aires to Los Glaciares National Park in 6.5 hours. Alternatively, you can do a combination of train and bus; or take a bus. When traveling from Buenos Aires in March, plan for much colder days in Los Glaciares National Park, with highs around 15°C, while nights are a bit cooler with lows around 13°C. Wrap up your sightseeing on the 9th (Mon) early enough to travel to Santiago.

Things to do in Los Glaciares National Park

Nature Parks
Highlights from your plan
Perito Moreno Glacier ©
Perito Moreno Glacier
Glaciar Spegazzini ©
Glaciar Spegazzini
Glaciar Seco ©
Glaciar Seco

4
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Venture out of the city with trips to River Rafting & Tubing (in San Jose de Maipo), Concha y Toro (in Pirque) and Valparaiso (La Sebastiana & Walking tours). There's lots more to do: take your sightseeing to a higher altitude at San Cristóbal Hill, make a trip to Plaza de Armas, browse the eclectic array of goods at Central Market (Mercado Central), and admire the landmark architecture of Metropolitan Cathedral (Catedral Metropolitana).

To find more things to do, reviews, photos, and other tourist information, you can read our Santiago trip maker tool .

You can do a combination of shuttle and flight from Los Glaciares National Park to Santiago in 8 hours. Other options are to fly; or take a bus. Traveling from Los Glaciares National Park to Santiago, you'll gain 1 hour due to the time zone difference. Wrap up your sightseeing on the 14th (Sat) to allow time to travel to Machu Picchu.

Things to do in Santiago

Museums Tours Shopping

Side Trips

Valparaiso, Concha y Toro, River Rafting & Tubing
Highlights from your plan
La Chascona ©
La Chascona
San Cristóbal Hill ©
San Cristóbal Hill
Cerro Santa Lucia ©
Cerro Santa Lucia

1
night
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Kick off your visit on the 15th (Sun): take in the architecture and atmosphere at Iglesia Virgen Del Carmen and then delve into the distant past at Santuario Historico de Machu Picchu. Get ready for a full day of sightseeing on the 16th (Mon): look for gifts at Artesanias, take in the natural beauty of Hot Springs (Aguas Calientes), then don't miss a visit to Plaza Manco Capac, then delve into the distant past at Winay Wayna, and finally explore the ancient world of Intipuncu.

For more things to do, where to stay, ratings, and more tourist information, read Machu Picchu itinerary planning app .

Getting from Santiago to Machu Picchu by combination of flight and car takes about 19.5 hours. Other options: drive; or do a combination of bus and train. Traveling from Santiago to Machu Picchu, you'll gain 1 hour due to the time zone difference. Finish your sightseeing early on the 16th (Mon) to allow enough time to travel to Cusco.

Things to do in Machu Picchu

Historic Sites Nature Parks
Highlights from your plan
Santuario Historico de Machu Picchu ©
Winay Wayna ©
Winay Wayna
Intipuncu ©
Intipuncu

5
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Change things up with these side-trips from Cusco: Maras (Moray & Salinas de Maras) and Pisac (in Pisac). And it doesn't end there: steep yourself in history at Sacsayhuaman, admire the masterpieces at Museo de Arte Precolombino, explore the ancient world of Centro Historico De Cusco, and take an in-depth tour of Museo Inka.

To find other places to visit, where to stay, maps, and other tourist information, use the Cusco holiday planner.

Do a combination of train and bus from Machu Picchu to Cusco in 3.5 hours. Alternatively, you can take a train; or drive. In March, plan for daily highs up to 23°C, and evening lows to 9°C. Finish your sightseeing early on the 21st (Sat) to allow enough time to travel to Puerto Ayora.

Things to do in Cusco

Historic Sites Tours Parks

Side Trips

Maras, Pisac, Sacred Valley of the Incas
Highlights from your plan
exploor ©
exploor
Sacsayhuaman ©
Sacsayhuaman
Sacred Valley of the Incas ©
Sacred Valley of the Incas

5
nights
Puerto Ayora, Ecuador

Puerto Ayora ©
The largest settlement in the Galapagos, Puerto Ayora offers visitors to the islands an array of facilities and things to do.
Change things up with a short trip to North Seymour Island in Baltra (about 1h 20 min away). There's much more to do: look for all kinds of wild species at Charles Darwin Research Station, don't miss a visit to Dragon Hill (Cerro Dragon), stroll through Playa de los Alemanes, and take in the exciting artwork at Galeria Aymara.

To see reviews, maps, more things to do, and other tourist information, use the Puerto Ayora trip itinerary maker tool .

You can do a combination of flight and ferry from Cusco to Puerto Ayora in 16 hours. When traveling from Cusco in March, plan for a bit warmer days and much warmer nights in Puerto Ayora: temperatures range from 36°C by day to 28°C at night. Cap off your sightseeing on the 27th (Fri) early enough to travel back home.

Things to do in Puerto Ayora

Parks Outdoors Beaches

Side Trips

Santa Cruz, North Seymour Island
Highlights from your plan
Charles Darwin Research Station ©
Charles Darwin Research Station
Galapagos Beach at Tortuga Bay ©
Galapagos Beach at Tortuga Bay
North Seymour Island ©
North Seymour Island

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