41 days in South America Itinerary

41 days in South America Itinerary

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Route & dates

41 days in South America Itinerary

Start: London, United Kingdom
Fly:  17​h 45​min
1
Cartagena, Colombia
— 4 nights
Fly + Drive:  22​h 30​min
2
Machu Picchu, Peru
— 1 night
+2
train + foot + bus:  3​h 15​min
3
Cusco, Peru
— 5 nights
Fly + bus:  1​h 45​min
4
La Paz, Bolivia
— 4 nights
Drive:  4​h
5
Puno, Peru
— 2 nights
Drive:  4​h 15​min
6
Arequipa, Peru
— 2 nights
Fly:  2​h
7
Lima, Peru
— 6 nights
Fly + Drive:  15​h
8
Riobamba, Ecuador
— 3 nights
Drive:  2​h 45​min
9
Quito, Ecuador
— 5 nights
taxi + Fly:  2​h 30​min
10
Bogota, Colombia
— 6 nights
Fly:  13​h 45​min
End: London, United Kingdom

4
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Cartagena is known for historic sites, museums, nightlife, wildlife, and nature. Your plan includes some of its best attractions: steep yourself in history at Walled City of Cartagena, don't miss a visit to Plaza Bolivar, get the lay of the land with Walking tours, and gain insight at Plaza Santo Domingo.

To see other places to visit, ratings, traveler tips, and more tourist information, read Cartagena trip planning site .

London, UK to Cartagena is an approximately 18-hour combination of flight and bus. You can also fly. The time zone difference moving from Greenwich Mean Time (GMT) to Colombia Time (COT) is minus 5 hours. In September, Cartagena is much warmer than London - with highs of 38°C and lows of 30°C. Finish up your sightseeing early on the 16th (Mon) so you can travel to Machu Picchu.

Things to do in Cartagena

Historic Sites Tours Outdoors
Highlights from your plan
Walled City of Cartagena ©
Walled City of Cartagena
Castillo de San Felipe de Barajas ©
Castillo de San Felipe de Barajas
Plaza Santo Domingo ©
Plaza Santo Domingo

1
night
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
On the 17th (Tue), contemplate the long history of Santuario Historico de Machu Picchu and then delve into the distant past at Intipuncu. Get ready for a full day of sightseeing on the next day: witness a stunning natural landmark at Hot Springs (Aguas Calientes), identify plant and animal life at Los Jardines de Mandor, and then explore the ancient world of Winay Wayna.

For photos, ratings, and tourist information, you can read our Machu Picchu road trip tool .

You can do a combination of flight and car from Cartagena to Machu Picchu in 22.5 hours. Other options are to drive; or do a combination of bus and taxi. Wrap up your sightseeing on the 18th (Wed) to allow time to travel to Cusco.

Things to do in Machu Picchu

Historic Sites Parks Nature
Highlights from your plan
Santuario Historico de Machu Picchu ©
Winay Wayna ©
Winay Wayna
Intipuncu ©
Intipuncu

5
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Change things up with these side-trips from Cusco: Salinas de Maras (in Maras) and Pisac (in Pisac). There's much more to do: delve into the distant past at Sacsayhuaman, pause for some serene contemplation at Iglesia De Santo Domingo, contemplate the long history of Plaza de Armas, and admire the landmark architecture of Centro Historico De Cusco.

To see reviews, other places to visit, and other tourist information, read Cusco road trip planning website .

Traveling by combination of train and bus from Machu Picchu to Cusco takes 3.5 hours. Alternatively, you can take a train; or drive. In September in Cusco, expect temperatures between 25°C during the day and 5°C at night. Cap off your sightseeing on the 23rd (Mon) early enough to travel to La Paz.

Things to do in Cusco

Historic Sites Museums Parks

Side Trips

Pisac, Salinas de Maras, Sacred Valley of the Incas
Highlights from your plan
exploor ©
exploor
Sacsayhuaman ©
Sacsayhuaman
Plaza de Armas ©
Plaza de Armas

4
nights
La Paz, Bolivia

La Paz ©
Take a moment to catch your breath as you commence your holiday in La Paz.
Spend the 24th (Tue) exploring the striking scenery along WMDR Yungas Road. There's still lots to do: explore the ancient world of Tiwanaku, examine the collection at Museo de Textiles Andinos Bolivianos, enjoy some diversion at Urban Rush Bolivia, and take your sightseeing to a higher altitude at Huayna Potosi.

For ratings, where to stay, and more tourist information, read La Paz trip maker .

Do a combination of flight and bus from Cusco to La Paz in 2 hours. Alternatively, you can drive; or take a bus. The time zone changes from Peru Time to Bolivia Time, which is usually a 1 hour difference. Expect a bit cooler temperatures when traveling from Cusco in September; daily highs in La Paz reach 18°C and lows reach 0°C. Wrap up your sightseeing on the 27th (Fri) early enough to drive to Puno.

Things to do in La Paz

Outdoors Parks Scenic Drive
Highlights from your plan
Urban Rush Bolivia ©
Urban Rush Bolivia
Tiwanaku ©
Tiwanaku
WMDR Yungas Road ©
WMDR Yungas Road

2
nights
Puno, Peru

Puno ©
Hugging the western tip of Lake Titicaca, Puno serves as a melting pot of indigenous and imported cultures, and makes a great base for explorations around the region.
Start off your visit on the 28th (Sat): step off the mainland to explore Uros Floating Islands and then step off the mainland to explore Taquile Island. On the 29th (Sun), you'll have a packed day of sightseeing: explore the different monuments and memorials at Sillustani, then explore the activities along Lake Titicaca, and then don't miss a visit to Chullpas.

To find more things to do, traveler tips, other places to visit, and other tourist information, go to the Puno route planner.

Drive from La Paz to Puno in 4 hours. Alternatively, you can take a bus. Due to the time zone difference, you'll gain 1 hour traveling from La Paz to Puno. Traveling from La Paz in September, you will find days in Puno are somewhat warmer (22°C), and nights are about the same (0°C). Finish your sightseeing early on the 29th (Sun) so you can drive to Arequipa.

Things to do in Puno

Parks Nature Historic Sites

Side Trip

Chullpas
Highlights from your plan
Taquile Island ©
Taquile Island
Uros Floating Islands ©
Uros Floating Islands
Lake Titicaca ©
Lake Titicaca

2
nights
Arequipa, Peru

Arequipa ©
In an area dominated three imposing volcanoes, Arequipa vacations allow visitors to admire well-preserved colonial architecture in a dramatic setting.
Start off your visit on the 30th (Mon): admire the striking features of La Mansion del Fundador, don't miss a visit to Plaza de Armas, take an in-depth tour of Museo Santuarios Andinos, then examine the collection at Santa Catalina Monastery, and finally contemplate the long history of Historic Centre of Arequipa. Get ready for a full day of sightseeing on the next day: examine the collection at MUVI Museo Vivencial del Vino y Pisco and then get impressive views of Volcan Misti.

To see reviews, more things to do, maps, and more tourist information, use the Arequipa tour planner.

You can drive from Puno to Arequipa in 4.5 hours. Alternatively, you can take a bus. Plan for somewhat warmer nights when traveling from Puno in September since evenings lows in Arequipa dip to 11°C. Wrap up your sightseeing on the 1st (Tue) to allow time to travel to Lima.

Things to do in Arequipa

Parks Nature Museums
Highlights from your plan
Volcan Misti ©
Volcan Misti
Santa Catalina Monastery ©
Santa Catalina Monastery
Plaza de Armas ©
Plaza de Armas

6
nights
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Lima is known for parks, historic sites, museums, shopping, and nightlife. Your plan includes some of its best attractions: get engrossed in the history at Museo Larco, shop like a local with Shopping Center Larcomar (Centro Comercial Larcomar), pause for some serene contemplation at Iglesia y Convento de San Francisco, and ponder the design of Plaza de Armas (Plaza Mayor).

For traveler tips, reviews, ratings, and tourist information, read Lima attractions planning site .

Traveling by flight from Arequipa to Lima takes 2 hours. Alternatively, you can drive; or take a bus. Expect a bit warmer evenings in Lima when traveling from Arequipa in October, with lows around 19°C. Finish your sightseeing early on the 7th (Mon) to allow enough time to travel to Riobamba.

Things to do in Lima

Museums Historic Sites Neighborhoods
Highlights from your plan
Museo Larco ©
Museo Larco
Plaza de Armas (Plaza Mayor) ©
Plaza de Armas (Plaza Mayor)
Huaca Pucllana ©
Huaca Pucllana

3
nights
Riobamba, Ecuador

Riobamba ©
Riobamba is the capital of the Chimborazo Province in central Ecuador, which is located at the Chambo River Valley of the Andes. Explore the numerous day-trip ideas around Riobamba: Banos (Church of the Virgin of the Holy Water (Nuestra Senora del Agua Santa), Canopy double puerta del cielo, & more). Spend the 10th (Thu) exploring nature at Sangay National Park. Next up on the itinerary: explore the landscape on two wheels at Pro Bici and admire the masterpieces at Museo de Arte Religioso de la Concepcion.

To see traveler tips, more things to do, reviews, and tourist information, go to the Riobamba visit planner .

Explore your travel options from Lima to Riobamba with the Route module. Traveling from Lima in October, you can expect nighttime temperatures to be slightly colder in Riobamba, with lows of 13°C. Finish up your sightseeing early on the 11th (Fri) so you can go by car to Quito.

Things to do in Riobamba

Parks Nature Outdoors

Side Trip

Banos
Highlights from your plan
Pro Bici ©
Pro Bici
Sangay National Park ©
Sangay National Park
Tungurahua
Tungurahua

5
nights
Quito, Ecuador

Quito ©
High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
You'll find plenty of places to visit near Quito: Cuicocha (in Cotacachi) and Termas de Papallacta (in Papallacta). Spend the 15th (Tue) among the fascinating landscape of Cotopaxi National Park. The adventure continues: admire the landmark architecture of Fundacion Iglesia de la Compania, contemplate in the serene atmosphere at San Francisco Church (Iglesia de San Francisco), get to know the fascinating history of Quito Old Town, and don't miss a visit to Mitad Del Mundo.

Ask Inspirock to suggest an itinerary and make planning a trip to Quito fast, fun, and easy.

Traveling by car from Riobamba to Quito takes 3 hours. Alternatively, you can take a bus. Traveling from Riobamba in October, plan for somewhat warmer nights in Quito, with lows around 17°C. Finish your sightseeing early on the 16th (Wed) so you can travel to Bogota.

Things to do in Quito

Parks Nature Wildlife

Side Trips

Cotopaxi National Park, Cuicocha, Termas de Papallacta
Highlights from your plan
Cuicocha ©
Cuicocha
Fundacion Iglesia de la Compania ©
Fundacion Iglesia de la Compania

6
nights
Bogota, Colombia

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Explore the numerous day-trip ideas around Bogota: Catedral de Sal de Zipaquira (in Zipaquira), Vivero Crisalide (in Chia) and Laguna de Guatavita (in Tierra Negra). There's still lots to do: examine the collection at Gold Museum (Museo del Oro), contemplate the long history of Bolivar plaza, browse the collection at Biblioteca Virgilio, and don't miss a visit to Casa Libreria Wilborada 1047.

For ratings, maps, where to stay, and tourist information, read our Bogota online day trip planner .

Do a combination of taxi and flight from Quito to Bogota in 2.5 hours. Alternatively, you can drive; or take a bus. In October, Bogota is little chillier than Quito - with highs of 22°C and lows of 9°C. Wrap up your sightseeing on the 22nd (Tue) to allow time to travel back home.

Things to do in Bogota

Parks Nature Museums

Side Trips

Laguna de Guatavita, Vivero Crisalide, Catedral de Sal de Zipaquira
Highlights from your plan
Food Tours
Gold Museum (Museo del Oro) ©
Gold Museum (Museo del Oro)

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