32 days in South America, Central America & Europe Itinerary

32 days in South America, Central America & Europe Itinerary

Created using Inspirock route planner

Make it your trip
Fly
1
Punta del Este, Uruguay
— 1 night
Drive
2
Montevideo, Uruguay
— 2 nights
Drive
3
Colonia del Sacramento, Uruguay
— 1 night
Ferry
4
Buenos Aires, Argentina
— 3 nights
Fly
5
San Carlos de Bariloche, Argentina
— 2 nights
Fly
6
Mendoza, Argentina
— 3 nights
Fly
7
Santiago, Chile
— 4 nights
Fly
8
Medellin, Colombia
— 3 nights
Fly
9
Panama City, Panama
— 4 nights
Fly
10
Barcelona, Spain
— 8 nights
Fly

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Punta del Este, Uruguay

— 1 night

Monaco of South America

With plenty of modern casinos, well-developed beaches, chic restaurants, and upscale hotels, Punta del Este vacations draw visitors from Argentina, Brazil, and beyond.
Kick off your visit on the 5th (Wed): tour the pleasant surroundings at Playa Brava, make a trip to Puerto de Punta del Este, and then don't miss a visit to The Fingers of Punta del Este. On the 6th (Thu), you'll have a packed day of sightseeing: try your luck at Conrad Casino, kick back and relax at Playa Mansa, examine the collection at Museo Del Mar, then don't miss a visit to Fundacion Pablo Atchugarry, and finally make a trip to La Vista Punta Del Este.

Inspirock's itinerary builder makes planning a Punta del Este trip simple and quick.

Sao Paulo, Brazil to Punta del Este is an approximately 5.5-hour flight. You can also drive; or take a bus. Expect slightly colder temperatures when traveling from Sao Paulo in May; daily highs in Punta del Este reach 20°C and lows reach 15°C. Finish your sightseeing early on the 6th (Thu) to allow enough time to drive to Montevideo.

Things to do in Punta del Este

Parks · Beaches · Outdoors · Fun & Games

Side Trip

Montevideo, Uruguay

— 2 nights
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
On the 7th (Fri), take a stroll through Ciudad Vieja, take in the spiritual surroundings of Catedral de Montevideo, see the interesting displays at 1972 Museum, ponder the world of politics at Palacio Legislativo, then admire the masterpieces at Museo Municipal de Bellas Artes Juan Manuel Blanes, and finally do a tasting at Bouza Bodega Boutique. On the 8th (Sat), you'll have a packed day of sightseeing: take some stellar pictures from Mirador Panoramico de Montevideo, make a trip to Plaza Independencia, then explore the world behind art at Palacio Taranco, then take in the pleasant sights at Rambla de Montevideo, and finally take a stroll through Pocitos.

To find where to stay, reviews, more things to do, and more tourist information, refer to the Montevideo driving holiday planner.

Getting from Punta del Este to Montevideo by car takes about 2 hours. Other options: take a bus. Traveling from Punta del Este in May, Montevideo is little chillier at night with lows of 11°C. Finish your sightseeing early on the 8th (Sat) to allow enough time to drive to Colonia del Sacramento.

Things to do in Montevideo

Museums · Neighborhoods · Wineries · Historic Sites

Colonia del Sacramento, Uruguay

— 1 night
Sleepy cobbled streets lined with pastel-colored houses lead down to the water in Colonia del Sacramento.
Kick off your visit on the 9th (Sun): pause for some serene contemplation at Basilica De Santisimo Sacramento, take a stroll through Barrio Historico, enjoy the sea views from Colonia del Sacramento Lighthouse, then make a trip to La Calle de los Suspiros, then get engrossed in the history at Museo Portugues, and finally take in the pleasant sights at Rambla Colonia Del Sacramento.

To find maps and tourist information, refer to the Colonia del Sacramento online itinerary planner.

Getting from Montevideo to Colonia del Sacramento by car takes about 3 hours. Other options: take a bus. In May, daytime highs in Colonia del Sacramento are 20°C, while nighttime lows are 13°C. Cap off your sightseeing on the 9th (Sun) early enough to catch the ferry to Buenos Aires.

Things to do in Colonia del Sacramento

Historic Sites · Museums · Neighborhoods

Buenos Aires, Argentina

— 3 nights

Queen of La Plata

Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Do some cultural sightseeing at Palermo Soho and Museo Nacional de Bellas Artes. Eschew the tourist crowds and head to Museo de Arte Latinoamericano de Buenos Aires and Parque 3 de Febrero. There's still lots to do: take a stroll through Puerto Madero, explore the engaging exhibits at Museo de los Ninos, stroll the grounds of Cemiterio de Recoleta, and admire the striking features of Palacio Barolo.

To find traveler tips, more things to do, where to stay, and other tourist information, refer to the Buenos Aires road trip app.

Getting from Colonia del Sacramento to Buenos Aires by ferry takes about 2 hours. In May, daily temperatures in Buenos Aires can reach 20°C, while at night they dip to 14°C. Finish up your sightseeing early on the 12th (Wed) so you can catch the flight to San Carlos de Bariloche.

Things to do in Buenos Aires

Neighborhoods · Historic Sites · Museums · Shopping

San Carlos de Bariloche, Argentina

— 2 nights
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
On the 13th (Thu), stop by Chocolates Rapanui, take in the architecture and atmosphere at Iglesia Nuestra Senora del Nahuel Huapi, then get a dose of the wild on a nature and wildlife tour, then take in the dramatic scenery at Cascada de los Duendes, and finally see the interesting displays at Museo del Lago Gutierrez. Here are some ideas for day two: take a tour by water with Boat Tours & Water Sports, then walk around Parque Nahuelito, then stroll through Isla Victoria, and finally take a peaceful walk through Sendero de los Arrayanes.

To see where to stay, maps, more things to do, and tourist information, read our San Carlos de Bariloche road trip app.

Fly from Buenos Aires to San Carlos de Bariloche in 4 hours. Alternatively, you can drive; or take a bus. Plan for little chillier temperatures traveling from Buenos Aires in May, with highs in San Carlos de Bariloche at 12°C and lows at 1°C. Finish up your sightseeing early on the 14th (Fri) so you can catch the flight to Mendoza.

Things to do in San Carlos de Bariloche

Parks · Outdoors · Nature · Tours

Mendoza, Argentina

— 3 nights
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Get some cultural insight at Wine Tours & Tastings and Pulenta Estate Winery. Step off the beaten path and head to Casa El Enemigo and Bodega Chandon. When in Mendoza, make a side trip to see Bodegas Salentein in Los Arboles, approximately Los Arboles away. Next up on the itinerary: do a tasting at Bodega Roberto Bonfanti.

For reviews, photos, traveler tips, and tourist information, use the Mendoza road trip planner.

Traveling by flight from San Carlos de Bariloche to Mendoza takes 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from San Carlos de Bariloche in May, expect Mendoza to be somewhat warmer, temps between 21°C and 9°C. Finish your sightseeing early on the 17th (Mon) so you can fly to Santiago.

Things to do in Mendoza

Wineries · Tours

Side Trips

Santiago, Chile

— 4 nights

City of the Island Hills

Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Discover out-of-the-way places like Vina Santa Rita and Museo Chileno de Arte Precolombino. Do some cultural sightseeing at Casa de Isla Negra and La Sebastiana. Go for a jaunt from Santiago to Lo Abarca to see Casa Marin Winery about 1h 20 min away. There's much more to do: take an in-depth tour of Museo de la Memoria y los Derechos Humanos, browse the eclectic array of goods at Central Market (Mercado Central), walk around Cerro Santa Lucia, and take your sightseeing to a higher altitude at San Cristóbal Hill.

To see reviews, traveler tips, ratings, and other tourist information, use the Santiago trip planner.

Traveling by flight from Mendoza to Santiago takes 4.5 hours. Alternatively, you can drive; or take a bus. Traveling from Mendoza to Santiago, you'll gain 1 hour due to the time zone difference. Wrap up your sightseeing by early afternoon on the 21st (Fri) to allow enough time to fly to Medellin.

Things to do in Santiago

Museums · Parks · Wineries · Nature

Side Trips

Medellin, Colombia

— 3 nights

City of the Eternal Spring

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Discover out-of-the-way places like Museo de Antioquia and Parque Explora. El Castillo Museo y Jardines and Iglesia De La Veracruz are good opportunities to explore the local culture. There's lots more to do: get the lay of the land with Walking tours, pause for some serene contemplation at Templo Parroquial Jesus Nazareno, explore the activities along Laguna de Guatape, and tour the pleasant surroundings at Parque Arvi.

To see more things to do, reviews, where to stay, and other tourist information, refer to the Medellin trip itinerary planning site.

Traveling by flight from Santiago to Medellin takes 11.5 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Santiago to Medellin is minus 1 hour. In May in Medellin, expect temperatures between 32°C during the day and 20°C at night. Cap off your sightseeing on the 24th (Mon) early enough to catch the flight to Panama City.

Things to do in Medellin

Parks · Tours · Museums · Nature

Panama City, Panama

— 4 nights

Dubai of Latin America

Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Museum-lovers will appreciate Biomuseo and Museo del Canal Interoceanico de Panama. Explore hidden gems such as Cinta Costera and Panama La Vieja. There's lots more to do: make a trip to Avenida Balboa, explore the ancient world of Iglesia de la Compania de Jesus, take a stroll through Via Espana, and take in the architecture and atmosphere at El Arco Chato.

To see photos, other places to visit, traveler tips, and other tourist information, read Panama City trip itinerary builder site.

Fly from Medellin to Panama City in 4.5 hours. Alternatively, you can do a combination of bus, ferry, and taxi; or do a combination of bus and ferry. Prepare for somewhat warmer weather when traveling from Medellin in May: high temperatures in Panama City hover around 36°C and lows are around 29°C. Finish up your sightseeing early on the 28th (Fri) so you can catch the flight to Barcelona.

Things to do in Panama City

Historic Sites · Neighborhoods · Museums · Shopping

Barcelona, Spain

— 8 nights

Jewel of the Mediterranean

Barcelona, the country’s second-largest city, is a cosmopolitan urban center known for its throbbing youthful energy and stellar architecture.
Get a sense of the local culture at Basilica of the Sagrada Familia and El Barri Gòtic. Discover out-of-the-way places like Carrer del Mirador del Palau Nacional and Dali-Gala Castle Museum-House (Castell de Pubol). Explore Barcelona's surroundings by going to Vila Vella (Old Town) (in Tossa de Mar), Iglesia Ortodoxa Lloret de Mar (in Lloret de Mar) and Girona (Girona Cathedral (Catedral), Patronat Call de Girona, &more). The adventure continues: wander the streets of Las Ramblas, get engrossed in the history at Museu d'Història de Barcelona MUHBA, browse the exhibits of Casa Vicens, and see the interesting displays at Hash Marihuana & Hemp Museum.

To see maps, where to stay, photos, and more tourist information, read Barcelona trip tool.

Traveling by flight from Panama City to Barcelona takes 16 hours. Due to the time zone difference, you'll lose 6 hours traveling from Panama City to Barcelona. Traveling from Panama City in May, expect nights in Barcelona to be cooler, around 16°C, while days are little chillier, around 25°C. Wrap up your sightseeing by early afternoon on the 5th (Sat) to allow time for the flight back home.

Things to do in Barcelona

Historic Sites · Neighborhoods · Museums · Parks

Side Trips

Uruguay travel guide

4
Landmarks · Scenic Walking Areas · Art Museums
Switzerland of South America
One of the smallest countries in South America, tourist-friendly Uruguay is often called the "Switzerland of South America" because of its consistent economic development and progressive society. Open-minded Montevideo serves as the starting point of most Uruguay vacations, offering visitors an eclectic cultural scene and a chance to discover some of South America's major architectural treasures. Away from the cosmopolitan capital city, vacations in Uruguay involve exploring wildlife-rich areas along the Atlantic and touring the rustic interior on horseback, gaucho style. In this sports-loving country, the highlight of your Uruguay trip might just be a soccer match between Penarol and Nacional, the country's two major clubs.

Argentina travel guide

4.4
Landmarks · Bodies of Water · Specialty Museums
Land of Contrasts
Home to the highest and lowest points in South America, diverse Argentina enthralls visitors with its contrasting landscapes and rich cultural heritage. A tour of Argentina reveals a sprawling land of fiercely proud and hardworking gauchos, the legendary cowboys of South America's pampas. A vacation in Argentina also leads you to giant urban centers, filled with modern tourist attractions that include fine restaurants, award-winning museums, and renowned public parks, gardens, and zoos. Away from big cities, Argentina sightseeing combines visits to mighty waterfalls situated inside World Heritage-listed national parks in the north of the country, with excursions to icy glaciers in the south.

Chile travel guide

4.3
Landmarks · Parks · Specialty Museums
Land of Poets
Squeezed between the Andes and the Pacific Ocean, geographically diverse Chile is a long, thin stretch of land encompassing some of the world's driest deserts in the north, and some of its largest glacial fields in the south. Though most Chile holidays include some form of adventure in the vast wilderness areas, the country also contains charming cities providing plenty of urban things to do and see. Many tours of Chile include at least a brief visit to the country's lush wine regions, where backyard vineyards compete with sprawling estates producing some of the world's most respected whites and reds.