30 days in South America, Central America & Mexico Itinerary

30 days in South America, Central America & Mexico Itinerary

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Route & dates

30 days in South America, Central America & Mexico Itinerary

Start: Melbourne, Australia
Fly:  17​h 45​min
1
Santiago, Chile
— 1 night
Fly:  6​h 15​min
2
Cusco, Peru
— 3 nights
Fly:  7​h 15​min
3
Medellin, Colombia
— 3 nights
Fly:  4​h
4
Cartagena, Colombia
— 4 nights
Fly:  5​h
5
Panama City, Panama
— 3 nights
Drive:  29​h
6
Antigua, Guatemala
— 3 nights
shuttle + Fly:  7​h 30​min
7
Cozumel, Mexico
— 4 nights
Drive:  2​h 30​min
8
Tulum, Mexico
— 4 nights
+2
bus + foot + Fly:  26​h
End: Melbourne, Australia

1
night
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Kick off your visit on the 11th (Sat): steep yourself in history at Centro Cultural Palacio de la Moneda y Plaza de la Ciudadania, then take some stellar pictures from San Cristóbal Hill, and then don't miss a visit to Santa Lucia Hill.

To find more things to do, photos, maps, and other tourist information, go to the Santiago trip itinerary builder .

Melbourne, Australia to Santiago is an approximately 18-hour flight. You can also do a combination of shuttle and flight; or do a combination of train and flight. The time zone difference moving from Australian Eastern Standard Time (Victoria) (AEST) to Chile Time (CLT) is minus 14 hours. Finish up your sightseeing early on the 11th (Sat) so you can travel to Cusco.

Things to do in Santiago

Nature Parks Museums
Highlights from your plan
San Cristóbal Hill ©
San Cristóbal Hill
Santa Lucia Hill ©
Santa Lucia Hill

3
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Step out of Cusco to go to Urubamba and see Cerveceria Willkamayu, which is approximately 48 minutes away. There's still lots to do: delve into the distant past at Sacsayhuaman, pause for some serene contemplation at Iglesia De Santo Domingo, steep yourself in history at Plaza de Armas, and admire the landmark architecture of Centro Historico De Cusco.

To see ratings, maps, more things to do, and more tourist information, use the Cusco visit planner .

Getting from Santiago to Cusco by flight takes about 6.5 hours. Other options: drive; or take a bus. Traveling from Santiago to Cusco, you'll gain 1 hour due to the time zone difference. In April in Cusco, expect temperatures between 23°C during the day and 7°C at night. Wrap up your sightseeing on the 14th (Tue) to allow time to travel to Medellin.

Things to do in Cusco

Historic Sites Museums Tours

Side Trips

Sacred Valley of the Incas, Cerveceria Willkamayu
Highlights from your plan
exploor ©
exploor
Sacsayhuaman ©
Sacsayhuaman
Sacred Valley of the Incas ©
Sacred Valley of the Incas

3
nights
Medellin, Colombia

Medellin ©
Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Change things up with a short trip to Piedra Del Penol in Guatape (about 1h 50 min away). There's still lots to do: stroll through 2000m Descent and more, take in the architecture and atmosphere at Templo Parroquial Jesus Nazareno, get the lay of the land with Walking tours, and stop by Duna Store.

To see other places to visit, where to stay, photos, and more tourist information, you can read our Medellin online travel route planner .

Traveling by flight from Cusco to Medellin takes 7.5 hours. Alternatively, you can drive; or take a bus. When traveling from Cusco in April, plan for a bit warmer days and much hotter nights in Medellin: temperatures range from 32°C by day to 20°C at night. Finish your sightseeing early on the 18th (Sat) so you can travel to Cartagena.

Things to do in Medellin

Parks Wildlife Outdoors

Side Trip

Piedra Del Penol
Highlights from your plan
Parque Explora ©
Parque Explora
Walking tours
Parque Arvi ©
Parque Arvi

4
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
When in Cartagena, make a side trip to see Playa Blanca in Isla Baru, approximately 1h 05 min away. There's lots more to do: steep yourself in history at Walled City of Cartagena, get the lay of the land with Walking tours, make a trip to Castillo de San Felipe de Barajas, and take in the spiritual surroundings of Convent of Santa Cruz de la Popa.

To see maps, photos, traveler tips, and tourist information, go to the Cartagena driving holiday planning tool .

You can fly from Medellin to Cartagena in 4 hours. Other options are to do a combination of flight and bus; or drive. Prepare for somewhat warmer weather when traveling from Medellin in April: high temperatures in Cartagena hover around 38°C and lows are around 30°C. Finish your sightseeing early on the 22nd (Wed) so you can travel to Panama City.

Things to do in Cartagena

Historic Sites Outdoors Tours

Side Trip

Playa Blanca
Highlights from your plan
Castillo de San Felipe de Barajas ©
Castillo de San Felipe de Barajas
Walled City of Cartagena ©
Walled City of Cartagena
Plaza Santo Domingo ©
Plaza Santo Domingo

3
nights
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Panama City is known for historic sites, shopping, museums, nature, and nightlife. Your plan includes some of its best attractions: make a trip to Panama Canal, explore the ancient world of Panama La Vieja, explore the wealth of natural beauty at Metropolitan National Park, and wander the streets of Casco Viejo.

For maps, where to stay, ratings, and other tourist information, you can read our Panama City trip builder .

Traveling by flight from Cartagena to Panama City takes 5 hours. Alternatively, you can do a combination of bus and flight; or do a combination of flight and taxi. In April, daily temperatures in Panama City can reach 38°C, while at night they dip to 30°C. Finish your sightseeing early on the 25th (Sat) so you can drive to Antigua.

Things to do in Panama City

Historic Sites Neighborhoods Museums
Highlights from your plan
Casco Viejo ©
Casco Viejo
Panama Canal ©
Panama Canal
Amador Causeway (Calzada de Amador) ©

3
nights
Antigua, Guatemala

Antigua ©
The former capital of Guatemala and a World Heritage Site, Antigua retains its colonial charm and remains one of the most visited destinations in the country.
You'll find plenty of places to visit near Antigua: Guatemala City (Catedral Metropolitana & La Aurora Zoo). There's lots more to do: contemplate the geological forces at Volcán Pacaya, look for gifts at Joyeria C'Santos Antigua, make a trip to The Plaza Central Park, and delve into the distant past at Arco de Santa Catalina.

To find more things to do, where to stay, reviews, and other tourist information, use the Antigua travel route planner.

You can drive from Panama City to Antigua in 29 hours. Alternatively, you can take a bus; or take a bus. Due to the time zone difference, you'll gain 1 hour traveling from Panama City to Antigua. Traveling from Panama City in April, expect nights in Antigua to be much colder, around 17°C, while days are a bit cooler, around 32°C. Wrap up your sightseeing on the 29th (Wed) early enough to travel to Cozumel.

Things to do in Antigua

Parks Nature Historic Sites

Side Trip

Guatemala City
Highlights from your plan
Volcán Pacaya ©
Volcán Pacaya
Iglesia de La Merced ©
Iglesia de La Merced
Cerro de la Cruz ©
Cerro de la Cruz

4
nights
Cozumel, Mexico

Thanks to the island's outstanding scuba diving and snorkeling options, Cozumel tourism sector remains a major employer and the main source of income for this Caribbean getaway.
Cozumel is known for wildlife, outdoors, theme parks, adventure, and beaches. Your plan includes some of its best attractions: see some colorful creatures with a scuba or snorkeling tour, take in the dramatic natural features at Palancar Reef, try out the rides at Discover Mexico Park Cozumel, and get outside with Mr Sanchos Beach Club Cozumel.

For other places to visit, reviews, ratings, and other tourist information, use the Cozumel visit site .

Do a combination of shuttle and flight from Antigua to Cozumel in 7.5 hours. Alternatively, you can do a combination of bus and ferry. Traveling from Antigua to Cozumel, you'll lose 1 hour due to the time zone difference. Traveling from Antigua in April, Cozumel is a bit warmer at night with lows of 24°C. Cap off your sightseeing on the 3rd (Sun) early enough to go by car to Tulum.

Things to do in Cozumel

Outdoors Theme Parks Wildlife
Highlights from your plan
Scuba & Snorkeling
Discover Mexico Park Cozumel ©
Discover Mexico Park Cozumel
Palancar Reef ©
Palancar Reef

4
nights
Tulum, Mexico

Tulum ©
The only Mayan site built to overlook the ocean, Tulum remains a coastal paradise preserving the last vestiges of a pre-Hispanic civilization.
Venture out of the city with trips to Chichen Itza (in Chichen Itza), Cobá Zona Arqueológica Cobá (in Coba) and Playa del Carmen (Xcaret Park & Scuba & Snorkeling). There's lots more to do: explore the ancient world of Tulum Archaeological Site, stop by Kaahal Home Tulum, explore the activities along Casa Cenote, and get engrossed in the history at Museo de la Prehistoria Parque Dos Ojos.

To find traveler tips, photos, reviews, and other tourist information, you can read our Tulum trip itinerary builder website .

Drive from Cozumel to Tulum in 2.5 hours. May in Tulum sees daily highs of 34°C and lows of 25°C at night. Finish your sightseeing early on the 7th (Thu) to allow enough time to travel back home.

Things to do in Tulum

Theme Parks Historic Sites Tours

Side Trips

Playa del Carmen, Chichen Itza, Cobá Zona Arqueológica Cobá
Highlights from your plan
Tulum Archaeological Site ©
Tulum Archaeological Site
Xcaret Park ©
Xcaret Park
Scuba & Snorkeling

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