28 days in South America Itinerary

28 days in South America Itinerary

Created using Inspirock South America trip planner

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Make it your trip
Fly
1
Montevideo, Uruguay
— 3 nights
Drive
2
Colonia del Sacramento, Uruguay
— 1 night
Ferry
3
Buenos Aires, Argentina
— 4 nights
Fly
4
Santiago, Chile
— 4 nights
Drive
5
Valparaiso, Chile
— 1 night
Fly
6
San Pedro de Atacama, Chile
— 4 nights
Drive
7
Uyuni, Bolivia
— 1 night
Fly
8
La Paz, Bolivia
— 2 nights
Fly
9
Cusco, Peru
— 3 nights
Bus to Ollantaytambo, Train to Machu Picchu
10
Machu Picchu, Peru
— 1 night
Train to Ollantaytambo, Bus to Cusco
11
Cusco, Peru
— 1 night
Fly

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Montevideo, Uruguay

— 3 nights
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
Change things up with a short trip to Pizzorno Family Estates in Canelones (about 44 minutes away). There's much more to do: make a trip to Plaza Independencia, take in panoramic vistas at Mananas en el Salvo, contemplate in the serene atmosphere at Catedral de Montevideo, and admire the landmark architecture of Palacio Salvo.

To find more things to do, maps, and other tourist information, go to the Montevideo trip planning website.

Lisbon, Portugal to Montevideo is an approximately 17.5-hour flight. The time zone changes from Western European Standard Time to Uruguay Standard Time, which is usually a -3 hour difference. Traveling from Lisbon in July, you will find days in Montevideo are much colder (18°C), and nights are slightly colder (7°C). Finish your sightseeing early on the 20th (Tue) to allow enough time to drive to Colonia del Sacramento.

Things to do in Montevideo

Shopping · Neighborhoods · Wineries · Historic Sites

Side Trip

Colonia del Sacramento, Uruguay

— 1 night
Sleepy cobbled streets lined with pastel-colored houses lead down to the water in Colonia del Sacramento.
On the 21st (Wed), take in the exciting artwork at Casa Carbajal Arte y Objetos, take in the views from Puerta de la Ciudadela, take an in-depth tour of Museo Portugues, don't miss a visit to La Calle de los Suspiros, then visit a coastal fixture at Colonia del Sacramento Lighthouse, and finally wander the streets of Barrio Historico.

For reviews, other places to visit, photos, and other tourist information, you can read our Colonia del Sacramento road trip planning site.

Traveling by car from Montevideo to Colonia del Sacramento takes 3 hours. Alternatively, you can take a bus. July in Colonia del Sacramento sees daily highs of 17°C and lows of 9°C at night. Cap off your sightseeing on the 21st (Wed) early enough to catch the ferry to Buenos Aires.

Things to do in Colonia del Sacramento

Museums · Historic Sites · Neighborhoods · Shopping

Buenos Aires, Argentina

— 4 nights

Queen of La Plata

Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for historic sites, nightlife, and parks. Your plan includes some of its best attractions: take a stroll through Puerto Madero, explore the engaging exhibits at Museo de los Ninos, get a sense of history and politics at Casa Rosada, and take in nature's colorful creations at Parque 3 de Febrero.

To see other places to visit, where to stay, photos, and more tourist information, use the Buenos Aires travel planning tool.

Getting from Colonia del Sacramento to Buenos Aires by ferry takes about 2 hours. Expect a daytime high around 17°C in July, and nighttime lows around 10°C. Cap off your sightseeing on the 25th (Sun) early enough to travel to Santiago.

Things to do in Buenos Aires

Museums · Historic Sites · Neighborhoods · Parks

Santiago, Chile

— 4 nights

City of the Island Hills

Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Step out of Santiago to go to Valle Nevado and see Valle Nevado - Ski Resort Chile, which is approximately 1h 35 min away. The adventure continues: tour the pleasant surroundings at San Cristóbal Hill, walk around Cerro Santa Lucia, hit the slopes at La Parva Ski Resort, and stop by Patio Bellavista.

To see traveler tips, other places to visit, photos, and other tourist information, read our Santiago trip planner.

You can fly from Buenos Aires to Santiago in 6 hours. Other options are to drive; or take a bus. Traveling from Buenos Aires to Santiago, you'll gain 1 hour due to the time zone difference. Finish up your sightseeing early on the 29th (Thu) so you can go by car to Valparaiso.

Things to do in Santiago

Parks · Winter Sports · Outdoors · Museums

Side Trip

Valparaiso, Chile

— 1 night

Jewel of the Pacific

Navigating through a maze of colorful streets winding up and down steep hills remains an integral part of any Valparaiso tour.
On the 30th (Fri), examine the collection at La Sebastiana, get the lay of the land with Walking tours, and then don't miss a visit to Flower Clock (Reloj de Flores).

For where to stay, traveler tips, ratings, and more tourist information, use the Valparaiso day trip planner.

Getting from Santiago to Valparaiso by car takes about 1.5 hours. Other options: take a bus. July in Valparaiso sees daily highs of 17°C and lows of 9°C at night. Wrap up your sightseeing on the 30th (Fri) to allow time to travel to San Pedro de Atacama.

Things to do in Valparaiso

Tours · Museums

Side Trip

San Pedro de Atacama, Chile

— 4 nights
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Go for a jaunt from San Pedro de Atacama to Antofagasta to see Salar de Atacama about 1h 35 min away. There's still lots to do: witness a stunning natural landmark at Geyser del Tatio, take in the dramatic natural features at Valle De La Luna, look for all kinds of wild species at Río Putana, and don't miss a visit to Mirador de Kari, Piedra del Coyote.

To find maps, reviews, where to stay, and more tourist information, use the San Pedro de Atacama trip maker website.

Getting from Valparaiso to San Pedro de Atacama by flight takes about 6.5 hours. Other options: drive; or take a bus. When traveling from Valparaiso in July, plan for somewhat warmer days in San Pedro de Atacama, with highs around 25°C, while nights are slightly colder with lows around 0°C. Wrap up your sightseeing by early afternoon on the 3rd (Tue) to allow time for the car ride to Uyuni.

Things to do in San Pedro de Atacama

Parks · Nature · Wildlife · Tours

Side Trips

Uyuni, Bolivia

— 1 night
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
On the 4th (Wed), make a trip to Plaza Arce, then learn more about the world around you at Museo Arquecologia y Antropologico de los Andes Meridionales, then explore the striking landscape at Salar de Uyuni, and finally examine the collection at Train Cemetery.

To see more things to do, maps, photos, and more tourist information, use the Uyuni trip itinerary app.

You can drive from San Pedro de Atacama to Uyuni in 9.5 hours. Alternatively, you can take a bus. When traveling from San Pedro de Atacama in August, plan for much colder days in Uyuni, with highs around 7°C, while nights are a bit warmer with lows around 7°C. Finish your sightseeing early on the 4th (Wed) to allow enough time to travel to La Paz.

Things to do in Uyuni

Parks · Museums · Nature

La Paz, Bolivia

— 2 nights

City that Touches the Sky

Take a moment to catch your breath as you commence your holiday in La Paz.
On the 5th (Thu), get the lay of the land with Walking tours, make a trip to Mercado de Las Brujas, then look for gifts at Unique, and finally experience the excitement of Andean Culture Distillery. Keep things going the next day: push the limits with an extreme tour, don't miss a visit to Calle Sagarnaga, and then don't miss a visit to Mi Teleferico.

To see ratings, traveler tips, more things to do, and other tourist information, use the La Paz trip itinerary maker app.

You can fly from Uyuni to La Paz in 3 hours. Other options are to drive; or take a bus. Traveling from Uyuni in August, you will find days in La Paz are a bit warmer (18°C), and nights are little chillier (-3°C). Wrap up your sightseeing on the 6th (Fri) early enough to travel to Cusco.

Things to do in La Paz

Tours · Outdoors · Shopping · Breweries & Distilleries

Cusco, Peru

— 3 nights

Imperial City

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Step out of Cusco with an excursion to Salinas de Maras in Maras--about 1h 25 min away. Spend the 8th (Sun) wandering through the wild on a nature and wildlife tour. The adventure continues: admire the landmark architecture of Centro Historico De Cusco, explore the world behind art at Museo de Arte Precolombino, pause for some serene contemplation at Cusco Cathedral, and gain insight with exploor.

For photos, where to stay, reviews, and other tourist information, go to the Cusco travel itinerary planner.

Traveling by flight from La Paz to Cusco takes 4.5 hours. Alternatively, you can drive; or take a bus. The time zone changes from Bolivia Time (BOT) to Peru Standard Time (PET), which is usually a -1 hour difference. Traveling from La Paz in August, expect Cusco to be somewhat warmer, temps between 24°C and 2°C. Finish your sightseeing early on the 9th (Mon) so you can travel to Machu Picchu.

Things to do in Cusco

Historic Sites · Tours · Outdoors · Wildlife

Side Trip

Machu Picchu, Peru

— 1 night
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Kick off your visit on the 10th (Tue): steep yourself in history at Santuario Historico de Machu Picchu, then relax and rejuvenate at SPA Rocas Sagradas, and then look for gifts at Mapi Art.

To find photos, where to stay, other places to visit, and tourist information, read our Machu Picchu trip maker site.

Traveling by combination of bus and train from Cusco to Machu Picchu takes 4 hours. Alternatively, you can take a train; or drive. Wrap up your sightseeing on the 10th (Tue) early enough to travel to Cusco.

Things to do in Machu Picchu

Historic Sites · Spas · Shopping

Cusco, Peru

— 1 night

Imperial City

On the 11th (Wed), contemplate in the serene atmosphere at Qorikancha, then contemplate the long history of Sacsayhuaman, and then steep yourself in history at Plaza de Armas.

For ratings, reviews, and more tourist information, use the Cusco online trip planner.

Do a combination of train and bus from Machu Picchu to Cusco in 4 hours. Alternatively, you can take a train; or drive. Finish your sightseeing early on the 11th (Wed) to allow enough time to travel back home.

Things to do in Cusco

Historic Sites