28 days in Colombia, Peru & Antofagasta Itinerary

28 days in Colombia, Peru & Antofagasta Itinerary

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Route & dates

28 days in Colombia, Peru & Antofagasta Itinerary

Start: Dublin, Ireland
Fly:  20​h
1
Cartagena, Colombia
— 3 nights
Drive:  3​h 30​min
2
Santa Marta, Colombia
— 4 nights
Fly:  4​h 15​min
3
Medellin, Colombia
— 5 nights
Fly:  7​h 15​min
4
Cusco, Peru
— 3 nights
+2
Bus + Foot + Train:  3​h 15​min
5
Machu Picchu, Peru
— 3 nights
+2
Train + Foot + Bus:  3​h 15​min
6
Cusco, Peru
— 2 nights
Fly:  1​h 45​min
7
Lima, Peru
— 3 nights
Fly:  7​h
8
Antofagasta, Chile
— 2 nights
Fly:  25​h
End: Dublin, Ireland


Learn more about your trip

3
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Kick off your visit on the 27th (Fri): make a trip to Plaza de La Trinidad, contemplate in the serene atmosphere at Templo de Santo Domingo, kick back and relax at Playa Puntilla, then identify plant and animal life at Aviario Nacional de Colombia, and finally make a trip to Centro de Convenciones Cartagena de Indias. Get ready for a full day of sightseeing on the next day: get outside with Bomba Beach Club and then wander the streets of Centro Historico.

To see maps, photos, where to stay, and tourist information, use the Cartagena attractions planner.

Dublin, Ireland to Cartagena is an approximately 20-hour flight. You can also do a combination of flight and bus. You'll gain 5 hours traveling from Dublin to Cartagena due to the time zone difference. Plan for much warmer temperatures traveling from Dublin in September, with highs in Cartagena at 38°C and lows at 30°C. You'll have a few hours on the 29th (Sun) to wrap things up before traveling to Santa Marta.

Things to do in Cartagena

Outdoors Historic Sites Parks

Side Trip

Isla Baru
Highlights from your plan
Aviario Nacional de Colombia ©
Aviario Nacional de Colombia
Templo de Santo Domingo ©
Templo de Santo Domingo
Castillo de San Felipe de Barajas ©
Castillo de San Felipe de Barajas

4
nights
Santa Marta, Colombia

Many visitors begin their Santa Marta holiday, surrounded by urban clutter and heavy traffic, expecting little from the city in terms of historical importance.
Discover out-of-the-way places like Scuba & Snorkeling and El Dorado Bird Reserve. You'll enjoy a bit of beach vacationing at Playa Blanca and Playa Neguanje. The adventure continues: explore the wealth of natural beauty at Parque Nacional Natural Tayrona, make a trip to El Amanuense Libros & Cafe, steep yourself in history at Paseo El Camellon, and look for gifts at Yo Amo Santa Marta.

To find where to stay, ratings, traveler tips, and tourist information, you can read our Santa Marta trip planner .

Getting from Cartagena to Santa Marta by car takes about 3.5 hours. Other options: take a bus. In September, daily temperatures in Santa Marta can reach 39°C, while at night they dip to 29°C. Wrap up your sightseeing on the 3rd (Thu) to allow time to travel to Medellin.

Things to do in Santa Marta

Parks Nature Outdoors

Side Trips

Scuba & Snorkeling, El Dorado Bird Reserve
Highlights from your plan
Scuba & Snorkeling
Parque Nacional Natural Tayrona ©
Parque Nacional Natural Tayrona
Playa Blanca ©
Playa Blanca

5
nights
Medellin, Colombia

Medellin ©
Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Step off the beaten path and head to Piedra Del Penol and Parque Arvi. Visiting Parasailing & Paragliding and Ciclovia will get you outdoors. Venture out of the city with trips to Guatape (Iglesia de Nuestra Senora del Carmen, ALTITUDE, & more). There's lots more to do: get engrossed in the history at Museo de Antioquia, steep yourself in history at Pueblito Paisa, take a memorable drive along 2000m Descent and more, and look and learn at Planetario de Medellin.

To find ratings, reviews, more things to do, and more tourist information, you can read our Medellin online itinerary planner .

Traveling by flight from Santa Marta to Medellin takes 4.5 hours. Alternatively, you can do a combination of bus and flight; or drive. Traveling from Santa Marta in October, expect Medellin to be a bit cooler, temps between 32°C and 20°C. Wrap up your sightseeing on the 8th (Tue) early enough to travel to Cusco.

Things to do in Medellin

Parks Outdoors Museums

Side Trip

Guatape
Highlights from your plan
Piedra Del Penol ©
Piedra Del Penol
Parque Arvi ©
Parque Arvi
Parasailing & Paragliding

3
nights
Cusco, Peru

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Satisfy your inner culture vulture at Sacsayhuaman and Sacred Valley of the Incas. Explore hidden gems such as Horseback Riding Tours and San Pedro Apostol de Andahuaylillas. There's lots more to do: explore the striking landscape at Cerro Colorado Vinicunca, relax and float downstream with a rafting and tubing tour, relax and rejuvenate at some of the best spas, and contemplate the long history of Tipon.

To see ratings and tourist information, you can read our Cusco trip website .

Traveling by flight from Medellin to Cusco takes 7.5 hours. Alternatively, you can drive; or take a bus. While traveling from Medellin, expect little chillier days and much colder nights in Cusco, ranging from highs of 24°C to lows of 7°C. Wrap up your sightseeing on the 11th (Fri) early enough to travel to Machu Picchu.

Things to do in Cusco

Tours Outdoors Historic Sites

Side Trips

San Pedro Apostol de Andahuaylillas, Sacred Valley of the Incas
Highlights from your plan
Horseback Riding Tours
Sacsayhuaman ©
Sacsayhuaman
Kayaking & Canoeing

3
nights
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Start off your visit on the 12th (Sat): explore the ancient world of Intipuncu, steep yourself in history at Santuario Historico de Machu Picchu, then examine the collection at Museo de Sitio Manuel Chavez Ballon, and finally identify plant and animal life at Los Jardines de Mandor. Here are some ideas for day two: witness a stunning natural landmark at Banos Termales de Cocalmayo, then delve into the distant past at Winay Wayna, and then look for all kinds of wild species at Jardin Botanico en Machu Pichu.

To find ratings, where to stay, reviews, and more tourist information, you can read our Machu Picchu travel site .

Getting from Cusco to Machu Picchu by combination of bus and train takes about 3.5 hours. Other options: take a train; or drive. Finish your sightseeing early on the 14th (Mon) to allow enough time to travel to Cusco.

Things to do in Machu Picchu

Historic Sites Parks Wildlife

Side Trip

Banos Termales de Cocalmayo
Highlights from your plan
Intipuncu ©
Intipuncu
Santuario Historico de Machu Picchu ©
Los Jardines de Mandor ©
Los Jardines de Mandor

2
nights
Cusco, Peru

Cusco ©
Escape the urban bustle at Montana de Siete Colores and Humantay Lake. Get a sense of the local culture at Q'enqo and Nature & Wildlife Tours. Explore the numerous day-trip ideas around Cusco: Humedales de Huasao (in Oropesa) and Salinas de Maras (in Maras). See even more of Cusco: contemplate the long history of Plaza de Armas, trek along exploor, and admire the masterpieces at Museo y Catacumbas Del Convento San Francisco de Asis Del Cusco.

Start your trip to Cusco by creating a personalized itinerary on Inspirock.

You can do a combination of train and bus from Machu Picchu to Cusco in 3.5 hours. Other options are to take a train; or drive. Finish your sightseeing early on the 16th (Wed) to allow enough time to travel to Lima.

Things to do in Cusco

Parks Nature Wildlife

Side Trips

Salinas de Maras, Huasao Bosque de los Ents, del Senor de los Anillos
Highlights from your plan
exploor ©
exploor
Humantay Lake ©
Humantay Lake
Q'enqo ©
Q'enqo

3
nights
Lima, Peru

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Get outdoors at Nor Yauyos-Cochas Landscape Reserve and Nature & Wildlife Tours. Step off the beaten path and head to Huaca Pucllana and MALI - Museo de Arte de Lima. And it doesn't end there: take in the architecture and atmosphere at Iglesia y Convento de San Francisco, wander the streets of San Isidro, examine the collection at Museo del Automovil Coleccion Nicolini, and admire the masterpieces at Museo Pedro de Osma.

To see traveler tips, maps, where to stay, and other tourist information, read our Lima trip maker website .

Getting from Cusco to Lima by flight takes about 2 hours. Other options: drive; or take a bus. Traveling from Cusco in October, you can expect nighttime temperatures to be a bit warmer in Lima, with lows of 19°C. Wrap up your sightseeing on the 19th (Sat) early enough to travel to Antofagasta.

Things to do in Lima

Wildlife Historic Sites Museums
Highlights from your plan
Nature & Wildlife Tours
Huaca Pucllana ©
Huaca Pucllana
MALI - Museo de Arte de Lima ©
MALI - Museo de Arte de Lima

2
nights
Antofagasta, Chile

Antofagasta ©
A major port city of northern Chile, Antofagasta officially became part of the country in 1904, when the Treaty of Peace and Friendship between Chile and Bolivia formerly enshrined a new regional status quo after the War of the Pacific (1879-83).
Escape the urban bustle at Desierto de Atacama and Scuba & Snorkeling. Rio Grande and Museo Ferroviario de Antofagasta are good opportunities to explore the local culture. There's lots more to do: take in the dramatic natural features at La Portada, take in the views from Muelle Salitrero Compania Melbourne Clark, see where the action happens at Estadio Regional de Antofagasta, and take in the architecture and atmosphere at Iglesia Corazon de Maria.

To see reviews, maps, other places to visit, and other tourist information, use the Antofagasta online tour itinerary planner .

The Route module can help you plan travel from Lima to Antofagasta. Traveling from Lima to Antofagasta, you'll lose 1 hour due to the time zone difference. While traveling from Lima, expect little chillier days and about the same nights in Antofagasta, ranging from highs of 20°C to lows of 16°C. Finish your sightseeing early on the 22nd (Tue) to allow enough time to travel back home.

Things to do in Antofagasta

Tours Wildlife Outdoors
Highlights from your plan
La Portada ©
La Portada
Centro Cultural Estación Antofagasta ©
Iglesia Corazon de Maria ©
Iglesia Corazon de Maria

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