27 days in Mexico & South America Itinerary

27 days in Mexico & South America Itinerary

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Route & dates

27 days in Mexico & South America Itinerary

Start: Charlotte, United States
Drive + Fly:  10 h 15 min
1
Monterrey, Mexico
— 3 nights
Fly:  4 h 30 min
2
Cancun, Mexico
— 4 nights
Fly:  6 h 30 min
3
Lima, Peru
— 1 night
train:  7 h
4
Huaraz, Peru
— 2 nights
train:  7 h
5
Lima, Peru
— 4 nights
Fly:  1 h 45 min
6
Cusco, Peru
— 3 nights
Fly:  11 h 30 min
7
Temuco, Chile
— 2 nights
Fly:  7 h 15 min
8
Mendoza, Argentina
— 3 nights
Fly:  3 h 30 min
9
Buenos Aires, Argentina
— 2 nights
Fly:  15 h 45 min
End: Charlotte, United States

3
nights
Monterrey, Mexico

Monterrey ©
An industrial powerhouse and a major transportation hub close to the Texas border, Monterrey offers visitors a blend of culture, art, and history.
Your day-by-day itinerary now includes Parque la Huasteca, Gran Plaza o Macroplaza and Paseo San Pedro Centro Comercial. Get ready for a full day of sightseeing on the 14th (Sat): appreciate the extensive heritage of Gran Plaza o Macroplaza, take your sightseeing to a higher altitude at Parque la Huasteca, then browse the different shops at Paseo San Pedro Centro Comercial, and finally explore the engaging exhibits at Museo del Dulce.

To find more things to do, traveler tips, and more tourist information, use the Monterrey trip itinerary site .

Charlotte, USA to Monterrey is an approximately 10.5-hour flight. Traveling from Charlotte to Monterrey, you'll gain 1 hour due to the time zone difference. On the 16th (Mon), you'll have the morning to explore before heading off to Cancun.

Things to do in Monterrey

Parks Shopping Historic Sites
Highlights from your plan
Parque la Huasteca ©
Parque la Huasteca
Gran Plaza o Macroplaza ©
Gran Plaza o Macroplaza
Museo del Dulce ©
Museo del Dulce

4
nights
Cancun, Mexico

Few destinations in Mexico dazzle visitors quite like Cancun, a modern resort town filled with glitzy hotels sitting on picturesque and well-developed Caribbean beaches.
Your cultural itinerary includes sights like Cobá Zona Arqueológica Cobá and El Rey Archaeological Zone. Escape the urban bustle at Scuba & Snorkeling and Swim with Dolphins. And it doesn't end there: browse the eclectic array of goods at Mercado 28, appreciate the history behind Monumento a los Ninos Heroes, and indulge in some personalized pampering at some of the best spas.

To see maps, ratings, photos, and more tourist information, use the Cancun trip itinerary planner .

Getting from Monterrey to Cancun by flight takes about 4.5 hours. Other options: drive; or take a bus. The time zone difference when traveling from Monterrey to Cancun is 1 hour. In May in Cancun, expect temperatures between 86°F during the day and 75°F at night. Finish your sightseeing early on the 20th (Fri) to allow enough time to travel to Lima.

Things to do in Cancun

Tours Outdoors Wildlife

Side Trips

Cobá Zona Arqueológica Cobá, Scuba & Snorkeling
Highlights from your plan
Scuba & Snorkeling
Cobá Zona Arqueológica Cobá ©
Cobá Zona Arqueológica Cobá
Swim with Dolphins

1
night
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
On the 20th (Fri), contemplate the long history of Huaca Pucllana and then take an in-depth tour of Museo Larco.

Before you visit Lima, use our trip planner to discover what you can do and see there.

You can fly from Cancun to Lima in 6.5 hours. Expect slightly colder temperatures when traveling from Cancun in May; daily highs in Lima reach 73°F and lows reach 65°F. You'll have a few hours on the 21st (Sat) to wrap things up before traveling to Huaraz.

Things to do in Lima

Historic Sites Museums
Highlights from your plan
Huaca Pucllana ©
Huaca Pucllana
Museo Larco ©
Museo Larco

2
nights
Huaraz, Peru

Huaraz ©
One of the main cities in the Peruvian Andes, Huaraz mainly draws those seeking adventure out in the landscape.
On the 22nd (Sun), get engrossed in the history at Museo Arqueologico de Ancash "Augusto Soriano Infante" and then explore the activities along Laguna Churup.

To find ratings, traveler tips, and other tourist information, use the Huaraz visit planner .

Traveling by flight from Lima to Huaraz takes 2 hours. Alternatively, you can drive; or do a combination of flight and car. Expect a bit cooler evenings in Huaraz when traveling from Lima in May, with lows around 50°F. You'll have a few hours on the 23rd (Mon) to wrap things up before traveling to Lima.

Things to do in Huaraz

Parks Nature Museums

Side Trip

Laguna Churup
Highlights from your plan
Laguna Churup ©
Laguna Churup
RUBRIX ©
RUBRIX

4
nights
Lima, Peru

Get outdoors at Nature & Wildlife Tours and Parque La Felicidad. Get some cultural insight at Museo Larco and Huaca Pucllana. See even more of Lima: wander the streets of Miraflores, admire the local landmark of Plaza de Armas (Plaza Mayor), visit Barranco, and take in the spiritual surroundings of San Pedro Church (Iglesia de San Pedro).

For more things to do, where to stay, reviews, and more tourist information, read our Lima trip builder app .

Fly from Huaraz to Lima in 2 hours. Alternatively, you can drive; or do a combination of car and flight. Traveling from Huaraz in May, you can expect nighttime temperatures to be a bit warmer in Lima, with lows of 65°F. You will have some time to spend on the 27th (Fri) before leaving for Cusco.

Things to do in Lima

Outdoors Historic Sites Tours
Highlights from your plan
Nature & Wildlife Tours
Museo Larco ©
Museo Larco

3
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Take a break from the city and head to Salinas de Maras and Nature & Wildlife Tours. Get a sense of the local culture at Sacsayhuaman and Iglesia De Santo Domingo. There's still lots to do: steep yourself in history at Plaza de Armas, take an in-depth tour of Museo Quechua, stroll through exploor, and see the interesting displays at Museo de Arte Precolombino.

For photos, traveler tips, maps, and other tourist information, use the Cusco road trip planner.

Fly from Lima to Cusco in 2 hours. Alternatively, you can drive; or take a bus. Traveling from Lima in May, you can expect nighttime temperatures to be much colder in Cusco, with lows of 39°F. You'll have a few hours on the 30th (Mon) to wrap things up before traveling to Temuco.

Things to do in Cusco

Historic Sites Tours Outdoors

Side Trip

Salinas de Maras
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Qorikancha ©
Qorikancha
Salinas de Maras ©
Salinas de Maras

2
nights
Temuco, Chile

Temuco ©
Temuco developed into a major Chilean city because of a forestry and livestock boom the region experienced during the early decades of the 20th century.
On the 31st (Tue), witness a stunning natural landmark at Los Pozones and then examine the collection at Museo Nacional Ferroviario Pablo Neruda de Temuco. Keep things going the next day: take in the architecture and atmosphere at Iglesia Catedral de Temuco and then explore the wealth of natural beauty at Monumento Natural Cerro Nielol.

To see traveler tips, where to stay, maps, and other tourist information, use the Temuco road trip planner.

Use the Route module to find suitable travel options from Cusco to Temuco. The time zone difference moving from Peru Time (PET) to Chile Time (CLT) is 1 hour. On the 2nd (Thu), you'll have the morning to explore before heading off to Mendoza.

Things to do in Temuco

Parks Nature Museums

Side Trip

Los Pozones
Highlights from your plan
Los Pozones ©
Los Pozones
Iglesia Catedral de Temuco ©
Iglesia Catedral de Temuco

3
nights
Mendoza, Argentina

Mendoza ©
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Get some cultural insight at Bodega Tierras Altas and Bodegas Salentein. Get out of town with these interesting Mendoza side-trips: Maipu (Casa El Enemigo & Bodega CarinaE). Next up on the itinerary: take your sightseeing to a higher altitude at Parque Provincial Aconcagua, learn about winemaking at Bodega Ruca Malen, walk around Parque General San Martin, and take in the architecture and atmosphere at Santuario Virgen de Lourdes.

For where to stay, photos, other places to visit, and more tourist information, read our Mendoza tour itinerary planning app .

Explore your travel options from Temuco to Mendoza with the Route module. Traveling from Temuco to Mendoza, you'll lose 1 hour due to the time zone difference. In June in Mendoza, expect temperatures between 61°F during the day and 37°F at night. Finish up your sightseeing early on the 5th (Sun) so you can travel to Buenos Aires.

Things to do in Mendoza

Wineries Parks Nature

Side Trips

Maipu, Santuario Virgen de Lourdes, Bodegas Salentein
Highlights from your plan
Bodega Tierras Altas ©
Bodega Tierras Altas
Parque Provincial Aconcagua ©
Parque Provincial Aconcagua
Bodega Roberto Bonfanti ©
Bodega Roberto Bonfanti

2
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
On the 6th (Mon), make a trip to Cemiterio de Recoleta, then admire the natural beauty at Parque 3 de Febrero, then admire the masterpieces at Museo de Arte Latinoamericano de Buenos Aires, and finally wander the streets of Puerto Madero.

Start your trip to Buenos Aires by creating a personalized itinerary on Inspirock.

You can fly from Mendoza to Buenos Aires in 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from Mendoza in June, Buenos Aires is a bit warmer at night with lows of 49°F. You will have some time to spend on the 7th (Tue) before leaving for home.

Things to do in Buenos Aires

Museums Historic Sites Shopping
Highlights from your plan
Puerto Madero ©
Puerto Madero
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero