26 days in Uruguay, Argentina & Chile Itinerary

26 days in Uruguay, Argentina & Chile Itinerary

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Route & dates

26 days in Uruguay, Argentina & Chile Itinerary

Start: Uberlandia, Brazil
Fly + bus:  11​h
1
Punta del Este, Uruguay
— 2 nights
Drive:  2​h 30​min
2
Punta del Diablo, Uruguay
— 2 nights
Drive:  4​h
3
Montevideo, Uruguay
— 2 nights
Drive:  2​h 45​min
4
Colonia del Sacramento, Uruguay
— 2 nights
ferry:  1​h
5
Buenos Aires, Argentina
— 3 nights
Fly:  3​h 30​min
6
Mendoza, Argentina
— 3 nights
Fly + bus:  2​h
7
Santiago, Chile
— 3 nights
bus:  1​h 30​min
8
Valparaiso, Chile
— 2 nights
+2
shuttle + Fly + shuttle:  6​h 30​min
9
San Pedro de Atacama, Chile
— 6 nights
Drive + Fly:  17​h
End: Uberlandia, Brazil

2
nights
Punta del Este, Uruguay

Punta del Este ©
With plenty of modern casinos, well-developed beaches, chic restaurants, and upscale hotels, Punta del Este vacations draw visitors from Argentina, Brazil, and beyond.
Kick off your visit on the 2nd (Wed): kick back and relax at Playa el Emir, enjoy the sand and surf at Playa Brava, and then do a tasting at Vina Eden. On the 3rd (Thu), you'll have a packed day of sightseeing: admire the landmark architecture of Museo – Taller de Casapueblo, enjoy the sand and surf at Playa Mansa, then examine the collection at Museo del Mar, and finally enjoy the sand and surf at Playa Mansa.

To see where to stay, more things to do, maps, and other tourist information, read Punta del Este holiday planner .

Uberlandia, Brazil to Punta del Este is an approximately 11-hour combination of flight and bus. You can also drive; or take a bus. While traveling from Uberlandia, expect much colder days and a bit cooler nights in Punta del Este, ranging from highs of 20°C to lows of 15°C. Cap off your sightseeing on the 3rd (Thu) early enough to go by car to Punta del Diablo.

Things to do in Punta del Este

Parks Outdoors Beaches

Side Trips

Museo – Taller de Casapueblo, Playa Mansa
Highlights from your plan
Playa el Emir ©
Playa el Emir
Playa Brava ©
Playa Brava
Museo – Taller de Casapueblo ©
Museo – Taller de Casapueblo

2
nights
Punta del Diablo, Uruguay

Punta del Diablo ©
Formerly a sleepy little fishing town, Punta del Diablo has become a popular seaside getaway with a wealth of attractions natural and manmade.
Kick off your visit on the 4th (Fri): kick back and relax at Las Achiras Beach, then enjoy the sand and surf at Cerro Verde e Islas de la Coronilla, and then steep yourself in history at Fortress of Santa Teresa. Keep things going the next day: enjoy the sea views from Lighthouse of Cabo Polonio and then take in the dramatic natural features at Medanos de la Barra de Valizas.

To see traveler tips, where to stay, and tourist information, refer to the Punta del Diablo trip planner.

Drive from Punta del Este to Punta del Diablo in 2.5 hours. Alternatively, you can take a bus. Due to the time zone difference, you'll gain 1 hour traveling from Punta del Este to Punta del Diablo. Finish up your sightseeing early on the 5th (Sat) so you can go by car to Montevideo.

Things to do in Punta del Diablo

Parks Wildlife Outdoors

Side Trips

Rocha, Lighthouse of Cabo Polonio, Medanos de la Barra de Valizas, Cerro Verde e Islas de la Coronilla
Highlights from your plan
Medanos de la Barra de Valizas ©
Medanos de la Barra de Valizas
Fortress of Santa Teresa ©
Fortress of Santa Teresa
Lighthouse of Cabo Polonio ©
Lighthouse of Cabo Polonio

2
nights
Montevideo, Uruguay

Montevideo ©
With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
Kick off your visit on the 6th (Sun): enjoy the sand and surf at Balneario Kiyu, then do a tasting at Pizzorno Family Estates, and then take an in-depth tour of Casa Quinta de Luis Alberto de Herrera. Get ready for a full day of sightseeing on the next day: ponder the world of politics at Estevez Palace, examine the collection at Museo Casa de Gobierno, examine the collection at Museo del Gaucho y de la Moneda, then take in the architecture and atmosphere at Iglesia de las Carmelitas, and finally gear up at Orange Bike.

To find reviews, more things to do, traveler tips, and tourist information, refer to the Montevideo tour site .

You can drive from Punta del Diablo to Montevideo in 4 hours. Alternatively, you can take a bus. The time zone changes from Amazon Time to Uruguay Time, which is usually a 1 hour difference. October in Montevideo sees daily highs of 23°C and lows of 13°C at night. Finish up your sightseeing early on the 7th (Mon) so you can go by car to Colonia del Sacramento.

Things to do in Montevideo

Parks Outdoors Beaches

Side Trips

Pizzorno Family Estates, Balneario Kiyu
Highlights from your plan
Pizzorno Family Estates ©
Pizzorno Family Estates
Iglesia de las Carmelitas ©
Iglesia de las Carmelitas
Museo Casa de Gobierno ©
Museo Casa de Gobierno

2
nights
Colonia del Sacramento, Uruguay

Colonia del Sacramento ©
Sleepy cobbled streets lined with pastel-colored houses lead down to the water in Colonia del Sacramento.
Start off your visit on the 8th (Tue): see the interesting displays at Granja Colonia, take a stroll through Barrio Historico, then take a stroll through Plaza Mayor, then visit a coastal fixture at Colonia del Sacramento Lighthouse, and finally delve into the distant past at Convento de San Francisco. On the next day, explore the activities along Rio de la Plata, examine the collection at Museo de Azulejos, then explore the ancient world of Bastion de San Miguel, and finally take in the waterfront at Paseo de San Gabriel.

To find traveler tips, maps, photos, and tourist information, go to the Colonia del Sacramento online route planner .

Traveling by car from Montevideo to Colonia del Sacramento takes 3 hours. Alternatively, you can take a bus. October in Colonia del Sacramento sees daily highs of 24°C and lows of 15°C at night. Wrap up your sightseeing on the 9th (Wed) early enough to ride a ferry to Buenos Aires.

Things to do in Colonia del Sacramento

Historic Sites Parks Nature
Highlights from your plan
Barrio Historico ©
Barrio Historico
Plaza Mayor ©
Plaza Mayor
Rio de la Plata ©
Rio de la Plata

3
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Museum-lovers will get to explore Museo de La Plata and Centro Ana Frank. Step off the beaten path and head to Catedral de San Isidro and Delta El Tigre. Get out of town with these interesting Buenos Aires side-trips: Peru Beach (in Acassuso), Villa Ocampo (in San Isidro) and Basilica de Lujan (in Lujan). There's lots more to do: take a stroll through Puerto Madero, examine the collection at Fragata ARA Sarmiento, pause for some serene contemplation at Basilica del Santisimo Sacramento, and take in nature's colorful creations at Parque 3 de Febrero.

Inspirock's itinerary builder makes planning a Buenos Aires trip simple and quick.

Ride a ferry from Colonia del Sacramento to Buenos Aires in an hour. Alternatively, you can take a bus. In October, daily temperatures in Buenos Aires can reach 24°C, while at night they dip to 17°C. Finish up your sightseeing early on the 12th (Sat) so you can travel to Mendoza.

Things to do in Buenos Aires

Outdoors Parks Historic Sites

Side Trips

San Isidro, Museo de La Plata, Delta El Tigre, Peru Beach, Basilica de Lujan
Highlights from your plan
Puerto Madero ©
Puerto Madero
Catedral de San Isidro ©
Catedral de San Isidro
Villa Ocampo ©
Villa Ocampo

3
nights
Mendoza, Argentina

Mendoza ©
Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Step off the beaten path and head to Bodega Tierras Altas and Vina Cobos. Do some cultural sightseeing at Bodega Renacer and Casarena Bodega y Vinedos. When in Mendoza, make a side trip to see Familia Zuccardi in Maipu, approximately 44 minutes away. The adventure continues: do a tasting at Bodega Carmelo Patti and make a trip to Antigua Bodega Giol.

To find more things to do, where to stay, other places to visit, and more tourist information, read our Mendoza journey planning site .

Fly from Buenos Aires to Mendoza in 3.5 hours. Alternatively, you can drive; or take a bus. Traveling from Buenos Aires in October, expect nights in Mendoza to be a bit cooler, around 13°C, while days are somewhat warmer, around 28°C. Finish your sightseeing early on the 15th (Tue) so you can travel to Santiago.

Things to do in Mendoza

Wineries Historic Sites

Side Trip

Maipu
Highlights from your plan
Bodega Chandon ©
Bodega Chandon
Bodega Tierras Altas ©
Bodega Tierras Altas
Bodega Carmelo Patti ©
Bodega Carmelo Patti

3
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Deepen your sense of the past at sights like Santuario de la Inmaculada Concepcion and Castillo Hidalgo. Museum-lovers will appreciate Museo Interactivo Mirador and National Museum of History. Explore the numerous day-trip ideas around Santiago: Vina Undurraga (in Talagante) and Vina Santa Rita (in Buin). And it doesn't end there: take some stellar pictures from San Cristóbal Hill, take a stroll through Barrio Italia, examine the collection at La Chascona, and do a tasting at Santa Carolina.

To find more things to do, where to stay, other places to visit, and tourist information, go to the Santiago vacation builder app .

Traveling by combination of flight and bus from Mendoza to Santiago takes 2 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Mendoza to Santiago is minus 1 hour. Wrap up your sightseeing on the 18th (Fri) early enough to take a bus to Valparaiso.

Things to do in Santiago

Wineries Museums Parks

Side Trips

Vina Santa Rita, Vina Undurraga
Highlights from your plan
Vina Santa Rita ©
Vina Santa Rita
Vina Undurraga ©
Vina Undurraga
Santuario de la Inmaculada Concepcion ©

2
nights
Valparaiso, Chile

Valparaiso ©
Navigating through a maze of colorful streets winding up and down steep hills remains an integral part of any Valparaiso tour.
Kick off your visit on the 19th (Sat): learn about winemaking at Bodegas RE, then learn about all things military at Museo Maritimo Nacional, then get to know the fascinating history of Paseo Gervasoni, and finally see the interesting displays at La Sebastiana. Get ready for a full day of sightseeing on the next day: learn about winemaking at Kingston Family Vineyards, admire the masterpieces at Palacio Baburizza, then get to know the fascinating history of Paseo Yugoslavo, and finally get engrossed in the history at Museo Mirador Lukas.

Before you visit Valparaiso, use our trip planner to discover what you can do and see there.

Take a bus from Santiago to Valparaiso in 1.5 hours. Alternatively, you can drive. In October in Valparaiso, expect temperatures between 20°C during the day and 13°C at night. Finish your sightseeing early on the 20th (Sun) to allow enough time to travel to San Pedro de Atacama.

Things to do in Valparaiso

Museums Wineries Historic Sites

Side Trip

Casablanca
Highlights from your plan
Museo Maritimo Nacional ©
Museo Maritimo Nacional
Palacio Baburizza ©
Palacio Baburizza
Paseo Gervasoni ©
Paseo Gervasoni

6
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Visiting Piedras Rojas and Laguna Chaxa will get you outdoors. Satisfy your inner culture vulture at Pukara de Quitor and Museo del Meteorito. When in San Pedro de Atacama, make a side trip to see Cementerio de Toconao in Toconao, approximately 38 minutes away. And it doesn't end there: contemplate the geological forces at Lascar, get outside with Quebrada del Diablo, identify plant and animal life at Valle Arcoiris, and contemplate in the serene atmosphere at Iglesia de Socaire.

For traveler tips, maps, and tourist information, read our San Pedro de Atacama trip planning tool .

You can do a combination of shuttle and flight from Valparaiso to San Pedro de Atacama in 6.5 hours. Alternatively, you can do a combination of shuttle, flight, and bus; or drive. Traveling from Valparaiso in October, you will find days in San Pedro de Atacama are a bit warmer (28°C), and nights are a bit cooler (3°C). Finish your sightseeing early on the 26th (Sat) to allow enough time to travel back home.

Things to do in San Pedro de Atacama

Parks Nature Outdoors

Side Trip

Cementerio de Toconao
Highlights from your plan
Piedras Rojas ©
Piedras Rojas
Lascar ©
Lascar
Valle Arcoiris ©
Valle Arcoiris

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