22 days in Sicily Itinerary

22 days in Sicily Itinerary

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Route & dates

22 days in Sicily Itinerary

Start: Madrid
Fly:  6​h 30​min
1
Lampedusa
— 3 nights
+3
Fly + Bus + Foot + Train:  3​h 45​min
2
Syracuse
— 5 nights
Drive:  2​h 45​min
3
Agrigento
— 2 nights
Bus:  2​h
4
Palermo
— 5 nights
Drive:  3​h 15​min
5
Isola di Favignana
— 3 nights
Drive:  2​h 30​min
6
San Vito lo Capo
— 3 nights
Taxi + Fly:  4​h 45​min
End: Madrid

3
nights
Lampedusa

Lampedusa ©
Italy's southernmost territory, Lampedusa, is known for its turquoise waters, white-sand beaches, and island charm.
Lampedusa is known for beaches, wildlife, and nightlife. Your plan includes some of its best attractions: enjoy the sand and surf at Spiaggia dei Conigli, identify plant and animal life at Centro di Recupero Tartarughe e Fauna Selvatica WWF, stroll through Cala Croce Beach, and hit the best photo ops around with an inspiring photography tour.

For topicsMoreInfo.option.ratings, other places to visit, maps, and more tourist information, go to the Lampedusa online trip itinerary builder .

Madrid, Spain to Lampedusa is an approximately 6.5-hour flight. You can also do a combination of train, bus, and ferry; or do a combination of bus and ferry. Traveling from Madrid in July, you will find days in Lampedusa are little chillier (32°C), and nights are somewhat warmer (27°C). Finish up your sightseeing early on the 13th (Mon) so you can travel to Syracuse.

Things to do in Lampedusa

Outdoors Parks Beaches
Highlights from your plan
Spiaggia dei Conigli ©
Spiaggia dei Conigli
La Tabaccara ©
La Tabaccara
Cala Pulcino ©
Cala Pulcino

5
nights
Syracuse

Syracuse ©
Philosopher Cicero once described Syracuse as "the greatest Greek city and the most beautiful of them all." A powerful city-state of ancient Greece, Syracuse now is the capital of the eponymous Italian province on the eastern coast of Sicily.
Get out of town with these interesting Syracuse side-trips: Scicli (Gli Aromi Sicily, A Rutta ri Ron Carmelu, &more), Ragusa Ibla (in Ragusa) and Modica (EDR Lab, Chiesa di Santa Maria di Betlem, &more). Next up on the itinerary: step off the mainland to explore Ortigia, delve into the distant past at Parco Archeologico della Neapolis, kick back and relax at Spiaggia Calamosche, and explore the fascinating underground world of Ear of Dionysius (Orecchio di Dionisio).

To find topicsMoreInfo.option.ratings, other places to visit, maps, and more tourist information, refer to the Syracuse trip itinerary planning site .

You can do a combination of flight and train from Lampedusa to Syracuse in 4 hours. Alternatively, you can do a combination of ferry and car; or do a combination of ferry and bus. Finish up your sightseeing early on the 18th (Sat) so you can go by car to Agrigento.

Things to do in Syracuse

Historic Sites Parks Nature

Side Trips

Scicli, Modica, Noto, Ragusa Ibla, Cavagrande del Cassibile
Highlights from your plan
Ortigia ©
Ortigia
Duomo di Siracusa ©
Duomo di Siracusa
Centro Storico ©
Centro Storico

2
nights
Agrigento

Agrigento ©
Historically one of ancient Greece's leading cities, Sicily's Agrigento is home to the seven monumental temples that make up the well-preserved Valley of the Temples.
On the 19th (Sun), explore the striking landscape at Scala dei Turchi, then take in nature's colorful creations at Il Giardino della Kolymbethra, and then delve into the distant past at Valle dei Templi. Here are some ideas for day two: take an in-depth tour of Museo Archeologico Regionale di Agrigento, then kick back and relax at Spiaggia at Siculiana Marittima, then look for all kinds of wild species at Riserva Naturale Orientata Torre Salsa, and finally see the interesting displays at Mulino Dell'acqua - Museo Civico Di Cianciana.

To find reviews, more things to do, where to stay, and other tourist information, read our Agrigento vacation maker tool .

Traveling by car from Syracuse to Agrigento takes 3 hours. Alternatively, you can do a combination of train and bus; or take a bus. In July, daytime highs in Agrigento are 32°C, while nighttime lows are 26°C. Finish up your sightseeing early on the 20th (Mon) so you can catch the bus to Palermo.

Things to do in Agrigento

Parks Historic Sites Nature

Side Trips

Riserva Naturale Orientata Torre Salsa, Mulino Dell'acqua - Museo Civico Di Cianciana, Spiaggia at Siculiana Marittima, Scala dei Turchi
Highlights from your plan
Valle dei Templi ©
Valle dei Templi
Scala dei Turchi ©
Scala dei Turchi
Riserva Naturale Orientata Torre Salsa ©

5
nights
Palermo

Palermo ©
The capital of Sicily, Palermo was founded by the Phoenicians under the name of Ziz.
Explore Palermo's surroundings by going to Museo dell'Acciuga (in Aspra), Azienda Agricola Montalbano (in Menfi) and Duomo di Monreale (in Monreale). The adventure continues: take in the architecture and atmosphere at Cattedrale di Palermo, see the interesting displays at Museo del Giocattolo Sciacca, take a stroll through Cefalu Coast, and admire the striking features of Palazzo Conte Federico.

To find more things to do and more tourist information, read Palermo planning tool .

Traveling by bus from Agrigento to Palermo takes 2 hours. Alternatively, you can drive; or take a train. Wrap up your sightseeing on the 25th (Sat) to allow time to drive to Isola di Favignana.

Things to do in Palermo

Historic Sites Museums Parks

Side Trips

Cefalu, Duomo di Monreale, Museo del Giocattolo Sciacca, Azienda Agricola Montalbano, Museo dell'Acciuga
Highlights from your plan
Cattedrale di Palermo ©
Cattedrale di Palermo
Norman Palace ©
Norman Palace
Duomo di Monreale ©
Duomo di Monreale

3
nights
Isola di Favignana

Isola di Favignana ©
Once famous for its white tuff shell quarries and tuna can factory--now turned into a museum--Isola di Favignana attracts divers and beachgoers with its jagged coastline rich in coves and caves.
Isola di Favignana is known for museums, beaches, and wildlife. Your plan includes some of its best attractions: enjoy the sand and surf at Spiaggia di Cala Rossa, explore the activities along Egadi Sea, contemplate the long history of Ex Stabilimento Florio delle Tonnare di Favignana e Formica, and cool off at Lido Burrone.

To see topicsMoreInfo.option.ratings, other places to visit, where to stay, and tourist information, read Isola di Favignana trip maker website .

You can drive from Palermo to Isola di Favignana in 3.5 hours. Expect a daytime high around 35°C in July, and nighttime lows around 23°C. Cap off your sightseeing on the 28th (Tue) early enough to go by car to San Vito lo Capo.

Things to do in Isola di Favignana

Outdoors Tours Wildlife
Highlights from your plan
Spiaggia di Cala Rossa ©
Spiaggia di Cala Rossa
Grotte bue marino ©
Grotte bue marino

3
nights
San Vito lo Capo

A vacation in San Vito lo Capo offers a chance to enjoy a sheltered bay and a town with distinctive Arab-Norman architecture.
Explore San Vito lo Capo's surroundings by going to Tempio di Segesta (in Calatafimi-Segesta), Castello di Venere (in Erice) and Museum Of Optical Illusions (in Trapani). There's lots more to do: kick back and relax at Spiaggia di San Vito lo Capo, get interesting insight from Tours, contemplate in the serene atmosphere at Santuario Di San Vito, and tour the pleasant surroundings at Spiaggia di Macari.

For reviews, where to stay, more things to do, and other tourist information, refer to the San Vito lo Capo journey planning app .

Getting from Isola di Favignana to San Vito lo Capo by car takes about 2.5 hours. July in San Vito lo Capo sees daily highs of 34°C and lows of 26°C at night. Finish your sightseeing early on the 31st (Fri) to allow enough time to travel back home.

Things to do in San Vito lo Capo

Outdoors Beaches Parks

Side Trips

Castello di Venere, Museum Of Optical Illusions, Tempio di Segesta
Highlights from your plan
Scuba & Snorkeling
Spiaggia di San Vito lo Capo ©
Spiaggia di San Vito lo Capo
Tempio di Segesta ©
Tempio di Segesta

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