22 days in Italy Itinerary

22 days in Italy Itinerary

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Route & dates

22 days in Italy Itinerary

Start: Cape Town
Fly:  17​h 15​min
1
Rome
— 3 nights
Train:  1​h 45​min
2
Salerno
— 2 nights
Ferry:  1​h 30​min
3
Positano
— 3 nights
Drive:  4​h 45​min
4
Assisi
— 2 nights
Drive:  2​h 15​min
5
Florence
— 2 nights
Train:  1​h 45​min
6
Milan
— 1 night
Train:  1​h 15​min
7
Verona
— 2 nights
Bus:  1​h 30​min
8
Venice
— 3 nights
Fly:  3​h 15​min
9
Rome
— 1 night
Fly:  17​h 15​min
End: Cape Town

3
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
Step off the beaten path and head to Monastero Di S.Benedetto and Piazza del Campidoglio. And it doesn't end there: contemplate the long history of Colle Aventino, admire the masterpieces at National Gallery of Ancient Art in Barberini Palace, see the interesting displays at Complesso del Vittoriano, and take in the architecture and atmosphere at Basilica di Santa Prassede.

For ratings, where to stay, traveler tips, and more tourist information, use the Rome online trip planner .

Cape Town, South Africa to Rome is an approximately 17.5-hour combination of bus and flight. You can also do a combination of bus, flight, and train. The time zone changes from South Africa Standard Time (SAST) to Central European Time (CET), which is usually a -1 hour difference. Expect somewhat warmer temperatures when traveling from Cape Town in September; daily highs in Rome reach 32°C and lows reach 18°C. Wrap up your sightseeing on the 10th (Thu) to allow time to take a train to Salerno.

Things to do in Rome

Historic Sites Museums Parks

Side Trip

Monastero Di S.Benedetto
Highlights from your plan
Welcome to Rome ©
Welcome to Rome
Foro di Cesare ©
Foro di Cesare
Piazza del Campidoglio ©
Piazza del Campidoglio

2
nights
Salerno

Salerno ©
While often overshadowed by the Amalfi Coast's array of quaint villages, Salerno has become one of the region's main areas for culture and entertainment, while remaining relatively unmarked by tourism.
Kick off your visit on the 11th (Fri): head outdoors with Cilento, then make a trip to Chiesa San Pietro a Corte, then look for gifts at Lavorazione Artigianale Savastano, and finally get engrossed in the history at Museo Archeologico Provinciale di Salerno. Get ready for a full day of sightseeing on the 12th (Sat): test your team's savvy at Escape Room Intrappola.TO - Salerno, don't miss a visit to Chiesa di San Giorgio, then examine the collection at Pinacoteca Provinciale Salerno, and finally see the interesting displays at Museo Diocesano San Matteo di Salerno.

For traveler tips, where to stay, other places to visit, and other tourist information, go to the Salerno trip planner .

Traveling by train from Rome to Salerno takes 2 hours. Alternatively, you can drive; or take a bus. Traveling from Rome in September, expect a bit warmer with lows of 24°C in Salerno. Finish your sightseeing early on the 12th (Sat) so you can ride a ferry to Positano.

Things to do in Salerno

Museums Outdoors Fun & Games
Highlights from your plan
Cilento ©
Cilento
Chiesa San Pietro a Corte ©
Chiesa San Pietro a Corte

3
nights
Positano

Positano ©
Often referred to as the gem of the Amalfi Coast, Positano remains one of southern Italy's most sought-after vacation locales, thanks to its hillside location and picturesque, pastel buildings.
Positano is known for beaches, shopping, nature, nightlife, and classes. Your plan includes some of its best attractions: take your sightseeing to a higher altitude at Monte Faito e Panorama, pause for some serene contemplation at Cloister del Paradiso, add some adventure to your tour with a kayaking and canoeing tour, and make a trip to Parrocchia Di San Gennaro.

For other places to visit, traveler tips, ratings, and more tourist information, read our Positano trip itinerary builder site .

You can ride a ferry from Salerno to Positano in 1.5 hours. Other options are to do a combination of train and taxi; or drive. Expect a daytime high around 31°C in September, and nighttime lows around 23°C. Finish up your sightseeing early on the 15th (Tue) so you can go by car to Assisi.

Things to do in Positano

Outdoors Parks Historic Sites

Side Trips

Amalfi, Parrocchia Di San Gennaro, Monte Faito e Panorama
Highlights from your plan
Walk of the Gods ©
Walk of the Gods
Church of Santa Maria Assunta ©
Church of Santa Maria Assunta
Parrocchia Di San Gennaro ©
Parrocchia Di San Gennaro

2
nights
Assisi

Assisi ©
Rich in culture and religious tradition, Assisi is known as the birthplace of St.
Kick off your visit on the 16th (Wed): take in the architecture and atmosphere at St. Peter's Abbey, then don't miss a visit to Piazza Inferiore di San Francesco, then get to know the fascinating history of Centro Storico, and finally take in the exciting artwork at Assisi Galleria 6C. Keep things going the next day: admire the masterpieces at Museo Diocesano e Cripta di San Rufino, stop by Sapori dall'Umbria, admire the landmark architecture of Palazzo Bonacquisti, then take in panoramic vistas at Torre del Popolo, then don't miss a visit to Oratorio S. Francesco Piccolino, and finally appreciate the extensive heritage of Piazza Superiore di San Francesco.

To find traveler tips, reviews, ratings, and more tourist information, read Assisi itinerary planner.

Getting from Positano to Assisi by car takes about 5 hours. Other options: do a combination of subway and train; or take a bus. Expect a bit cooler evenings in Assisi when traveling from Positano in September, with lows around 16°C. Cap off your sightseeing on the 17th (Thu) early enough to go by car to Florence.

Things to do in Assisi

Historic Sites Museums Shopping
Highlights from your plan
Azienda Agraria Saio ©
Azienda Agraria Saio
Sapori dall'Umbria ©
Sapori dall'Umbria
Centro Storico di Assisi ©
Centro Storico di Assisi

2
nights
Florence

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Kick off your visit on the 18th (Fri): take in the spiritual surroundings of Church and Museum of Orsanmichele, get engrossed in the history at Corridoio Vasariano, test your problem-solving skills at popular escape rooms, then browse the exhibits of Museo degli Innocenti, and finally pause for some photo ops at Loggia dei Lanzi. On the 19th (Sat), you'll have a packed day of sightseeing: contemplate in the serene atmosphere at Chiesa di Santa Maria del Carmine, admire the local landmark of Fountain of Neptune, then see the interesting displays at Museo di Palazzo Davanzati, and finally admire the masterpieces at Palazzo Strozzi.

For ratings, other places to visit, reviews, and more tourist information, refer to the Florence online travel planner .

Traveling by car from Assisi to Florence takes 2.5 hours. Alternatively, you can take a train. In September, plan for daily highs up to 30°C, and evening lows to 17°C. Cap off your sightseeing on the 19th (Sat) early enough to catch the train to Milan.

Things to do in Florence

Museums Historic Sites Fun & Games
Highlights from your plan
Church and Museum of Orsanmichele ©
Church and Museum of Orsanmichele
Corridoio Vasariano ©
Corridoio Vasariano
Fountain of Neptune ©
Fountain of Neptune

1
night
Milan

Milan ©
In many ways the most modern of Italian cities, Milan is a busy, elegant metropolis with an impressive list of grand palaces, fine churches, and important museums.
On the 20th (Sun), admire the striking features of Casa Degli Atellani - La Vigna Di Leonardo, get a sense of history and politics at Palazzo Marino, then don't miss a visit to Piazza Mercanti, and finally appreciate the history behind Monumento a Vittorio Emanuele II.

To see other places to visit, ratings, where to stay, and more tourist information, refer to the Milan holiday planner.

You can take a train from Florence to Milan in 2 hours. Other options are to drive; or fly. In September in Milan, expect temperatures between 28°C during the day and 16°C at night. Finish your sightseeing early on the 20th (Sun) so you can take a train to Verona.

Things to do in Milan

Historic Sites Parks Museums
Highlights from your plan
Palazzo Marino ©
Palazzo Marino
Piazza Mercanti ©
Piazza Mercanti

2
nights
Verona

Verona ©
The famous setting for Shakespeare's star-crossed lovers, Romeo and Juliet, Verona is one of northern Italy's main tourist destinations, largely owing to its incredibly rich artistic heritage.
On the 21st (Mon), pause for some photo ops at Porta dei Leoni, make a trip to Santuario Madonna di Lourdes, then let your taste buds guide you at a local gastronomic tour, then admire the landmark architecture of Case Mazzanti, and finally take in the architecture and atmosphere at Santa Maria Antica. On the next day, get engrossed in the history at Museo Archeologico al Teatro Romano, don't miss a visit to Funicolare di Castel San Pietro, then admire the landmark architecture of Palazzo dei Tribunali, then appreciate the history behind La Loggia del Consiglio, and finally make a trip to Palazzo della Ragione.

Plan trip to Verona with our itinerary maker to find out where to go and what to do.

Traveling by train from Milan to Verona takes 1.5 hours. Alternatively, you can drive. In September, plan for daily highs up to 30°C, and evening lows to 17°C. Wrap up your sightseeing on the 22nd (Tue) to allow time to take a bus to Venice.

Things to do in Verona

Historic Sites Museums
Highlights from your plan
Santa Maria Antica ©
Santa Maria Antica
Funicolare di Castel San Pietro ©
Funicolare di Castel San Pietro
Palazzo della Ragione ©
Palazzo della Ragione

3
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Discover out-of-the-way places like Santuario della Madonna dell'Angelo and No Exit. Step out of Venice with an excursion to PDC Cartizze in Valdobbiadene--about 1h 15 min away. And it doesn't end there: wander the streets of Cannaregio, step off the mainland to explore Giudecca, don't miss a visit to Campo Santa Margherita, and admire the masterpieces at Ca' Pesaro Galleria Internazionale d'Arte Moderna.

For more things to do, reviews, other places to visit, and more tourist information, you can read our Venice trip maker site .

You can take a bus from Verona to Venice in 1.5 hours. Alternatively, you can drive; or take a shuttle. In September, daytime highs in Venice are 29°C, while nighttime lows are 17°C. Wrap up your sightseeing on the 25th (Fri) early enough to travel to Rome.

Things to do in Venice

Museums Fun & Games Nature

Side Trips

Santuario della Madonna dell'Angelo, PDC Cartizze, No Exit
Highlights from your plan
PDC Cartizze ©
PDC Cartizze
Santuario della Madonna dell'Angelo ©
Giudecca ©
Giudecca

1
night
Rome

Rome ©
Kick off your visit on the 26th (Sat): delve into the distant past at Domus Aurea, then don't miss a visit to Monte Palatino, then take in the spiritual surroundings of Tempio Di Ercole Vincitore, and finally take in nature's colorful creations at Vatican Gardens.

Planning Rome trip won't be overwheling when you use's Insprock itinerary maker.

Fly from Venice to Rome in 3.5 hours. Alternatively, you can take a train; or drive. Finish your sightseeing early on the 26th (Sat) to allow enough time to travel back home.

Things to do in Rome

Historic Sites Parks

Side Trip

Vatican Gardens
Highlights from your plan
Domus Aurea ©
Domus Aurea
Vatican Gardens ©
Vatican Gardens
Tempio Di Ercole Vincitore ©
Tempio Di Ercole Vincitore

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