21 days in Spain Itinerary

21 days in Spain Itinerary

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Route & dates

21 days in Spain Itinerary

Start: Amsterdam
Fly:  2​h 30​min
1
Madrid
— 3 nights
Train:  45​min
2
Toledo
— 1 night
Drive:  1​h 45​min
3
Avila
— 1 night
bus:  1​h 30​min
4
San Lorenzo de El Escorial
— 1 day
Bus:  1​h 30​min
5
Segovia
— 1 night
Drive:  1​h
6
Avila
— 2 nights
Drive:  1​h 15​min
7
Salamanca
— 1 night
Drive:  3​h 15​min
8
Aranda de Duero
— 1 day
Drive:  2​h 30​min
9
Avila
— 1 night
Train + Fly:  5​h 15​min
10
Granada
— 1 night
Drive:  2​h 15​min
11
Cordoba
— 2 nights
Train:  45​min
12
Seville
— 4 nights
Fly:  3​h 30​min
13
Barcelona
— 3 nights
Fly:  5​h
End: Amsterdam

3
nights
Madrid

Madrid ©
Madrid is known for its cultural and artistic heritage, lively nightlife, and a dynamic culinary scene.
Deepen your sense of the past at sights like Royal Palace of Madrid and Casa de Campo. Satisfy your inner culture vulture at Prado National Museum and Thyssen-Bornemisza Museum (Museo Thyssen-Bornemisza). The adventure continues: admire the masterpieces at Museo Nacional Centro de Arte Reina Sofia, tour the pleasant surroundings at Retiro Park (Parque del Retiro), shop like a local with Gran Via, and take in the spiritual surroundings of Real Basilica de San Francisco el Grande.

To find photos, reviews, traveler tips, and other tourist information, read our Madrid trip itinerary builder app .

Amsterdam, The Netherlands to Madrid is an approximately 5.5-hour flight. You can also do a combination of train and flight; or drive. Expect somewhat warmer temperatures when traveling from Amsterdam in October; daily highs in Madrid reach 26°C and lows reach 13°C. Finish your sightseeing early on the 24th (Wed) to allow enough time to take a train to Toledo.

Things to do in Madrid

Historic Sites Neighborhoods Museums
Highlights from your plan
Prado National Museum ©
Prado National Museum
Royal Palace of Madrid ©
Royal Palace of Madrid
Plaza Mayor ©
Plaza Mayor

1
night
Toledo

Toledo ©
Toledo is a World Heritage Site that embodies the complex cultural history of Spain while remaining a forward-moving, modern city.
You've added Puerta del Sol, Puerta de Bisagra, Mirador del Valle, and other attractions to your itinerary. On the 24th (Wed), don't miss a visit to Mirador del Valle.

For photos, where to stay, more things to do, and more tourist information, go to the Toledo itinerary maker .

Take a train from Madrid to Toledo in an hour. Alternatively, you can drive; or take a bus. October in Toledo sees daily highs of 26°C and lows of 13°C at night. Wrap up your sightseeing on the 25th (Thu) early enough to drive to Avila.

Things to do in Toledo

Historic Sites Museums
Highlights from your plan
Catedral Primada ©
Catedral Primada
Museo del Greco ©
Museo del Greco

1
night
Avila

Avila
To see photos, other places to visit, reviews, and tourist information, read our Avila trip maker website .

Getting from Toledo to Avila by car takes about 2 hours. Other options: take a bus; or take a train. Plan for slightly colder nights when traveling from Toledo in October since evenings lows in Avila dip to 7°C. You will have some time to spend on the 26th (Fri) before leaving for San Lorenzo de El Escorial.

Things to do in Avila

Historic Sites

1
day
San Lorenzo de El Escorial

San Lorenzo de El Escorial
San Lorenzo de El Escorial, also known as El Escorial de Arriba is a town and municipality in the Community of Madrid, Spain, located to the northwest of the region in the southeastern side of the Sierra de Guadarrama, at the foot of Mount Abantos and Las Machotas, 29mi from Madrid. For traveler tips, reviews, maps, and tourist information, read our San Lorenzo de El Escorial trip builder app .

You can drive from Avila to San Lorenzo de El Escorial in an hour. Another option is to take a train. On the 26th (Fri), you're off toSegovia.

Things to do in San Lorenzo de El Escorial

Outdoors Historic Sites Parks

1
night
Segovia

Segovia
As one of Spain’s most well-preserved medieval cities, Segovia is known for its 1st-century Roman aqueduct that runs through the city center.
For photos and tourist information, read our Segovia trip itinerary planner.

Getting from San Lorenzo de El Escorial to Segovia by car takes about an hour. Other options: take a train; or take a bus. Expect a daytime high around 23°C in October, and nighttime lows around 14°C. On the 27th (Sat), you'll travel to Avila.

Things to do in Segovia

Historic Sites Outdoors Tours

2
nights
Avila

Avila ©
To see reviews, other places to visit, photos, and other tourist information, use the Avila trip planner.

Getting from San Lorenzo de El Escorial to Avila by car takes about an hour. Other options: take a train. Wrap up your sightseeing on the 28th (Sun) early enough to drive to Salamanca.

Things to do in Avila

Historic Sites Shopping Museums
Highlights from your plan
Cathedral of Avila ©
Cathedral of Avila
Parish of St. Peter the Apostle ©
Parish of St. Peter the Apostle
Real Monasterio de Santo Tomas ©
Real Monasterio de Santo Tomas

1
night
Salamanca

Salamanca ©
Salamanca is one of the most visited cities in Spain.
To find reviews, traveler tips, maps, and other tourist information, you can read our Salamanca online trip itinerary planner .

Traveling by car from Avila to Salamanca takes 1.5 hours. Alternatively, you can take a train; or take a bus. In October, daytime highs in Salamanca are 25°C, while nighttime lows are 7°C. Finish up your sightseeing early on the 30th (Tue) so you can travel to Aranda de Duero.

Things to do in Salamanca

Historic Sites Museums
Highlights from your plan
New Cathedral (Catedral Nueva) ©
New Cathedral (Catedral Nueva)

1
day
Aranda de Duero

Aranda de Duero ©
Aranda de Duero is a town and municipality, capital of the Ribera del Duero comarca, in south of the province of Burgos, in Castile and León, Spain. Kick off your visit on the 30th (Tue): do a tasting at Don Carlos Bodega Historica, take in the architecture and atmosphere at Iglesia de Santa Maria, get engrossed in the history at Museo Sacro Iglesia de San Juan, then pause for some photo ops at Plaza Mayor, and finally steep yourself in history at Monasterio de Santa Maria de La Vid.

To find maps, other places to visit, traveler tips, and more tourist information, go to the Aranda de Duero day trip tool .

Drive from Salamanca to Aranda de Duero in 2.5 hours. When traveling from Salamanca in October, plan for a bit cooler days and about the same nights in Aranda de Duero: temperatures range from 20°C by day to 8°C at night. Finish up your sightseeing early on the 30th (Tue) so you can travel to Avila.

Things to do in Aranda de Duero

Historic Sites Wineries Museums

Side Trips

Plaza Mayor de Penaranda de Duero, Monasterio de Santa Maria de La Vid
Highlights from your plan
Museo Sacro Iglesia de San Juan ©
Museo Sacro Iglesia de San Juan
Monasterio de Santa Maria de La Vid ©
Iglesia de Santa Maria ©
Iglesia de Santa Maria

1
night
Avila

Avila ©
To find other places to visit, reviews, traveler tips, and tourist information, refer to the Avila attractions planner .

You can drive from Aranda de Duero to Avila in 2.5 hours. When traveling from Aranda de Duero in October, plan for somewhat warmer days and about the same nights in Avila: temperatures range from 24°C by day to 7°C at night. Finish your sightseeing early on the 31st (Wed) to allow enough time to drive to Granada.

Things to do in Avila

Historic Sites Museums
Highlights from your plan
Museo del Convento de la Encarnacion ©

1
night
Granada

Granada ©
Granada boasts numerous well-preserved examples of exquisite Moorish architecture, not the least of which is the Alhambra, an ancient citadel and royal palace.
Start off your visit on the 31st (Wed): look and learn at Science Park (Parque de las Ciencias), admire the masterpieces at Museum of Fine Arts, Granada, admire the striking features of Alhambra, then steep yourself in history at Casa-Museo de Manuel de Falla, then examine the collection at Casa Museo Max Moreau, and finally steep yourself in history at Mirador de San Nicolas. Keep things going the next day: pause for some serene contemplation at Iglesia de San Miguel Bajo, contemplate the long history of Generalife, shop like a local with Galeria Alea, then explore the world behind art at Monasterio de la Concepcion, then examine the collection at Palacio de los Olvidados, and finally explore the galleries of Archive Saint John of God Museum.

To find reviews, where to stay, maps, and tourist information, refer to the Granada trip planning app .

Getting from Avila to Granada by car takes about 5.5 hours. Other options: do a combination of train and flight; or take a bus. Expect a bit warmer temperatures when traveling from Avila in October; daily highs in Granada reach 28°C and lows reach 14°C. Cap off your sightseeing on the 1st (Thu) early enough to go by car to Cordoba.

Things to do in Granada

Museums Historic Sites Childrens Museums
Highlights from your plan
Alhambra ©
Alhambra
Albayzin ©
Albayzin
Mirador de San Nicolas ©
Mirador de San Nicolas

2
nights
Cordoba

Cordoba ©
Andalucía’s thousand-year-old city, Córdoba, was once the capital of both the Roman Empire and the Moorish Kingdom, representing an alluring mix of cultural and political history.
Kick off your visit on the 1st (Thu): make a trip to Patios de Cordoba and then take in the views from Roman Bridge.

For reviews, photos, other places to visit, and tourist information, refer to the Cordoba road trip planner.

You can drive from Granada to Cordoba in 2.5 hours. Alternatively, you can take a train; or take a bus. Expect a bit warmer weather when traveling from Granada in November: highs in Cordoba hover around 23°C, while lows dip to 8°C. Wrap up your sightseeing on the 3rd (Sat) early enough to take a train to Seville.

Things to do in Cordoba

Historic Sites Museums Neighborhoods
Highlights from your plan
Mezquita Cathedral de Cordoba ©
Mezquita Cathedral de Cordoba
Jewish Quarter (Juderia) ©
Jewish Quarter (Juderia)
Alcazar de los Reyes Cristianos ©
Alcazar de los Reyes Cristianos

4
nights
Seville

Seville ©
A city of rich Moorish heritage, Seville is the cultural and financial center of southern Spain, and the site of numerous festivals throughout the year.
Your cultural itinerary includes sights like Royal Alcázar of Seville and Barrio Santa Cruz. Let the collections at Museum of Fine Arts, Sevilla and Torre del Oro capture your imagination. Change things up with these side-trips from Seville: Ronda (Plaza de Toros, Puente Nuevo, & more). Next up on the itinerary: take some stellar pictures from Seville Cathedral, take in nature's colorful creations at Casa de Pilatos, contemplate in the serene atmosphere at Basilica de la Macarena, and pause for some serene contemplation at Iglesia Colegial del Salvador.

For ratings, maps, photos, and tourist information, use the Seville online trip maker .

Take a train from Cordoba to Seville in an hour. Alternatively, you can drive; or take a bus. In November in Seville, expect temperatures between 22°C during the day and 11°C at night. Finish your sightseeing early on the 7th (Wed) to allow enough time to travel to Barcelona.

Things to do in Seville

Historic Sites Neighborhoods Parks

Side Trip

Ronda
Highlights from your plan
Plaza de España ©
Plaza de España
Royal Alcázar of Seville ©
Royal Alcázar of Seville
Catedral de Sevilla ©
Catedral de Sevilla

3
nights
Barcelona

Barcelona ©
Barcelona, the country’s second-largest city, is a cosmopolitan urban center known for its throbbing youthful energy and stellar architecture.
Deepen your sense of the past at sights like El Barri Gòtic and Casa Batllo. Basilica of the Sagrada Familia and Barcelona Cathedral are good opportunities to explore the local culture. There's lots more to do: pause for some photo ops at Casa Mila - La Pedrera, don't miss a visit to Las Ramblas, examine the collection at Parc de Montjuic, and admire the striking features of Palau Guell.

To see more things to do, where to stay, traveler tips, and other tourist information, read our Barcelona road trip app .

Traveling by flight from Seville to Barcelona takes 3.5 hours. Alternatively, you can take a train; or drive. In November, daytime highs in Barcelona are 21°C, while nighttime lows are 11°C. You'll have a few hours on the 10th (Sat) to wrap things up before traveling home.

Things to do in Barcelona

Historic Sites Neighborhoods Museums
Highlights from your plan
El Barri Gòtic ©
El Barri Gòtic
Basilica of the Sagrada Familia ©
Basilica of the Sagrada Familia
Las Ramblas ©
Las Ramblas

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