21 days in South America Itinerary

21 days in South America Itinerary

Created using Inspirock South America itinerary builder

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Route & dates

21 days in South America Itinerary

Start: Seattle, United States
Fly:  22​h 30​min
1
Fernando de Noronha, Brazil
— 3 nights
Fly:  7​h 45​min
2
Rio de Janeiro, Brazil
— 2 nights
Fly:  2​h 30​min
3
Foz do Iguacu, Brazil
— 2 nights
Drive:  45​min
4
Iguazu National Park, Argentina
— 1 night
Fly:  3​h 30​min
5
Buenos Aires, Argentina
— 3 nights
Fly:  6​h 30​min
6
Los Glaciares National Park, Argentina
— 1 night
+2
shuttle + taxi + Fly:  8​h 30​min
7
Santiago, Chile
— 2 nights
Fly:  6​h 15​min
8
Cusco, Peru
— 2 nights
+2
bus + foot + train:  3​h 15​min
9
Machu Picchu, Peru
— 1 night
Drive + Fly:  27​h
End: Seattle, United States

3
nights
Fernando de Noronha, Brazil

Fernando de Noronha ©
With 21 lush islands scattered among pristine waters in the Atlantic Ocean, a Fernando de Noronha holiday is well worth the effort it takes to get there.
Fernando de Noronha is known for beaches, museums, wildlife, outdoors, and nature. Your plan includes some of its best attractions: tour the pleasant surroundings at Baia do Sancho, enjoy the sand and surf at Fernando de Noronha, head outdoors with Baia dos Porcos, and go for a walk through Trilha Atalaia.

To see where to stay, more things to do, traveler tips, and tourist information, read our Fernando de Noronha trip app .

Seattle, USA to Fernando de Noronha is an approximately 22.5-hour flight. You can also do a combination of shuttle and flight. Traveling from Seattle to Fernando de Noronha, you'll lose 6 hours due to the time zone difference. Expect somewhat warmer temperatures when traveling from Seattle in September; daily highs in Fernando de Noronha reach 84°F and lows reach 76°F. Cap off your sightseeing on the 12th (Thu) early enough to travel to Rio de Janeiro.

Things to do in Fernando de Noronha

Outdoors Parks Beaches
Highlights from your plan
Baia do Sancho ©
Baia do Sancho
Baia dos Porcos ©
Baia dos Porcos
Praia do Sueste ©
Praia do Sueste

2
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
On the 13th (Fri), pause for some photo ops at Corcovado Christ the Redeemer, then kick back and relax at Copacabana Beach, then get great views at Pao de Acucar, and finally don't miss a visit to Escadaria Selaron. Keep things going the next day: kick back and relax at Barra da Tijuca Beach, then take in nature's colorful creations at Jardim Botânico do Rio de Janeiro, then enjoy the sand and surf at Praia de Ipanema, and finally enjoy the sand and surf at Pedra do Arpoador.

Before you visit Rio de Janeiro, use our trip planner to discover what you can do and see there.

Fly from Fernando de Noronha to Rio de Janeiro in 8 hours. The time zone difference moving from Fernando de Noronha Time (FNT) to Brasilia Time (BRT) is minus 1 hour. Traveling from Fernando de Noronha in September, you can expect nighttime temperatures to be a bit cooler in Rio de Janeiro, with lows of 68°F. Finish your sightseeing early on the 14th (Sat) so you can travel to Foz do Iguacu.

Things to do in Rio de Janeiro

Parks Beaches Outdoors
Highlights from your plan
Bondinho  Pao de Acucar ©
Bondinho Pao de Acucar
Corcovado Christ the Redeemer ©
Corcovado Christ the Redeemer
Copacabana Beach ©
Copacabana Beach

2
nights
Foz do Iguacu, Brazil

Foz do Iguacu ©
A gateway to the world-renowned Iguacu Falls, which spectacularly divide Brazil and Argentina, the modern, high-rise city of Foz do Iguacu can't help but play second fiddle to the natural wonder in its vicinity.
Kick off your visit on the 15th (Sun): take in the spiritual surroundings of Buddhist Temple, then get to know the resident critters at Parque das Aves Bird Park, and then admire the engineering at Itaipu Dam. Get ready for a full day of sightseeing on the next day: admire the engineering at Iguazu Falls.

Discover how to plan a Foz do Iguacu trip in just a few steps with Inspirock's itinerary builder.

Fly from Rio de Janeiro to Foz do Iguacu in 2.5 hours. Alternatively, you can drive; or take a bus. Plan for slightly colder nights when traveling from Rio de Janeiro in September since evenings lows in Foz do Iguacu dip to 59°F. Finish up your sightseeing early on the 16th (Mon) so you can go by car to Iguazu National Park.

Things to do in Foz do Iguacu

Parks Nature Zoos & Aquariums
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Parque das Aves Bird Park ©
Parque das Aves Bird Park
Itaipu Dam ©
Itaipu Dam

1
night
Iguazu National Park, Argentina

Iguazu National Park ©
Iguazu National Park contains 672 sq km (259 sq mi) of fertile subtropical forests, but its main attraction is the majestic Iguazu Falls.
Start off your visit on the 17th (Tue): admire the sheer force of Salto San Martin and then take in the dramatic scenery at Iguazu Falls.

For maps, reviews, more things to do, and other tourist information, use the Iguazu National Park online tour itinerary planner .

Traveling by car from Foz do Iguacu to Iguazu National Park takes an hour. Alternatively, you can take a bus. Expect a daytime high around 81°F in September, and nighttime lows around 58°F. Wrap up your sightseeing on the 17th (Tue) to allow time to travel to Buenos Aires.

Things to do in Iguazu National Park

Parks Nature
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Salto San Martin ©
Salto San Martin

3
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for nightlife, museums, parks, historic sites, and shopping. Your plan includes some of its best attractions: don't miss a visit to Cemiterio de Recoleta, take in the history at Plaza de Mayo, explore the world behind art at Museo Nacional de Bellas Artes, and admire the natural beauty at Jardin Japones.

To see ratings, reviews, photos, and more tourist information, go to the Buenos Aires trip itinerary planner .

You can fly from Iguazu National Park to Buenos Aires in 3.5 hours. Alternatively, you can drive; or take a bus. Plan for little chillier temperatures traveling from Iguazu National Park in September, with highs in Buenos Aires at 64°F and lows at 53°F. Wrap up your sightseeing on the 20th (Fri) to allow time to travel to Los Glaciares National Park.

Things to do in Buenos Aires

Shopping Neighborhoods Museums
Highlights from your plan
Puerto Madero ©
Puerto Madero
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero

1
night
Los Glaciares National Park, Argentina

Los Glaciares National Park ©
A World Heritage Site, Los Glaciares National Park contains a giant ice cap that feeds 47 vast glaciers.
Start off your visit on the 21st (Sat): take in the dramatic natural features at Glaciar Seco and then take in the dramatic natural features at Perito Moreno Glacier.

To find photos, ratings, reviews, and more tourist information, read our Los Glaciares National Park day trip planning tool .

Traveling by flight from Buenos Aires to Los Glaciares National Park takes 6.5 hours. Alternatively, you can do a combination of train and bus; or take a bus. Expect little chillier temperatures when traveling from Buenos Aires in September; daily highs in Los Glaciares National Park reach 45°F and lows reach 44°F. Wrap up your sightseeing on the 21st (Sat) to allow time to travel to Santiago.

Things to do in Los Glaciares National Park

Parks Nature
Highlights from your plan
Perito Moreno Glacier ©
Perito Moreno Glacier
Glaciar Seco ©
Glaciar Seco

2
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Santiago is known for shopping, museums, parks, nature, and historic sites. Your plan includes some of its best attractions: take in the awesome beauty at San Cristóbal Hill, don't miss a visit to Patio Bellavista, see the interesting displays at La Chascona, and admire the landmark architecture of Metropolitan Cathedral (Catedral Metropolitana).

For photos, reviews, other places to visit, and other tourist information, read our Santiago day trip planner .

Traveling by flight from Los Glaciares National Park to Santiago takes 8.5 hours. Alternatively, you can do a combination of bus and flight; or do a combination of flight and bus. Due to the time zone difference, you'll gain 1 hour traveling from Los Glaciares National Park to Santiago. Finish up your sightseeing early on the 24th (Tue) so you can travel to Cusco.

Things to do in Santiago

Parks Museums Nature
Highlights from your plan
San Cristóbal Hill ©
San Cristóbal Hill
Cerro Santa Lucia ©
Cerro Santa Lucia
Patio Bellavista ©
Patio Bellavista

2
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
On the 25th (Wed), take a memorable excursion with exploor, contemplate the long history of Plaza de Armas, then contemplate the long history of Sacsayhuaman, and finally explore the world behind art at Museo de Arte Precolombino. Get ready for a full day of sightseeing on the next day: admire the striking features of Centro Historico De Cusco, pause for some serene contemplation at Iglesia De Santo Domingo, and then look for gifts at Hilo.

To find photos, maps, ratings, and other tourist information, go to the Cusco holiday tool .

Traveling by flight from Santiago to Cusco takes 6.5 hours. Alternatively, you can drive; or take a bus. The time zone changes from Chile Time to Peru Time, which is usually a -1 hour difference. In September, daily temperatures in Cusco can reach 71°F, while at night they dip to 41°F. Finish your sightseeing early on the 26th (Thu) to allow enough time to travel to Machu Picchu.

Things to do in Cusco

Historic Sites Museums Parks
Highlights from your plan
exploor ©
exploor
Sacsayhuaman ©
Sacsayhuaman
Plaza de Armas ©
Plaza de Armas

1
night
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Start off your visit on the 27th (Fri): explore the ancient world of Santuario Historico de Machu Picchu.

For other places to visit, more things to do, where to stay, and other tourist information, read our Machu Picchu trip itinerary site .

You can do a combination of bus and train from Cusco to Machu Picchu in 3.5 hours. Other options are to take a train; or drive. Finish your sightseeing early on the 27th (Fri) so you can travel back home.

Things to do in Machu Picchu

Historic Sites
Highlights from your plan
Santuario Historico de Machu Picchu ©

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