21 days in Italy Itinerary

21 days in Italy Itinerary

Created using Inspirock Italy trip maker

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Route & dates

21 days in Italy Itinerary

Start: Washington DC
Fly:  15 h 30 min
1
Palermo
— 2 nights
Drive:  1 h 30 min
2
Trapani
— 1 night
Train:  30 min
3
Marsala
— Few hours
Bus:  2 h 15 min
4
Agrigento
— 1 night
Drive:  2 h 15 min
5
Ragusa
— 2 nights
Train:  45 min
6
Scicli
— Few hours
Drive:  1 h
7
Noto
— Few hours
Drive:  45 min
8
Modica
— Few hours
Drive:  1 h 15 min
9
Syracuse
— 2 nights
Drive:  1 h
10
Catania
— 1 night
Fly + Drive:  5 h
11
Porto Santo Stefano
— 1 night
+2
Drive + Fly + Drive:  5 h 45 min
12
Taormina
— Few hours
Drive:  3 h 15 min
13
Monreale
— 1 night
Drive:  2 h 15 min
14
Piazza Armerina
— 1 night
Drive:  2 h 15 min
15
Isnello
— 1 night
Drive:  30 min
16
Cefalu
— 2 nights
Drive:  2 h 15 min
17
Erice
— 3 nights
+3
Fly + Foot + Bus + Train:  23 h 45 min
End: Washington DC

2
nights
Palermo

Palermo ©
The capital of Sicily, Palermo was founded by the Phoenicians under the name of Ziz.
Kick off your visit on the 10th (Thu): admire the striking features of Norman Palace, then stroll the grounds of Catacombe dei Cappuccini, then don't miss a visit to Cattedrale di Palermo, and finally indulge your taste buds at Food & Drink.

To see other places to visit, ratings, reviews, and other tourist information, go to the Palermo trip builder tool .

Washington DC, USA to Palermo is an approximately 15.5-hour flight. You can also do a combination of flight and bus; or do a combination of train and flight. Due to the time zone difference, you'll lose 6 hours traveling from Washington DC to Palermo. Finish up your sightseeing early on the 11th (Fri) so you can go by car to Trapani.

Things to do in Palermo

Tours Historic Sites
Highlights from your plan
Cattedrale di Palermo ©
Cattedrale di Palermo
Norman Palace ©
Norman Palace
Catacombe dei Cappuccini ©
Catacombe dei Cappuccini

1
night
Trapani

Trapani ©
Historically known for its importance in salt production, Trapani has gained recognition as an enticing but affordable vacation locale in Sicily.
On the 11th (Fri), don't miss a visit to Chiesa Anime Sante del Purgatorio and then explore the ancient world of Tempio di Segesta.

For where to stay, reviews, maps, and more tourist information, read our Trapani visit planner .

You can drive from Palermo to Trapani in 1.5 hours. Other options are to take a bus; or take a train. Expect a daytime high around 83°F in September, and nighttime lows around 67°F. Wrap up your sightseeing on the 12th (Sat) to allow time to take a train to Marsala.

Things to do in Trapani

Historic Sites

Side Trip

Tempio di Segesta
Highlights from your plan
Tempio di Segesta ©
Tempio di Segesta
Chiesa Anime Sante del Purgatorio ©
Chiesa Anime Sante del Purgatorio

few
hours
Marsala

Marsala ©
Marsala is an Italian town located in the Province of Trapani in the westernmost part of Sicily. Start off your visit on the 12th (Sat): make a trip to Porta Garibaldi, then do a tasting at Donnafugata, and then relax in the rural setting at Saline Della Laguna.

For maps, reviews, traveler tips, and other tourist information, you can read our Marsala planning website .

Marsala is very close to Trapani. In September in Marsala, expect temperatures between 83°F during the day and 67°F at night. Finish up your sightseeing early on the 12th (Sat) so you can catcht the bus to Agrigento.

Things to do in Marsala

Wineries
Highlights from your plan
Donnafugata ©
Donnafugata
Saline Della Laguna ©
Saline Della Laguna
Porta Garibaldi ©
Porta Garibaldi

1
night
Agrigento

Agrigento ©
Historically one of ancient Greece's leading cities, Sicily's Agrigento is home to the seven monumental temples that make up the well-preserved Valley of the Temples.
For photos, ratings, reviews, and other tourist information, refer to the Agrigento trip planner .

Traveling by bus from Marsala to Agrigento takes 2.5 hours. Alternatively, you can drive; or take a train. September in Agrigento sees daily highs of 80°F and lows of 71°F at night. Wrap up your sightseeing on the 13th (Sun) to allow time to drive to Ragusa.

Things to do in Agrigento

Historic Sites Museums
Highlights from your plan
Valle dei Templi ©
Valle dei Templi

2
nights
Ragusa

Ragusa ©
Once a flourishing ancient city, Ragusa was rebuilt after a devastating earthquake in 1693.
On the 14th (Mon), you'll have a packed day of sightseeing: don't miss a visit to Lungomare Andrea Doria e Bisani, appreciate the extensive heritage of Ragusa Ibla, make a trip to Siculamente, then don't miss a visit to teatro dei Donnafugata, and finally take in nature's colorful creations at Giardini Iblei.

Start your trip to Ragusa by creating a personalized itinerary on Inspirock.

You can drive from Agrigento to Ragusa in 2.5 hours. Alternatively, you can do a combination of bus and train; or take a bus. Traveling from Agrigento in September, expect a bit cooler with lows of 63°F in Ragusa. On the 15th (Tue), wrap the sightseeing up by early afternoon so you can take a train to Scicli.

Things to do in Ragusa

Historic Sites Parks
Highlights from your plan
Ragusa Ibla ©
Ragusa Ibla
Duomo San Giorgio ©
Duomo San Giorgio
Giardini Iblei ©
Giardini Iblei

few
hours
Scicli

Scicli ©
Scicli is a town and municipality in the Province of Ragusa in the south east of Sicily, Italy. Kick off your visit on the 15th (Tue): wander the wide-open spaces of Gli Aromi Sicily.

Plan my trip to Scicli with suggested itineraries provided by Inspirock.

Traveling by train from Ragusa to Scicli takes an hour. Alternatively, you can drive. In September in Scicli, expect temperatures between 82°F during the day and 63°F at night. Cap off your sightseeing on the 15th (Tue) early enough to go by car to Noto.
Highlights from your plan
Gli Aromi Sicily ©
Gli Aromi Sicily

few
hours
Noto

Noto
Noto is a city and comune in the Province of Syracuse, Sicily, Italy. Kick off your visit on the 16th (Wed): take in the spiritual surroundings of St. Nicholas Cathedral and then appreciate the extensive heritage of Corso Vittorio Emanuele III.

To see maps, ratings, more things to do, and other tourist information, use the Noto travel planner.

Take a train from Syracuse to Noto in an hour. Alternatively, you can take a bus; or drive. Finish your sightseeing early on the 16th (Wed) to allow enough time to drive to Scicli.

Things to do in Noto

Outdoors Historic Sites Tours

few
hours
Modica

Modica
Modica is a city and comune of 54.456 inhabitants in the Province of Ragusa, Sicily, southern Italy. Kick off your visit on the 17th (Thu): examine the collection at Mulino ad Acqua - Museo Cavallo d'Ispica.

To find other places to visit, where to stay, more things to do, and other tourist information, refer to the Modica holiday planning app .

Modica is just a stone's throw from Scicli. In September, daytime highs in Modica are 82°F, while nighttime lows are 63°F. Wrap up your sightseeing on the 17th (Thu) to allow time to take a bus to Ragusa.

Things to do in Modica

Historic Sites Outdoors Parks

2
nights
Syracuse

Syracuse ©
Philosopher Cicero once described Syracuse as "the greatest Greek city and the most beautiful of them all." A powerful city-state of ancient Greece, Syracuse now is the capital of the eponymous Italian province on the eastern coast of Sicily.
Kick off your visit on the 16th (Wed): get engrossed in the history at Museo Archeologico Regionale Paolo Orsi, delve into the distant past at Parco Archeologico della Neapolis, then explore the ancient world of Ara di Ierone, and finally step off the mainland to explore Ortigia.

For reviews, photos, ratings, and more tourist information, read Syracuse trip itinerary maker website .

Traveling by car from Modica to Syracuse takes 1.5 hours. Alternatively, you can take a bus; or take a train. Wrap up your sightseeing on the 17th (Thu) to allow time to drive to Catania.

Things to do in Syracuse

Parks Nature Historic Sites
Highlights from your plan
Ortigia ©
Ortigia
Parco Archeologico della Neapolis ©
Parco Archeologico della Neapolis
Museo Archeologico Regionale Paolo Orsi ©

1
night
Catania

Catania ©
The landscape surrounding Catania, a medieval city on Sicily's eastern coast, is dominated by Mount Etna, the tallest active volcano in Europe.
On the 17th (Thu), take an in-depth tour of Monastero dei Benedettini, make a trip to Piazza Duomo, ponder the design of Fontana dell'Amenano, admire the striking features of Basilica Catedrale Sant'Agata V.M. Catania, then pause for some photo ops at Fontana dell'Elefante, and finally admire the natural beauty at Giardino Bellini.

To see reviews, photos, other places to visit, and other tourist information, refer to the Catania trip builder tool .

Getting from Syracuse to Catania by car takes about an hour. Other options: take a bus; or take a train. Cap off your sightseeing on the 18th (Fri) early enough to travel to Porto Santo Stefano.

Things to do in Catania

Historic Sites Parks Museums
Highlights from your plan
Piazza Duomo ©
Piazza Duomo
Monastero dei Benedettini ©
Monastero dei Benedettini

1
night
Porto Santo Stefano

Porto Santo Stefano ©
Kick off your visit on the 18th (Fri): stroll through Cala Mar Morto and then stroll through Cala del Gesso.

To see ratings, traveler tips, and more tourist information, use the Porto Santo Stefano trip planner .

The Route module can help you plan travel from Catania to Porto Santo Stefano. In September, daytime highs in Porto Santo Stefano are 81°F, while nighttime lows are 61°F. Wrap up your sightseeing on the 19th (Sat) early enough to travel to Taormina.

Things to do in Porto Santo Stefano

Beaches Parks Outdoors
Highlights from your plan
Cala del Gesso ©
Cala del Gesso

few
hours
Taormina

Taormina ©
With its warm island weather and cliffside location overlooking the Ionion Sea, Taormina has been one of Sicily's most popular getaway destinations since the early 19th century.
Kick off your visit on the 19th (Sat): stroll around Villa Comunale, make a trip to Corso Umberto, and then head off the coast to Isola Bella.

To see where to stay, maps, and more tourist information, you can read our Taormina online trip planner .

Explore your travel options from Porto Santo Stefano to Taormina with the Route module. Traveling from Porto Santo Stefano in September, Taormina is somewhat warmer at night with lows of 69°F. Finish your sightseeing early on the 19th (Sat) so you can drive to Monreale.

Things to do in Taormina

Parks Beaches Outdoors
Highlights from your plan
Isola Bella ©
Isola Bella
Villa Comunale ©
Villa Comunale
Corso Umberto ©
Corso Umberto

1
night
Monreale

Monreale ©
Monreale is a town and comune in the province of Palermo, in Sicily, Italy. On the 20th (Sun), see the interesting displays at Museo Civico "Nicola Barbato", then stop by Vintage Enoteca, then contemplate in the serene atmosphere at Chiostro dei Benedettini, and finally view the masterpieces at Via delle Absidi.

To find other places to visit, traveler tips, and tourist information, you can read our Monreale trip planning app .

Drive from Taormina to Monreale in 3.5 hours. Alternatively, you can take a train; or take a bus. Finish your sightseeing early on the 20th (Sun) to allow enough time to drive to Piazza Armerina.

Things to do in Monreale

Shopping Museums Historic Sites

Side Trip

Museo Civico "Nicola Barbato"
Highlights from your plan
Museo Civico ©
Museo Civico "Nicola Barbato"
Chiostro dei Benedettini ©
Chiostro dei Benedettini

1
night
Piazza Armerina

Piazza Armerina ©
Piazza Armerina is an Italian comune in the province of Enna of the autonomous island region of Sicily.HistoryThe city of Piazza developed during the Norman domination in Sicily, when Lombards settled the central and eastern part of Sicily.But the area had been inhabited since prehistoric times. For more things to do, photos, and more tourist information, go to the Piazza Armerina trip itinerary maker app .

Traveling by car from Monreale to Piazza Armerina takes 2.5 hours. Alternatively, you can take a bus. Wrap up your sightseeing on the 21st (Mon) to allow time to travel to Isnello.

Things to do in Piazza Armerina

Historic Sites Museums

Side Trip

Saint Maria of Monte
Highlights from your plan
Piazza Armerina ©
Piazza Armerina
Villa Romana del Casale
Villa Romana del Casale
Museo della Civilta Contadina ©
Museo della Civilta Contadina

1
night
Isnello

Isnello ©
Isnello is a comune in the Province of Palermo in the Italian region Sicily, located about 70km southeast of Palermo.Isnello borders the following municipalities: Castelbuono, Cefalù, Collesano, Gratteri, Petralia Sottana, Polizzi Generosa, Scillato.Former New York City mayor Vincent R. On the 22nd (Tue), see the interesting displays at Museo Targa Florio, take in the spiritual surroundings of Basilica San Pietro, then see the sky in a new way at GAL Hassin, and finally step into the grandiose world of Castello di Isnello.

For traveler tips, where to stay, other places to visit, and more tourist information, go to the Isnello trip maker site .

Traveling by car from Piazza Armerina to Isnello takes 2 hours. Finish your sightseeing early on the 22nd (Tue) so you can travel to Cefalu.

Things to do in Isnello

Museums Childrens Museums Historic Sites

Side Trip

Collesano
Highlights from your plan
Museo Targa Florio ©
Museo Targa Florio
Basilica San Pietro ©
Basilica San Pietro
GAL Hassin ©
GAL Hassin

2
nights
Cefalu

Cefalu ©
Cefalù is a city and comune in the Province of Palermo, located on the northern coast of Sicily, Italy on the Tyrrhenian Sea about 70km east of the provincial capital and 185km west of Messina. Start off your visit on the 23rd (Wed): wander the streets of Cefalu Coast, take in the awesome beauty at Rocca di Cefalu, make a trip to Lavatoio Medievale, then stop by Enoteca le Petit Tonneau, and finally contemplate the long history of Duomo di Cefalu.

For where to stay, other places to visit, reviews, and tourist information, you can read our Cefalu planner .

You can drive from Isnello to Cefalu in an hour. On the 24th (Thu), wrap the sightseeing up by early afternoon so you can drive to Erice.

Things to do in Cefalu

Historic Sites Parks Nature

Side Trip

Castello di Caccamo
Highlights from your plan
Duomo di Cefalu ©
Duomo di Cefalu
Cefalu Coast ©
Cefalu Coast
Rocca di Cefalu ©
Rocca di Cefalu

3
nights
Erice

Erice ©
Erice is a historic town and comune in the province of Trapani in Sicily, Italy.GeographyErice is located on top of Mount Erice, at around 750m above sea level, overlooking the city of Trapani, the low western coast towards Marsala, the dramatic Punta del Saraceno and Capo San Vito to the north-east, and the Aegadian Islands on Sicily's north-western coast, providing spectacular views.The bordering municipalities are Buseto Palizzolo, Paceco, Trapani, Valderice and Custonaci. Take a break from Erice with a short trip to Cala Mazzo di Sciacca in Scopello, about 50 minutes away. Next up on the itinerary: look for gifts at La Pasticceria Maria Grammatico, make a trip to Chiesa DI San Giuliano, delve into the distant past at Castello di Venere, and identify plant and animal life at Riserva Naturale Orientata Monte Cofano.

Plan my trip to Erice with suggested itineraries provided by Inspirock.

You can drive from Cefalu to Erice in 2.5 hours. Other options are to do a combination of train and bus; or take a bus. You will have some time to spend on the 27th (Sun) before leaving for home.

Things to do in Erice

Parks Outdoors Wildlife

Side Trips

Custonaci, Cala Mazzo di Sciacca
Highlights from your plan
Giardini del Balio ©
Giardini del Balio
La Pasticceria Maria Grammatico ©
La Pasticceria Maria Grammatico
Castello di Venere ©
Castello di Venere

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