21 days in Caribbean, Mexico & South America Itinerary

21 days in Caribbean, Mexico & South America Itinerary

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Route & dates

1
Havana, Cuba
— 3 nights
2
Cancun, Mexico
— 3 nights
3
Cartagena, Colombia
— 2 nights
4
Bogota, Colombia
— 2 nights
5
Quito, Ecuador
— 2 nights
6
Machu Picchu, Peru
— 2 nights
7
Uyuni, Bolivia
— 2 nights
8
Buenos Aires, Argentina
— 3 nights

3
nights
Havana, Cuba

Havana ©
Cuba's capital and major commercial center, Havana manages to be very old and very modern at the same time.
Havana is known for historic sites, nightlife, and museums. Your plan includes some of its best attractions: appreciate the extensive heritage of Malecón of Havana, steep yourself in history at Old Square (Plaza Vieja), make a trip to El Capitolio, and wander the streets of Christopher Columbus Cemetery (Cemetario de Colon).

For traveler tips, other places to visit, maps, and tourist information, read Havana travel itinerary planner.

Doha, Qatar to Havana is an approximately 22.5-hour flight. Due to the time zone difference, you'll gain 8 hours traveling from Doha to Havana. February in Havana sees daily highs of °C and lows of °C at night. Finish your sightseeing early on the 11th (Thu) to allow enough time to travel to Cancun.

Things to do in Havana

Historic Sites Neighborhoods Museums
Highlights from your plan
Malecón of Havana ©
Malecón of Havana
Old Havana ©
Old Havana
Plaza de la Catedral ©
Plaza de la Catedral

3
nights
Cancun, Mexico

Few destinations in Mexico dazzle visitors quite like Cancun, a modern resort town filled with glitzy hotels sitting on picturesque and well-developed Caribbean beaches.
Cancun is known for nightlife, wildlife, and adventure. Your plan includes some of its best attractions: buy something for everyone on your list at La Isla Shopping Village, kick back and relax at Playa Tortugas, get up close and personal with brilliant marine life at Interactive Aquarium, and look for gifts at Joyería Ambarte.

For maps, other places to visit, photos, and other tourist information, refer to the Cancun online trip itinerary maker.

Fly from Havana to Cancun in 4.5 hours. Plan for a bit warmer nights when traveling from Havana in February since evenings lows in Cancun dip to °C. Finish your sightseeing early on the 14th (Sun) to allow enough time to travel to Cartagena.

Things to do in Cancun

Outdoors Parks Tours
Highlights from your plan
Zipline
La Isla Shopping Village ©
La Isla Shopping Village
Swim with Dolphins

2
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Start off your visit on the 15th (Mon): take in the spiritual surroundings of Convent of Santa Cruz de la Popa, thenmake a trip to Castillo de San Felipe de Barajas, thencontemplate the long history of Walled City of Cartagena, and finally pause for some serene contemplation at Sanctuary of Saint Peter Claver. Get ready for a full day of sightseeing on the 16th (Tue): head outdoors with Outdoor Activities, gain insight at Plaza Santo Domingo, thentake an in-depth tour of Museo del Oro Zenu, and finally stop by La Casa del Joyero.

To see more things to do, other places to visit, ratings, and tourist information, go to the Cartagena online journey planner.

Fly from Cancun to Cartagena in 9 hours. Traveling from Cancun in February, expect Cartagena to be a bit warmer, temps between °C and °C. Wrap up your sightseeing on the 16th (Tue) early enough to travel to Bogota.

Things to do in Cartagena

Historic Sites Tours Outdoors
Highlights from your plan
Walled City of Cartagena ©
Walled City of Cartagena
Castillo de San Felipe de Barajas ©
Castillo de San Felipe de Barajas
Boat Tours & Water Sports

2
nights
Bogota, Colombia

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Kick off your visit on the 17th (Wed): explore the world behind art at Museo Botero del Banco de la Republica, examine the collection at Gold Museum (Museo del Oro), and then walk around Parque Metropolitano Simon Bolivar. Keep things going the next day: indulge in some culinary diversions at a local gastronomic tour, take your sightseeing to a higher altitude at Monserrate, and then don't miss a visit to Centro de Memoria El Cuartico.

To find ratings, traveler tips, maps, and tourist information, you can read our Bogota day trip planning website.

Getting from Cartagena to Bogota by flight takes about 3.5 hours. Other options: drive; or take a bus. Traveling from Cartagena in February, you will find days in Bogota are slightly colder (°C), and nights are much colder (°C). Wrap up your sightseeing on the 18th (Thu) to allow time to travel to Quito.

Things to do in Bogota

Museums Parks Tours

Side Trip

Centro de Memoria El Cuartico
Highlights from your plan
Food Tours
Gold Museum (Museo del Oro) ©
Gold Museum (Museo del Oro)
Museo Botero del Banco de la Republica ©
Museo Botero del Banco de la Republica

2
nights
Quito, Ecuador

High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Start off your visit on the 19th (Fri): examine the collection at Museo Camilo Egas, take in the spiritual surroundings of Fundacion Iglesia de la Compania, thenadmire the landmark architecture of Iglesia y Convento de San Francisco, and finally indulge in some culinary diversions at a local gastronomic tour. On the 20th (Sat), you'll have a packed day of sightseeing: take an in-depth tour of Museum of Maria Augusta Urrutia (La Casa Museo Maria Augusta Urrutia) and then stroll around Parque La Carolina.

To see reviews, traveler tips, more things to do, and more tourist information, go to the Quito travel planner.

Getting from Bogota to Quito by flight takes about 6 hours. Other options: drive; or take a bus. Traveling from Bogota in February, you can expect nighttime temperatures to be a bit warmer in Quito, with lows of °C. Wrap up your sightseeing by early afternoon on the 20th (Sat) to allow enough time to travel to Machu Picchu.

Things to do in Quito

Tours Parks Historic Sites
Highlights from your plan
Food Tours
Fundacion Iglesia de la Compania ©
Fundacion Iglesia de la Compania
Iglesia y Convento de San Francisco ©
Iglesia y Convento de San Francisco

2
nights
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Start off your visit on the 21st (Sun): take in nature's colorful creations at Mariposario de Machupicchu and then contemplate the long history of Santuario Historico de Machu Picchu.

To see more things to do, maps, other places to visit, and other tourist information, go to the Machu Picchu trip planner.

You can fly from Quito to Machu Picchu in 12 hours. Other options are to drive; or do a combination of bus and car. Wrap up your sightseeing by early afternoon on the 22nd (Mon) to allow time for travel to Uyuni.

Things to do in Machu Picchu

Historic Sites Parks Wildlife
Highlights from your plan
Santuario Historico de Machu Picchu ©
Santuario Historico de Machu Picchu
Mandor ©
Mandor
Mariposario de Machupicchu ©
Mariposario de Machupicchu

2
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
On the 23rd (Tue), step off the mainland to explore Isla Incahuasi and then explore the striking landscape at Salar de Uyuni.

To see traveler tips, more things to do, where to stay, and other tourist information, read our Uyuni itinerary maker app.

Getting from Machu Picchu to Uyuni by flight takes about 11 hours. Other options: drive; or do a combination of train, bus, and taxi. The time zone difference moving from Peru Standard Time to Bolivia Time is 1 hour. In February, daytime highs in Uyuni are °C, while nighttime lows are °C. On the 24th (Wed), you're off to Buenos Aires.

Things to do in Uyuni

Nature Parks
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi

3
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for historic sites, nightlife, and parks. Your plan includes some of its best attractions: make a trip to Cemiterio de Recoleta, explore the world behind art at Museo de Arte Latinoamericano de Buenos Aires, take in the history at Plaza de Mayo, and visit Puerto Madero.

For maps, other places to visit, more things to do, and tourist information, you can read our Buenos Aires online travel route planner.

You can fly from Uyuni to Buenos Aires in 12 hours. Alternatively, you can drive; or do a combination of taxi and bus. The time zone difference moving from Bolivia Time to Argentina Standard Time is 1 hour. When traveling from Uyuni in February, plan for warmer days and a bit warmer nights in Buenos Aires: temperatures range from °C by day to °C at night. Cap off your sightseeing on the 27th (Sat) early enough to travel back home.

Things to do in Buenos Aires

Museums Historic Sites Shopping
Highlights from your plan
Museo Nacional de Bellas Artes ©
Museo Nacional de Bellas Artes
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero

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