20 days in Panama & Colombia Itinerary

20 days in Panama & Colombia Itinerary

Created using Inspirock trip itinerary planner

Make it your trip
Fly
1
Medellin, Colombia
— 2 nights
Fly
2
Cartagena, Colombia
— 4 nights
Drive
3
Santa Marta, Colombia
— 4 nights
+2
Drive to Ernesto Cortissoz International Airport, Fly to Tocumen International Airport, Drive to San Blas Islands
4
San Blas Islands, Panama
— 4 nights
Fly
5
Bocas Town, Panama
— 2 nights
Fly
6
Panama City, Panama
— 2 nights
Fly

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Medellin, Colombia

— 2 nights

City of the Eternal Spring

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Start off your visit on the 15th (Mon): observe the fascinating underwater world at Parque Explora and then admire the natural beauty at Jardin Botanico de Medellin. On the 16th (Tue), you'll have a packed day of sightseeing: stop by Makeno Tienda.

For where to stay, traveler tips, reviews, and tourist information, read Medellin trip planner.

Lisbon, Portugal to Medellin is an approximately 16-hour flight. You'll gain 5 hours traveling from Lisbon to Medellin due to the time zone difference. In June, daily temperatures in Medellin can reach 33°C, while at night they dip to 20°C. Wrap up your sightseeing on the 17th (Wed) early enough to travel to Cartagena.

Things to do in Medellin

Parks · Tours · Zoos & Aquariums · Museums

Cartagena, Colombia

— 4 nights

City of Heroes

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
You'll discover tucked-away gems like Boats4U and Centro de Convenciones Cartagena de Indias. Next up on the itinerary: take in the architecture and atmosphere at Iglesia de la Trinidad, steep yourself in history at Walled City of Cartagena, make a trip to Plaza Santo Domingo, and take in the spiritual surroundings of Templo de Santo Domingo.

Plan a Cartagena trip in moments using our itinerary builder.

Traveling by flight from Medellin to Cartagena takes 4 hours. Alternatively, you can drive; or take a bus. Expect somewhat warmer temperatures when traveling from Medellin in June; daily highs in Cartagena reach 38°C and lows reach 30°C. On the 21st (Sun), wrap the sightseeing up by early afternoon so you can drive to Santa Marta.

Things to do in Cartagena

Historic Sites · Outdoors · Transportation · Shopping

Side Trip

Santa Marta, Colombia

— 4 nights

America's Pearl

Many visitors begin their Santa Marta holiday, surrounded by urban clutter and heavy traffic, expecting little from the city in terms of historical importance.
You'll explore the less-touristy side of things at El Amanuense Libros & Cafe and Plaza Parque Simon Bolivar. Change things up with these side-trips from Santa Marta: Sierra Nevada de Santa Marta (in Minca) and Parque Nacional Natural Tayrona (in Tayrona National Park). The adventure continues: see the interesting displays at Museo del Oro Tairona - Casa de la Aduana, discover the deep blue sea with a scuba or snorkeling tour, admire the sheer force of Valencia Brook's Waterfalls, and walk around Parque de Los Novios.

For maps, traveler tips, more things to do, and other tourist information, refer to the Santa Marta holiday maker website.

Traveling by car from Cartagena to Santa Marta takes 3.5 hours. Alternatively, you can take a bus. June in Santa Marta sees daily highs of 39°C and lows of 30°C at night. Finish up your sightseeing early on the 25th (Thu) so you can travel to San Blas Islands.

Things to do in Santa Marta

Parks · Nature · Outdoors · Tours

Side Trips

San Blas Islands, Panama

— 4 nights
San Blas Islands represent the offshore area of the indigenous province of Guna Yala.
San Blas Islands is known for nature, spas, and adventure. Your plan includes some of its best attractions: step off the mainland to explore Isla Perro.

For where to stay, traveler tips, ratings, and other tourist information, use the San Blas Islands trip builder site.

Explore your travel options from Santa Marta to San Blas Islands with the Route module. Traveling from Santa Marta in June, you will find days in San Blas Islands are a bit cooler (36°C), and nights are about the same (28°C). On the 29th (Mon), you'll travel to Bocas Town.

Things to do in San Blas Islands

Outdoors · Beaches · Wildlife · Nature
Highlights from your trip

Bocas Town, Panama

— 2 nights
The colorful and relaxed Bocas Town has a welcoming atmosphere, with the modestly sized urban area showcasing typical Caribbean clapboard houses and home to a mixed community from across the world.
On the 29th (Mon), head outdoors with Outdoor Activities.

To see reviews, maps, other places to visit, and tourist information, read our Bocas Town road trip planning tool.

Traveling by flight from San Blas Islands to Bocas Town takes 6 hours. Alternatively, you can do a combination of subway, bus, and ferry; or do a combination of bus and ferry. When traveling from San Blas Islands in June, plan for little chillier days in Bocas Town, with highs around 30°C, while nights are about the same with lows around 30°C. Cap off your sightseeing on the 1st (Wed) early enough to catch the flight to Panama City.

Things to do in Bocas Town

Outdoors · Parks · Wildlife · Beaches

Panama City, Panama

— 2 nights

Dubai of Latin America

Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Kick off your visit on the 2nd (Thu): take in the spiritual surroundings of Bahai Temple, don't miss a visit to Panama Canal, then appreciate the extensive heritage of Casco Viejo, and finally take in the architecture and atmosphere at Iglesia del Carmen. On the 3rd (Fri), you'll have a packed day of sightseeing: don't miss a visit to Amador Causeway (Calzada de Amador) and then get engrossed in the history at Museo del Canal Interoceanico de Panama.

To find reviews, photos, and other tourist information, read Panama City trip builder website.

Traveling by flight from Bocas Town to Panama City takes 2.5 hours. Alternatively, you can do a combination of ferry and bus. When traveling from Bocas Town in July, plan for somewhat warmer days and about the same nights in Panama City: temperatures range from 36°C by day to 29°C at night. Finish your sightseeing early on the 3rd (Fri) so you can travel back home.

Things to do in Panama City

Historic Sites · Neighborhoods · Museums

Colombia travel guide

4
Historic Sites · Landmarks · Specialty Museums
Diverse in terms of landscapes, climates, and cultures, Colombia remains one of South America's least explored tourist destinations, overshadowed by its more popular southern neighbors. Combining the best of what the continent has to offer, a vacation in Colombia allows you to blend outdoor adventures with tours of picture-perfect cobblestoned towns dating back to the colonial era. Tourists on a Colombia holiday can easily hop from sun-kissed coastal spots to the hilly coffee-growing region, where thriving plantations quickly give way to a landscape of snow-covered volcanic peaks and the paramo--alpine ecosystems sheltering some of the rarest plants growing above the continuous forest line.

Panama travel guide

4.1
Landmarks · Historic Walking Areas · Shopping Malls
With a lively banking sector and a booming tourism industry, Panama remains one of the most powerful nations in the Americas, though it's also one of the smallest by land area. The country boasts coastlines on both the Pacific Ocean and the Caribbean Sea, so it's not surprising most Panama holidays include some form of seaside entertainment. With outstanding beaches all over the country, it's easy to find an ideal spot to swim, snorkel, dive, fish, sail, or simply kick back on the sand with a few cold drinks. The country's best-known landmark and one of the world's most significant shipping routes, Panama Canal tops most tourist itineraries--many choose to see this engineering wonder by traveling the length of it by train.