18 days in Northern Argentina, Bolivia & Chile Itinerary

18 days in Northern Argentina, Bolivia & Chile Itinerary

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Route & dates

18 days in Northern Argentina, Bolivia & Chile Itinerary

Start: Montevideo, Uruguay
Fly + Drive:  9​h 30​min
1
Humahuaca, Argentina
— 1 night
Drive:  3​h
2
Salta, Argentina
— 2 nights
Drive:  3​h 30​min
3
Cachi, Argentina
— 3 nights
Drive:  4​h
4
Cafayate, Argentina
— 3 nights
+2
taxi + Fly + taxi:  12​h
5
Uyuni, Bolivia
— 3 nights
Drive:  11​h 30​min
6
San Pedro de Atacama, Chile
— 4 nights
shuttle + Fly:  9​h 30​min
End: Montevideo, Uruguay

1
night
Humahuaca, Argentina

Humahuaca ©
The largest settlement in the Quebrada de Humahuaca, Humahuaca allows for thorough exploration of the colorful valley that links the high Andean lands and the temperate plains of southeastern South America.
Start off your visit on the 11th (Wed): see the interesting displays at Museo Arqueologico Municipal, explore the ancient world of Torre de Santa Barbara, contemplate in the serene atmosphere at Santa Cruz y San Francisco, then take in the architecture and atmosphere at Iglesia de Plaza Central de Humahuaca, then appreciate the history behind Monumento a los Heroes de la Independencia, and finally pause for some serene contemplation at Iglesia San Francisco de Paula. Get ready for a full day of sightseeing on the 12th (Thu): stroll the grounds of Cementerio Nuestra Senora del Carmen, admire the masterpieces at MEC Museo en Los Cerros, then take a memorable drive along Quebrada de Humahuaca, then don't miss a visit to Reloj Solar, and finally take in the architecture and atmosphere at Capilla de la Inmaculada Concepcion.

For ratings, more things to do, reviews, and other tourist information, refer to the Humahuaca attractions planning site .

Montevideo, Uruguay to Humahuaca is an approximately 11-hour combination of flight and car. You can also drive. Wrap up your sightseeing on the 12th (Thu) to allow time to drive to Salta.

Things to do in Humahuaca

Historic Sites Parks Nature

Side Trips

Tilcara, Iglesia San Francisco de Paula
Highlights from your plan
Quebrada de Humahuaca ©
Quebrada de Humahuaca
Iglesia San Francisco de Paula ©
Iglesia San Francisco de Paula
Torre de Santa Barbara ©
Torre de Santa Barbara

2
nights
Salta, Argentina

Salta ©
Salta boasts a vibrant social life and array of informative museums appealing to visitors looking for a memorable cultural experience.
Kick off your visit on the 13th (Fri): explore the striking landscape at El Anfiteatro (The Amphitheatre), get interesting insight from Train to the Clouds, examine the collection at Salta Cabildo, then take a pleasant ride with RETO Cabalgatas, and finally take in the architecture and atmosphere at Iglesia Nuestra Senora de La Candelaria de La Vina. On the 14th (Sat), you'll have a packed day of sightseeing: explore the world behind art at Museo Pajcha Arte Etnico, then make a trip to Calle Balcarce, then contemplate the long history of San Bernardo Convent, and finally make a trip to Monumento General Martín Miguel de Güemes.

To see maps, photos, more things to do, and other tourist information, use the Salta itinerary website .

Drive from Humahuaca to Salta in 3 hours. Alternatively, you can take a bus; or do a combination of bus, taxi, and flight. In December, daytime highs in Salta are 33°C, while nighttime lows are 19°C. Wrap up your sightseeing on the 14th (Sat) to allow time to drive to Cachi.

Things to do in Salta

Tours Museums Historic Sites

Side Trip

RETO Cabalgatas
Highlights from your plan
Train to the Clouds ©
Train to the Clouds
El Anfiteatro (The Amphitheatre) ©
El Anfiteatro (The Amphitheatre)

3
nights
Cachi, Argentina

Cachi ©
Though it's the biggest settlement for miles and locals call it a city, Cachi is really more of a village with a population of just over 2,000.
Popular historic sites such as Parque Nacional Los Cardones and Iglesia San Pedro Nolasco de los Molinos are in your itinerary. Satisfy your inner culture vulture at Cachi Iglesia and Bodega El Molino de Cachi Winery. Take a break from Cachi with a short trip to Cuevas de Acsibi in Seclantas, about 50 minutes away. And it doesn't end there: examine the collection at Museo Arqueologico Pio Pablo Diaz, stop by El Viejo Almacen, and look for all kinds of wild species at Valle Encantado.

To find reviews, more things to do, other places to visit, and tourist information, use the Cachi trip itinerary planning site .

You can drive from Salta to Cachi in 3.5 hours. Finish your sightseeing early on the 17th (Tue) to allow enough time to drive to Cafayate.

Things to do in Cachi

Parks Nature Historic Sites

Side Trips

Cuevas de Acsibi, Iglesia San Pedro Nolasco de los Molinos
Highlights from your plan
Parque Nacional Los Cardones ©
Parque Nacional Los Cardones
Cachi Iglesia ©
Cachi Iglesia
Museo Arqueologico Pio Pablo Diaz ©
Museo Arqueologico Pio Pablo Diaz

3
nights
Cafayate, Argentina

Cafayate ©
Nestled in one of the country's major wine regions, Cafayate and the surrounding area remain a top vacation destination throughout the year.
On the 18th (Wed), stop by Almas Viajeros Taller Artesanias, then do a tasting at Winery Nanni, and then admire the sheer force of Cascadas del Rio Colorado. On the next day, pause for some serene contemplation at Catedral Nuestra Senora del Rosario, don't miss a visit to Plaza Central, then do a tasting at Bodega El Esteco, and finally explore the ancient world of Quilmes Ruins (Ruinas de Quilmes).

To find maps, reviews, more things to do, and other tourist information, use the Cafayate trip itinerary planner.

Drive from Cachi to Cafayate in 4 hours. Wrap up your sightseeing by early afternoon on the 20th (Fri) to allow enough time to travel to Uyuni.

Things to do in Cafayate

Wineries Historic Sites Parks

Side Trip

Quilmes Ruins (Ruinas de Quilmes)
Highlights from your plan
Bodega El Esteco ©
Bodega El Esteco
Quilmes Ruins (Ruinas de Quilmes) ©
Quilmes Ruins (Ruinas de Quilmes)
El Anfiteatro ©
El Anfiteatro

3
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Start off your visit on the 21st (Sat): witness a stunning natural landmark at Aguas Termales de Polques, examine the collection at Necropolis & Museum Kawsay Wasy, then make a trip to San Cristobal de Lipez, then take in the architecture and atmosphere at Iglesia San Cristobal Lipez, and finally witness a stunning natural landmark at Geiser Sol de la Manana. Get ready for a full day of sightseeing on the 22nd (Sun): get outside with Valle De Rocas, then make a trip to Plaza Arce, and then examine the collection at Train Cemetery.

To find ratings, maps, photos, and more tourist information, you can read our Uyuni visit planning site .

Getting from Cafayate to Uyuni by combination of taxi and flight takes about 12 hours. Other options: drive; or do a combination of taxi, bus, car, and train. The time zone difference when traveling from Cafayate to Uyuni is minus 1 hour. In December, plan for daily highs up to 13°C, and evening lows to 13°C. You will have some time to spend on the 23rd (Mon) before leaving for San Pedro de Atacama.

Things to do in Uyuni

Parks Museums Nature

Side Trip

Museo de la Llama y la Sal
Highlights from your plan
Geiser Sol de la Manana ©
Geiser Sol de la Manana
Aguas Termales de Polques ©
Aguas Termales de Polques
Iglesia San Cristobal Lipez ©
Iglesia San Cristobal Lipez

4
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Satisfy your inner culture vulture at Pukara de Quitor and Museo del Meteorito. Eschew the tourist crowds and head to Piedras Rojas and Tebinquinche Lake. Step out of San Pedro de Atacama to go to San Francisco de Chiu Chiu and see Iglesia de San Francisco de Chiu Chiu, which is approximately 1h 40 min away. There's still lots to do: see the sky in a new way at Observatorio Etno-Astronomico, don't miss a visit to Mirador de Kari, Piedra del Coyote, take in the natural beauty of Termas Banos de Puritama, and contemplate the waterfront views at Lagunas Miscanti y Miniques.

To find reviews, ratings, traveler tips, and tourist information, go to the San Pedro de Atacama trip itinerary builder .

You can do a combination of car and bus from Uyuni to San Pedro de Atacama in 11.5 hours. Other options are to drive; or do a combination of car, train, and bus. When traveling from Uyuni in December, plan for much hotter days in San Pedro de Atacama, with highs around 29°C, while nights are little chillier with lows around 6°C. Finish your sightseeing early on the 27th (Fri) so you can travel back home.

Things to do in San Pedro de Atacama

Parks Nature Historic Sites

Side Trip

Iglesia de San Francisco de Chiu Chiu
Highlights from your plan
Piedras Rojas ©
Piedras Rojas
Pukara de Quitor ©
Pukara de Quitor
Iglesia de San Francisco de Chiu Chiu ©

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