16 days in Italy Itinerary

16 days in Italy Itinerary

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Route & dates

16 days in Italy Itinerary

Start: San Francisco
Fly:  18 h
1
Rome
— 4 nights
Train:  2 h 30 min
2
Florence
— 3 nights
Train:  2 h 30 min
3
Venice
— 4 nights
Train:  2 h
4
Milan
— 3 nights
Fly:  3 h 30 min
End: San Francisco

4
nights
Rome

Rome ©
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
You've added Vatican Museums, St. Angelo Bridge, Sistine Chapel, and other attractions to your itinerary. And it doesn't end there: delve into the distant past at Colosseum, pause for some serene contemplation at Santa Maria in Trastevere, get to know the fascinating history of Piazza Navona, and make a trip to Spanish Steps.

Find out how to plan Rome trip without stress by asking Inspirock to help create an itinerary.

San Francisco, USA to Rome is an approximately 18- hour flight. You can also do a combination of flight and train; or do a combination of train and flight. The time zone difference moving from Pacific Standard Time (PST) to Central European Time (CET) is 9 hours. Expect little chillier evenings in Rome when traveling from San Francisco in March, with lows around 45°F. Wrap up your sightseeing on the 12th (Thu) to allow time to take a train to Florence.

Things to do in Rome

Historic Sites Museums Shopping

Side Trip

Vatican City
Highlights from your plan
Colosseum ©
Colosseum
Pantheon ©
Pantheon
Trevi Fountain ©
Trevi Fountain

3
nights
Florence

Florence ©
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Your list of things to see and do now includes Museo di San Marco, Museo Nazionale del Bargello, Piazza della Repubblica, and other attractions. The adventure continues: explore the world behind art at Academy Of Florence Art Gallery, steep yourself in history at L’importuno di Michelangelo, appreciate the extensive heritage of Piazza del Duomo, and take in the views from Ponte Vecchio.

For other places to visit, ratings, reviews, and other tourist information, use the Florence day trip website.

Traveling by train from Rome to Florence takes 2 hours. Alternatively, you can drive; or fly. March in Florence sees daily highs of 59°F and lows of 42°F at night. On the 15th (Sun), wrap the sightseeing up by early afternoon so you can take a train to Venice.

Things to do in Florence

Museums Historic Sites Shopping
Highlights from your plan
Gallerie Degli Uffizi ©
Gallerie Degli Uffizi
Academy Of Florence Art Gallery ©
Academy Of Florence Art Gallery
Piazzale Michelangelo ©
Piazzale Michelangelo

4
nights
Venice

Venice ©
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
You've added Basilica di Santa Maria Gloriosa dei Frari, Centro Storico di Venezia, Torcello Island, and other attractions to your itinerary. There's lots more to do: explore the activities along Canal Grande, admire the masterpieces at Gallerie dell'Accademia, make a trip to Piazza San Marco, and pause for some serene contemplation at San Giorgio Maggiore.

For more things to do, other places to visit, and more tourist information, read our Venice trip planner.

Getting from Florence to Venice by train takes about 2.5 hours. Other options: drive; or take a bus. In March, daytime highs in Venice are 58°F, while nighttime lows are 41°F. On the 19th (Thu), wrap the sightseeing up by early afternoon so you can take a train to Milan.

Things to do in Venice

Historic Sites Museums Neighborhoods

Side Trips

Isola di Murano, Discover Burano
Highlights from your plan
Canal Grande ©
Canal Grande
Doge's Palace ©
Doge's Palace
Basilica di San Marco
Basilica di San Marco

3
nights
Milan

Milan ©
In many ways the most modern of Italian cities, Milan is a busy, elegant metropolis with an impressive list of grand palaces, fine churches, and important museums.
Your day-by-day itinerary now includes Arco della Pace as well as Colonne di San Lorenzo. Get ready for a full day of sightseeing on the 20th (Fri): explore the world behind art at Pinacoteca di Brera, contemplate the long history of Castello Sforzesco, then pause for some photo ops at Arco della Pace, and finally contemplate the long history of Il Cenacolo.

To see ratings, where to stay, traveler tips, and more tourist information, read our Milan road trip site.

Getting from Venice to Milan by train takes about 2.5 hours. Other options: drive; or do a combination of train and flight. March in Milan sees daily highs of 57°F and lows of 40°F at night. Cap off your sightseeing on the 22nd (Sun) early enough to travel back home.

Things to do in Milan

Historic Sites Museums Shopping
Highlights from your plan
Duomo di Milano ©
Duomo di Milano
Galleria Vittorio Emanuele II ©
Galleria Vittorio Emanuele II
Pinacoteca Ambrosiana ©
Pinacoteca Ambrosiana

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