15 days in San Pedro de Atacama, Uyuni & Santiago Itinerary

15 days in San Pedro de Atacama, Uyuni & Santiago Itinerary

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Route & dates

15 days in San Pedro de Atacama, Uyuni & Santiago Itinerary

Start: Sao Paulo, Brazil
+2
bus + Fly + shuttle:  12​h 30​min
1
San Pedro de Atacama, Chile
— 6 nights
Drive:  11​h 45​min
2
Uyuni, Bolivia
— 3 nights
taxi + Fly:  11​h 45​min
3
Santiago, Chile
— 5 nights
Fly:  6​h 15​min
End: Sao Paulo, Brazil

6
nights
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
When in San Pedro de Atacama, make a side trip to see Salar de Atacama in Antofagasta, approximately 1h 35 min away. Next up on the itinerary: explore the striking landscape at Valle De La Luna, witness a stunning natural landmark at Geyser del Tatio, contemplate the waterfront views at Lagunas Altiplanicas, and see the sky in a new way at Observatorio Etno-Astronomico Licanantay.

To see where to stay, other places to visit, photos, and other tourist information, you can read our San Pedro de Atacama trip maker website .

Sao Paulo, Brazil to San Pedro de Atacama is an approximately 12.5-hour combination of bus, flight, and shuttle. You can also do a combination of bus and flight; or drive. Traveling from Sao Paulo to San Pedro de Atacama, you'll gain 1 hour due to the time zone difference. Expect little chillier weather when traveling from Sao Paulo in February: highs in San Pedro de Atacama hover around 28°C, while lows dip to 8°C. Finish your sightseeing early on the 7th (Fri) so you can drive to Uyuni.

Things to do in San Pedro de Atacama

Parks Nature Wildlife

Side Trip

Salar de Atacama
Highlights from your plan
Geyser del Tatio ©
Geyser del Tatio
Valle De La Luna ©
Valle De La Luna
Lagunas Miscanti y Miniques ©
Lagunas Miscanti y Miniques

3
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Step out of Uyuni with an excursion to Museo de la Llama y la Sal in Colchani--about 54 minutes away. There's much more to do: explore the striking landscape at Salar de Uyuni, head off the coast to Isla Incahuasi, get a new perspective on nature at Museo Arquecologia y Antropologico de los Andes Meridionales, and take in the architecture and atmosphere at Iglesia San Cristobal Lipez.

For where to stay, reviews, more things to do, and other tourist information, read Uyuni trip itinerary builder .

You can drive from San Pedro de Atacama to Uyuni in 12 hours. Other options are to do a combination of bus and taxi; or take a bus. Traveling from San Pedro de Atacama in February, you will find days in Uyuni are cooler (13°C), and nights are somewhat warmer (12°C). On the 10th (Mon), you'll travel to Santiago.

Things to do in Uyuni

Nature Parks Museums

Side Trip

Museo de la Llama y la Sal
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi
Train Cemetery ©
Train Cemetery

5
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Explore Santiago's surroundings by going to La Sebastiana (in Valparaiso) and Concha y Toro (in Pirque). There's still lots to do: take your sightseeing to a higher altitude at San Cristóbal Hill, explore the world behind art at Museo Chileno de Arte Precolombino, take in the pleasant sights at Plaza de Armas, and examine the collection at La Chascona.

To see more things to do, reviews, other places to visit, and more tourist information, read Santiago holiday maker app .

Traveling by combination of taxi and flight from Uyuni to Santiago takes 12 hours. Alternatively, you can drive; or do a combination of taxi and bus. Cap off your sightseeing on the 15th (Sat) early enough to travel back home.

Things to do in Santiago

Museums Parks Nature

Side Trips

Concha y Toro, La Sebastiana
Highlights from your plan
San Cristóbal Hill ©
San Cristóbal Hill
Cerro Santa Lucia ©
Cerro Santa Lucia
Patio Bellavista ©
Patio Bellavista

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