11 days in Panama City, Cartagena & Medellin Itinerary

11 days in Panama City, Cartagena & Medellin Itinerary

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Route & dates

11 days in Panama City, Cartagena & Medellin Itinerary

Start: New York City, United States
Fly:  8 h 30 min
1
Panama City, Panama
— 3 nights
Fly:  2 h
2
Cartagena, Colombia
— 4 nights
Fly:  4 h
3
Medellin, Colombia
— 3 nights
Fly:  9 h 15 min
End: New York City, United States

3
nights
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Get a sense of the local culture at Casco Viejo and Avenida Balboa. Museo del Canal Interoceanico de Panama and Centro de Interpretacion de Ciudad del Saber will appeal to museum buffs. Next up on the itinerary: explore the wealth of natural beauty at Soberania National Park, pause for some serene contemplation at Iglesia del Carmen, explore the ancient world of Panama La Vieja, and contemplate the long history of Iglesia de San José.

To find photos, more things to do, traveler tips, and tourist information, go to the Panama City online travel route planner .

New York City, USA to Panama City is an approximately 8.5-hour combination of bus and flight. You can also fly; or drive. In February, Panama City is much warmer than New York City - with highs of 89°F and lows of 76°F. Wrap up your sightseeing on the 10th (Mon) early enough to travel to Cartagena.

Things to do in Panama City

Historic Sites Nature Parks
Highlights from your plan
Casco Viejo ©
Casco Viejo
Soberania National Park ©
Soberania National Park

4
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Get a sense of the local culture at Castillo de San Felipe de Barajas and Plaza Santo Domingo. Deepen your sense of the past at sights like Walled City of Cartagena and Convent of Santa Cruz de la Popa. When in Cartagena, make a side trip to see Playa Blanca in Isla Baru, approximately 1h 05 min away. There's much more to do: take a tour by water with Tours in Rosario islands, pause for some serene contemplation at Sanctuary of Saint Peter Claver, examine the collection at Museo Historico de Cartagena de Indias, and take an in-depth tour of Museo del Oro Zenu.

For more things to do, traveler tips, other places to visit, and tourist information, refer to the Cartagena trip maker tool .

Getting from Panama City to Cartagena by flight takes about 2 hours. In February, daytime highs in Cartagena are 88°F, while nighttime lows are 75°F. Wrap up your sightseeing on the 14th (Fri) early enough to travel to Medellin.

Things to do in Cartagena

Outdoors Historic Sites Tours

Side Trip

Playa Blanca
Highlights from your plan
Castillo de San Felipe de Barajas ©
Castillo de San Felipe de Barajas
Playa Blanca ©
Playa Blanca
Walled City of Cartagena ©
Walled City of Cartagena

3
nights
Medellin, Colombia

Medellin ©
Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Kick off your visit on the 15th (Sat): relax and rejuvenate at some of the top local wellness centers, then get engrossed in the history at Museo de Antioquia, and then contemplate the long history of Pueblito Paisa. On the 16th (Sun), you'll have a packed day of sightseeing: soar above the sights with a balloon tour and then look for all kinds of wild species at Parque Arvi.

To find where to stay, ratings, reviews, and more tourist information, use the Medellin journey builder website .

You can fly from Cartagena to Medellin in 4 hours. Other options are to do a combination of bus and flight; or drive. Traveling from Cartagena in February, expect Medellin to be a bit cooler, temps between 82°F and 64°F. You will have some time to spend on the 17th (Mon) before leaving for home.

Things to do in Medellin

Parks Wildlife Museums
Highlights from your plan
Parque Arvi ©
Parque Arvi
Museo de Antioquia ©
Museo de Antioquia
Balloon Rides

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