10 days in Southeast Missouri Itinerary

10 days in Southeast Missouri Itinerary

Created using Inspirock Southeast Missouri trip itinerary maker

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Make it your trip
Drive
1
Sainte Genevieve
— 3 nights
Drive
2
Cape Girardeau
— 3 nights
Drive
3
New Madrid
— 1 night
Drive
4
Eminence
— 1 night
Drive
5
New Haven
— 1 night
Drive

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Sainte Genevieve

— 3 nights
Ste. Venture out of the city with trips to Bonne Terre (The Space Museum, Bonne Terre Mine Tours - West End Diving, &more), Arcadia Valley (in Arcadia) and Johnson's Shut-ins State Park (in Middle Brook). There's much more to do: steep yourself in history at Felix Valle House State Historic Site, learn about winemaking at Watertower Winery, immerse yourself in nature at Hawn State Park, and pause for some serene contemplation at Sainte Genevieve Catholic Parish.

For where to stay, photos, more things to do, and tourist information, read our Sainte Genevieve online road trip planner.

Saint Louis to Sainte Genevieve is an approximately 1.5-hour car ride. In December, daily temperatures in Sainte Genevieve can reach 43°F, while at night they dip to 30°F. Wrap up your sightseeing on the 1st (Fri) early enough to drive to Cape Girardeau.

Things to do in Sainte Genevieve

Parks · Nature · Wineries · Museums

Side Trips

Cape Girardeau

— 3 nights
Cape Girardeau is a city in Cape Girardeau and Scott counties in the U.S. Cape Girardeau is known for casinos, parks, and wildlife. Your plan includes some of its best attractions: look for all kinds of wild species at Cape Girardeau Conservation Nature Center, don't miss a visit to Glenn House, stroll through Trail of Tears, and have fun and explore at Discovery Playhouse.

For maps, where to stay, more things to do, and more tourist information, read our Cape Girardeau trip builder website.

Getting from Sainte Genevieve to Cape Girardeau by car takes about 1.5 hours. In January in Cape Girardeau, expect temperatures between 43°F during the day and 24°F at night. Wrap up your sightseeing on the 4th (Mon) early enough to drive to New Madrid.

Things to do in Cape Girardeau

Parks · Historic Sites · Childrens Museums · Nature

Side Trip

New Madrid

— 1 night
New Madrid is a city in New Madrid County, Missouri, United States. Start off your visit on the 5th (Tue): contemplate the long history of Hunter-Dawson State Historic Site, take an in-depth tour of Higgerson School Historic Site, then get a taste of the local shopping with New Madrid Historical Museum, and finally take in panoramic vistas at Mississippi River Observation Deck.

To find maps, photos, where to stay, and more tourist information, read New Madrid trip app.

Drive from Cape Girardeau to New Madrid in an hour. In January, plan for daily highs up to 42°F, and evening lows to 24°F. Finish up your sightseeing early on the 5th (Tue) so you can travel to Eminence.

Things to do in New Madrid

Museums · Historic Sites · Shopping

Eminence

— 1 night
Eminence is a city in Shannon County, Missouri, United States. On the 6th (Wed), explore the wealth of natural beauty at Alley Spring Grist Mill Historic Site.

To find photos, reviews, where to stay, and tourist information, go to the Eminence visit planner.

Drive from New Madrid to Eminence in 2.5 hours. Expect a daytime high around 45°F in January, and nighttime lows around 24°F. Wrap up your sightseeing on the 6th (Wed) to allow time to travel to New Haven.

Things to do in Eminence

Nature · Parks

New Haven

— 1 night
New Haven is a city in Franklin County, Missouri, United States. Start off your visit on the 7th (Thu): learn about winemaking at Robller Vineyard, then take in the exciting artwork at Astral Glass Studio and Gallery, then sample the fine beverages at Pinckney Bend Distillery, and finally appreciate the extensive heritage of John Colter Memorial.

For reviews, maps, traveler tips, and other tourist information, go to the New Haven day trip planning app.

Traveling by car from Eminence to New Haven takes 3 hours. In January, daily temperatures in New Haven can reach 41°F, while at night they dip to 22°F. Finish your sightseeing early on the 7th (Thu) to allow enough time to drive back home.

Things to do in New Haven

Wineries · Shopping · Museums · Breweries & Distilleries